Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,610 recruiting studies in this area right now.
By phase
- Not applicable3,771
- Phase 2215
- Phase 4199
- Phase 1182
- Phase 3139
- Phase 1/Phase 270
- Phase 2/Phase 334
Top conditions
- Knee Osteoarthritis171
- Rheumatoid Arthritis131
- Fibromyalgia105
- Osteoporosis82
- Osteoarthritis71
- Rheumatoid Arthritis (RA)68
- Osteoarthritis, Knee65
- Shoulder Pain48
- Hip Osteoarthritis43
- Psoriatic Arthritis40
- Degenerative Disc Disease39
- Chronic Pain38
- Total Knee Arthroplasty38
- Systemic Lupus Erythematosus37
- Duchenne Muscular Dystrophy36
- Musculoskeletal Pain35
- Osteoarthritis (OA) of the Knee32
- Pain32
Leading sponsors
- Riphah International University85
- Istituto Ortopedico Rizzoli69
- Cairo University66
- Assistance Publique - Hôpitaux de Paris36
- Foundation University Islamabad31
- Mayo Clinic28
- Massachusetts General Hospital25
- National Taiwan University Hospital25
- Hacettepe University23
- Tanta University22
Where studies are running
- California207
- New York87
- Florida82
- Maryland76
- Arizona72
- Massachusetts71
- Texas66
- Alabama60
- Illinois51
- Pennsylvania48
Recruiting studies4,610 total
- NCT07485530Recruiting
Testing ultrasound strain tracking for physical therapy
This trial tests whether a new ultrasound method (speckle tracking) can measure soft tissue movement and strain to help guide physical therapy. It is looking for three groups: male pitchers, people with a foot tendon problem needing surgery, and people who had ACL knee surgery.
TaipeiAges 18–65 - NCT07484594Recruiting
Trunk stabilization plus knee rehab for knee-spine syndrome
This trial tests whether adding trunk stabilization exercises to standard knee osteoarthritis rehab can improve outcomes for people with both knee pain and low back pain. It may help if you have moderate knee arthritis and have had back pain for at least 3 months.
Islamabad, ALAges 40–60 - NCT07488806Recruiting
Understanding Nemaline Myopathy Over Time (Spain)
This study follows people with nemaline myopathy over time to better understand how the disease progresses. It helps researchers learn more about the condition and plan future treatments.
BarcelonaAges Any age - NCT07489092Recruiting
Smartphone rehab app for ICU recovery
This study tests a smartphone app that guides you through exercises and recovery steps after leaving the ICU. You can join if you're currently in the hospital, can use your own phone, and are ready to start rehab.
SeoulAges 19 years+ - NCT07489001Recruiting
Comparing opioid-free to standard anesthesia for back surgery
This study compares two types of anesthesia for lower back surgery: one that uses opioids and one that does not. The goal is to see which approach controls pain better with fewer side effects.
Istanbul, MaltepeAges 18–75 - NCT07486843RecruitingPhase 4
Preventing joint damage in early psoriatic arthritis
This trial tests if a treatment can prevent joint damage in people recently diagnosed with psoriatic arthritis. It compares a standard medication (methotrexate) with or without a newer biologic drug (adalimumab) to see which is better at stopping the disease from causing lasting harm.
Hong KongAges 18 years+ - NCT07484516Recruiting
Eccentric exercises and muscle energy for tennis elbow
This trial tests whether combining eccentric exercises with muscle energy technique can help reduce pain and improve function in people with tennis elbow. It is for those who have had symptoms for more than a few weeks.
Karachi, SindhAges 20–50 - NCT07486869RecruitingPhase 2
Emapalumab study for MDA5-related lung disease
This trial tests if emapalumab can help people with a serious lung condition linked to MDA5 antibodies. It may be an option for those with worsening breathing despite other treatments.
Miami, FloridaAges 18 years+ - NCT07482332Recruiting
Core exercises for knee arthritis in women
This study tests if core stability exercises can reduce pain and improve function in women with knee osteoarthritis. It is designed for those who have not had recent physical therapy and can move their knees and hips freely.
SivasAges 45–65 - NCT07481461Recruiting
Knee alignment and biology in osteoarthritis
This study looks at how changes in knee alignment affect symptoms and joint biology in people with early knee osteoarthritis. It may help doctors understand how to better treat knee OA.
