Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,425 recruiting studies in this area right now.
By phase
- Not applicable9,762
- Phase 2784
- Phase 1574
- Phase 3535
- Phase 4342
- Phase 1/Phase 2305
- Phase 2/Phase 3123
Top conditions
- Stroke845
- Parkinson Disease426
- Multiple Sclerosis343
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California678
- Massachusetts300
- New York292
- Florida275
- Texas267
- Maryland245
- Arizona213
- Alabama211
- Illinois189
- Pennsylvania178
Recruiting studies12,423 total
- NCT05261607Recruiting
Study outcomes for people in the intensive care unit
This study looks at how mortality (whether patients survive) changes over time for people treated in an intensive care unit. It may help hospitals understand what happens to ICU patients and improve care planning.
Getafe, MadridAges Any age - NCT05261477Recruiting
Kid Brain Injury Education and Care Navigation Program
This trial tests a family support program that teaches caregivers and helps coordinate outpatient care after a traumatic brain injury. It may help families better understand recovery and connect with rehabilitation services.
Colorado Springs, ColoradoAges 3 years+ - NCT05262543Recruiting
Study predicts risk of RBD turning into Parkinson’s
This study looks at people diagnosed with idiopathic REM sleep behavior disorder (a sleep problem where you act out dreams) and tries to predict who may later develop another condition related to Parkinson’s. If you qualify and consent, you may be followed to understand risk factors and improve early identification.
Oggebbio, VerbaniaAges 18 years+ - NCT05262439Recruiting
Follow-up study of CPAP mask systems for sleep apnea
This study checks how ResMed CPAP mask systems work in real-life use for people with obstructive sleep apnea (OSA). It may help improve comfort, fit, and performance based on what patients experience over time.
Sydney, New South WalesAges 18–100 - NCT05263674RecruitingPhase 3
Faster ICU treatment for non-convulsive seizures in adults
This study compares two ways to stop non-convulsive seizures in the ICU. It tests whether fast sedation in intensive care works better than giving higher-dose anti-seizure medicine through a vein.
AarhusAges 18–120 - NCT05263596Recruiting
Testing ways to diagnose muscle loss in older adults
This study looks for the best ways to detect sarcopenia, which means age-related loss of muscle strength and mass, in older people in a hospital or care setting. It may help doctors spot muscle problems earlier so they can plan better care.
BaselAges 65 years+ - NCT05263804Recruiting
Study uses MRI and blood clues after ischemic stroke
This study looks for biological and imaging markers that may predict heart/vascular outcomes after an ischemic stroke. You may join if you are eligible for standard stroke treatment and can complete planned follow-up and MRI scans.
BronAges 18 years+ - NCT05266872Recruiting
Earlier diagnosis and better treatment study for Parkinson’s
This study is looking to improve how Parkinson’s and related brain conditions are identified and treated sooner. You may be asked to share your health information and provide blood or other samples, and possibly have procedures like a spinal fluid test or a small skin sample.
LuxembourgAges 18 years+ - NCT05267808Recruiting
Using sleep study patterns to guide future OSA treatment
This study looks at results from a sleep test to better understand the different types (“endotypes”) of obstructive sleep apnea. Your information may help doctors choose the next best step—often a procedure called drug-induced sleep endoscopy (DISE)—to guide treatment.
EdegemAges 18 years+ - NCT05267184Recruiting
Embolization versus surgery for long-term brain blood collections
This trial compares two ways to treat a chronic subdural hematoma (a long-lasting bleed between the brain and its covering): blocking a specific artery versus standard surgery to remove the blood. It may help you and your care team choose the safer and more effective option for your situation.
GothenburgAges 18–89 - NCT05268341Recruiting
MRI study of language therapy changes in children
This study uses MRI pictures to see how a language-focused treatment may change the brain in children with Developmental Language Disorder (DLD). It’s for children who have typical speech, social skills, and hearing, but specifically struggle with expressive grammar.
Cincinati, OhioAges 4 years–5.9 years - NCT05268861Recruiting
Understanding brain learning after stroke during arm training
This study looks at how thinking and brain processes affect learning to move your arm after a stroke. You may be asked to do arm tasks in a way that helps the researchers understand what helps or limits motor learning.
