Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 11,952 recruiting studies in this area right now.
By phase
- Not applicable9,355
- Phase 2761
- Phase 1558
- Phase 3514
- Phase 4339
- Phase 1/Phase 2300
- Phase 2/Phase 3125
Top conditions
- Stroke798
- Parkinson Disease395
- Alzheimer Disease338
- Multiple Sclerosis328
- Dementia226
- Epilepsy193
- Ischemic Stroke190
- Insomnia159
- Traumatic Brain Injury151
- Obstructive Sleep Apnea142
- Spinal Cord Injuries142
- Acute Ischemic Stroke138
- Sarcopenia134
- Mild Cognitive Impairment127
- Cerebral Palsy119
- Pain Management116
- Migraine107
- Fibromyalgia104
Leading sponsors
- Beijing Tiantan Hospital124
- Assistance Publique - Hôpitaux de Paris109
- Riphah International University105
- Mayo Clinic98
- VA Office of Research and Development92
- Xuanwu Hospital, Beijing89
- Hospices Civils de Lyon77
- Johns Hopkins University69
- University of Minnesota63
- Washington University School of Medicine63
Where studies are running
- California661
- Massachusetts305
- New York295
- Florida272
- Texas266
- Maryland248
- Alabama207
- Arizona206
- Illinois181
- Pennsylvania177
Recruiting studies11,952 total
- NCT07474987Recruiting
Virtual reality test for brain injury diagnosis
This study uses a virtual reality device that shines light into your eyes to check how your pupils react. It aims to help diagnose and track traumatic brain injury in soldiers.
Tel Litwinsky, Tel Aviv (Gosh Dan)Ages 18–67 - NCT07478822RecruitingPhase 3
Botulinum toxin study for arm spasticity after stroke
This study tests a new botulinum toxin injection (YY001) for adults whose arm muscles are tight or stiff after a stroke. It looks at whether repeated treatments help with daily activities like washing and dressing.
BeijingAges 18–75 - NCT07476313Enrolling by invitation
Testing a new home sleep system for moderate to severe sleep apnea
This study tests a home sleep testing system called SleepView+ in people who have already been scheduled for an overnight sleep lab study. If you have moderate to severe obstructive sleep apnea, this device might offer a more convenient way to monitor your sleep at home.
Redwood City, CaliforniaAges 12 years+ - NCT07477691RecruitingPhase 4
Immune therapy during Palynziq treatment for PKU
This study tests whether combining a drug called methotrexate with Palynziq (a treatment for PKU) can help control immune responses and improve treatment outcomes. It may be an option for adults with PKU who have never used Palynziq or who have not reached target blood levels after at least 24 weeks.
Los Angeles, CaliforniaAges 18–65 - NCT07474935Recruiting
Real-world stroke treatment device registry
This trial collects information about the use of a specific stroke treatment device in real-world medical practice. It helps researchers see how well this device works for a wide range of patients, not just those in strict study conditions.
BrestAges Any age - NCT07478926Recruiting
Testing a skin device to check shunt flow
This study tests a new, noninvasive device placed on the skin over your shunt to see if it can detect when the shunt is open or closed. It may help doctors quickly check if the shunt is working without using X-rays or other procedures.
Peoria, IllinoisAges Any age - NCT07472023Enrolling by invitationEarly Phase 1
Stem cell therapy for hearing loss and tinnitus
This trial tests a regenerative stem cell treatment for people with hearing loss, tinnitus, or inner ear injury. It aims to see if the therapy can improve hearing or reduce symptoms.
New York, New YorkAges Any age - NCT07477639RecruitingPhase 1/Phase 2
Testing TRX319 for worsening multiple sclerosis
This trial tests a new treatment called TRX319 for people with progressive multiple sclerosis (MS) that has been getting worse. The study wants to see if this treatment can help slow down disability progression.
La Jolla, CaliforniaAges 18–65 - NCT07472491RecruitingPhase 2/Phase 3
Contrast MRI study for brain, spine, and body cancers
This trial tests a new contrast agent called mangaciclanol for MRI scans of the central nervous system (brain and spine) or body areas like the chest, belly, pelvis, and muscles. You may join if you have known or suspected tumors that need an MRI with contrast, and you're healthy enough to have two contrast MRIs within a short time.
Rochester, MinnesotaAges 18 years+ - NCT06758271Recruiting
Long-term study of avacopan for vasculitis
This study looks at the long-term safety and effectiveness of avacopan in people with certain types of vasculitis (GPA or MPA). It may help doctors understand how well the medicine works over time.
