Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,841 recruiting studies in this area right now.
By phase
- Not applicable3,975
- Phase 2223
- Phase 4196
- Phase 1191
- Phase 3149
- Phase 1/Phase 274
- Phase 2/Phase 333
Top conditions
- Knee Osteoarthritis185
- Rheumatoid Arthritis142
- Fibromyalgia102
- Osteoporosis88
- Osteoarthritis74
- Osteoarthritis, Knee72
- Rheumatoid Arthritis (RA)64
- Shoulder Pain50
- Psoriatic Arthritis47
- Hip Osteoarthritis41
- Systemic Lupus Erythematosus41
- Duchenne Muscular Dystrophy39
- Chronic Pain38
- Degenerative Disc Disease38
- Total Knee Arthroplasty38
- Musculoskeletal Pain36
- Pain35
- Dermatomyositis31
Leading sponsors
- Riphah International University110
- Cairo University72
- Istituto Ortopedico Rizzoli71
- Assistance Publique - Hôpitaux de Paris37
- Foundation University Islamabad34
- Mayo Clinic29
- Massachusetts General Hospital27
- National Taiwan University Hospital25
- Chinese University of Hong Kong22
- Hacettepe University22
Where studies are running
- California210
- New York94
- Florida80
- Massachusetts76
- Arizona75
- Maryland73
- Texas65
- Alabama57
- Illinois54
- Pennsylvania50
Recruiting studies4,841 total
- NCT07054437Recruiting
Assessing gross motor skills in preschoolers via video
This trial uses videos to evaluate how healthy preschool children develop gross motor skills like walking. It may help understand typical movement in kids ages 1 to 6.
TaoyuanAges 1–6 - NCT07052279Recruiting
Water burpee exercises for women after thyroid surgery
This trial tests if water-based burpee exercises can improve physical function in post-menopausal women who had their thyroid removed. It may help you move better and feel stronger.
CairoAges 50–54 - NCT07260630Enrolling by invitation
Hamstring tightness relief study
This trial tests different massage-type techniques to see which helps tight hamstrings best. If you are between 18 and 30 and have stiff hamstrings, this may help find a quick, drug-free solution.
Ankara, AnkaraAges 18–30 - NCT07319546Recruiting
Faster recovery after first knee replacement
This study tests a faster, more active recovery program for people having their first total knee replacement. It may help you get back to daily activities sooner after surgery.
Dali, YunnanAges 50–80 - NCT04242589RecruitingPhase 2
Radiation plus bone cement for painful spinal metastasis pain
This trial tests adding a bone-cement procedure (vertebroplasty) along with radiation to reduce pain from cancer that has spread to the spine. It is for adults with painful metastatic (spread) tumors in the middle or lower spine, without current spinal cord pressure.
Edmonton, AlbertaAges 18 years+ - NCT06847113Recruiting
Walking Speed Before and After Knee Replacement
This study follows people who are getting a knee replacement to see how their walking speed changes over time—both when they walk at their own pace and as fast as they can. It helps doctors understand recovery better.
OsloAges 55 years+ - NCT06861751Recruiting
Smartphone overuse and jaw proprioception in teens
This trial looks at how heavy smartphone use affects neck posture, neck muscle endurance, and jaw awareness in teenagers aged 17-19. It aims to understand if long-term phone use is linked to these physical changes.
Al MansurahAges 17–19 - NCT07036120Recruiting
How Inserts and Exercises Affect Bunions and Your Legs
This study looks at how wearing special shoe inserts or doing specific exercises can correct bunions and affect your legs. It may help if you have bunions on both feet and are between 18 and 45 years old.
Guangzhou, GuangdongAges 18–45 - NCT07222462Recruiting
Radiofrequency ablation for chronic low back pain
This study tests if radiofrequency ablation, a procedure that uses heat to block pain signals from the facet joints in your spine, can help people with long-term low back pain that hasn't improved with other treatments like physical therapy.
Atlanta, GeorgiaAges 18 years+ - NCT07028723Recruiting
Proprioception and ligament injury risk in pivoting sports
This study tests whether your sense of body position and movement affects your risk of knee or ankle ligament injuries while playing sports like rugby, soccer, or handball. Participating could help identify ways to prevent these injuries.
