Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,837 recruiting studies in this area right now.
By phase
- Not applicable3,970
- Phase 2223
- Phase 4196
- Phase 1191
- Phase 3149
- Phase 1/Phase 275
- Phase 2/Phase 333
Top conditions
- Knee Osteoarthritis185
- Rheumatoid Arthritis142
- Fibromyalgia102
- Osteoporosis88
- Osteoarthritis74
- Osteoarthritis, Knee72
- Rheumatoid Arthritis (RA)65
- Shoulder Pain50
- Psoriatic Arthritis47
- Hip Osteoarthritis41
- Systemic Lupus Erythematosus41
- Duchenne Muscular Dystrophy39
- Degenerative Disc Disease38
- Total Knee Arthroplasty38
- Chronic Pain37
- Musculoskeletal Pain36
- Pain35
- Dermatomyositis31
Leading sponsors
- Riphah International University110
- Cairo University72
- Istituto Ortopedico Rizzoli71
- Assistance Publique - Hôpitaux de Paris37
- Foundation University Islamabad34
- Mayo Clinic29
- Massachusetts General Hospital27
- National Taiwan University Hospital25
- Chinese University of Hong Kong22
- Hacettepe University22
Where studies are running
- California211
- New York94
- Florida80
- Massachusetts76
- Arizona75
- Maryland73
- Texas65
- Alabama57
- Illinois54
- Pennsylvania50
Recruiting studies4,837 total
- NCT06714747Recruiting
Soft tissue prediction for jaw surgery
This trial tests a new way to predict how facial soft tissues will change after jaw surgery using advanced imaging. It may help people needing orthognathic surgery to understand the likely aesthetic outcome.
Bologna, Emilia-RomagnaAges 18 years+ - NCT07298629Recruiting
Testing smart shoes for collapsed foot arches
This trial tests whether smart shoes or insoles can help people with flat feet. If you have a collapsed arch and a foot posture score of 6 or higher, you may be able to join.
TaipeiAges 20–65 - NCT06710119Recruiting
Custom Brace for Foot and Ankle Injuries
This study tests whether a custom carbon fiber brace can help people with foot or ankle injuries walk with less pain and better balance. If you have an injury below your knee and need a special brace, this trial may be a good fit.
Iowa City, IowaAges 18–65 - NCT06707909RecruitingPhase 4
Vitamin K2 gel for bone healing after tooth extraction
This study tests if applying a vitamin K2 gel directly into the tooth socket after extraction can help rebuild healthy bone faster. It is for people who need to have a single-rooted lower tooth removed.
Cairo, Cairo GovernorateAges 18–80 - NCT06707870Recruiting
Neck exercises for chronic pain relief
This trial compares two different treatments for long-lasting neck pain: a special exercise that helps with neck posture (cervical retraction) and a gentle manual therapy technique (facet oscillatory mobilization). It aims to find which method is better at reducing pain and improving neck movement.
Peshawar, KPKAges 35–50 - NCT06706479Enrolling by invitation
Brain stimulation for balance in older adults with back pain
This study tests whether a gentle, non-invasive electrical brain stimulation technique (called high-definition tDCS) can improve balance in older adults with chronic low back pain. Participants receive either real or sham stimulation during balance training sessions.
Hong Kong, Hong KongAges 60–85 - NCT07547215Recruiting
TRAQ Minimally Invasive Sacroiliac Joint Fusion Study
This study tests a minimally invasive surgical procedure called TRAQ to treat chronic sacroiliac joint (SIJ) pain—a type of lower back and buttock pain. The procedure may help if you've had pain for at least 6 months that didn't improve with non-surgical treatments and have already benefited from diagnostic joint injections.
Tucson, ArizonaAges 21 years+ - NCT06704256Recruiting
Using neck muscle scans to predict frailty before ENT surgery
This study looks at neck CT scans to see if muscle size can help predict frailty in people having ear, nose, or throat surgery. It may help doctors better prepare for your recovery.
New York, New YorkAges 18 years+ - NCT06175884Recruiting
Communication skills for chronic muscle and joint pain
This trial tests how a physical therapist's communication style affects pain and function in people with long-term muscle or joint pain. Participants will fill out questionnaires and watch a video to see if better communication improves outcomes.
