Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,425 recruiting studies in this area right now.
By phase
- Not applicable9,762
- Phase 2784
- Phase 1574
- Phase 3535
- Phase 4342
- Phase 1/Phase 2305
- Phase 2/Phase 3123
Top conditions
- Stroke845
- Parkinson Disease426
- Multiple Sclerosis343
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California678
- Massachusetts300
- New York292
- Florida275
- Texas267
- Maryland245
- Arizona213
- Alabama211
- Illinois189
- Pennsylvania178
Recruiting studies12,423 total
- NCT04412187Recruiting
Study of inflammation after a new stroke
This study looks at inflammation-related changes soon after an acute ischemic stroke (a type caused by a blocked blood vessel). It may help researchers understand what factors drive recovery and how they could be targeted in the future.
Munich, GermanyAges 50 years+ - NCT04415892Recruiting
Studying a therapy target for nerve pain after chemotherapy
This study looks at “TRP channels,” which are part of how nerves sense pain and temperature, to understand nerve pain (neuropathy) after chemotherapy. It may help improve how future treatments prevent or reduce nerve pain in people who have had certain chemotherapy drugs.
Leuven, Vlaams-BrabantAges 18–75 - NCT04419272RecruitingPhase 4
Methylphenidate for thinking problems in adults with focal seizures
This trial studies whether methylphenidate (a stimulant medicine) can improve thinking and memory problems related to epilepsy. You may be kept on your usual seizure medicines, and your thinking will be tested over about 16 weeks.
Miami, FloridaAges 18 years+ - NCT04421365Recruiting
Brain–computer interface study for voice spasms from laryngeal dystonia
This study tests how a brain–computer interface reads brain signals to understand and possibly support people with a specific voice condition called adductor laryngeal dystonia. It also compares results with healthy people to help researchers see how brain activity differs during voice tasks.
Boston, MassachusettsAges 18–80 - NCT04421846Recruiting
Studying the causes of severe seizures and immune brain swelling
This study looks at what causes severe seizure episodes (“status epilepticus”) and a related immune condition that affects the brain (“dysimmune encephalitis”). The goal is to better understand the disease process, which may guide future care.
ParisAges 2 years+ - NCT04424979Recruiting
Testing prism glasses for certain types of visual field loss
This study checks whether different prism “glass” settings are feasible and helpful for people with certain types of vision field loss. You would attend testing sessions lasting about 2–4 hours to see how well the prism glasses can be used safely.
Boston, MassachusettsAges 7–80 - NCT04427241RecruitingPhase 4
Testing Cerebrolysin for prolonged brain injury after bleeding stroke
This study tests whether Cerebrolysin can improve recovery in people who remain in a vegetative or minimally conscious state more than 4 weeks after a bleeding stroke. It also tracks safety, to make sure the treatment is not causing harmful side effects.
SeoulAges 19–120 - NCT04427384Recruiting
Brain tumor patients treated with GammaTiles registry
This study is a patient registry for people with brain tumors who had surgery to remove as much as safely possible and then had GammaTiles placed. It mainly collects information and follow-up imaging to understand how patients do after the treatment.
Phoenix, ArizonaAges Any age - NCT04431609Recruiting
Study for carotid web-related stroke or TIA
This study looks at people who have had a stroke (cerebral infarction) or a warning episode (TIA) caused by a specific shape in a neck artery called a carotid web. The trial uses expert review of your imaging to confirm the cause and asks for your consent to be followed in a study group.
BordeauxAges 18 years+ - NCT04432883Recruiting
Brain stimulation to improve speech after stroke aphasia
This trial tests whether targeted mild brain stimulation (tDCS) can improve speech therapy results for people with long-lasting (chronic) aphasia after a stroke. It may help strengthen naming and communication when added to standard speech-language treatment.
Albuquerque, New MexicoAges 25–85 - NCT04433351Recruiting
Rehab training to improve speech after stroke in French speakers
This trial studies a sensory-and-movement training approach to help people relearn speech after stroke-related language difficulties. It may help if your type of post-stroke aphasia is mainly non-fluent and you can safely complete brain scans.
