Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,841 recruiting studies in this area right now.
By phase
- Not applicable3,975
- Phase 2223
- Phase 4196
- Phase 1191
- Phase 3149
- Phase 1/Phase 274
- Phase 2/Phase 333
Top conditions
- Knee Osteoarthritis185
- Rheumatoid Arthritis142
- Fibromyalgia102
- Osteoporosis88
- Osteoarthritis74
- Osteoarthritis, Knee72
- Rheumatoid Arthritis (RA)64
- Shoulder Pain50
- Psoriatic Arthritis47
- Hip Osteoarthritis41
- Systemic Lupus Erythematosus41
- Duchenne Muscular Dystrophy39
- Chronic Pain38
- Degenerative Disc Disease38
- Total Knee Arthroplasty38
- Musculoskeletal Pain36
- Pain35
- Dermatomyositis31
Leading sponsors
- Riphah International University110
- Cairo University72
- Istituto Ortopedico Rizzoli71
- Assistance Publique - Hôpitaux de Paris37
- Foundation University Islamabad34
- Mayo Clinic29
- Massachusetts General Hospital27
- National Taiwan University Hospital25
- Chinese University of Hong Kong22
- Hacettepe University22
Where studies are running
- California210
- New York94
- Florida80
- Massachusetts76
- Arizona75
- Maryland73
- Texas65
- Alabama57
- Illinois54
- Pennsylvania50
Recruiting studies4,841 total
- NCT04641039Recruiting
Study of scar differences after lumbar disc replacement
This study compares how postoperative scars look and behave after certain lumbar disc replacement surgery. It may help doctors choose approaches that reduce excessive scar-related problems after surgery.
Valencia, ValenciaAges 18–50 - NCT07301476Recruiting
Testing numbing medicine spread in a knee block
This trial checks how a numbing medicine moves during a common knee block for surgery. It may help doctors improve pain control after knee operations.
Boulogne-BillancourtAges 18 years+ - NCT06895564Recruiting
Proton radiation for hard-to-treat spine tumors
This trial tests a special type of proton radiation for people whose spine cancer has spread from another part of the body and cannot be treated effectively with standard X-ray radiation. The goal is to see if proton radiation can safely deliver a high dose of radiation to the tumor.
Baltimore, MarylandAges 18 years+ - NCT06799377Recruiting
Activity and healing in children's forearm fractures
This study looks at how activity affects healing in children with certain forearm fractures that don't need surgery. The goal is to learn if specific activities can cause the bone to shift out of place.
Nashville, TennesseeAges 8–18 - NCT05329558Enrolling by invitation
Testing changes in jawbone problems in adults
This study looks at what changes happen in the jawbone in people with osteonecrosis of the jaw (a damaged jawbone area), whether or not they take certain cancer/bone medicines. It may help doctors better understand the condition and how it behaves over time.
GrazAges 18 years+ - NCT06800079Recruiting
Elastic band training for knee strength in female soccer players
This trial tests whether elastic band exercises can improve knee strength and performance in female soccer players. If you play on a U-15, U-19, or senior women's team and compete in a district or national championship, you may be able to join.
Maia, Porto DistrictAges Any age - NCT06328114Enrolling by invitationPhase 2
Brain stimulation for cervical dystonia
This study tests a type of brain stimulation called TMS to see if it can improve neck muscle spasms in people with cervical dystonia. It's for adults who haven't had Botox recently and are not on other treatments.
Durham, North CarolinaAges 18 years+ - NCT02906865Recruiting
Study of surgery outcomes for hamstring rupture
This study follows people who had a hamstring muscle tear near the hip that was repaired with surgery. It aims to better understand recovery after surgery in cases confirmed by MRI.
ParisAges 10 years+ - NCT07297459Enrolling by invitation
Surgery options for a jaw joint problem
This trial compares two types of surgery to treat a common jaw joint problem where the disc slips out of place. It looks at which procedure works better for reducing pain and improving function.
StockholmAges 18 years+ - NCT07296471Recruiting
Vitamin D and Bone Health Study
This study is looking at how vitamin D levels relate to bone health and overall health markers in people with and without osteoporosis. It aims to find better ways to understand and treat bone loss.
