Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,841 recruiting studies in this area right now.
By phase
- Not applicable3,975
- Phase 2223
- Phase 4196
- Phase 1191
- Phase 3149
- Phase 1/Phase 274
- Phase 2/Phase 333
Top conditions
- Knee Osteoarthritis185
- Rheumatoid Arthritis142
- Fibromyalgia102
- Osteoporosis88
- Osteoarthritis74
- Osteoarthritis, Knee72
- Rheumatoid Arthritis (RA)64
- Shoulder Pain50
- Psoriatic Arthritis47
- Hip Osteoarthritis41
- Systemic Lupus Erythematosus41
- Duchenne Muscular Dystrophy39
- Chronic Pain38
- Degenerative Disc Disease38
- Total Knee Arthroplasty38
- Musculoskeletal Pain36
- Pain35
- Dermatomyositis31
Leading sponsors
- Riphah International University110
- Cairo University72
- Istituto Ortopedico Rizzoli71
- Assistance Publique - Hôpitaux de Paris37
- Foundation University Islamabad34
- Mayo Clinic29
- Massachusetts General Hospital27
- National Taiwan University Hospital25
- Chinese University of Hong Kong22
- Hacettepe University22
Where studies are running
- California210
- New York94
- Florida80
- Massachusetts76
- Arizona75
- Maryland73
- Texas65
- Alabama57
- Illinois54
- Pennsylvania50
Recruiting studies4,841 total
- NCT06672354Recruiting
Virtual reality vs. exercises for balance in older adults
This trial tests whether a fun virtual reality game (like a video game you do standing up) can improve balance and walking better than a set of simple exercises. It is for older adults who can still walk on their own but want to stay steady on their feet.
IslamabadAges 55 years+ - NCT07112807Recruiting
Shoulder blade exercise study: Sphere vs. Blade
This study compares two types of exercise (ShoulderSphere and Bodyblade) to improve shoulder blade movement. It is for people who have scapular dyskinesia but no current or recent shoulder pain.
AnkaraAges 18–25 - NCT05905146Recruiting
Personalized opioid plan to shorten treatment time
This trial tests whether a personalized medication plan can help patients with short-term, non-cancer muscle or joint pain need strong opioid medicine for a shorter time. It’s aimed at improving how long treatment lasts while still managing pain.
LilleAges 18 years+ - NCT06864780Recruiting
Posture exercises for forward head posture in device users
This trial tests if posture correction exercises can help fix forward head posture caused by heavy smartphone or laptop use. It is for people who spend at least 2-3 hours daily on their devices and have not had treatment for this condition before.
Malakand, KpkAges 18–40 - NCT06652659Recruiting
Risk factors for broken collarbone not healing properly
This study looks at why some broken collarbones in the middle section don't heal well. It follows patients treated at two hospitals to find patterns that might help prevent future healing problems.
Copenhagen NVAges 18 years+ - NCT05519007Recruiting
Tested no-rinse cleanser to prevent joint infections after surgery
This study compares a no-rinse cleaning solution used during primary joint replacement surgery versus the usual care. It looks at how many people still have a joint infection 90 days after surgery.
Manhasset, New YorkAges Any age - NCT07105189Recruiting
Study of wireless vital sign monitors after spinal surgery
This trial tests whether a wireless, wearable monitor can safely track your heart rate and other vital signs after complex spinal surgery, reducing the need for frequent nurse checks. If you are having extensive back surgery and stay in the hospital for at least 3 days, you may be eligible.
CopenhagenAges 18 years+ - NCT07360847Recruiting
Understanding recovery from rotator cuff shoulder pain with non-surgical care
This study looks at people with rotator cuff shoulder pain who are starting non-surgical treatments like physical therapy. It aims to understand which factors help people get better, so doctors can provide more personalized care.
LimerickAges 18 years+ - NCT06876350Recruiting
Wood cast vs. thermoplastic splint after thumb surgery
This trial compares two types of casts used after thumb joint replacement surgery to see which one works better for recovery. Participation lasts about 6 weeks.
Tampa, FloridaAges 18 years+ - NCT06563141Recruiting
Rehabilitation program for C-shaped scoliosis
This study tests a specific rehabilitation program for people with a C-shaped spine curve (scoliosis) that is mild to moderate (10–30 degrees). The program aims to improve posture and reduce the curve without surgery.
