Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,407 recruiting studies in this area right now.
By phase
- Not applicable9,740
- Phase 2781
- Phase 1578
- Phase 3536
- Phase 4343
- Phase 1/Phase 2306
- Phase 2/Phase 3123
Top conditions
- Stroke841
- Parkinson Disease429
- Multiple Sclerosis345
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke201
- Epilepsy197
- Obstructive Sleep Apnea156
- Spinal Cord Injuries154
- Insomnia152
- Traumatic Brain Injury150
- Sarcopenia149
- Acute Ischemic Stroke137
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Migraine114
- Pain Management113
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic98
- Xuanwu Hospital, Beijing93
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California681
- Massachusetts299
- New York292
- Florida273
- Texas268
- Maryland246
- Arizona214
- Alabama210
- Illinois189
- Pennsylvania175
Recruiting studies12,405 total
- NCT06494540Recruiting
TDC treatment for advanced non-squamous lung cancer
This study is looking at how well a new treatment called TDC (which includes durvalumab and chemotherapy) works for people with a certain type of advanced lung cancer that has spread and has specific genetic features. It aims to see if this treatment is effective and safe in the real world, and it might be an option if you are starting this therapy anyway.
Bad HomburgAges 18–120 - NCT07548476Recruiting
Acupuncture and exercise for nerve pain from cancer treatment
This study tests whether adding acupuncture and exercise can help prevent or reduce nerve pain, numbness, or tingling caused by a cancer treatment called EV-Pembro (a drug combination for bladder cancer). It may help you stay active and feel better during treatment.
Boston, MassachusettsAges 18 years+ - NCT07775625Recruiting
Music therapy for anxiety in Alzheimer's disease
This study tests whether a specially designed music activity can help lower anxiety in people with Alzheimer's disease. If you or a loved one has Alzheimer's and feels anxious, this trial may offer a non-drug way to feel calmer.
Chicago, IllinoisAges 55 years+ - NCT07776444Recruiting
Measuring brain blood flow with light and MRI
This study uses a special light-based device and MRI to measure how blood vessels in the brain respond to changes. It may help researchers better understand blood flow in people with and without sickle cell disease.
St Louis, MissouriAges 6–70 - NCT07780461Recruiting
Testing a physical function assessment for Parkinson's disease
This study is testing a set of physical tests (called the Short Physical Performance Battery) to see if they are a good way to measure physical function in people with Parkinson's disease. By participating, you help doctors better understand how to assess mobility and balance in Parkinson's, which could improve future care.
Pontevedra, PontevedraAges 18 years+ - NCT07776275Recruiting
Headache study comparing neck pain patients with healthy people
This study looks at physical differences between people with cervicogenic headache (a headache that starts in the neck), people with chronic neck pain without headache, and healthy controls. By comparing these groups, researchers hope to better understand what causes the headache and which physical features are specific to it.
Istanbul, SefaköyAges 25–60 - NCT02479698RecruitingPhase 2
Immune cells for BK or JC virus infections
This trial tests a treatment using special immune cells (called cytotoxic T lymphocytes) to fight BK or JC virus infections in people with weakened immune systems, such as cancer patients or organ transplant recipients. It may help control the virus and reduce related complications.
Houston, TexasAges Any age - NCT07779486Recruiting
Intravenous magnesium for acute headache pain relief
This study compares two doses of intravenous (IV) magnesium to see which is more effective at relieving acute headache pain in the emergency department. It aims to provide a fast and effective treatment option for migraine, tension-type, or cluster headaches.
MonastirAges 18 years+ - NCT02703220RecruitingPhase 4
Sleep apnea treatment in older adults
This study tests whether certain medications can help older adults with mild to moderate sleep apnea breathe better during sleep. It aims to improve sleep quality and safety for elderly patients.
Detroit, MichiganAges 60–89 - NCT07705373Recruiting
Personalized music walking program for Parkinson disease
This study tests a digital music-based walking program that creates personalized playlists to help improve how you walk and make it feel more automatic. It may be helpful if you can walk for at least 10 minutes without help and are in early to middle stages of Parkinson's disease.
Boston, MassachusettsAges 40 years+ - NCT07779759Recruiting
Speech therapy intensity for children with speech sound disorders
This study compares two different levels of speech therapy (high-intensity versus low-intensity) to see which is more effective for children aged 4 to 12 who have difficulty making certain speech sounds correctly.
