Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,840 recruiting studies in this area right now.
By phase
- Not applicable3,974
- Phase 2223
- Phase 4196
- Phase 1191
- Phase 3149
- Phase 1/Phase 274
- Phase 2/Phase 333
Top conditions
- Knee Osteoarthritis185
- Rheumatoid Arthritis142
- Fibromyalgia102
- Osteoporosis88
- Osteoarthritis74
- Osteoarthritis, Knee72
- Rheumatoid Arthritis (RA)64
- Shoulder Pain50
- Psoriatic Arthritis47
- Hip Osteoarthritis41
- Systemic Lupus Erythematosus41
- Duchenne Muscular Dystrophy39
- Chronic Pain38
- Degenerative Disc Disease38
- Total Knee Arthroplasty38
- Musculoskeletal Pain36
- Pain35
- Dermatomyositis31
Leading sponsors
- Riphah International University110
- Cairo University72
- Istituto Ortopedico Rizzoli71
- Assistance Publique - Hôpitaux de Paris37
- Foundation University Islamabad34
- Mayo Clinic29
- Massachusetts General Hospital27
- National Taiwan University Hospital25
- Chinese University of Hong Kong22
- Hacettepe University22
Where studies are running
- California210
- New York94
- Florida80
- Massachusetts76
- Arizona75
- Maryland73
- Texas65
- Alabama57
- Illinois54
- Pennsylvania50
Recruiting studies4,840 total
- NCT07003932Recruiting
Remote monitoring after knee replacement surgery
This trial tests a remote monitoring program for people having knee replacement surgery. It uses a smartphone app to track your recovery, so you can stay in touch with your care team without needing extra clinic visits.
Oslo, Please SelectAges 50 years+ - NCT07002983Recruiting
Shoulder exercises to help after mastectomy
This study is testing whether special exercises that retrain how you control your shoulder muscles can help reduce pain and improve movement after mastectomy. It is for women who had breast cancer surgery in the last few months and are now having shoulder problems.
GizaAges 40–55 - NCT07746284Enrolling by invitation
Understanding knee osteoarthritis through computer modeling
This study looks at how knee osteoarthritis pain works and aims to build a computer model to better understand it. By joining, you may help doctors improve future treatments for chronic knee pain.
Herndon, VirginiaAges 18–99 - NCT06368700Recruiting
Testing a new knee cartilage implant (HYALEX)
This study is testing a new implant called HYALEX to repair cartilage damage in the knee. It may help people with painful knee cartilage defects that haven't gotten better with other treatments like physical therapy or injections.
La Mesa, CaliforniaAges 22–70 - NCT07743684Recruiting
Jaw joint wash and meloxicam injection for jaw joint problems
This trial tests a treatment for people with jaw joint pain or clicking. It combines a jaw joint wash (arthrocentesis) with an injection of an anti-inflammatory medicine (meloxicam) to see if it helps relieve symptoms. This may be an option if other treatments like mouth splints haven't worked.
BaghdadAges 18 years+ - NCT07001449Recruiting
Pain education for chronic muscle or joint pain
This study tests a type of pain education that focuses on communication to help people with long-term muscle or joint pain. It aims to see if learning about pain in a new way can help reduce symptoms and improve quality of life.
Lamia, Central GreeceAges 18–65 - NCT06996028Recruiting
Lift and pedals for balance and movement in children with CP
This study tests if doing lifting and pedaling exercises helps children with cerebral palsy improve their balance and ability to move around. It may be a good fit if your child can walk without much help and follow simple instructions.
Lahore, Punjab ProvinceAges 6–12 - NCT07276061Recruiting
Outpatient vs. in-hospital knee replacement recovery study
This study compares recovery after total knee replacement when patients go home the same day versus staying overnight in the hospital. It aims to see if outpatient surgery leads to similar or better recovery.
StrasbourgAges 18 years+ - NCT06994546Recruiting
ArtiBest injection for knee osteoarthritis pain
This trial tests a new hyaluronic acid injection called ArtiBest for people with mild to moderate knee osteoarthritis who haven't gotten enough relief from other treatments like physical therapy or pain pills. It aims to see if the injection can reduce knee pain and improve function.
Kaohsiung CityAges 35–85 - NCT07278570Recruiting
Tracking muscle stiffness with MRI during hands-on therapy for low back pain
This study uses a special MRI scan to see if hands-on therapy (manual therapy) helps reduce muscle stiffness and pain in people with chronic low back pain. It aims to find a better way to measure how well this treatment works.
