Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 11,934 recruiting studies in this area right now.
By phase
- Not applicable9,337
- Phase 2764
- Phase 1555
- Phase 3514
- Phase 4340
- Phase 1/Phase 2299
- Phase 2/Phase 3125
Top conditions
- Stroke797
- Parkinson Disease395
- Alzheimer Disease337
- Multiple Sclerosis330
- Dementia224
- Epilepsy192
- Ischemic Stroke190
- Insomnia159
- Traumatic Brain Injury151
- Obstructive Sleep Apnea142
- Spinal Cord Injuries142
- Acute Ischemic Stroke139
- Sarcopenia135
- Mild Cognitive Impairment126
- Cerebral Palsy119
- Pain Management113
- Migraine107
- Fibromyalgia105
Leading sponsors
- Beijing Tiantan Hospital124
- Assistance Publique - Hôpitaux de Paris109
- Riphah International University105
- Mayo Clinic98
- VA Office of Research and Development92
- Xuanwu Hospital, Beijing89
- Hospices Civils de Lyon77
- Johns Hopkins University69
- University of Minnesota63
- Washington University School of Medicine63
Where studies are running
- California655
- Massachusetts304
- New York295
- Florida267
- Texas267
- Maryland248
- Arizona209
- Alabama205
- Illinois183
- Pennsylvania175
Recruiting studies11,934 total
- NCT06638944RecruitingPhase 2
Wearable feedback device for swallowing therapy in stroke or Parkinson's
This study tests a wearable device that provides feedback to help improve swallowing in people with stroke or Parkinson's disease. It may help make swallowing therapy more effective by showing real-time progress during exercises.
Champaign, IllinoisAges 50–90 - NCT01193075Recruiting
Tracking the course of charcot-marie-tooth disease over time
This study follows people with certain types of Charcot-Marie-Tooth disease (CMT), a genetic nerve disorder, over time to understand how the condition progresses. It also includes healthy volunteers as controls, and no experimental treatments are given.
Los Angeles, CaliforniaAges Any age - NCT07287436Recruiting
Watchman device to prevent stroke in atrial fibrillation
This trial tests a device called the WATCHMAN Elite, which is placed in a small pouch of the heart to close it and reduce stroke risk, potentially allowing patients to stop blood thinners. It is for people with atrial fibrillation who cannot or prefer not to take long-term blood thinners.
Jonesboro, ArkansasAges 18 years+ - NCT07879326Recruiting
Hearing screening for babies in Kenya
This study tests a newborn hearing screening program for babies in Kenya. It aims to find hearing problems early so babies can get the help they need.
NairobiAges 5 months–7 months - NCT05018871RecruitingPhase 1
Stem cell infusion for cerebral palsy
This trial tests whether a single infusion of stem cells from donated umbilical or placental tissue is safe for people with cerebral palsy. It may help reduce symptoms, but the main goal is to check safety.
Naples, FloridaAges Any age - NCT07878286Recruiting
How body awareness relates to fibromyalgia symptoms
This study looks at how well women with fibromyalgia notice internal body signals (like heartbeat or breathing) and whether that affects their pain and other symptoms. It may help doctors understand fibromyalgia better and improve future treatments.
IstanbulAges 18–65 - NCT07627750Recruiting
Low-dose muscle relaxant for spine surgery monitoring
This study tests whether a low dose of a muscle relaxant called rocuronium is safe and effective during spine surgery when doctors are monitoring the nerves. This may help patients who need spine surgery with nerve monitoring.
Hanoi, HanoiAges 18 years+ - NCT07095634Recruiting
Heart risk study for Crohn's and colitis patients
This study looks at heart health in people with Crohn's disease or ulcerative colitis. It aims to understand the risk of heart problems over 2 years.
San Donato Milanese, MilanAges 16 years+ - NCT07877480Recruiting
Predicting high-risk carotid plaque with imaging and biomechanics
This study looks at using scans and computer models to better predict which carotid artery plaques are dangerous, which may help guide safer treatment decisions.
MilanAges 18 years+ - NCT07139743RecruitingPhase 1
CAR T-cell therapy for progressive multiple sclerosis
This study tests a new treatment using a patient's own immune cells, modified to fight the immune system's attack on the nervous system. It aims to slow or stop the progression of multiple sclerosis when standard treatments have not worked.