CairoAges 18–30 - NCT06563843Recruiting
Study of VRAS robot for knee replacement surgery
This study looks at how surgeons use the Velys Robot-Assisted Solution (VRAS) during total knee replacement. It aims to improve surgical processes and outcomes.
Nottingham, NG5 8RXAges 18–100 - NCT06563531Recruiting
Do compression stockings help after hip or knee replacement?
This trial looks at whether compression stockings are still needed for people who have a new hip or knee joint and are following a modern "fast-track" recovery program. It aims to find out if these stockings are necessary to prevent blood clots when people are up and moving quickly after surgery.
BrestAges 18 years+ - NCT03553186RecruitingPhase 3
Tranexamic acid to reduce bleeding in spine surgery
This Phase 3 trial tests whether tranexamic acid can reduce bleeding during major spine fusion surgery for adults with scoliosis or spine degeneration. It may help lessen blood loss and the need for transfusions, while monitoring safety.
New York, New YorkAges 18–80 - NCT06565377Recruiting
Pre-surgery program for knee replacement patients
This trial tests a program of exercise, education, and support to help you prepare for knee replacement surgery. It aims to improve your recovery and quality of life.
Geel, AntwerpenAges 18 years+ - NCT07093905Recruiting
Comparing two anesthetics for rotator cuff repair surgery
This study compares two types of anesthesia (numbing medicine) for rotator cuff repair surgery. It will help find which method works better for pain control and recovery.
MarseilleAges 18 years+ - NCT07094659RecruitingPhase 1/Phase 2
Fall prevention training for older adults
This trial tests if a specific type of physical training can help older adults who are at risk of falling. It is designed for people aged 60-90 who have had a fall in the past year or are otherwise considered high risk.
Chicago, IllinoisAges 60–90 - NCT06038331RecruitingPhase 2
Umbilical cord membrane for thumb arthritis pain
This trial tests a special umbilical cord membrane placed in the joint to treat arthritis of the thumb base (STT joint). It may be an option if you have pain and disability that haven't improved with other treatments.
BesançonAges 18–75 - NCT07092982Recruiting
Comparing two numbing methods for knee replacement surgery
This study compares two different numbing techniques to see which provides better pain control during and after total knee replacement. It may help find a way to reduce pain and improve recovery.
IstanbulAges 18–75 - NCT07080450Recruiting
Safety and performance of a rotator cuff repair device
This study collects information on how well a specific suture anchor system works for rotator cuff repair and how safe it is. It may help doctors understand its benefits for patients recovering from this shoulder surgery.
QuimperAges 18 years+ - NCT07068893Recruiting
Wrist dislocation surgery with internal brace technique
This study looks at a surgical technique using four anchors and an internal brace to treat a type of wrist dislocation (perilunate). It may be an option if you've already had surgery for this injury and don't have broken wrist bones.
Orlando, FloridaAges 18–88 - NCT07066709RecruitingPhase 2
Hip pain study after hip surgery
This study tests if a second hip surgery can help people who still have pain at least 6 months after their first hip surgery. It may help you if you have ongoing hip pain and haven't needed strong pain pills.
Madison, WisconsinAges 18–45 - NCT07064148Enrolling by invitation
Self-massage for better golf performance
This study tests if a self-massage technique, called self-myofascial release, can improve physical fitness and swing performance in male college golfers. It may help you understand how to use simple exercises to enhance your game.
Haikou, HainanAges 18–25 - NCT07056920Recruiting
Bone growth for lower jaw implants using a custom shell
This study tests whether a custom-made porous zirconia shell can help grow new bone in a narrow lower jaw so a dental implant can be placed. It might be a good option if you have a missing back tooth and need more jawbone for an implant.
Giza, Giza GovernorateAges 18 years+ - NCT06860867Recruiting
Nucleus replacement for single-level discogenic low back pain
This trial tests a new device called PerQdisc for people with chronic low back pain from a single damaged disc in the lower spine. The goal is to see if the device can safely replace the inner gel of the disc without major surgery.
Glendale, ArizonaAges 22–70
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,841 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,937 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.