Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 11,934 recruiting studies in this area right now.
By phase
- Not applicable9,337
- Phase 2764
- Phase 1555
- Phase 3514
- Phase 4340
- Phase 1/Phase 2299
- Phase 2/Phase 3125
Top conditions
- Stroke797
- Parkinson Disease395
- Alzheimer Disease337
- Multiple Sclerosis330
- Dementia224
- Epilepsy192
- Ischemic Stroke190
- Insomnia159
- Traumatic Brain Injury151
- Obstructive Sleep Apnea142
- Spinal Cord Injuries142
- Acute Ischemic Stroke139
- Sarcopenia135
- Mild Cognitive Impairment126
- Cerebral Palsy119
- Pain Management113
- Migraine107
- Fibromyalgia105
Leading sponsors
- Beijing Tiantan Hospital124
- Assistance Publique - Hôpitaux de Paris109
- Riphah International University105
- Mayo Clinic98
- VA Office of Research and Development92
- Xuanwu Hospital, Beijing89
- Hospices Civils de Lyon77
- Johns Hopkins University69
- University of Minnesota63
- Washington University School of Medicine63
Where studies are running
- California655
- Massachusetts304
- New York295
- Florida267
- Texas267
- Maryland248
- Arizona209
- Alabama205
- Illinois183
- Pennsylvania175
Recruiting studies11,934 total
- NCT05619068Recruiting
Study tracking outcomes in Moyamoya disease
This study looks at how Moyamoya disease changes over time and what predicts outcomes. It uses approved brain imaging and, likely, thinking/memory tests to understand prognosis.
Beijing, Beijing MunicipalityAges 10–60 - NCT05294029Recruiting
Study of movement and aging in adults with neuromotor disability
This study looks at how neuro-related movement problems change as people age. It may help improve care plans for adults with neuromotor disabilities by learning what happens over time.
GarchesAges 18 years+ - NCT04594837Recruiting
Robotic ankle device therapy after stroke-related foot drop
This study tests a robotic ankle device to help improve walking in people after a stroke who still have foot drop (the foot doesn’t lift well). It may help strengthen or retrain walking patterns during recovery.
Baltimore, MarylandAges 18 years+ - NCT05663008Recruiting
Testing nerve-to-muscle signal changes to diagnose movement diseases
This study measures how nerves communicate with muscles, using recordings and gels. It aims to spot early, personalized signs of conditions like ALS and related diseases, and to improve diagnosis.
Dublin, LeinsterAges 18 years+ - NCT05672043Recruiting
Study genetic risks in children with malignant brain tumors
This study looks at genetic (DNA/molecular) features of malignant brain tumors in children. It may help doctors better understand tumor risk patterns and guide future treatment planning.
Beijing, Beijing MunicipalityAges birth–18 years - NCT05683093Recruiting
Follow-up study for adults after hypertensive pregnancy
This study follows young adults who previously joined the ALSPAC study to better understand long-term heart and metabolic health after a pregnancy affected by high blood pressure. You may be asked to return for visits and possibly an MRI, and your data may help researchers plan better long-term care.
Oxford, OxfordshireAges 30–40 - NCT05694039Recruiting
Track thinking changes in older adults with hearing loss
This study follows older adults who have age-related hearing loss to see whether wearing hearing aids helps protect thinking and memory over time. You may be included if your hearing loss is the type that hearing aids can usually improve and if your thinking test scores suggest mild cognitive difficulties.
Guangzhou, GuangdongAges 60–85 - NCT05088187Recruiting
Study of thinking and quality of life after thyroid surgery
This study looks at how thyroid surgery affects thinking (cognition) and day-to-day quality of life. It may help patients and doctors understand what to expect and how to support people after surgery.
StockholmAges 18 years+ - NCT05705778Recruiting
Blood biomarker study in children with amblyopia
This trial looks at a blood test (a “biomarker”) in children with amblyopia, a common vision development problem. It may help researchers understand what changes go along with treatment and vision improvement.
Guangzhou, GuangdongAges 3–12 - NCT00901602Recruiting
Study of invasive pneumococcal infections in Lebanon
This study collects laboratory samples from patients with invasive pneumococcal infections to learn about the germ and where it spreads. It may help doctors and public health teams track infection patterns and improve prevention and treatment planning.