Palo Alto, CaliforniaAges 18–60 - NCT01193088Recruiting
Genetics study for Charcot-Marie-Tooth disease
This study looks at genes linked to Charcot-Marie-Tooth disease (CMT), a condition that affects nerves in the arms and legs. It aims to find new causes and understand why symptoms vary. If you join, you may give a blood or saliva sample for genetic testing.
Los Angeles, CaliforniaAges Any age - NCT05474573Recruiting
Fluorescence-guided surgery for brain tumors
This study tests a surgery that uses a special light to make tumor tissue glow, helping doctors remove as much of the tumor as safely possible. It is for people newly diagnosed with certain aggressive brain tumors or tumors that have spread to the brain from elsewhere.
MoscowAges 18–80 - NCT07444580RecruitingPhase 1
Gene-silencing drug for prion disease
This study tests a new drug that targets the genetic material causing prion disease, aiming to slow or stop the disease. It's for people with symptoms or those at high genetic risk, and involves regular check-ups and spinal taps.
Boston, MassachusettsAges 18 years+ - NCT07877246Recruiting
Immune markers in brain-related illness
This study looks at blood and other samples from people with brain-related conditions that might involve inflammation or infection. It aims to find immune markers that could help understand these illnesses better.
Los Angeles, CaliforniaAges 1 month–100 years - NCT07626216Recruiting
Brain stimulation for muscle spasms
This study tests whether a non-invasive brain stimulation treatment called repetitive transcranial magnetic stimulation (rTMS) can help reduce abnormal muscle spasms in people with dystonia. It uses MRI to see how the brain changes with the treatment.
Manhasset, New YorkAges 18–80 - NCT07877948Recruiting
Combination therapy for diabetic nerve pain and foot ulcers
This study tests whether a treatment called Bionerv E+ helps with nerve pain and healing of foot ulcers in people with type 2 diabetes, compared with a standard vitamin B complex. If you have diabetes-related nerve damage and a foot ulcer that is not too severe, this study might help you understand if this new option works.
Cheras, Kuala LumpurAges 18 years+ - NCT07878156RecruitingPhase 3
Numbing medicine for children having brain tumor surgery
This study tests whether adding a numbing medicine to the standard pain block can reduce pain after brain surgery in children. It may help children feel more comfortable and recover more smoothly.
CairoAges Up to 18 years - NCT07878104Recruiting
Ketogenic diet for hard-to-control seizures in adults
This study looks at whether a special high-fat, low-carbohydrate diet can help reduce seizures in adults whose epilepsy has not improved with two or more medications. It is an observational study, meaning participants follow the diet as part of their regular care and the research team tracks their progress.
StockholmAges 18 years+ - NCT07877285Recruiting
Nutrition and monitoring to prevent confusion after gynecologic cancer surgery
This trial tests whether giving special nutrition before and possibly during surgery, along with careful brain monitoring during anesthesia, can reduce confusion (delirium) after surgery in older women with gynecologic cancer.
Elâzığ, ElâzığAges 65–80 - NCT06292494Recruiting
Focused ultrasound for drug-resistant epilepsy
This trial tests a treatment called focused ultrasound, which uses sound waves to target and help control seizures in people whose epilepsy has not improved with at least two medications. It may offer a new option for those with localized epilepsy.
TaipeiAges 18 years+ - NCT07602595Recruiting
Early-life health risks and chronic pain in teens and young adults
This study looks at how early health problems might affect pain that lasts a long time. If you had a muscle or joint surgery, or a rheumatic disease, before age 18, you might help us understand why some people get ongoing pain.
Cincinnati, OhioAges 14–26 - NCT07569263RecruitingPhase 1
CAR T cell therapy for brain metastases
This trial tests a new kind of cell therapy that uses your own immune cells (modified to attack cancer) to treat brain metastases. It may help people whose cancer has spread to the brain and hasn't responded to other treatments.
Gainesville, FloridaAges 18–80 - NCT07221669RecruitingPhase 3
Pre-symptomatic salanersen study for babies with SMA
This trial tests if the drug salanersen can help movement and is safe when given to babies diagnosed with spinal muscular atrophy before they show symptoms. It's for very young infants with specific genetic types of SMA.
Chicago, IllinoisAges birth–1 month - NCT00344331Recruiting
Testing blood and MRI markers for Niemann-Pick type C
This study measures biochemical (blood/biologic) markers and may use clinical evaluation and MRI to better understand Niemann-Pick disease type C. It could help improve how the condition is tracked and understood over time.
Bethesda, MarylandAges 1 day–120 years
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 11,934 recruiting neurology studies from the U.S. registry right now, out of 18,325 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.