Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,841 recruiting studies in this area right now.
By phase
- Not applicable3,975
- Phase 2223
- Phase 4196
- Phase 1191
- Phase 3149
- Phase 1/Phase 274
- Phase 2/Phase 333
Top conditions
- Knee Osteoarthritis185
- Rheumatoid Arthritis142
- Fibromyalgia102
- Osteoporosis88
- Osteoarthritis74
- Osteoarthritis, Knee72
- Rheumatoid Arthritis (RA)64
- Shoulder Pain50
- Psoriatic Arthritis47
- Hip Osteoarthritis41
- Systemic Lupus Erythematosus41
- Duchenne Muscular Dystrophy39
- Chronic Pain38
- Degenerative Disc Disease38
- Total Knee Arthroplasty38
- Musculoskeletal Pain36
- Pain35
- Dermatomyositis31
Leading sponsors
- Riphah International University110
- Cairo University72
- Istituto Ortopedico Rizzoli71
- Assistance Publique - Hôpitaux de Paris37
- Foundation University Islamabad34
- Mayo Clinic29
- Massachusetts General Hospital27
- National Taiwan University Hospital25
- Chinese University of Hong Kong22
- Hacettepe University22
Where studies are running
- California210
- New York94
- Florida80
- Massachusetts76
- Arizona75
- Maryland73
- Texas65
- Alabama57
- Illinois54
- Pennsylvania50
Recruiting studies4,841 total
- NCT06513208RecruitingPhase 4
Ketorolac for pain after lower back fusion surgery
This trial tests if a non-steroidal anti-inflammatory drug (NSAID) called ketorolac can help reduce pain after lower back fusion surgery. It is for people who are having elective surgery to fuse one or two bones in their lower back.
Towson, MarylandAges 18–85 - NCT07182461Recruiting
Taping and exercises for upper crossed syndrome
This study tests if wearing a special tape and doing corrective exercises can help with neck and shoulder posture and muscle balance. It might be a good option if you have poor posture called upper crossed syndrome.
Taichung, BeitunAges 20–35 - NCT06848660Recruiting
Neck brace study for stable fractures
This study tests if a neck brace (orthosis) works well for treating stable neck fractures without surgery. It may be an option if you have a recent, mild neck break and are healthy enough for non-surgical care.
GothenburgAges 18 years+ - NCT07464665Recruiting
Comparing two hip socket implants for first-time hip replacement
This trial compares two types of hip socket implants (dual-mobility cups vs. standard cups) during first-time hip replacement through the front of the hip. It aims to see which type may reduce the risk of dislocation after surgery.
BrugesAges 18 years+ - NCT07169474Recruiting
Thumb base joint replacement for arthritis
This trial tests a surgery that replaces the joint at the base of the thumb to treat arthritis pain. It may help if you have thumb arthritis that hasn't improved with nonsurgical treatments.
MontpellierAges 18 years+ - NCT07162168Recruiting
Using AI to measure bone age from abdominal CT scans
This study uses artificial intelligence to estimate bone age from standard abdominal CT scans. It may help researchers understand how bone age relates to health conditions without extra X-rays.
BeijingAges 18 years+ - NCT06817616Recruiting
Rotator cuff repair with stem cells for large shoulder tears
This trial tests whether adding umbilical cord stem cells to standard arthroscopic rotator cuff repair helps heal large or massive tears better. It may be an option if you have had shoulder pain for at least three months and other treatments haven't worked.
Seoul, KoreaAges 19 years+ - NCT05642013Recruiting
Short interval exchange surgery for infected hip or knee implants
This study compares how to replace an infected hip or knee implant using a two-step surgery with a shorter waiting time. It aims to reduce the time between surgeries while still safely treating the infection.
MontpellierAges 18 years+ - NCT04707001Recruiting
Tests urine problems after knee replacement surgery
This study looks at urinary retention (when you can’t pee normally) after elective total knee replacement. It may help doctors understand who is at risk and how to reduce this problem after surgery.
JyväskyläAges 18 years+ - NCT07141888Recruiting
Probiotic supplement for high uric acid
This study tests whether a probiotic food supplement can lower high uric acid levels, which often cause gout. It might help you if your uric acid is high but you haven't had a recent gout attack.
ÖrebroAges 18–80 - NCT07601906Recruiting
Blood Flow Exercise Therapy After Knee Replacement Surgery
This study tests whether special exercises that temporarily reduce blood flow to your leg can help you recover better after knee replacement surgery. It focuses on reducing pain and improving your ability to bend and straighten your knee.