MontpellierAges 14–25 - NCT07027644Recruiting
Combined therapy for chronic neck pain relief
This trial tests whether combining a muscle-relaxation technique with cupping therapy is more effective than either alone for treating chronic neck pain caused by muscle knots in the upper trapezius. Participants must have had these knots for more than 6 months.
GizaAges 18–40 - NCT07024095Recruiting
Breathing muscle training after back surgery for osteoporosis
This study tests whether a simple breathing-muscle training program can help people recover better after vertebroplasty surgery for a broken back caused by osteoporosis. It aims to improve your breathing strength and overall function.
Kayseri, KocasinanAges 50 years+ - NCT07024407RecruitingPhase 1/Phase 2
Study of andecaliximab for preventing bone growth after spinal cord injury
This trial tests a drug called andecaliximab to see if it can stop abnormal bone growth (heterotopic ossification) that sometimes happens after a spinal cord injury. It is for people who are at high risk for this bone growth and aims to prevent it from forming.
Denver, ColoradoAges 18–89 - NCT07023146Enrolling by invitation
Power training for older adults: comparing different intensities
This study compares different power training intensities for older adults to see which is most effective. If you are 60 or older and not currently doing strength training, you may be eligible.
Porto Alegre, Rio Grande do SulAges 60 years+ - NCT07018219Recruiting
Finding the 7th neck bone by touch in neck pain patients
This trial looks at a simple way to find the 7th neck bone (cervical vertebra) by feeling it while you move your neck. It may help doctors better diagnose and treat neck pain.
ZagazigAges 18–60 - NCT06749431Enrolling by invitation
Meniscus transplant study: long-term outcomes
This study looks at how well meniscus transplants work over time — including how long the graft lasts and how it protects knee cartilage. It may be a good fit if you are getting your first or a repeat meniscus transplant, sometimes along with other knee repairs.
Plano, TexasAges 10–65 - NCT07217626RecruitingPhase 4
Nerve blocks before leg fracture surgery in older adults
This trial tests whether giving a nerve block (medicine to numb the leg) before surgery helps older adults recover better from a broken leg bone. If you are 50 or older and need surgery for a specific type of leg fracture, you may be eligible.
Baltimore, MarylandAges 50 years+ - NCT07015632Recruiting
Fall risk screening with sensors in Duchenne MD
This study uses a machine-learning tool (like a smart computer program) to help predict fall risk in people with Duchenne Muscular Dystrophy. It involves wearing sensors to track your movement and balance, which could help doctors create safer care plans.
Seoul, JongnoAges 10–30 - NCT07013695Recruiting
Virtual reality to reduce sedation in orthopedic surgery
This trial tests if watching virtual reality during regional anesthesia for planned arm or leg surgery can lower the need for calming medicine. It may help you feel more relaxed without as many drugs.
ÉvreuxAges 18 years+ - NCT06723639Recruiting
Restoring the torn Achilles tendon
This trial is testing a new way to repair a completely torn Achilles tendon. It uses MRI scans to make sure the repair is as good as possible, aiming for better healing and recovery.
Copenhagen, CapitalAges 18–67 - NCT07555067Enrolling by invitation
Robotic Knee Replacement Surgery Comparison
This trial compares two different robotic systems used during knee replacement surgery for knee arthritis (wear and tear). The study helps doctors understand which robotic system may provide better results.
Bydgoszcz, Kuyavian-Pomeranian VoivodeshipAges 18 years+ - NCT06751160Recruiting
Dry needling vs. soft tissue massage for tight hamstrings
This study compares two treatments—dry needling and soft tissue massage—to see which works better for relieving tight hamstring muscles in people with low back pain.
Lahore, Punjab ProvinceAges 20–40 - NCT06731972Recruiting
Mobile game app for thumb rehab
This study tests whether playing a mobile game can help people recover from thumb injuries, like fractures or tendinitis, by improving pain and hand function. It is for adults aged 18 to 65 who have thumb problems and can use a smartphone.
Kirşehi̇rAges 18–65 - NCT07006402Recruiting
Comparing two therapies for upper back stiffness
This study compares two gentle physical therapy techniques for improving movement in the upper back. It may help if you have stiffness or limited motion between your shoulder blades and are between 18–39 years old.
IslamabadAges 18–39
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,841 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,937 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.