LamiaAges 18–65 - NCT06700694Recruiting
Helping ICU patients move early with technology
This trial tests a technology-assisted program to help patients in the intensive care unit (ICU) start moving earlier while on a breathing machine. It aims to improve recovery and reduce complications from being in bed for too long.
TaipeiAges 18 years+ - NCT06663644Recruiting
Muscle energy technique for short-term low back pain
This study will test whether a gentle hands-on technique called muscle energy can help relieve short-term lower back pain caused by poor posture. If you are an adult between 18 and 40 with new back pain and no other major health issues, this trial may be a good fit.
Gilgit, Gilgit-BaltistanAges 18–40 - NCT06699134Recruiting
Study on Hi-Fatigue G Bone Cement in Knee or Hip Replacement
This study looks at how well a specific bone cement (Hi-Fatigue G) works in people who have had a knee or hip replacement. It aims to help doctors understand if this cement is a good option for holding the artificial joint in place.
Weiden, BavariaAges 18 years+ - NCT06697860Recruiting
Shockwave vs. massage for chronic heel pain
This study compares two treatments for chronic heel pain (plantar fasciitis): radial shockwave therapy and Graston technique (a special scraping massage). It aims to see which works better to reduce pain and improve function in adults aged 20–45 who have had symptoms for more than 3 months.
Lahore, Punjab ProvinceAges 5 months–10 months - NCT06689761Enrolling by invitation
Collagen peptides and exercise: muscle strength study
This trial tests whether taking collagen peptides before exercise can improve how your muscles adapt to strength training. It could help you build muscle more effectively.
Vienna, State of ViennaAges 18–40 - NCT05929508Recruiting
Rebuilding leg strength after above-knee amputation
This study tests a new approach to improve walking ability and leg function after an above-knee (transfemoral) amputation. It may help by targeting muscle loss and supporting safer, stronger mobility over time.
Chicago, IllinoisAges 18 years+ - NCT06685120Recruiting
PRP and hyaluronic acid for knee osteoarthritis
This study tests a combination of platelet-rich plasma (PRP) and hyaluronic acid injections for knee osteoarthritis. It aims to see if these injections together can reduce pain and improve function better than standard treatments.
BolognaAges 40–75 - NCT07150143Recruiting
Massage and exercises for chronic neck pain
This trial tests whether adding a special type of massage (connective tissue massage) and other physical therapies to standard neck stabilization exercises helps people with long-term neck pain feel better.
Ataşehir, IstanbulAges 18–65 - NCT07348614RecruitingPhase 4
Knee manipulation: best numbing method for less pain
This study tests different numbing techniques to see which works best for pain during a knee manipulation procedure. It may help you have less pain and a smoother recovery.
Durham, North CarolinaAges 18–75 - NCT06679491Recruiting
How your menstrual cycle affects strength training
This study looks at how resistance training timed to your menstrual cycle affects muscle performance in women who have a natural cycle or take the pill.
Le Tampon, FranceAges 18 years+ - NCT07726459Recruiting
Balance and core stability in young football players
This study tests balance, core strength, and body awareness in amateur football players aged 13-19. It aims to see how these skills differ across age groups.
IstanbulAges 13–19 - NCT06673953Recruiting
Breathing training for heart surgery recovery with neck posture problems
This trial tests whether a breathing exercise device can improve heart and lung function in men who had heart bypass surgery at least 3 months ago and also have neck pain from poor posture. It may help you breathe better and feel stronger after surgery.
Giza, Giza GovernorateAges 45–55 - NCT07288060Enrolling by invitation
Hand therapy after wrist fracture surgery
This study tests two hand therapy methods to help improve wrist position sense after a broken wrist is fixed with metal plates and screws. It may help participants regain better control and function after surgery.
IstanbulAges 25–65 - NCT07611006Recruiting
Shoulder Stability Training With and Without Electrical Stimulation
This study tests whether adding electrical muscle stimulation to shoulder stability exercises helps people with loose, unstable shoulders feel better and move more reliably. You'll do exercises to strengthen the muscles that support your shoulder joint.
TaipeiAges 20–50 - NCT05936593Recruiting
Compare two knee implant positions during robotic knee replacement
This study compares how a knee implant’s components “fit” and move when placed in two different ways during robotic knee replacement. It uses special imaging to see which placement works best for stability and long-term performance.
Zoetermeer, South HollandAges 18–70
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,837 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,953 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.