Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,425 recruiting studies in this area right now.
By phase
- Not applicable9,762
- Phase 2784
- Phase 1574
- Phase 3535
- Phase 4342
- Phase 1/Phase 2305
- Phase 2/Phase 3123
Top conditions
- Stroke845
- Parkinson Disease426
- Multiple Sclerosis343
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California678
- Massachusetts300
- New York292
- Florida275
- Texas267
- Maryland245
- Arizona213
- Alabama211
- Illinois189
- Pennsylvania178
Recruiting studies12,423 total
- NCT05023564Recruiting
Dementia care study following people with a steady caregiver
This study follows people diagnosed with dementia over time, with the help of a consistent caregiver, to better understand how dementia changes. It may help by adding new information that could improve future care and planning for families.
BeijingAges 18 years+ - NCT05023434Recruiting
Brain stimulation study for hand strength in brain tumor patients
This study uses brain stimulation during surgery to see how it affects hand strength and hand function. It may help doctors understand which brain areas are important for hand movement in people with certain brain tumors.
Milwaukee, WisconsinAges 18–75 - NCT05023772Recruiting
Laser and targeted radiation for spine metastases
This trial tests a combination treatment that uses a laser and focused radiation to shrink tumors in the spine and help stabilize the area near the spinal cord. It’s meant for adults with certain types of solid cancers that have limited spread in the spine and who are not good candidates for surgery.
Detroit, MichiganAges 18 years+ - NCT05024292Recruiting
Alliance study for acute stroke after clot removal
This trial tests a stroke treatment plan for adults after they have a clot removed by a catheter procedure (endovascular treatment). It focuses on people with certain artery blockages and specific scan results, aiming to improve recovery after successful clot removal.
Zhangzhou, FujianAges 18–95 - NCT05024981Recruiting
Video-based feedback and walking rehab after stroke
This trial tests whether using video feedback during walking therapy can help people regain safer walking after a recent stroke. You may be asked to walk while being video-recorded so therapists can guide your practice.
Nice, Alpes-MaritimeAges 70 years+ - NCT05025254Recruiting
Online thinking tests for people with Parkinson’s disease
This study tests online “thinking” (cognitive) abilities in people with Parkinson’s disease. It may help researchers better understand how thinking changes over time and how tests can be done from home.
Montreal, QuebecAges 45–90 - NCT05028712Recruiting
Multi-sensory rehab program for people with ultra low vision
This trial tests a rehabilitation program using multiple senses to help people with very low vision function more independently. It may help you learn new skills for daily life by using vision plus other senses.
New York, New YorkAges 12–99 - NCT05027035Recruiting
Compare diaphragm surgery versus breathing machine support
This trial is studying whether surgery, instead of using a breathing machine, works better for people with one-sided diaphragm paralysis. It aims to improve breathing comfort and function in the right patients.
GroningenAges 18 years+ - NCT05028972Recruiting
Improving how the emergency room supports people with hearing loss
This study looks at strategies to help people with hearing difficulties in VA emergency departments and measure how well those strategies work. You may be asked about your communication needs and then followed for outcomes during your emergency visit.
Aurora, ColoradoAges 60 years+ - NCT05028855Recruiting
Testing brain blood-flow control in recent carotid or MCA narrowing
This study tests how well your brain controls its own blood flow (“cerebral autoregulation”) after a recent TIA or ischemic stroke caused by a narrowed carotid or MCA artery. It may help researchers understand why symptoms happen and how to better assess brain circulation after stroke.
Changchun, JilinAges 18–80 - NCT05029726RecruitingPhase 4
Numbing medicine during back surgery to reduce pain
This trial tests a regional anesthesia (numbing medicine given near nerves) during minimally invasive lumbar spine surgery. The goal is to see if it helps control pain around surgery and improves recovery comfort.