Multiple LocationsAges Any age - NCT06779578Recruiting
Comparing two types of radiofrequency for trigeminal neuralgia
This study compares two treatments (bipolar vs monopolar pulsed radiofrequency) for people with trigeminal neuralgia that hasn't improved with medication. It aims to see which method provides better pain relief.
AlexandriaAges Any age - NCT07476092Recruiting
Digital games for thinking and visual skills
This study tests whether playing specially designed digital games can improve visual and thinking skills in young adults with mild to moderate intellectual disabilities. It is run by Koç University and takes place at EÇADEM, a center that supports people with special needs.
Istanbul, TürkiyeAges 18–35 - NCT07475611Enrolling by invitation
Screen-based rehab for visual neglect after stroke
This study tests whether an interactive screen helps people with left-sided neglect after a stroke. It includes adults who had a right-sided stroke and have trouble paying attention to the left side of their world.
Buenos Aires, EscobarAges 18–88 - NCT07475377Recruiting
Meal timing and brain health in multiple sclerosis
This study looks at whether changing when you eat during the day can improve brain health for people with multiple sclerosis. It involves following a specific eating schedule and using a smartphone to track your meals.
Birmingham, AlabamaAges 18–64 - NCT07477509Recruiting
Northwestern neuromuscular disease tissue and blood bank
This study collects tissue and blood samples from people with nerve or muscle disorders to help researchers learn more about these conditions. The goal is to build a bank of samples for future studies.
Chicago, IllinoisAges 18 years+ - NCT07477730Recruiting
Pain Relief Options for Knee Replacement Surgery
This study compares two ways to manage pain after knee replacement surgery: local numbing medicine injected into the knee versus numbing several nerves in the leg. The goal is to find which method provides better pain control and recovery.
Toulouse, Haute-GaronneAges 18 years+ - NCT07477613Recruiting
Brain implant for arm recovery after stroke
This trial tests a brain-computer interface (a device implanted in the brain) to help people who have had a stroke regain arm movement. It may help if you have a single stroke that happened 6 to 18 months ago and still have trouble using your arm.
GrenobleAges 18–70 - NCT07472803Recruiting
Body composition study in early breast cancer patients
This study looks at how body composition (muscle and fat) changes over time in people with early-stage breast cancer. It aims to better understand the effects of cancer treatment on the body.
New Taipei City, Xindian DistAges 18 years+ - NCT07473505Recruiting
Nerve block for PTSD in special operations veterans
This study tests if a specific nerve block (cervical sympathetic block) can help reduce trauma-related symptoms in Special Operations veterans with PTSD. The goal is to see if this treatment is safe and can improve how you feel.
Strongsville, OhioAges 18 years+ - NCT07476781Recruiting
Liquid biopsy study for solid tumours and brain tumours
This study collects samples of spinal fluid and blood from people with solid tumours that have spread to the brain or spine, or who have primary brain tumours. The goal is see if these samples can help doctors detect and monitor these cancers more easily.
Toronto, OntarioAges 18 years+ - NCT07476365Recruiting
Finding new markers for early CMT1A disease
This study looks for new markers of early Charcot-Marie-Tooth 1A (CMT1A) disease using blood tests and special MRI scans. It aims to help understand how the disease progresses and may lead to better treatments.
GöttingenAges 10–30 - NCT07477483Recruiting
Manual therapy for tension headaches in menopausal women
This study tests if manual therapy (gentle hands-on techniques) can help reduce tension-type headaches in women going through menopause or premenopause. It involves tracking your headache symptoms and receiving treatment over several sessions.
Konya, KonyaAges 45–65 - NCT07476469Recruiting
Nerve stimulation for anhedonia and anxiety
This study tests whether a gentle nerve stimulation device (tVNS) placed on your ear can help reduce symptoms of anhedonia (loss of pleasure) and anxiety. You will also have brain scans (MRI) to see how the treatment affects your brain.
BonnAges 18–40 - NCT07472101Recruiting
Balance and cognitive exercises at home for older adults
This study tests whether home-based balance and thinking exercises done via video calls can improve balance, reduce fall risk, and boost brain function and sleep quality in older adults.
Zonguldak, KozluAges 65–74
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 11,952 recruiting neurology studies from the U.S. registry right now, out of 18,491 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.