Leuven, Vlaams-BrabantAges 18 years+ - NCT07486609Enrolling by invitation
Comparing tests for jaw joint pain diagnosis
This study compares two different ways to diagnose jaw joint (TMJ) problems: a jaw-motion analyzer and an MRI. It aims to see which method is more accurate for people with ongoing face or jaw pain.
CairoAges 18–50 - NCT07484425Recruiting
Jump training at different heights for soccer players
This study tests how different heights of jumping exercises affect soccer players. If you are a healthy, active soccer player looking to improve your performance, this trial may be a good fit.
Lahore, Punjab ProvinceAges 18–30 - NCT07486505Recruiting
Mindfulness for pain after arm or leg fracture surgery
This study tests whether brief mindfulness sessions before and after surgery help people manage pain and anxiety while recovering from a broken arm or leg, and may reduce the need for strong painkillers (opioids). It aims to see if this approach is practical and helpful for patients.
Hamilton, OntarioAges 18 years+ - NCT07486193Recruiting
Nunchaku exercise for frozen shoulder relief
This study tests whether practicing Nunchaku (a traditional martial arts tool) can help people with frozen shoulder, particularly those in the thawing stage. It aims to improve shoulder movement and reduce pain.
Hong KongAges 45 years+ - NCT07484243Recruiting
Chinese and Western medicine for rheumatoid arthritis
This study combines traditional Chinese medicine with Western medicine to treat rheumatoid arthritis. It aims to see how well this approach works for people with hard-to-treat RA or RA-related lung disease.
ShanghaiAges 18 years+ - NCT07488039Recruiting
Labral repair for shoulder instability with minor bone loss
This trial tests a surgery to repair a torn shoulder socket rim (labrum) in people with recurrent shoulder dislocations and minor bone loss. It aims to restore shoulder stability and prevent future dislocations.
Cairo, Cairo GovernorateAges 16 years+ - NCT07487987Recruiting
Imagery and exercises for chronic neck pain
This trial tests whether imagining movements (motor imagery) and doing special neck exercises can help people with long-term neck pain. You may be eligible if your neck pain has lasted at least 3 months and is at least moderate, and you haven't had recent neck surgery or therapy.
Konya, KaratayAges 18–65 - NCT07481864Recruiting
Early mental exercise after shoulder tendon repair
This study tests if a gentle, early mental exercise program helps improve shoulder recovery after a specific type of rotator cuff repair. It might be a good fit if you had surgery on two front shoulder tendons and are otherwise healthy.
Istanbul, TurkeyAges 30–65 - NCT07489521RecruitingPhase 4
Arthrosamid vs. steroid for knee arthritis pain
This trial compares a new injection called Arthrosamid with a standard steroid injection to see which works better for knee arthritis pain over time. It may help you if you have knee arthritis and have not had recent injections or knee surgery.
Dublin, DublinAges 18–100 - NCT07484685Recruiting
Earlier implant placement after tooth preservation
This study tests if placing a dental implant sooner (about 6-8 weeks after tooth removal and socket preservation) works well with a specific implant type. It is for people who need to replace a single front tooth, canine, or premolar and have good bone and gum health.
Guayaquil, GuayasAges 18 years+ - NCT07484529Recruiting
Water vs land exercises for knee osteoarthritis
This study compares two types of physical therapy exercises — one done in water and one done on land — to see which is better for reducing pain and improving movement in people with knee osteoarthritis.
RawalpindiAges 40–65 - NCT07486349Recruiting
Comparing two numbing blocks for shoulder surgery
This study compares two types of numbing blocks used during shoulder surgery to see which one works better and safer. It may help you because the block can provide pain relief after surgery.
IstanbulAges 18–75 - NCT06709963Recruiting
Brain stimulation for older adults with chronic back or knee pain
This study tests a type of brain stimulation called intermittent theta burst stimulation to see if it can reduce pain and improve thinking in older adults with long-term back or knee pain. The treatment involves a non-invasive procedure that uses magnetic pulses to stimulate the brain.
Hong KongAges 60–85 - NCT06777160Recruiting
Predicting bone cement risks with AI
This study uses artificial intelligence to predict a rare but serious reaction called bone cement implantation syndrome during hip and knee replacement surgeries. It may help doctors better prepare and protect you.
ErzurumAges 18 years+
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,610 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,508 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.