Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,425 recruiting studies in this area right now.
By phase
- Not applicable9,762
- Phase 2784
- Phase 1574
- Phase 3535
- Phase 4342
- Phase 1/Phase 2305
- Phase 2/Phase 3123
Top conditions
- Stroke845
- Parkinson Disease426
- Multiple Sclerosis343
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California678
- Massachusetts300
- New York292
- Florida275
- Texas267
- Maryland245
- Arizona213
- Alabama211
- Illinois189
- Pennsylvania178
Recruiting studies12,423 total
- NCT04490161Recruiting
Preventing blood-vessel spasm after aneurysm brain bleeding
This trial studies a spinal fluid (CSF) treatment to help prevent dangerous blood-vessel tightening (vasospasm) after a type of brain bleed caused by an aneurysm. If you qualify, the goal is to reduce complications soon after aneurysm repair.
Innsbruck, TyrolAges 18–90 - NCT04492345Recruiting
Back muscle training for posture problems in Parkinson’s
This trial tests a special way to strengthen the back muscles to improve posture problems in people with Parkinson’s (or similar conditions). It may help reduce postural deformities and improve movement comfort while your Parkinson’s treatment stays steady.
Le LamentinAges 18–85 - NCT04490317Recruiting
Study follows people with carbon monoxide poisoning in Korea
This study looks at people who have been sickened by carbon monoxide (CO) from an accident or exposure. It aims to better understand what happens over time, which could help improve care and outcomes in the future.
Wŏnju, Gangwon-doAges Any age - NCT04493996Recruiting
Cognitive training before heart surgery to protect memory
This trial tests whether brain-focused cognitive training before elective heart surgery can help reduce memory and thinking problems afterward. If you qualify, you may do language-based thinking exercises and complete short brain tests around the time of surgery.
Bad NauheimAges 18 years+ - NCT04493372Recruiting
Testing how well nerves control the heart after spinal cord injury
This study looks at how well the body’s automatic nerve functions (like heart and blood pressure control) work after a traumatic spinal cord injury. The goal is to better understand preserved nerve function and autonomic (automatic body) control, which could help guide future treatments.
Rochester, MinnesotaAges 18–50 - NCT04496609Recruiting
Testing a spinal stimulation treatment for incomplete spinal cord injury
This trial studies whether a spinal cord stimulation approach plus rehab can improve function and safety in people with an incomplete spinal cord injury who cannot walk. It may help people by supporting rehabilitation over time, but it requires surgery and specific health and imaging conditions.
GarchesAges 18–65 - NCT04496973Recruiting
Parkinson’s disease research registry for adults
This registry asks people with Parkinson’s disease to join a research program at the University of Delaware. Being in the registry may help you get invited to investigator-led studies that could improve understanding or treatment of Parkinson’s.
Newark, DelawareAges 21–100 - NCT04499755RecruitingPhase 3
Nucleo CMP Forte for moderate to severe brain injury in children
This trial studies whether a supplement called Nucleo CMP Forte can improve outcomes after a moderate or severe traumatic brain injury in children. It may help families see if adding this treatment makes recovery better and safer.
TantaAges Up to 18 years - NCT04500847RecruitingPhase 1
Testing repurposed HIV-like drugs for early Alzheimer’s symptoms
This Phase 1 study tests whether an existing type of anti-viral medicine (nucleoside reverse transcriptase inhibitors) can help people with early Alzheimer’s disease. It also focuses on safety and proper dosing while measuring brain-related changes and memory-related symptoms.
Los Angeles, CaliforniaAges 50–85 - NCT04501081Recruiting
Studying how inherited hearing loss changes over time
This study follows people and families with autosomal dominant inherited hearing loss to better understand how it progresses. It may help researchers learn what to expect over time and guide future treatment planning.
Bethesda, MarylandAges 3–99 - NCT04501705Recruiting
Apatinib for adults with recurring atypical or malignant meningioma
This trial tests whether apatinib can shrink or control recurring atypical/malignant meningioma that has come back after surgery and radiation. It focuses on adults with measurable regrowth on MRI and good overall health to safely take an oral medicine.
