Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,841 recruiting studies in this area right now.
By phase
- Not applicable3,975
- Phase 2223
- Phase 4196
- Phase 1191
- Phase 3149
- Phase 1/Phase 274
- Phase 2/Phase 333
Top conditions
- Knee Osteoarthritis185
- Rheumatoid Arthritis142
- Fibromyalgia102
- Osteoporosis88
- Osteoarthritis74
- Osteoarthritis, Knee72
- Rheumatoid Arthritis (RA)64
- Shoulder Pain50
- Psoriatic Arthritis47
- Hip Osteoarthritis41
- Systemic Lupus Erythematosus41
- Duchenne Muscular Dystrophy39
- Chronic Pain38
- Degenerative Disc Disease38
- Total Knee Arthroplasty38
- Musculoskeletal Pain36
- Pain35
- Dermatomyositis31
Leading sponsors
- Riphah International University110
- Cairo University72
- Istituto Ortopedico Rizzoli71
- Assistance Publique - Hôpitaux de Paris37
- Foundation University Islamabad34
- Mayo Clinic29
- Massachusetts General Hospital27
- National Taiwan University Hospital25
- Chinese University of Hong Kong22
- Hacettepe University22
Where studies are running
- California210
- New York94
- Florida80
- Massachusetts76
- Arizona75
- Maryland73
- Texas65
- Alabama57
- Illinois54
- Pennsylvania50
Recruiting studies4,841 total
- NCT07336160Recruiting
Nutrition before knee replacement surgery
This trial studies a special nutrition plan before knee replacement surgery to see if it helps recovery. Participants follow enhanced recovery guidelines for eating and drinking before their operation.
Istanbul, IstanbulAges 18 years+ - NCT07336303Recruiting
Ear acupuncture for thumb surgery pain
This study tests whether ear acupuncture (auriculotherapy) helps reduce pain after thumb arthritis surgery. If you're having this surgery and haven't tried ear acupuncture before, you may be able to join.
ParisAges 18 years+ - NCT07333560Recruiting
Predicting recovery after hip or knee replacement
This study is developing a tool that uses machine learning to predict how well you will recover after hip or knee replacement surgery. It aims to help doctors create better recovery plans for people like you.
BolognaAges 18 years+ - NCT07329530Recruiting
Muscle and metabolism study in ICU survivors
This study looks at muscle and metabolism changes in people who have been in the ICU for at least 7 days after major abdominal surgery. It aims to understand how recovery affects the body.
LiègeAges 18 years+ - NCT06790628Recruiting
Rebuilding jaw symmetry with leg bone flap
This study compares two ways to rebuild a large missing section of your lower jaw using a piece of your own leg bone (called a fibula flap). The goal is to see which method creates better facial symmetry and a more natural result.
Cairo, Cairo GovernorateAges Any age - NCT07329361Recruiting
Frozen platelet-rich plasma injections for knee osteoarthritis
This trial tests whether frozen platelet-rich plasma (PRP) injections into the knee can safely reduce pain and improve function in people with knee osteoarthritis. It's for those with mild to moderate knee arthritis who haven't had certain recent knee treatments.
Vitoria-Gasteiz, Araba/ÁlavaAges 40–85 - NCT07324954RecruitingPhase 1
Methylene blue for knee replacement surgery
This study tests if using a blue dye called methylene blue during knee replacement surgery can help doctors see and clean out infections better. It may help people having a first-time knee replacement or those with an infected knee replacement.
Miami, FloridaAges 18 years+ - NCT06491121Recruiting
Can high-intensity training with a smartphone help chronic back pain?
This trial tests if a technology-supported high-intensity exercise program can help adults with chronic low back pain. You'll use your own smartphone to help guide the training and attend regular therapy sessions.
Wilrijk, AntwerpenAges 18–65 - NCT06359665Enrolling by invitationPhase 1
Oral curcumin for thumb arthritis pain
This trial tests whether an oral curcumin supplement can help reduce pain from thumb arthritis. If you are an adult with daily thumb pain of at least moderate severity and have not taken turmeric or blood thinners, this may be an option for you.
Charlottesville, VirginiaAges 18 years+ - NCT07321600Recruiting
Breathing muscle training with Schroth exercises for scoliosis in teens
This trial tests whether adding a special breathing exercise (inspiratory muscle training) to standard Schroth exercises improves breathing and posture in teenage girls with scoliosis. It may help strengthen the muscles used for breathing.