GrenobleAges 55–75 - NCT04434807Recruiting
Surgery soon after brain bleed vs standard care
This trial tests whether removing a certain type of brain bleed (intracerebral hemorrhage) very early, using a minimally invasive surgery approach, improves outcomes compared with standard treatment. It may help people whose bleed is large enough and who can have surgery within a strict time window.
Newcastle, New South WalesAges 18 years+ - NCT04439552Recruiting
MRI study during cornea cross-linking for keratoconus
This trial uses an MRI scan (and a close-up eye scan) to study what happens in the cornea during treatment for keratoconus. It may help doctors better understand how treatment works and who benefits most.
Boston, MassachusettsAges 8–35 - NCT04436042Recruiting
Hand brace therapy for adults with stroke-related arm weakness
This trial studies an active hand brace (orthosis) that helps improve hand use in daily life after stroke. You may be able to join if you have stroke-related hand weakness and can safely use the device as directed.
New York, New YorkAges 18 years+ - NCT04436081RecruitingPhase 2
CBD oil without THC for agitation in Alzheimer’s dementia
This trial studies whether a THC-free CBD oil softgel can reduce agitation in people with Alzheimer’s-related dementia. It compares CBD to a control to see if it improves difficult behaviors and is safe over the study period.
Norfolk, VirginiaAges 50–90 - NCT04436978RecruitingPhase 4
Best blood thinner plan for atrial fibrillation after stent
This study compares different blood-thinner (“antithrombotic”) strategies in people with atrial fibrillation or flutter who recently had a stent placed (PCI). It aims to find a plan that lowers clot risk while keeping bleeding risk as low as possible.
AalstAges 18 years+ - NCT04440254Recruiting
Long ECG monitoring for Fabry disease heart rhythm
This study checks how your heart’s electrical rhythm looks over a longer period using an ECG (a heart rhythm recording) in people with Fabry disease. It may help doctors understand heart rhythm changes better so future care can be more tailored and safer.
Paris, ParisAges 18 years+ - NCT04442971Recruiting
Music therapy for consciousness recovery after brain injury
This trial studies whether music therapy can help improve the level of consciousness in people recovering from a traumatic brain injury. If you are in early neurological rehabilitation, it may be offered as an add-on approach to support recovery.
Hessisch OldendorfAges 18–85 - NCT04443439Recruiting
MRI study to assess stroke risk from carotid narrowing
This study looks at how dangerous carotid artery narrowing (blood vessels in the neck that supply the brain) might be, using CT and MRI information. It may help doctors better judge stroke risk for people with mild, moderate, or severe narrowing.
Xi'anAges Any age - NCT04445571Recruiting
Surfactant given with a thin tube or catheter device
This trial tests two ways of giving surfactant (a lung medicine) to very premature babies with respiratory distress syndrome. It may help show which method works better and is safer for helping newborn lungs breathe.
StockholmAges Up to 2 days - NCT04445545Recruiting
Laser treatment for tight neck trigger points
This trial tests whether high-intensity laser therapy applied to specific “trigger points” in the neck muscles can help people with painful tight spots. You may be eligible if you have those trigger points and meet safety rules about recent neck/shoulder problems and skin and nerve conditions.
Santiago, Las CondesAges 18 years+ - NCT04445649Recruiting
Find factors to help people regain consciousness after brain injury
This study looks at what predicts recovery of consciousness after certain serious brain injuries, such as stroke or traumatic brain injury. It may help clinicians better identify which patients are more likely to wake up and guide early rehabilitation and care.
Hessisch OldendorfAges 18–85 - NCT04446273Recruiting
Robotic therapy timing to improve arm movement after stroke
This trial studies whether giving robotic therapy to the shoulder and arm in a “priority” way (instead of focusing on the hand first) helps improve arm movement in people with chronic stroke. It may help by improving how your arm muscles and joints are trained to work together.
Taipei, TaipeiAges 20–75 - NCT04448938Recruiting
MRI study for optic neuritis recovery signals
This study uses a special MRI scan while you rest to look for brain and eye signals that may relate to recovery in people with suspected optic neuritis. If you’re eligible, it may help researchers better understand what predicts vision improvement.
Paris, PARISAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,425 recruiting neurology studies from the U.S. registry right now, out of 19,436 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.