Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,425 recruiting studies in this area right now.
By phase
- Not applicable9,762
- Phase 2784
- Phase 1574
- Phase 3535
- Phase 4342
- Phase 1/Phase 2305
- Phase 2/Phase 3123
Top conditions
- Stroke845
- Parkinson Disease426
- Multiple Sclerosis343
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California678
- Massachusetts300
- New York292
- Florida275
- Texas267
- Maryland245
- Arizona213
- Alabama211
- Illinois189
- Pennsylvania178
Recruiting studies12,423 total
- NCT04117672RecruitingPhase 2
Test antisecretory treatment in severe brain injury
This Phase 2 study tests an “antisecretory factor” treatment in people with severe traumatic brain injury. It may help by improving harmful processes after injury, but your eligibility depends on specific brain-injury severity and monitoring needs.
LundAges 10–70 - NCT04118790Recruiting
MRI study of brain microstructure after stroke
This study uses detailed brain MRI scans to learn how brain tissue changes after stroke or a TIA (a brief stroke-like event). It may help researchers better understand brain recovery and improve future care.
Copenhagen, København NVAges 18 years+ - NCT04121468RecruitingPhase 1/Phase 2
Metformin trial for vision nerve recovery in young people with MS
This study tests whether metformin can help “reset” damaged nerve cells in the brain and improve vision-related nerve problems in children and young adults with multiple sclerosis. Participants are assigned to metformin or a comparison treatment in a blinded (not everyone knows which) study.
Toronto, OntarioAges 10–25 - NCT04121780RecruitingPhase 2
Growth hormone treatment for retired NFL players with low hormone
This Phase 2 study tests whether growth hormone replacement helps retired professional football players who have been diagnosed with growth hormone deficiency. You may be considered if you meet age and health requirements and have the specific hormone diagnosis.
Dearborn, MichiganAges 18–76 - NCT04124848Recruiting
Sleep apnea study for Somali community adults
This study looks at obstructive sleep apnea—breathing pauses or poor breathing during sleep—in Somali community members. It aims to learn more about sleep apnea in this specific group, which can help guide better care.
Rochester, MinnesotaAges 18 years+ - NCT04126369Recruiting
Mindfulness program to improve quality of life in drug-resistant epilepsy
This trial tests whether a mindfulness training program can improve quality of life for people with drug-resistant epilepsy. It looks at whether learning mindfulness skills helps you cope day-to-day alongside your usual treatment.
GrenobleAges 18 years+ - NCT04128670Recruiting
Kinesio tape test for sore muscles after exercise
This study checks whether Kinesio tape changes how sore your muscles feel after workouts. You may help researchers learn if the tape reduces “delayed onset muscle soreness” after upper-body activity.
Indianapolis, IndianaAges 18–30 - NCT04129021Recruiting
Eye imaging test with fast detailed scans
This trial studies whether a new, very high-resolution and high-speed eye scan can be used for people with eye problems or for healthy volunteers. It may help doctors better “see” eye structures more clearly to guide care.
ParisAges 18 years+ - NCT04128709Recruiting
Home testing of bladder pressure with an external device
This study measures bladder pressure using a new external device that you use at home. It may help doctors understand how bladder function changes over time in people with neurogenic bladder.
Iowa City, IowaAges 1–99 - NCT04132362Recruiting
Personalized music program for people with dementia in care homes
This feasibility study tests whether a personalized music listening program in care homes is practical and acceptable. It may help people with dementia by using familiar, chosen music and collecting feedback on how they respond.
Harpenden, HertfordshireAges Any age - NCT04134754Recruiting
Testing how your brain responds to carbon dioxide in epilepsy
This study measures how sensitive your brain is to higher carbon dioxide levels to learn more about sudden unexpected death in epilepsy (SUDEP). You may be invited because you have epilepsy and are having evaluation at a specialized epilepsy unit or clinic.
Iowa City, IowaAges 18–99 - NCT04134923Recruiting
Brain PET scan study using a blood-flow and plaque tracer
This study uses PET/CT/MRI imaging to look for brain “imaging biomarkers” in people across the Alzheimer’s disease range. It may help researchers better understand how Alzheimer’s changes the brain over time and improve future treatments.
