Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 11,952 recruiting studies in this area right now.
By phase
- Not applicable9,355
- Phase 2761
- Phase 1558
- Phase 3514
- Phase 4339
- Phase 1/Phase 2300
- Phase 2/Phase 3125
Top conditions
- Stroke798
- Parkinson Disease395
- Alzheimer Disease338
- Multiple Sclerosis328
- Dementia226
- Epilepsy193
- Ischemic Stroke190
- Insomnia159
- Traumatic Brain Injury151
- Obstructive Sleep Apnea142
- Spinal Cord Injuries142
- Acute Ischemic Stroke138
- Sarcopenia134
- Mild Cognitive Impairment127
- Cerebral Palsy119
- Pain Management116
- Migraine107
- Fibromyalgia104
Leading sponsors
- Beijing Tiantan Hospital124
- Assistance Publique - Hôpitaux de Paris109
- Riphah International University105
- Mayo Clinic98
- VA Office of Research and Development92
- Xuanwu Hospital, Beijing89
- Hospices Civils de Lyon77
- Johns Hopkins University69
- University of Minnesota63
- Washington University School of Medicine63
Where studies are running
- California661
- Massachusetts305
- New York295
- Florida272
- Texas266
- Maryland248
- Alabama207
- Arizona206
- Illinois181
- Pennsylvania177
Recruiting studies11,952 total
- NCT05004610RecruitingPhase 2
Hypertonic lactate treatment after cardiac arrest
This trial studies whether giving a specific IV fluid (hypertonic lactate) soon after resuscitation from cardiac arrest can improve recovery. It is for adults who remain in a deep unresponsive state after return of spontaneous circulation.
Brussels, BelgiumAges 18 years+ - NCT05390268Recruiting
Mobile app behavioral therapy for youth with tic disorders
This trial tests whether a mobile app can help children and teens reduce tic symptoms using behavioral treatment strategies. It may help if your tics are affecting your daily life and you have not had very recent tic-specific behavioral training.
Aarhus N, RisskovAges 9–17 - NCT05629559RecruitingPhase 1/Phase 2
Study drug 4D-310 for Fabry disease with heart problems
This Phase 1/2 study tests how safe and potentially effective 4D-310 is for adults with Fabry disease who have heart involvement. It may help people who can’t tolerate standard treatments like enzyme replacement therapy (ERT) or migalastat, or who still have disease progression.
MelbourneAges 18–65 - NCT06624488Recruiting
Brain injury markers after cardiac arrest and outlook
This study looks at certain proteins in the fluid around the brain and in the blood after a cardiac arrest. These proteins may help doctors predict how the patient will recover, which could guide their care.
BeijingAges 18–80 - NCT06093126RecruitingPhase 4
Lemborexant for insomnia in dementia: a personalized trial
This trial tests if the sleep medication lemborexant can help people with early-stage dementia who also have insomnia. It uses an N-of-1 design, meaning it will look at how you personally respond to the drug compared to a placebo.
Halifax, Nova ScotiaAges Any age - NCT06608797Recruiting
Computer-based cognitive training for multiple sclerosis patients
This study tests whether a computer-based cognitive training program is helpful and practical for people with multiple sclerosis who live in the community. It focuses on those who have some memory or learning difficulties.
East Hanover, New JerseyAges 19–65 - NCT06598657Recruiting
Gentle ankle mobilization for spastic cerebral palsy
This study tests a gentle ankle movement therapy to improve walking in children with spastic cerebral palsy. It may help reduce leg stiffness and make walking easier.
Islamabad, Punjab ProvinceAges 8–18 - NCT06735053Recruiting
Virtual reality physiotherapy for multiple sclerosis patients
This trial tests whether virtual reality exercises can help people with advanced multiple sclerosis improve their movement and walking. You may qualify if you need two walking aids and your MS has been stable for the last six months.
Móstoles, MadridAges 18–70 - NCT06738381Recruiting
Digital prevention program after heart attack or stroke
This trial tests a digital program (using a smartphone or tablet) to help prevent another heart attack or stroke. It is for people who have already had a heart-related event or have known artery plaque buildup.
Drammen, BuskerudAges 18 years+ - NCT06837844Recruiting
Pain relief study for knee replacement surgery
This trial tests a combination of two pain-relief methods after total knee replacement: a spinal injection and a nerve block in the thigh. It aims to provide better pain control during and after surgery.