Kırşehir, MerkezAges 10–18 - NCT07318298Recruiting
Hyaluronic acid injection for wisdom tooth socket healing
This trial tests if injecting hyaluronic acid into the sockets after wisdom tooth removal helps bone heal faster. It may be an option if you need both lower wisdom teeth removed and are generally healthy.
IrbidAges 18–35 - NCT07313215Recruiting
Study of rifampin combo therapy for staph joint infections
This study tests whether adding rifampin to standard antibiotics works better for people with a staph infection in a joint replacement. It aims to find a more effective treatment for this type of infection.
Fuzhou, FujianAges 18–80 - NCT06493318Recruiting
Wrist ligament surgery study: long-term results
This study looks at how well a specific wrist surgery (dorsal ligamentoplasty with an internal brace) works over time for people with scapholunate instability, a condition where the bones in the wrist are not stable. It aims to understand the long-term outcomes and help doctors know if this surgery is a good option.
MarseilleAges 18 years+ - NCT07090122Recruiting
Spinal tumor treatment: ablation plus radiation vs radiation alone
This study compares two treatments for cancer that has spread to the spine. One group receives radiofrequency ablation (a heat-based treatment to destroy tumor cells) plus bone strengthening, followed by radiation. The other group receives radiation alone. The goal is to see which approach better controls pain and prevents spine problems.
Minneapolis, MinnesotaAges 18 years+ - NCT07313020Enrolling by invitationEarly Phase 1
Handheld imaging to track stem cells in knee osteoarthritis
This trial tests a new handheld imaging device (MPI) to track stem cells injected into the knee. It aims to see if the device can safely monitor how the stem cells move and work in people with knee osteoarthritis.
Haikou, HainanAges 18–75 - NCT06931951Recruiting
Acupuncture with medicine for knee pain after a car accident
This trial tests a type of acupuncture that injects medicine into specific points (pharmacopuncture) to treat severe knee pain from a recent traffic accident. It looks at whether this treatment is safe and effective for people who are already in the hospital for their injury.
DaejeonAges 19–69 - NCT06924164Recruiting
Strength training for snapping hip syndrome
This trial tests if progressive strength training can reduce pain and snapping in adults with external snapping hip. If you have a snapping or popping sensation on the outside of your hip with discomfort, this study may help find a non-surgical treatment option.
AalborgAges 18–40 - NCT07598487Enrolling by invitation
Physical Therapy Techniques for Stroke Recovery and Balance
This study compares two types of physical therapy to help people regain trunk control and balance after a stroke. Participants will receive either PNF (a hands-on technique using rhythmic movements) or NDT (another hands-on technique focusing on movement patterns) to improve stability.
Faisalabad, Punjab ProvinceAges 40–65 - NCT07309796Recruiting
Strengthening exercises after reverse shoulder replacement
This study tests whether specific strengthening exercises for the shoulder muscles that help lift your arm can improve recovery after a reverse total shoulder replacement. You will be randomly assigned to receive these exercises or standard care, and your progress will be tracked.
KırşehirAges 65–90 - NCT05868863Recruiting
Cement procedure for pelvic bone lesions with or without screws
This trial reviews a procedure that uses bone cement to treat a lesion in the pelvis, sometimes with added screw support. It aims to understand outcomes for patients having cement treatment, with or without screws.
Saint-EtienneAges 80 years+ - NCT07307950Recruiting
Testing an app to improve rehab for kids with movement disabilities
This study tests a new app designed to help families and therapists coordinate care for children with movement disabilities. It aims to make rehabilitation easier and more connected across different care settings.
BrestAges 2–25 - NCT06904703Recruiting
Nerve blocks for older adults having hip replacement surgery
This trial tests two types of nerve blocks to see which one works better for pain control in older adults undergoing total hip replacement. A nerve block is a shot of anesthetic near a nerve to numb a specific area, and the goal is to help you feel less pain after surgery.
TantaAges 75 years+ - NCT06797050Recruiting
Robot helper story for children with movement challenges
This study tests whether interacting with a robot helper named Nao can help children with movement difficulties learn new skills. The robot tells a story and guides activities to improve motor and thinking abilities.
Bosisio Parini, LeccoAges 7–16 - NCT06973642Recruiting
Home-based rehab after ACL surgery via phone
This trial tests whether a home-based rehab program using your phone can help people recover after anterior cruciate ligament (ACL) reconstruction. It aims to see if remote physical therapy is as effective as in-person sessions.
Jackson, MississippiAges 18 years+
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,841 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,937 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.