St Louis, MissouriAges 18 years+ - NCT04141020RecruitingPhase 2
Sirolimus study for unruptured brain aneurysms after surgery
This Phase 2 study tests whether sirolimus, a medicine that changes immune and growth signals, can change what’s happening inside the tissue of unruptured brain aneurysms after a procedure. Researchers hope these molecular changes may help understand how to improve aneurysm outcomes.
Miami, FloridaAges 18 years+ - NCT04141878Recruiting
Lifestyle program to help prevent dementia in adults with diabetes risk
This trial tests a structured lifestyle program (more activity and healthier eating) to help prevent or slow memory and thinking problems. It may be helpful if you’re older but not showing major memory impairment, and you can commit to weekly study activities for about 8 months.
Walnut Creek, CaliforniaAges 60 years+ - NCT04140903RecruitingPhase 4
Oral antibiotics after 14 days for bacterial brain abscess
This trial looks at whether continuing treatment for a bacterial brain abscess using partially oral antibiotics works as well as the usual approach. It may help people who have already had 14 days of antibiotic treatment and are stable enough to take medicines by mouth.
AalborgAges 18 years+ - NCT04142307Recruiting
Biofeedback training for infant eye shaking
This trial tests whether biofeedback-based training can improve control of eye shaking (nystagmus) in infants with idiopathic infantile nystagmus. If you can safely follow the training and testing steps, it may help the eyes learn more steady viewing over time.
Toronto, OntarioAges 5–17 - NCT04142866Recruiting
Brain stimulation plus language practice for chronic aphasia
This study tests whether mild brain stimulation (tDCS) combined with language exercises can improve communication after a stroke. It also includes healthy volunteers to help compare brain and language task results.
New York, New YorkAges 21–80 - NCT04144439RecruitingPhase 4
GABA treatment for ADHD and seizures in children with epilepsy
This trial studies whether adding GABA (a substance that affects brain signaling) can help children who have both epilepsy (seizures) and ADHD. If it works, it may reduce symptoms related to either seizures, ADHD, or both.
TantaAges 4–18 - NCT04145258RecruitingPhase 3
Stronger TB treatment for meningitis to reduce deaths
This trial tests if giving a stronger combination of TB drugs for meningitis can save more lives. It's for patients who have been diagnosed with tuberculosis meningitis and have not yet started more than 5 days of TB treatment.
AbidjanAges 15 years+ - NCT04144972Recruiting
Closed-loop deep brain stimulation for long-lasting nerve pain
This trial tests a “smart” deep brain stimulation device that senses your brain signals and adjusts treatment to reduce severe, long-lasting pain. It may help people whose pain has not improved with multiple pain medicines and surgery cannot fix the cause.
San Francisco, CaliforniaAges 22–80 - NCT04151082RecruitingPhase 1/Phase 2
Steroid therapy for late nerve damage after throat cancer radiation
This trial tests whether high-dose steroids (prednisone or methylprednisolone) can improve symptoms of nerve damage that may occur years after radiation treatment for oropharyngeal cancer. It includes a registry for tracking similar nerve issues in head and neck cancer survivors.
Houston, TexasAges 18 years+ - NCT04151472RecruitingPhase 3
Idebenone to prevent episodic migraine attacks
This trial tests idebenone, a preventive medicine, to see if it can reduce how often migraine attacks happen. It mainly focuses on people with episodic migraine who have regular attacks and are not already using other migraine prevention treatments.
Hangzhou, ZhejiangAges 18–65 - NCT04152551RecruitingPhase 4
Bisphosphonate use and hearing loss in type 1 osteogenesis imperfecta
This study looks at whether bisphosphonate treatment affects hearing loss in people with type 1 osteogenesis imperfecta. If you qualify, it may help researchers understand if treatment can protect hearing over time.
New York, New YorkAges 6–100 - NCT04155606Recruiting
Care plan for brain aneurysms after confirmation
This study looks at a comprehensive treatment approach for people who have a confirmed brain (intracranial) subarachnoid aneurysm. It may help by comparing or improving how aneurysms are managed to reduce future bleeding risk.
Edmonton, AlbertaAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,425 recruiting neurology studies from the U.S. registry right now, out of 19,436 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.