Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,425 recruiting studies in this area right now.
By phase
- Not applicable9,762
- Phase 2784
- Phase 1574
- Phase 3535
- Phase 4342
- Phase 1/Phase 2305
- Phase 2/Phase 3123
Top conditions
- Stroke845
- Parkinson Disease426
- Multiple Sclerosis343
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California678
- Massachusetts300
- New York292
- Florida275
- Texas267
- Maryland245
- Arizona213
- Alabama211
- Illinois189
- Pennsylvania178
Recruiting studies12,423 total
- NCT04449068Recruiting
Tourette research using records from deep brain stimulation patients
This study is collecting information about people with severe Tourette syndrome who are not adequately helped by medication and may receive deep brain stimulation. It helps researchers understand outcomes and care patterns for this treatment over time using an observational database.
ParisAges 15 years+ - NCT04449666Recruiting
Brain scan and memory testing after bleeding from a brain aneurysm
This trial uses brain MRI scans and memory/brain-function tests in people who are recovering from a specific type of brain bleed (aneurysmal subarachnoid hemorrhage). It aims to understand how the brain’s memory area changes after the event and how that may relate to memory function during rehabilitation.
Hessisch OldendorfAges 18–70 - NCT04451278Recruiting
Brain scan study to predict outcomes after epilepsy surgery in kids
This trial uses resting-state brain MRI (a scan while you’re not doing a task) to help predict how well children with hard-to-treat epilepsy may do after surgery. If you qualify, you would help researchers see whether the scan can forecast prognosis.
Paris, PARISAges 6–18 - NCT04454892Recruiting
Study of ALS symptoms and disease course
This study watches people with ALS over time to better understand how symptoms change and what features show up. It may help future care and treatments by improving doctors’ understanding of ALS’s natural course.
BeijingAges Any age - NCT04457154Recruiting
Registry for teens and young adults with OSA who can’t use CPAP
This study collects information in a registry to help doctors understand outcomes for young people with moderate-to-severe obstructive sleep apnea who cannot use CPAP and may use an implantable breathing stimulation device. You might qualify if you’ve tried and couldn’t tolerate CPAP and you’re able/willing to get and use the device and return for follow-ups and sleep tests.
Aurora, ColoradoAges 18–21 - NCT04458688Recruiting
Ocrelizumab study for relapsing MS in African Americans and Caucasians
This study looks at how ocrelizumab works in people with relapsing-remitting multiple sclerosis (MS), and it specifically includes African American and Caucasian participants. Your neurologist may already be choosing ocrelizumab as the best standard treatment for you, and the study then follows you with medical visits and MRI scans.
Detroit, MichiganAges 18–60 - NCT04459806Recruiting
Study dose timing to improve care for brain injury
This trial studies how to time medication or treatment doses when a person has serious brain injury, using measurements from a pressure monitor in the skull. It may help doctors manage brain swelling and pressure more effectively.
Monza, MBAges 18–80 - NCT04460521RecruitingPhase 4
NAC pills and night splints for carpal tunnel without surgery
This trial tests whether N-acetylcysteine (NAC) along with wearing a night wrist splint can improve symptoms of mild to moderate carpal tunnel syndrome. It’s designed for people who want a non-surgical option.
Halifax, Nova ScotiaAges 18 years+ - NCT04460872RecruitingPhase 2
Testosterone plus walking training to support bones and muscles
This Phase 2 study tests whether testosterone therapy combined with walking training can improve bone and muscle health after a spinal cord injury. It aims to help men with low testosterone and walking problems by improving strength, body composition, and related health markers.
Gainesville, FloridaAges 18 years+ - NCT04463498Recruiting
Sleep school program for insomnia alongside mental health problems
This trial tests a group “sleep school” program to improve sleep when insomnia happens together with moderate to severe mental health symptoms. It may help you learn practical sleep strategies and improve sleep quality while you’re getting psychiatric care.
BergenAges 18–80 - NCT04461821Recruiting
Breath test to study disease in children
This study uses a special machine to analyze exhaled breath to learn about different illnesses in children and teens. It may help researchers find breathing “signals” that reflect conditions like breathing problems, nervous system issues, or new/worsening type 1 diabetes.