Laval, QuebecAges 40–75 - NCT05268887Recruiting
Light, sound, and touch therapy for Parkinson’s symptoms
This trial tests whether high-frequency light, sound, and gentle touch can improve movement and thinking problems in people with Parkinson’s disease. You may help the researchers learn if this kind of stimulation is safe and beneficial alongside your usual Parkinson’s medications.
Cambridge, MassachusettsAges 45–90 - NCT05269628RecruitingPhase 2
Cannabidiol for multiple sclerosis sleep and pain patterns
This study looks at whether cannabidiol (CBD, a cannabis-related medicine) can improve symptoms in people with multiple sclerosis (MS), especially how sleep and pain type affect outcomes. It’s mainly for people with MS and ongoing moderate-to-severe pain, while carefully checking safety and medication interactions.
Ann Arbor, MichiganAges 18–65 - NCT05269472Recruiting
Study of nerve signals during facial pain procedures
This study measures nerve activity (electrical signals in nerves) in people who have trigeminal neuralgia and are getting a common facial pain procedure. It may help researchers better understand the condition and improve future treatments.
Minneapolis, MinnesotaAges 18 years+ - NCT05271240RecruitingPhase 3
Targeted brain-artery drug added to standard treatment for new GBM
This Phase 3 trial tests whether delivering a cancer drug directly into brain blood vessels, along with standard radiation and temozolomide, works better than standard treatment alone in newly diagnosed glioblastoma (GBM). The goal is to improve control of the tumor while comparing side effects between the two approaches.
New York, New YorkAges 18 years+ - NCT05273216Recruiting
Study blood vessel injury after clot removal for stroke
This trial looks at how blood flow damage (“reperfusion injury”) happens after mechanical clot removal in certain stroke types. It may help doctors better prevent complications after the procedure.
Graz, StyriaAges 18 years+ - NCT05277129Recruiting
Study of the immune response soon after stroke
This study looks at how your body’s immune system reacts in the first hours after a stroke. It may help researchers understand stroke-related immune changes and improve future treatments.
LørenskogAges 18 years+ - NCT05282277RecruitingPhase 4
Estradiol to improve brain and reward changes in midlife women
This study tests whether a hormone called estradiol (given as a patch and pill) changes how the brain and body respond to reward in some midlife women with low pleasure and/or psychosis symptoms during menopause transition. It may help researchers understand whether estrogen treatment can improve mood-related “reward” function in this group.
Chapel Hill, North CarolinaAges 45–55 - NCT05278715RecruitingPhase 2
New treatment plan for optic pathway glioma in children
This Phase 2 trial tests a modified chemotherapy treatment plan for children and young people with optic pathway glioma, aiming to shrink tumor and improve eye/brain symptoms. You may be able to join if your diagnosis is confirmed and your body can safely handle treatment.
BeijingAges 3 months–21 years - NCT05281055Recruiting
Registry of clot-removal treatment for sudden large-vessel strokes
This study keeps a record of people treated with a clot-removal procedure (endovascular thrombectomy) for a sudden stroke caused by a blocked large blood vessel in the brain. It focuses on outcomes for patients who can be treated within 24 hours and were independent before the stroke.
TaipeiAges 20 years+ - NCT05283265Recruiting
Study brain signals during language understanding
This study looks at brain activity while you do language tasks, to understand what brain signals are linked to understanding words. You may help researchers learn more about neurophysiological mechanisms of language comprehension using existing brain-monitoring care.
Birmingham, AlabamaAges 18 years+ - NCT05281887Recruiting
Study of eye changes after ischemic stroke
This trial looks at how changes in the retina (the light-sensing tissue in the back of the eye) track with vision and eye function after an ischemic stroke. The goal is to understand which eye changes are linked to the stroke, which could help doctors monitor recovery.
Guangzhou, GuangdongAges 18 years+ - NCT05282550RecruitingPhase 2
Trazodone trial to improve sleep in early Alzheimer’s
This study tests whether the sleep medicine trazodone can improve thinking and memory in people with early Alzheimer’s-related changes who also have sleep problems. If better sleep helps the brain, it may improve memory test results over time.
Baltimore, MarylandAges 55 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,425 recruiting neurology studies from the U.S. registry right now, out of 19,436 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.