BeirutAges 1 day+ - NCT03542734Recruiting
Imaging study for thinking and brain changes in older adults
This study looks at brain scans and eye/eye-nerve findings to understand why thinking can change with aging. It may help researchers connect eye and brain changes, which could guide future ways to prevent or detect dementia early.
HangzhouAges 40 years+ - NCT02883335Recruiting
MS registry for people living in Lorraine
This study is a registry that collects information from people who have multiple sclerosis (MS). It helps researchers better understand MS in the Lorraine region and may guide future care.
NancyAges Any age - NCT02910180Recruiting
Biobank study of genetic and metabolic data in brain blood vessel disease
This study collects genetic and other health information from people with brain blood vessel (cerebrovascular) problems. It aims to help researchers understand causes and patterns that could lead to better care in the future.
Los Angeles, CaliforniaAges 18 years+ - NCT05614193Recruiting
Deep imaging study for suspected stroke patients
This trial studies an advanced way to analyze CT or MRI scans for people who may have had a stroke or reduced blood flow to the brain. It aims to improve how scans are interpreted and shared for better care.
Beijing, Beijing MunicipalityAges 18–100 - NCT05272202RecruitingEarly Phase 1
Study brain signals after median nerve stimulation during anesthesia
This early-stage study checks how brain activity changes when the median nerve is gently stimulated while you’re under general anesthesia with propofol. It may help researchers better understand brain–nerve connections and improve how these signals are measured.
BrusselsAges 18–81 - NCT04436081RecruitingPhase 2
CBD oil without THC for agitation in Alzheimer’s dementia
This trial studies whether a THC-free CBD oil softgel can reduce agitation in people with Alzheimer’s-related dementia. It compares CBD to a control to see if it improves difficult behaviors and is safe over the study period.
Norfolk, VirginiaAges 50–90 - NCT05562024RecruitingPhase 1
Study drug for B7-H3 positive neuroblastoma after relapse
This Phase 1 study tests TAA06, an injection that targets a marker called B7-H3 on neuroblastoma tumor cells. It is for children who have neuroblastoma that has come back or did not respond to prior treatment, aiming to see whether the treatment is safe and can shrink tumors.
Jinan, ShandongAges 1 year+ - NCT05735444Recruiting
CPAP registry for sleep apnea in people with high blood pressure
This study keeps a record of people with obstructive sleep apnea (OSA) who also have high blood pressure, to better understand how CPAP is used and what outcomes happen. It may help your care team by contributing your information to a large multi-center study in China.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT05718622Recruiting
EECP for people with stable first stroke and blocked artery
This study looks at whether EECP (a non-surgical therapy that helps blood flow) improves outcomes in people who recently had their first ischemic stroke and have a narrowed or blocked artery. It also aims to predict who may benefit most based on health data.
Xi'an, ShaanxiAges 18–80 - NCT05752214Recruiting
Quality-of-life study for adults with vision problems
This study looks at how life quality changes or is measured in adults who have vision problems and are in specialized vision rehabilitation. You may be asked to answer questionnaires to help the research team understand your experience.
RomaAges 18 years+ - NCT05746715Recruiting
Study of people at risk for inherited CJD before symptoms
This study follows people who have a close family member with inherited Creutzfeldt-Jakob disease (CJD) to understand how the disease develops before any symptoms. It may involve genetic testing and safety-required procedures like brain scans and a spinal fluid test to learn about early changes.
Tel AvivAges 50 years+ - NCT05768048Recruiting
Study tracks SMA patients with specific gene changes
This study follows people with spinal muscular atrophy (SMA) who have a particular genetic change in the SMN1 gene. It compares long-term outcomes for those who do and do not receive disease-modifying treatments, to better understand what helps over time.
GenovaAges Any age - NCT05769699Recruiting
Blood test study for Parkinson’s stages
This study measures blood biomarkers (measurable substances in blood) in people with Parkinson’s at different stages. It may help doctors understand how Parkinson’s changes over time and could guide future testing or treatments.
RomaAges 18–80 - NCT05320263Recruiting
Thrombectomy timing: aspiration tube vs stent for basilar stroke
This trial compares two ways to remove a blockage in the brain’s basilar artery: suction (aspiration) versus a retriever stent. It may help doctors learn which approach works better for restoring blood flow in acute stroke patients.
BordeauxAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 11,934 recruiting neurology studies from the U.S. registry right now, out of 18,325 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.