Beijing, Beijing MunicipalityAges 18–70 - NCT04502225Recruiting
Trial of bed head elevation for high blood pressure
This study checks whether raising the head of the bed lowers blood pressure while you’re lying down in people with autonomic failure. It may help find a simple positioning change to reduce risks from high lying blood pressure.
Nashville, TennesseeAges 18–85 - NCT04502719Recruiting
Testing nutrition screening in people with liver cirrhosis
This study compares different ways of checking nutrition problems in people with liver cirrhosis. It may help doctors choose the best screening tool to spot risk earlier and guide care.
Barcelona, CataloniaAges 18–100 - NCT04507178RecruitingPhase 2
Nadroparine to improve recovery after bleeding in the brain
This study tests whether nadroparine (a blood-thinning medicine) can improve outcomes after a type of brain bleed called subarachnoid hemorrhage. It focuses on people who have had a brain aneurysm treated with a procedure soon after the bleed.
AmsterdamAges 18 years+ - NCT04510051RecruitingPhase 1
CAR T cell therapy for IL13Rα2 positive pediatric brain tumors
This Phase 1 study tests a type of immune therapy (CAR T cells) for children with brain tumors that come back or do not respond to standard treatment. The cells are given after chemotherapy that temporarily lowers the body’s immune system, which may help the CAR T cells work better.
Duarte, CaliforniaAges 4–25 - NCT04506853Recruiting
Cochlear implant study for one-sided severe hearing loss
This trial is studying whether a cochlear implant can help people who have very poor hearing in one ear but normal or mild hearing loss in the other ear. It uses hearing tests and speech understanding to see who may benefit and how well the device works.
Chicago, IllinoisAges 5 years+ - NCT04507997Recruiting
Study of the natural course of Angelman syndrome
This study follows people with Angelman syndrome to understand how their symptoms and development change over time. It may help researchers better describe the condition and support future treatments.
Los Angeles, CaliforniaAges Any age - NCT04510363Recruiting
Ultrasound checks after cardiac arrest to predict recovery
This study uses ultrasound pictures of the eye and blood vessels after a non-traumatic cardiac arrest to see if early findings can predict how well patients recover. It may help doctors recognize which patients are more likely to improve using simple bedside tests.
TaipeiAges 20 years+ - NCT04511013RecruitingPhase 2
Trial for BRAF-mutant melanoma spread to the brain
This Phase 2 study tests whether a 3-drug plan (encorafenib + binimetinib + nivolumab) works better than ipilimumab + nivolumab for melanoma that has spread to the brain. If you qualify, you’ll get either treatment and have frequent brain scans to track how well it controls the tumors.
Birmingham, AlabamaAges 18 years+ - NCT04511572Recruiting
Middle artery embolization for chronic brain bleeding
This study tests a procedure called middle meningeal artery embolization for people with a confirmed chronic subdural hematoma (a long-lasting bleed near the brain). It may help by reducing the blood supply to the area and improving symptoms after symptoms start or worsen.
AmsterdamAges 50–90 - NCT04516057RecruitingPhase 3
Tested medicine nabilone for agitation in Alzheimer’s dementia
This Phase 3 trial studies whether nabilone can reduce agitation (restlessness, anger, or difficult behavior) in people with Alzheimer’s dementia. It’s designed for older adults who already have agitation despite standard dementia care.
Calgary, AlbertaAges 55 years+ - NCT04516720Recruiting
Build a database of brain and spinal cord tumor cases
This study builds a large medical database of people with primary brain or spinal cord tumors treated at the Montpellier Cancer Institute. It may help researchers understand patterns of care and outcomes, which can guide future research and treatment decisions.
Montpellier, HeraultAges 18 years+ - NCT04517383Recruiting
Sedation after clot-removal brain procedure: which helps recovery
This trial compares different types of calming medicine (sedation) after a procedure to remove a brain blood clot. It aims to see whether post-procedure sedation can improve recovery in people with a serious type of stroke.
ShanghaiAges 18–85 - NCT04520178RecruitingPhase 2/Phase 3
5HTP trial for long-term spinal cord injury
This trial tests whether 5HTP can help people with spinal cord injury caused by trauma at least 6 months ago. It is mainly designed to see if the treatment is safe and helpful over the study period.
Louisville, KentuckyAges 18–65
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,425 recruiting neurology studies from the U.S. registry right now, out of 19,436 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.