Kafr ash Shaykh, KafrelsheikhAges 18–75 - NCT06839118RecruitingPhase 3
Botox for headaches after head injury
This trial tests if Botox injections can reduce headache days in people with persistent headaches after a mild head injury. It may help if you have headaches at least 15 days a month.
Glostrup MunicipalityAges 18–80 - NCT06842329Recruiting
Can distraction ease injection pain for teens with period pain?
This study tests whether using simple distraction techniques during a shot can reduce pain in teenage girls who come to the emergency room with severe menstrual cramps.
SamsunAges 12–18 - NCT07372430Recruiting
Nerve block comparison for buttock nerve pain
This study compares two ways of giving a numbing injection (nerve block) to treat a condition where a nerve in the low back gets pinched, causing long-term buttock or low back pain. It aims to see which method works better.
IstanbulAges 18–75 - NCT06351839Recruiting
Sleep better despite long-term pain
This trial tests a program to help people with chronic pain and insomnia sleep better. It focuses on combining pain management with sleep improvement strategies.
Tromsø, Troms CountyAges 18–75 - NCT06316778Recruiting
Pelvic floor training for women with myotonic dystrophy
This study tests whether pelvic floor muscle training (exercises to strengthen the muscles that control urine flow) can help women with myotonic dystrophy type 1 who have bladder leakage. It's a gentle, non-surgical approach that may improve quality of life.
Jonquière, QuebecAges 18 years+ - NCT07374263Recruiting
Do heart rhythm drugs pose risks in hospital?
This study looks at whether certain medications that can affect heart rhythm (QT-prolonging drugs) are linked to serious heart problems in adults who were hospitalized. It includes patients admitted to St. Joseph's Healthcare Hamilton or other GEMINI hospitals between 2017 and 2025.
Hamilton, OntarioAges 18 years+ - NCT07376278Recruiting
Deep brain stimulation outcomes in Parkinson's disease
This study looks at factors that predict how well deep brain stimulation (DBS) works for people with Parkinson's disease. If you are considering DBS, joining this research could help doctors better understand who benefits most from the procedure.
Hong KongAges 18–75 - NCT07373366RecruitingPhase 2
Noninvasive brain stimulation for TBI patients and healthy volunteers
This trial tests whether a noninvasive brain stimulation technique can help people who have suffered a traumatic brain injury (TBI), specifically those with diffuse axonal injury (DAI). It also includes healthy volunteers for comparison.
São Paulo, São PauloAges Any age - NCT07378189Recruiting
Opioid-free anesthesia for pancreatic surgery
This trial tests whether using a combination of non-opioid drugs during general anesthesia can reduce side effects after laparoscopic pancreatic surgery. If you are scheduled for this type of surgery and are between 18 and 80 years old, you may be able to join.
Krakow, Lesser Poland VoivodeshipAges 18–80 - NCT07373587Recruiting
Nutrition and exercise plan to prevent disability in older patients
This trial tests whether a personalized diet and exercise program can help older adults avoid losing function while in the hospital. If you are staying in a geriatric ward and can follow instructions, this study may help you stay stronger and more independent.
Copenhagen, Capital RegionAges 65 years+ - NCT07377032RecruitingPhase 3
L-serine for GRIN-related neurodevelopmental disorders
This trial tests whether an amino acid supplement called L-serine can help people with GRIN-related neurodevelopmental disorders. These disorders are caused by specific genetic changes that affect brain function, and the study aims to see if L-serine can improve symptoms.
LyonAges 2–30 - NCT07372833Recruiting
CAMK2-related brain disorders natural history study
This study tracks the health and development of people with a specific genetic change in the CAMK2 genes. By joining, you help researchers understand the condition better, which may lead to better treatments in the future.
Rotterdam, South HollandAges Any age - NCT07378592Recruiting
Driving simulator training for adults with brain injury
This trial tests a driving simulator training program to help adults with acquired brain injuries regain skills and confidence behind the wheel. If you have a brain injury and a valid license, you may be able to join.
Fairfield, ConnecticutAges 18 years+ - NCT07377058Recruiting
Tocilizumab study for anti-MDA5 positive dermatomyositis
This trial tests if adding the drug tocilizumab to standard therapy helps people with a rare type of dermatomyositis (anti-MDA5 positive) that often affects the lungs. It compares tocilizumab to a placebo to see if it can improve symptoms and lung function.
Beijing, Beijing MunicipalityAges 18–65
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 11,952 recruiting neurology studies from the U.S. registry right now, out of 18,491 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.