Rochester, MinnesotaAges 18 years+ - NCT06871735Recruiting
Collagen Material to Help Gum Heal After Bone Graft for Implants
This study tests a special collagen material used during bone graft surgery to help the gum close over the graft. It might help people who need extra bone before getting a dental implant.
Columbus, OhioAges 21–75 - NCT06988930Enrolling by invitation
Comparing two treatments for lateral patellar crush syndrome
This trial compares two treatments for lateral patellar crush syndrome: a type of knee surgery called lateral retinacular release versus specific exercises. The goal is to see which approach works better for reducing pain and improving function.
BeijingAges Any age - NCT06985459Recruiting
Splint for stiff finger joints after injury
This study tests whether a special splint called a 'relative motion orthosis' can help people regain movement in a stiff finger joint after an injury or surgery. If you have a recent finger joint problem and are willing to do hand therapy, this trial may help you recover better.
Bern, Canton of BernAges 18 years+ - NCT07266038Recruiting
Comparing two wire methods for children's elbow fracture
This trial is testing two ways of using small wires (K-wires) to hold a child's broken elbow bone in place after it's been set. The goal is to see which method keeps the bone correctly aligned as it heals.
Bahawalpur, Punjab ProvinceAges 2–13 - NCT06709963Recruiting
Brain stimulation for older adults with chronic back or knee pain
This study tests a type of brain stimulation called intermittent theta burst stimulation to see if it can reduce pain and improve thinking in older adults with long-term back or knee pain. The treatment involves a non-invasive procedure that uses magnetic pulses to stimulate the brain.
Hong KongAges 60–85 - NCT06975254Recruiting
Smartphone nursing support for hip fracture recovery
This study tests a special nursing program that uses a smartphone app to support people recovering from a hip fracture caused by fragile bones. It aims to improve recovery and prevent future fractures.
Yiwu, ZhejiangAges 18 years+ - NCT06969222Recruiting
Robotic knee replacement study with a special implant
This study tests a robot-assisted knee replacement using a new type of implant designed to move more like a natural knee. It may help people with arthritis or other knee joint problems who need a total knee replacement.
Larissa, ThessalyAges 18–95 - NCT06968052Recruiting
Feldenkrais method for forward head posture
This study tests whether the Feldenkrais method (gentle movement lessons) can improve forward head posture in people who sit at a desk for long hours. You may join if you are 18–65, have forward head posture, and spend at least 4 hours daily at a desk.
Istanbul, BuyukcekmeceAges 18–65 - NCT06877936Recruiting
Shoulder replacement imaging study
This study uses a special low-dose X-ray machine (EOS®) to take 3D pictures of your shoulder after reverse total shoulder replacement. The goal is to better understand how the replacement parts move and fit together. It may help improve future surgeries.
LyonAges 18 years+ - NCT06961578Recruiting
Comparing surgery and collar for odontoid fractures in older adults
This trial is comparing two treatments for a specific type of neck fracture (odontoid fracture) in people over 70: wearing a rigid neck collar versus having surgery. The goal is to see which approach leads to better recovery and quality of life.
Munich, BavariaAges 70 years+ - NCT06959680Recruiting
Kinesiotaping for posture and balance in hyperkyphosis
This study tests whether kinesiotaping (a special elastic tape placed on the back) can improve posture and balance in people with an exaggerated upper back curve (hyperkyphosis). It may help you if you have poor posture or back pain and meet the age and curve requirements.
IstanbulAges 18–45 - NCT05863741Recruiting
Knee surgery planning using a 3D next-step guidance system
This trial studies whether a NextAR system’s planning and gait (walking) analysis can improve how knee replacement surgery is done and how you walk afterward. It’s for adults with severe knee osteoarthritis who are eligible for total knee replacement.
FremantleAges 18 years+ - NCT06942689RecruitingPhase 4
Finding the best dose of numbing medicine for knee surgery pain
This trial tests different amounts of a long-lasting numbing medicine (liposomal bupivacaine) injected near the nerve in your thigh to see which volume works best for controlling pain after knee surgery. If you qualify, you may receive better pain relief and need fewer opioids.
Nanjing, JiangsuAges 18–85 - NCT05978024Recruiting
Predicting how sarcoma responds and side effects from limb radiotherapy
This study collects information to predict how soft tissue sarcoma in an arm or leg will respond to radiotherapy and what side effects may happen. It may help doctors improve planning and follow-up for people like you.
CambridgeAges 16 years+
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,840 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,943 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.