GhentAges 4–12 - NCT07774312Recruiting
Comparing tTIS treatment intervals to standard care for Parkinson's
This study compares different schedules of a non-invasive brain stimulation treatment (called tTIS) to standard medication for Parkinson's disease. It aims to find the best timing for tTIS to improve motor symptoms.
Shanghai, Shanghai MunicipalityAges 50–85 - NCT07515781Recruiting
VivaStent for Pulsatile Tinnitus Caused by Vein Narrowing
This study tests a stent (a small metal tube) placed in a narrowed vein in the brain to treat pulsatile tinnitus—a rhythmic ringing or whooshing sound in one ear that matches your heartbeat. The stent may improve blood flow and reduce or stop the sound.
ParisAges 18 years+ - NCT07779460Recruiting
Comparing two multiple sclerosis medicines in everyday practice
This study compares how well two medicines, Kesimpta and Ocrevus, work for people with multiple sclerosis when used in real life. It looks at patient records to see which treatment might be more effective.
East Hanover, New JerseyAges 18–100 - NCT07695246Recruiting
Sleep therapy with melatonin for older adults with insomnia
This study tests whether adding a melatonin supplement to a type of talk therapy for insomnia (called CBT-I) helps older adults sleep better. It aims to improve sleep quality and reduce insomnia symptoms.
Hong KongAges 60 years+ - NCT06466525RecruitingPhase 1
Testing LBT-3627 for safety in healthy adults and people with Parkinson's
This study tests an investigational drug called LBT-3627 to see if it is safe and how the body processes it. It includes healthy volunteers and people with Parkinson's disease, and may help determine if the drug could be a future treatment.
Melbourne, VictoriaAges 30–89 - NCT07778121Recruiting
Sleep apnea screening for people with type 2 diabetes
This study tests a home-based screening method for obstructive sleep apnea (a condition where breathing stops briefly during sleep) in people with type 2 diabetes. It aims to find undiagnosed cases, which could improve health and quality of life.
KøgeAges 18 years+ - NCT07778836RecruitingPhase 3
Study of daily injections for Friedreich's ataxia
This study tests an investigational drug given as a daily injection to see if it can improve walking and balance in people with Friedreich's ataxia.
Chicago, IllinoisAges 12–40 - NCT07417137Recruiting
Long-term study of Angelman syndrome
This study follows people with Angelman syndrome over time to learn more about the condition. It does not test any new treatments, but you need a parent or caregiver to come with you to all visits.
Lexington, MassachusettsAges 1 year+ - NCT07158905RecruitingPhase 1
Tau vaccine study for early Alzheimer's prevention
This study tests a vaccine that targets tau protein, which is linked to Alzheimer's disease. It is for older adults who have no memory problems yet but have biological signs of early Alzheimer's, to see if the vaccine can prevent or slow down the disease.
Boca Raton, FloridaAges 65–80 - NCT07040189Recruiting
AI nutritional plan for taste changes from chemo
This study tests an AI-created diet plan to help with taste problems caused by chemotherapy. It may help manage taste issues by suggesting recipes tailored to you.
Munich, BavariaAges 18 years+ - NCT06594627Recruiting
Smart pillow study for better sleep with snoring or sleep apnea
This study tests a smart pillow device to see if it can improve sleep quality for people over 50 who snore or have mild sleep apnea. It also looks at how the pillow affects sleep partners.
Indianapolis, IndianaAges 50 years+ - NCT07595068Recruiting
Ultrasound for Sleep and Heart Function Before Heart Surgery
This trial tests a new treatment using focused ultrasound to help regulate your nervous system and improve sleep quality before heart surgery. The goal is to help reduce anxiety and improve how well you sleep during the time leading up to and after your cardiology procedure.
Huangshi, HubeiAges 18–79 - NCT07210515RecruitingPhase 3
Testing Ambros Therapy for Early CRPS
This trial tests if an intravenous medicine called AMBTX-01 (neridronate) can help people with early-stage Complex Regional Pain Syndrome (CRPS) type 1. It focuses on those whose affected limb feels warm, looks red, and is swollen.
Phoenix, ArizonaAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,407 recruiting neurology studies from the U.S. registry right now, out of 19,231 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.