BaselAges Up to 22 years - NCT04461444Recruiting
Cohort study for Bardet-Biedl and Alström syndromes
This study follows people with Bardet-Biedl syndrome (BBS) or Alström syndrome (ALMS) to spot early vision, metabolic (body chemistry/energy), and kidney problems. You may be asked to have clinical checks over time to help researchers better understand how these complications develop.
StrasbourgAges 4 months+ - NCT04463316Recruiting
Clinic study for people with rare genetic conditions
This study is for people who have a rare syndrome or rare congenital condition and are seen at a rare-disease clinic. It aims to better understand these conditions and how care works in a team setting, which may help guide future treatment decisions.
Rotterdam, South HollandAges 18 years+ - NCT04468932Recruiting
TMS brain stimulation for progressive supranuclear palsy
This trial tests whether repeated non-invasive magnetic brain stimulation (TMS) can improve symptoms in people with progressive supranuclear palsy (PSP). It may help by targeting brain circuits involved in movement and balance.
Portland, OregonAges 40–85 - NCT04467437Recruiting
Noninvasive brain and nerve stimulation with walking therapy
This study tests whether a noninvasive electrical stimulation applied to the outside of the body, paired with physical therapy, can improve movement and walking for people with neurologic conditions. You may be asked to complete regular therapy sessions and simple movement tasks while the team measures your progress.
Seattle, WashingtonAges 4–70 - NCT04471740Recruiting
Study of hydrocephalus and sleep apnea
This study looks at people who may have normal-pressure hydrocephalus (fluid-related swelling in the brain) and also focuses on sleep apnea. It may help researchers understand whether treating or studying sleep issues could improve symptoms related to this condition.
Valencia, ValenciaAges 18 years+ - NCT04475510Recruiting
Stop blood-thinner therapy after PFO closure in younger stroke patients
This trial tests whether it’s safe to stop antithrombotic (blood-thinner) treatment after a successful hole-in-the-heart procedure (PFO closure) in people age 60 and under who had an unexplained stroke or TIA. It may help some people avoid long-term blood-thinner side effects if their risk stays low.
Québec, QuebecAges 18–60 - NCT04475640Recruiting
Genetic testing study for cancer patients in different ethnic groups
This study looks at cancer-related inherited gene changes using blood samples. It may help patients and doctors understand cancer risk and guide treatment planning, especially across different ethnic communities.
Scottsdale, ArizonaAges 18 years+ - NCT04477330Recruiting
Brain stimulation to improve walking after a stroke
This study tests whether a brain stimulation method (“cortical priming”) can improve walking after a stroke. It may help people with ongoing walking problems improve gait and leg control over a rehabilitation program.
Chicago, IllinoisAges 18 years+ - NCT04477785Recruiting
Study to track Parkinson’s signs using imaging, spinal fluid, and genes
This study is building a large, detailed group of people—some with Parkinson’s and some at higher risk—to understand early changes over time. It uses brain imaging (DaTscan SPECT), sometimes spinal fluid tests (lumbar puncture), and genetic information to help researchers better measure disease and develop future treatments.
Birmingham, AlabamaAges 30 years+ - NCT04478734RecruitingPhase 2
Thiamine plus biotin for Huntington’s disease symptoms
This Phase 2 study tests whether taking thiamine and biotin together can improve symptoms in people with Huntington’s disease. It looks especially at people with confirmed genetic Huntington’s disease and certain types of movement and/or mood symptoms.
San Sebastián, San SebastianAges 18 years+ - NCT04480853RecruitingPhase 4
Fingolimod start study for adults with relapsing MS
This study checks how safe and effective fingolimod is when adults with relapsing-remitting multiple sclerosis start it for the first time. It may help confirm whether this treatment works well and is tolerated in newly treated patients.
Kaohsiung CityAges 20–100 - NCT04487340Recruiting
Online database for people with acute stroke care
This study sets up an online database to track people who have had a stroke soon after it happens. The goal is to understand and improve how stroke care quality is evaluated.
Hangzhou, ZhejiangAges Any age - NCT04489199Recruiting
Join the Dijon stroke patient registry study
This study follows people who are already in the Dijon Stroke Registry and asks if they agree to participate. If you say yes, your information may be used to better understand stroke outcomes and care.
DijonAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,425 recruiting neurology studies from the U.S. registry right now, out of 19,436 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.