Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,425 recruiting studies in this area right now.
By phase
- Not applicable9,762
- Phase 2784
- Phase 1574
- Phase 3535
- Phase 4342
- Phase 1/Phase 2305
- Phase 2/Phase 3123
Top conditions
- Stroke845
- Parkinson Disease426
- Multiple Sclerosis343
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California678
- Massachusetts300
- New York292
- Florida275
- Texas267
- Maryland245
- Arizona213
- Alabama211
- Illinois189
- Pennsylvania178
Recruiting studies12,423 total
- NCT05283993Recruiting
Hospital study following people with plasma cell disorders
This is a hospital-based study that follows people with plasma cell disorders to better understand these conditions. It mainly gathers information from patients who are confirmed to have one of several related diseases.
BeijingAges Any age - NCT05284643Recruiting
MRI-guided radiation and Avastin for recurrent brain glioblastoma
This trial tests whether using special MRI information to plan proton radiation, plus a drug called Avastin (bevacizumab), can help control recurrent glioblastoma (a fast-growing brain tumor) and improve outcomes. It mainly aims to treat tumor that has come back after prior standard radiation, using careful timing and imaging to target it safely.
Miami, FloridaAges 18 years+ - NCT05285059Recruiting
Study how children with epilepsy learn
This trial studies how children with epilepsy learn and process information compared with children without brain, mental health, or learning conditions. It may help researchers understand the learning needs of children living with epilepsy.
Bron, BronAges 8–14 - NCT05286151Recruiting
Studying brain connectivity and timing in stuttering and nonstuttering teens
This study looks at how brain “networks” connect and how timing works in adolescents who stutter compared with those who don’t. It may help researchers better understand what underlies stuttering and how it differs from typical speech timing.
Ann Arbor, MichiganAges 9–13 - NCT05287750Recruiting
Brain disease study using 7.0T brain MRI scans
This study looks at people with brain conditions using a very strong MRI scanner (7.0T). It may help doctors understand brain diseases better and improve how scans are used, but you must be able to safely have the MRI (and possibly contrast dye).
BeijingAges 18–80 - NCT05288842Recruiting
Study spinal fluid and brain changes in dementia types
This study looks at spinal fluid and MRI results in people with Alzheimer’s disease, frontotemporal dementia, or normal thinking (controls). It aims to understand differences in brain-related cells and measure what might help explain or track these conditions.
LilleAges 40–85 - NCT05289934Recruiting
Recorded music to see how it affects seizures
This study is testing whether listening to recorded music can change seizure activity and brain-wave patterns in children monitored in an epilepsy center. Your child might benefit by helping researchers learn how music could affect seizures during close observation.
Baltimore, MarylandAges 4–17 - NCT05290610Recruiting
Brain stimulation mapping during epilepsy surgery planning
This study uses a special kind of brain recording with stimulation to better map seizure activity while you are already having monitoring for epilepsy surgery. It may help doctors understand how to plan safer, more effective treatment.
Minneapolis, MinnesotaAges 18 years+ - NCT05293197RecruitingPhase 1
Safety study of repeated blood-brain barrier opening for pediatric brain tumors
This Phase 1 study tests whether a device can safely and repeatedly open the blood-brain barrier (a protective shield in the brain) in children with malignant brain tumors. It aims to help the tumor treatment work better while watching for safety issues.
ParisAges 5–17 - NCT05292794Recruiting
CereGate therapy for freezing of gait in Parkinson’s
This trial tests whether CereGate therapy can reduce “freezing of gait,” a walking problem, in people with Parkinson’s disease who already have deep brain stimulation (DBS). If you meet the device and medication stability requirements, the study may help your walking and movement symptoms measured during testing.
Redwood City, CaliforniaAges 21–80 - NCT05293080RecruitingPhase 3
Early heart rhythm treatment to help prevent stroke
This trial tests an early treatment approach for people who had a recent ischemic stroke (a stroke caused by a blocked blood vessel) and have an irregular heart rhythm called atrial fibrillation (AF). It aims to lower the chance of having another stroke by treating AF as early as possible after the stroke.
