Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,837 recruiting studies in this area right now.
By phase
- Not applicable3,970
- Phase 2223
- Phase 4196
- Phase 1191
- Phase 3149
- Phase 1/Phase 275
- Phase 2/Phase 333
Top conditions
- Knee Osteoarthritis185
- Rheumatoid Arthritis142
- Fibromyalgia102
- Osteoporosis88
- Osteoarthritis74
- Osteoarthritis, Knee72
- Rheumatoid Arthritis (RA)65
- Shoulder Pain50
- Psoriatic Arthritis47
- Hip Osteoarthritis41
- Systemic Lupus Erythematosus41
- Duchenne Muscular Dystrophy39
- Degenerative Disc Disease38
- Total Knee Arthroplasty38
- Chronic Pain37
- Musculoskeletal Pain36
- Pain35
- Dermatomyositis31
Leading sponsors
- Riphah International University110
- Cairo University72
- Istituto Ortopedico Rizzoli71
- Assistance Publique - Hôpitaux de Paris37
- Foundation University Islamabad34
- Mayo Clinic29
- Massachusetts General Hospital27
- National Taiwan University Hospital25
- Chinese University of Hong Kong22
- Hacettepe University22
Where studies are running
- California211
- New York94
- Florida80
- Massachusetts76
- Arizona75
- Maryland73
- Texas65
- Alabama57
- Illinois54
- Pennsylvania50
Recruiting studies4,837 total
- NCT06685575Enrolling by invitation
Comparing two types of back surgery for leg pain
This trial compares a newer, less invasive surgery (endoscopic foraminotomy) to a traditional back surgery for people with leg pain caused by a narrowed spine canal. The goal is to see which approach provides better relief and recovery.
Chon Buri, Changwat Chon BuriAges 30–80 - NCT06807866RecruitingPhase 4
Duloxetine for pain after hip replacement surgery
This trial tests if duloxetine, a medication that helps with nerve pain, can reduce pain after hip replacement surgery. It may help patients who are having a first-time total hip replacement.
Miami, FloridaAges 18 years+ - NCT06804265Recruiting
Better bacteria testing for joint implant infections
This study is testing a new, advanced lab test that can quickly identify exactly which bacteria are causing a joint implant infection. The goal is to help doctors choose the right antibiotics and improve treatment success.
BolognaAges 18 years+ - NCT07401758Recruiting
Shockwave therapy for knee tendon pain
This study tests whether a noninvasive treatment called shockwave therapy can help reduce pain and improve function in people with patellar tendinitis, a common overuse injury of the knee tendon. It may be a good option for you if you have moderate knee pain and are otherwise healthy.
Guangzhou, GuangdongAges 18–45 - NCT06801574Recruiting
Comparing pain relief methods for back surgery
This trial compares three different ways to manage pain during and after back surgery (lumbar fixation). The goal is to find which approach provides better pain relief and recovery.
ErzurumAges 18–65 - NCT07065266Enrolling by invitation
Pain survey for ACL knee surgery patients
This trial is testing a simplified pain questionnaire for people who are having ACL knee surgery. The goal is to see if this shorter questionnaire can effectively measure pain levels after surgery.
Redwood City, CaliforniaAges 18 years+ - NCT06151353Enrolling by invitation
Testing a new bone density scan in British women
This study tests a new type of bone density scan called REMS (Radiofrequency Echographic Multi-Spectrometry) to see how well it works in British women. If you are a woman over 20, you may be eligible to help researchers understand if this faster, radiation-free scan can replace traditional methods.
Daventry, NorthamptonshireAges 20 years+ - NCT07742397Recruiting
Leg strength and balance in adults over 65
This study looks at how differences in strength and function between your left and right legs might affect your risk of falling. If you join, you'll help researchers understand why some older adults fall and others don't, which could lead to better fall prevention.
Milan, MilanAges 65 years+ - NCT05649007Recruiting
Monitoring the Saphir hip stem after new hip replacement
This study watches how a specific hip replacement part (the Saphir stem) performs after primary hip surgery in everyday care. It helps doctors and manufacturers learn about safety and outcomes after the device is already in use.
ToulouseAges 18 years+ - NCT06780319Recruiting
Digital rehab after hip replacement surgery
This trial compares a digital (app-based) rehabilitation program with standard care after hip replacement surgery. If you have a smartphone and speak French, this study could help you recover from home.
