Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,841 recruiting studies in this area right now.
By phase
- Not applicable3,975
- Phase 2223
- Phase 4196
- Phase 1191
- Phase 3149
- Phase 1/Phase 274
- Phase 2/Phase 333
Top conditions
- Knee Osteoarthritis185
- Rheumatoid Arthritis142
- Fibromyalgia102
- Osteoporosis88
- Osteoarthritis74
- Osteoarthritis, Knee72
- Rheumatoid Arthritis (RA)64
- Shoulder Pain50
- Psoriatic Arthritis47
- Hip Osteoarthritis41
- Systemic Lupus Erythematosus41
- Duchenne Muscular Dystrophy39
- Chronic Pain38
- Degenerative Disc Disease38
- Total Knee Arthroplasty38
- Musculoskeletal Pain36
- Pain35
- Dermatomyositis31
Leading sponsors
- Riphah International University110
- Cairo University72
- Istituto Ortopedico Rizzoli71
- Assistance Publique - Hôpitaux de Paris37
- Foundation University Islamabad34
- Mayo Clinic29
- Massachusetts General Hospital27
- National Taiwan University Hospital25
- Chinese University of Hong Kong22
- Hacettepe University22
Where studies are running
- California210
- New York94
- Florida80
- Massachusetts76
- Arizona75
- Maryland73
- Texas65
- Alabama57
- Illinois54
- Pennsylvania50
Recruiting studies4,841 total
- NCT07358507Recruiting
Nerve exercises for inner wrist pain relief
This trial tests whether specific nerve-gliding exercises can reduce long-lasting pain on the pinky side of your wrist. The exercises are designed to improve movement and decrease discomfort without surgery or medicine.
AnkaraAges 18 years+ - NCT07358936Recruiting
Corrective exercise and KT tape in young basketball players
This study tests whether corrective exercises and KT tape can help young basketball players. It's designed for boys ages 9–16 who play basketball and haven't had recent injuries or surgeries.
Istanbul, IstanbulAges 9–16 - NCT07357493Recruiting
Studying a new surgery for hand bone fractures
This trial tests a new way to fix certain broken hand bones (metacarpals) using a metal plate. It compares this method to other treatments to see which works better for healing and recovery.
Stockholm, Stockholm CountyAges 18 years+ - NCT07356999Recruiting
Seeing and scoliosis: a visual perception study in teens
This study looks at how scoliosis may affect how you see and process visual information. It compares teens with scoliosis to teens without it to better understand any differences.
LyonAges 11–18 - NCT05677152RecruitingPhase 2
Anti-bone-drug test to help shoulder tendon healing after surgery
This Phase 2 trial studies whether an anti-osteoporosis medicine (zoledronic acid) can improve healing after surgery for a chronic rotator cuff tear in the shoulder. If you qualify, you would also follow a specific 4-week physical therapy plan using a shoulder support pad.
ViennaAges 50–70 - NCT07356323Recruiting
Study on antibacterial drape for hip or knee replacement
This trial tests if a special antibacterial drape reduces contamination during hip or knee replacement surgery. The drape is placed over the skin to help prevent infection.
Fishers, IndianaAges 22 years+ - NCT07351968RecruitingPhase 1
Study of HRS-2129 for knee osteoarthritis pain
This trial tests an investigational drug, HRS-2129, for people with knee osteoarthritis who have moderate to severe pain. It aims to see if the drug is safe and effective at reducing pain.
Nanjing, JiangsuAges 18–80 - NCT07350252RecruitingPhase 4
Nerve blocks with local pain relief for knee replacement
This study tests if adding a nerve block to standard local pain relief medicine helps control pain better after knee replacement surgery. It may lead to less pain and faster recovery.
TrelleborgAges 18 years+ - NCT07348263Recruiting
Study on childhood eosinophilic fasciitis
This study looks at children diagnosed with eosinophilic fasciitis (a rare condition that causes skin swelling and stiffness) between 2000 and 2026. It aims to learn more about the disease and how it affects patients over time.
Birmingham, AlabamaAges Up to 18 years - NCT06367283RecruitingPhase 3
Metformin for treating hand osteoarthritis pain
This study tests whether metformin, a common diabetes medication, can reduce pain in hand osteoarthritis. You may be eligible if your hand pain is moderate to severe and you haven't taken metformin before.