Lahore, Punjab ProvinceAges 50–65 - NCT07133633RecruitingPhase 2
Tulisokibart for X-ray confirmed axial spondyloarthritis
This study tests a new medicine called Tulisokibart for people with a type of inflammatory arthritis that affects the spine and pelvic joints, specifically when X-rays show changes. The goal is to see if it can reduce symptoms like pain and stiffness.
Chandler, ArizonaAges 18–80 - NCT07309731Recruiting
Hot vs. cold radiofrequency for chronic low back pain from facet joints
This trial compares two types of radiofrequency treatment (cooled vs. thermal) to see which works better for chronic pain coming from the small joints in your lower back. It is for people who have had back pain for at least 3 months and haven't gotten enough relief from usual treatments like pain medicine or physical therapy.
Zagazig, ElsharqyaAges 30–70 - NCT04589819Enrolling by invitationPhase 4
Teriparatide for tibia stress fracture recovery for duty
This trial tests teriparatide, a medication that helps build bone, to see if it can speed recovery and help certain enlisted Army members return to training duty after a tibia bone injury. You may be asked to self-administer the medication while you recover and take part in study follow-ups.
Columbia, South CarolinaAges Any age - NCT07584915Enrolling by invitationPhase 4
Pain Relief Method Comparison for Knee Replacement Surgery
This study tests a new way to deliver pain medication during and after knee replacement surgery. Researchers compare injecting a long-acting numbing medicine (EXPAREL) directly into the knee joint versus spreading it through the surgical area, to see which method works better for pain control.
Los Angeles, CaliforniaAges 18 years+ - NCT05653544Recruiting
Study tracks symptoms in primary mitochondrial muscle conditions
This study observes people with primary mitochondrial muscle diseases over time to better understand how symptoms change. It may help improve future care by learning patterns of muscle weakness, fatigue, and related complications.
Madrid, MadridAges 16 years+ - NCT07131579Enrolling by invitation
Dexmedetomidine via IV for knee surgery pain
This trial tests adding a medicine called dexmedetomidine to the numbing IV used during knee surgery. It aims to see if it provides better pain relief after surgery under spinal anesthesia.
Al MansurahAges 18–60 - NCT07121283Enrolling by invitation
AI for reading children's bone age X-rays
This trial uses artificial intelligence to help doctors assess bone age in children from a single X-ray. It compares AI results with radiologists' readings.
Taipei, TaiwanAges Any age - NCT07273097Recruiting
Ankle muscle fatigue and walking in ankle instability
This trial studies how tired ankle muscles affect walking in people with chronic ankle instability. It compares their walking patterns to healthy people to understand if fatigue makes ankle issues worse.
LjubljanaAges 18–45 - NCT07127250Recruiting
Can walking sticks help people with spine imbalance walk more?
This study tests whether using walking sticks can help people with a forward-leaning spine (sagittal imbalance) walk more and feel better. If you are 50 or older, have trouble walking due to this spine condition, and don't already use walking sticks, you may be able to join.
ParisAges 50 years+ - NCT06230796Recruiting
Electrical stimulation cycling for stroke recovery
This trial tests whether using a special bike that delivers mild electrical pulses to your leg muscles can help improve walking after a stroke. If you have weakness on one side from a stroke that happened 3 to 12 months ago, this study may be a good fit for you.
Saint-Didier-au-Mont-d'Or, FranceAges 18 years+ - NCT06419452Enrolling by invitation
Resistance training for tennis serve speed and accuracy
This study tests different types of strength training to see which one improves how quickly and accurately young tennis players can serve. You'll train for several weeks and your serve will be measured before and after.
Lanzhou, GansuAges 16–20 - NCT07115316Recruiting
Hamstring exercises with physiotherapy for football players with mild ACL injury
This study tests if adding special hamstring exercises to standard physiotherapy can help young football players recover better after a mild ACL tear. It focuses on improving sports performance and quality of life with no surgery needed.
Ras al-Khaimah, Emirate of Ras Al KhaimahAges 19–25 - NCT07275983Recruiting
Knee replacement recovery: spinal vs. general anesthesia
This study looks at recovery after total knee replacement surgery. It compares people who had spinal anesthesia (numbing the lower body) to those who had general anesthesia (being fully asleep) to see which group recovers better.
StrasbourgAges 18 years+
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,841 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,937 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.