Chicago, IllinoisAges 18–80 - NCT05033691Recruiting
Osimertinib plus early brain radiation versus osimertinib alone
This trial tests whether starting focused radiation to brain spots early (called SRS) along with osimertinib works better than taking osimertinib alone. It is for people with lung cancer that has an EGFR mutation and has not yet caused major brain symptoms.
JerusalemAges 18–120 - NCT05034172Recruiting
Study of markers in inherited movement disorders
This study looks for biological “markers” (measurable signs in the body) in people with inherited movement disorders, and in some related family members or healthy volunteers. It may help researchers better understand these conditions, especially for future diagnosis and care.
ParisAges 7 years+ - NCT05034835Recruiting
Compression garments for arm nerve pain in CRPS
This study tests whether wearing a special compression sleeve or garment can reduce pain in people with complex regional pain syndrome (CRPS) affecting the arm. It’s looking at pain changes while making sure it’s safe for your skin and blood flow.
Ploemeur, Brittany RegionAges 18 years+ - NCT05035693Recruiting
Follow-up study after a neck disc replacement surgery
This study tracks people after they get the MOVE-C artificial disc in the neck. It checks how well the device works over time and monitors safety and recovery.
ViennaAges 18 years+ - NCT05036538Recruiting
Reducing pre-surgery stress to help prevent confusion after heart surgery
This study tests whether a stress-reducing relaxation method before heart surgery can lower the risk of postoperative delirium (sudden confusion) and longer-term thinking problems. It may help you keep clearer thinking in the days and weeks after surgery.
Bad Nauheim, HesseAges 18 years+ - NCT05040373Recruiting
Pregnancy follow-up after patisiran exposure
This program tracks pregnancy outcomes for people who were exposed to patisiran (a medicine) in a special delivery form called LNP during pregnancy or shortly before. It helps doctors understand potential effects and safety for mothers and babies.
Iowa City, IowaAges Any age - NCT05042258RecruitingPhase 4
Dupilumab to improve sleep and itch in children with eczema
This trial studies whether dupilumab can improve daily body clock (circadian function), sleep, and itching in children with moderate-to-severe eczema that isn’t well controlled by creams. It may help kids who are having significant sleep trouble and ongoing itch.
Chicago, IllinoisAges 6–17 - NCT05041387Recruiting
Collecting standard care data for nerve and muscle tests
This study collects information from people who may have a nerve or muscle problem or a nerve-degenerating illness, based on the usual care they already receive. It may help researchers understand symptoms and test results in real-world patients.
Bethesda, MarylandAges 18–110 - NCT05045950RecruitingPhase 2
Whole brain radiation that aims to protect thinking skills
This Phase 2 trial tests a modified form of whole brain radiation to see if it can better protect thinking and memory in adults with brain metastases. You may join even if you’ve had other cancer treatments before, as long as your situation fits the study rules.
Milwaukee, WisconsinAges 18 years+ - NCT05044208Recruiting
Test heart ultrasound and monitoring clues for atrial fibrillation
This study looks at heart ultrasound pictures and heart-rhythm recordings to predict who may develop atrial fibrillation (AF) after a stroke or TIA. If you qualify, your results may help doctors better spot people at higher risk earlier.
TullnAges 18 years+ - NCT05044520Recruiting
Study of what restless legs feels like
This study looks at the different symptoms and experiences people have with restless legs syndrome. It may help researchers better understand the condition so care can improve for patients.
MontpellierAges 18 years+ - NCT05046613Recruiting
Pregnancy outcomes after rimegepant use for migraine
This observational study looks at health outcomes for moms, babies, and infants after rimegepant is used during pregnancy for migraine. It may help doctors understand potential risks or reassuring safety information for future pregnancies.
Wilmington, North CarolinaAges birth+ - NCT05048004Recruiting
Test of a heart procedure during atrial fibrillation ablation
This trial studies whether adding a specific technique during a first-time catheter ablation for atrial fibrillation can improve safety or outcomes. It may help doctors understand risks related to small blood clots during the procedure.
BerlinAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,425 recruiting neurology studies from the U.S. registry right now, out of 19,436 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.