Yichang, HubeiAges 18 years+ - NCT05925452Recruiting
Genalumab for children with active systemic juvenile arthritis
This trial studies whether a medicine called genalumab can reduce inflammation and improve symptoms in children with active systemic juvenile idiopathic arthritis (sJIA). It also checks how safe the treatment is, including possible side effects.
Beijing, BenjingAges 2–17 - NCT06802419Recruiting
Comparing two types of knee nerve blocks for pain relief after knee surgery
This study compares two types of nerve blocks—one that numbs the front of the thigh and one that adds extra numbing behind the knee—to see which provides better pain relief after arthroscopic knee surgery (like ACL or PCL repair). The goal is to help patients have less pain and recover more comfortably.
CairoAges 21–65 - NCT07294651Recruiting
Needle treatment for chronic neck pain
This trial is testing a procedure called percutaneous electrolysis, where a tiny needle is used to treat painful trigger points in the upper neck muscles. It may help people with long-lasting neck pain.
SivasAges 18–70 - NCT07294417Recruiting
Bone cement screws vs. special screws for weak spine bones
This study compares two types of screws used to fix spine fractures or instability in people with brittle bones (osteoporosis). One type uses bone cement to strengthen the screw, and the other uses a special hollow screw. The goal is to see which method works better for reducing pain and stabilizing the spine.
Kafr ash Shaykh, KafrelsheikhAges 18 years+ - NCT06934278RecruitingPhase 3
Plasma vs salt water for scoliosis surgery in kids
This study compares two types of fluids—one made from donated human blood plasma and one a standard salt-solution—given during scoliosis surgery in children and teenagers. The goal is to see which fluid helps patients recover safely and with fewer complications.
HelsinkiAges 10–21 - NCT06906094Enrolling by invitation
Preventing arthritis after meniscus tear surgery
This trial tests a new approach to prevent arthritis after surgery to remove part of a torn meniscus. It looks at whether a treatment can stop the knee from wearing down after the operation.
Milan, MilanoAges 19 years+ - NCT06803914Recruiting
Returning to sports after hip replacement
This study looks at how people move and return to sports after total hip replacement surgery. If you are an active person planning to have a hip replacement, this trial may help understand your recovery.
MérignacAges 18–65 - NCT06969859Recruiting
Pulsed electromagnetic field therapy for Achilles tendon pain
This study tests if pulsed electromagnetic field (PEMF) therapy can help people with mid-portion Achilles tendinopathy (pain and swelling in the middle of the Achilles tendon). It aims to see if this non-invasive treatment can reduce pain and improve function.
Shatin, New TerritoriesAges 18 years+ - NCT07291765Recruiting
Using Blood Flow Restriction in Hip Fracture Rehab
This trial tests whether using a special blood pressure cuff during rehab exercises can help older adults recover faster after a hip fracture.
Cologne, North Rhine-WestphaliaAges 65 years+ - NCT06939491Enrolling by invitation
Ultrasound-guided electrolysis vs. sham for patellar tendon pain
This trial tests whether a treatment called ultrasound-guided electrolysis therapy can reduce pain and improve tendon health in people with patellar tendinopathy (knee tendon pain). It compares the real treatment to a sham (fake) treatment to see if it works better.
Bremen, Free Hanseatic City of BremenAges 18–59 - NCT06805396RecruitingPhase 2
Adding palliative care support during radiation for bone cancer pain
This study tests whether adding a palliative care team early while you receive radiation for bone metastases can improve your quality of life and reduce symptoms.
AmersfoortAges Any age - NCT06969625Recruiting
Shoulder Block for Pain Relief After Rotator Cuff Surgery
This study tests a special numbing injection (shoulder block) to see how well it controls pain after arthroscopic rotator cuff repair. If you are having this type of shoulder surgery and are generally healthy, this trial may help you recover with less pain.
Zagazig, Al SharqiaAges 21–65 - NCT07344025Recruiting
Comparing two bone graft materials for tooth socket preservation
This trial tests two different bone graft materials used to preserve the jawbone after a tooth extraction. The goal is to see which material works better to maintain bone for future dental implants.
AlexandriaAges 21–50 - NCT07289737Recruiting
Comparing two spine surgeries for a slipped backbone
This study compares two types of spine surgery for a common condition where a lower back bone slips forward. It aims to see which surgery works better to relieve pain and improve function.
Yiwu, ZhejiangAges 50–90
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,841 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,937 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.