Copenhagen, FrederiksbergAges 18 years+ - NCT07347561Recruiting
Comparing myoelectric and bionic prosthetic hands
This study compares two types of prosthetic hands: a myoelectric hand (controlled by muscle signals) and a bionic hand (with more advanced features). The goal is to see which one works better for people who already use a prosthetic arm with a semi-electronic elbow.
Ankara, KeçiörenAges 18–65 - NCT07344272Recruiting
Study on exercises for shoulder blade winging
This trial tests a type of physical therapy to see if it helps pull your shoulder blades flat against your back. It might be an option if your shoulder blades stick out (called winging) and you haven't had recent shoulder surgery or certain nerve problems.
ManisaAges 20–40 - NCT05828810Recruiting
Testing antiseptic skin cleaning during hip or knee revision surgery
This study checks whether an antiseptic method for cleaning the skin before surgery is safe and helpful for patients having a repeat (revision) hip or knee replacement. It may help reduce the risk of infection related to surgery.
Barrie, OntarioAges 18 years+ - NCT06918860Recruiting
Nail vs. replacement for bone metastases in upper thigh
This trial looks back at past patients to compare two types of surgery for broken or weak thigh bones caused by cancer that spread. It helps doctors understand which option—a metal nail or a joint replacement—works better.
Bologna, Emilia-RomagnaAges 18 years+ - NCT05685706Recruiting
Study of spine alignment after hip or knee replacement
This study looks at how the alignment of your spine relates to your walking and posture after hip or knee replacement surgery for wear-and-tear arthritis. It may help doctors better understand how to monitor recovery and long-term function.
Taichung, North DistrictAges Any age - NCT06903767Enrolling by invitation
Automated vs manual tool study for hip replacement
This trial tests whether an automated surgical tool is better than a manual one for putting in hip replacement parts. If you are having a planned first-time hip replacement and are over 18, you might be able to join.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07324434Enrolling by invitationPhase 1
Study of an oral tablet for healthy adults and those with high uric acid
This trial tests a new tablet (F-02-2-Na) to see if it's safe and how the body processes it. It's for healthy volunteers and people with high uric acid levels who may need long-term treatment.
Guangzhou, GuangdongAges 18–45 - NCT07340385Recruiting
Blood Flow Restriction Training Study for Healthy Adults
This study tests how your body responds to a special exercise technique where blood flow is partly restricted while you work out. It may help people build muscle more efficiently with lighter weights.
Afyonkarahisar, MerkezAges 18–40 - NCT07339397Recruiting
Joint stiffness in ICU patients on breathing machines
This trial studies how common joint stiffness becomes in ICU patients who are on a breathing machine and cannot move for at least 7 days. It may help doctors better prevent and treat this problem.
Elâzığ, ElaziğAges 18 years+ - NCT07338955Recruiting
Reliability study of upper limb disability questionnaire
This study is testing how well a questionnaire works for people with upper limb problems. It aims to understand if the survey reliably measures disability. You may be asked to fill out a form about your symptoms.
Karachi, SindhAges 18–45 - NCT07337642Recruiting
Comparing two types of hip replacement stems
This study compares two kinds of hip implant stems (one with a collar, one without) to see which works better for patients getting their first total hip replacement. If you are scheduled for a cement-free hip replacement due to arthritis, this trial may be a good fit.
Washington D.C., District of ColumbiaAges 18–99 - NCT06930027Enrolling by invitation
Low-oxygen training for ice hockey players
This study tests whether training in a low-oxygen environment (hypoxia) can boost strength and power in ice hockey players. Researchers want to see if it helps improve your explosive movements and muscle function.
Katowice, Silesian VoivodeshipAges 18–35 - NCT07338760Recruiting
Core stability exercises effect on balance in archers
This study looks at whether doing core (trunk) muscle exercises for a short time can help archers with their balance and how well they can use their upper body when shooting. It is for archers who are already in a licensed program.
Kağıthane, IstanbulAges Any age - NCT06935201Recruiting
Digital rehab program for spinal stenosis surgery recovery
This study tests a digital, person-centered rehab program to help people recovering from surgery for lumbar spinal stenosis become more physically active. It aims to see if an online program can improve recovery and quality of life after surgery.
StockholmAges 18 years+
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,841 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,937 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.