HamburgAges 18 years+ - NCT05293600RecruitingPhase 1/Phase 2
Rescue medicine trial for sleep apnea after other treatments fail
This trial studies a “rescue” set of medicines for obstructive sleep apnea when two common treatments haven’t worked well enough. If you still have frequent breathing pauses during sleep, the study may test whether these medicines can reduce them and improve safety and symptoms.
Boston, MassachusettsAges 21–70 - NCT05293184Recruiting
Angelman syndrome registry to track symptoms worldwide
This trial is building a global registry for people diagnosed with Angelman syndrome. It helps researchers learn more about how symptoms change over time, which can support future studies and treatments.
Brisbane, QueenslandAges Any age - NCT05295498Recruiting
Brain stimulation trial for nerve pain relief
This trial studies whether repeated magnetic stimulation of the brain can reduce ongoing nerve pain. It may help people whose nerve pain has been steady for at least a month and who still need pain medicine more than once a week.
KrakowAges 18 years+ - NCT05295615Recruiting
Pulsed magnetic treatment for mild to moderate Alzheimer’s
This trial tests whether a pulsed electromagnetic field (a non-drug device that uses magnetic pulses) can help people with mild to moderate Alzheimer’s. Participants typically stay on stable Alzheimer’s medicines and follow daily home treatments during the study.
Hackensack, New JerseyAges 50–100 - NCT05295810Recruiting
Breathing test for people with low blood pressure on standing
This study checks how your body controls breathing and heart rate when you stand up, especially if you get dizzy from low blood pressure. It may help researchers understand what causes symptoms and how to improve testing for people with this condition.
Calgary, AlbertaAges 18–100 - NCT05295862Recruiting
Stroke registry for adults after acute stroke
This study enrolls adults who are admitted to the hospital for a sudden (acute) stroke. It mainly collects information about your care and recovery to help improve stroke treatment in the future.
Giessen, HesseAges 18 years+ - NCT05296408Recruiting
Arm exoskeleton rehab for chronic stroke weakness
This trial tests a wearable arm exoskeleton that uses your muscle signals to help rehab a weak arm after stroke. It may help improve arm movement by pairing training with this device, but you must meet specific movement, skin, and scan-safety requirements.
Cleveland, OhioAges 18–89 - NCT05296980Recruiting
Testing a dementia risk-reduction program for older adults
This study checks whether a program called REMINDER can help reduce risk of developing dementia by improving risk factors over 12 weeks. It’s for older adults who have higher dementia risk but do not currently have dementia.
CoimbraAges 60–75 - NCT05298436Recruiting
South London stroke registry using health data
This study collects information about people who have had a stroke to learn how to improve care and support. It mainly uses existing medical and health records rather than testing a new medicine.
LondonAges 18 years+ - NCT05298995RecruitingPhase 1
GD2 CAR T-cell treatment for pediatric brain tumors
This trial tests a special immune-cell therapy (GD2 CAR T cells) made for pediatric brain tumor patients. It uses a planned treatment plan and monitoring to see if the therapy is safe and can work against the tumor.
Roma, ItalyAges 6 months–30 years - NCT05299749Recruiting
Brain training using real-time fMRI for hearing voices in schizophrenia
This trial tests whether real-time brain imaging “neurofeedback” can help people with schizophrenia who have ongoing auditory hallucinations (hearing voices) that haven’t improved with medications. If you qualify, you may complete brain-scanning sessions where you practice changing brain activity while being monitored.
Brockton, MassachusettsAges 18–55 - NCT05299710Recruiting
Store ovarian tissue for future fertility in children
This study looks at freezing (cryopreserving) ovarian tissue before certain cancer treatments or surgeries that may affect fertility. It may help preserve the ability to have children later, especially when future fertility is at risk.
Chicago, IllinoisAges Up to 11 years - NCT05300997Recruiting
Test blood and antibody markers for suspected acute stroke
This study looks at blood tests to find signs of immune activity after a suspected stroke. It may help doctors diagnose stroke faster and better understand what is happening in the body soon after symptoms start.
Hong KongAges 18–100
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,425 recruiting neurology studies from the U.S. registry right now, out of 19,436 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.