MérignacAges 18–80 - NCT06744907RecruitingPhase 4
Betadine under skin during back fusion surgery
This study tests whether a small amount of Betadine placed under the skin during back fusion surgery can help prevent infection. It's for people having their first posterior spinal fusion.
Akron, OhioAges Up to 26 years - NCT06776887Recruiting
Virtual reality exercises for burn recovery on legs
This trial tests whether virtual reality exercises can help people with leg burns improve balance and reduce depression and anxiety. It is for people who had a large thermal burn on their lower body at least 3 months ago.
GizaAges 35–55 - NCT06771323RecruitingPhase 2
Adding valbenazine to botox for neck muscle spasms
This study tests if adding a daily pill (valbenazine) to regular botox injections can better reduce neck muscle spasms. It helps people whose botox works but may not be enough.
Richmond, VirginiaAges 18–75 - NCT06758115Recruiting
Brain and Muscle Study for Teens with Scoliosis
This study looks at how the brain and muscles work together in teens with spinal curves (scoliosis). It uses skin sensors and brain wave tests to understand muscle control, which may help improve treatments.
HangzhouAges 10–18 - NCT07280741RecruitingPhase 4
Shingles vaccine study for people with rheumatic diseases
This study tests the recombinant shingles vaccine in adults with autoimmune rheumatic diseases who are on certain mild medications. It aims to see if the vaccine is safe and effective for them.
São Paulo, São PauloAges 18 years+ - NCT07703332Recruiting
Stretching methods for arm pain from overuse
This study tests two different stretching techniques to see which one better relieves arm pain and improves movement in people with overuse injuries. It may help you if you have long-lasting discomfort from repetitive activities like typing or manual work.
Faisalabad, Punjab ProvinceAges 20–50 - NCT05757960Enrolling by invitation
Physiotherapy program for jaw pain in hEDS
This study tests a tailored physical therapy (physiotherapy) approach for jaw pain caused by temporomandibular disorder (TMD) in people with hypermobile Ehlers-Danlos syndrome (hEDS). It may help reduce jaw muscle and joint pain and improve function.
MünsterAges 18 years+ - NCT07624474Recruiting
Testing an elbow injury score for French-speaking children
This study is testing a French translation of a scoring system that measures how well children's elbows are working after injury. Researchers want to make sure this tool accurately reflects how kids actually function.
AmiensAges 4–17 - NCT07138066Recruiting
Smart crutch tips for guided weight-bearing after tibia fracture
This trial tests a smart crutch tip that helps guide how much weight you put on your leg while recovering from a broken shin bone. It is for people who have had surgery to fix the fracture and are learning to walk again with crutches.
Kyiv, Kyiv OblastAges 18–80 - NCT06732765Recruiting
Eloda with or without muscle energy for back pain relief
This trial tests whether adding a muscle relaxation technique to Eloda treatment helps people with lower back pain caused by a tight muscle near the hip. It aims to find a more effective way to reduce pain and improve movement.
Sialkot, Punjab ProvinceAges 18–45 - NCT06732687Recruiting
Exercise program to prevent injuries in school boys
This trial tests if a combination of bodyweight and jumping exercises can help prevent muscle and bone injuries in school-aged boys. It could be a good fit if your child is between 8 and 12 years old, has a normal weight, and hasn't had a recent injury.
Rawalpindi, Punjab ProvinceAges 8–12 - NCT06729437Recruiting
Transcranial brain stimulation for patellar tendon pain
This trial tests whether a gentle brain stimulation technique called transcranial direct current stimulation (tDCS) can improve knee function and reduce pain in people with long-term patellar tendinopathy (jumper's knee). It may help by calming pain signals in the brain.
Valencia, ValenciaAges 18–50 - NCT06723782RecruitingPhase 2
Wrapping hand tendons with amniotic membrane after release surgery
This study tests a new surgery to release a stiff hand tendon and wrap it with a special membrane made from amniotic tissue. The goal is to see if this helps the tendon glide better and prevents scar tissue from forming again.
LyonAges 18–65 - NCT05701592Recruiting
Testing two-bundle surgery for a torn knee ligament
This trial studies outcomes after a specific type of knee surgery for a torn ligament in the back of the knee. It may help people with a confirmed ligament tear who have pain and instability, by improving how well the knee works after reconstruction.
Bełchatów, Łódź VoivodeshipAges 18 years+
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,837 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,953 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.