Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,425 recruiting studies in this area right now.
By phase
- Not applicable9,762
- Phase 2784
- Phase 1574
- Phase 3535
- Phase 4342
- Phase 1/Phase 2305
- Phase 2/Phase 3123
Top conditions
- Stroke845
- Parkinson Disease426
- Multiple Sclerosis343
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California678
- Massachusetts300
- New York292
- Florida275
- Texas267
- Maryland245
- Arizona213
- Alabama211
- Illinois189
- Pennsylvania178
Recruiting studies12,423 total
- NCT05691569Recruiting
Doll therapy for agitation in moderate to severe dementia
This trial tests whether using a realistic doll can reduce agitation and aggressive behaviors in people with moderate to severe dementia during a hospital stay. It may help some patients feel calmer and more comfortable through structured interaction.
Lausanne, Canton of VaudAges 65 years+ - NCT05692882Recruiting
Registry for stent treatment in narrowed brain arteries in China
This study records outcomes for people with significant narrowing in brain arteries who have treatment using a drug-eluting stent. It may help doctors understand how well this approach works and what risks or benefits to expect.
ChenzhouAges 18–85 - NCT05692973Recruiting
Study tests how reading skill affects thinking
This study looks at how difficulty reading might change how people make judgments and decisions. You may be asked to complete reading and thinking tasks, and the researchers compare results by reading performance.
Excelsior Springs, MissouriAges 8–14 - NCT05694039Recruiting
Track thinking changes in older adults with hearing loss
This study follows older adults who have age-related hearing loss to see whether wearing hearing aids helps protect thinking and memory over time. You may be included if your hearing loss is the type that hearing aids can usually improve and if your thinking test scores suggest mild cognitive difficulties.
Guangzhou, GuangdongAges 60–85 - NCT05695131Recruiting
Testing virtual reality speech therapy for adults
This study checks whether a virtual reality (VR) version of a speech-language therapy program is practical and works the way it should. You might benefit by getting speech therapy in a new, technology-based format, and helping researchers confirm it is safe and feasible.
Edmonton, AlbertaAges 18 years+ - NCT05695963Recruiting
Daily phone check-ins for restless legs symptoms
This study uses frequent, brief check-ins (often by phone) to better understand restless legs syndrome symptoms in daily life. It may help researchers learn patterns of symptoms that could improve future care plans.
BordeauxAges 18–70 - NCT05697575Recruiting
Staphylokinase during stroke blood-flow treatment
This trial studies using a medication called non-immunogenic staphylokinase as part of standard clot-busting treatment for an acute ischemic stroke. It may help clinicians improve blood flow after the stroke using an approach designed to be less likely to trigger immune reactions.
Saint PetersburgAges 18–85 - NCT05698901Recruiting
Testing heart blood tests and scans to monitor Fabry disease
This study checks whether certain heart-related blood tests and heart scans can help monitor people with Fabry disease. It may be useful for both people who have never received enzyme replacement therapy and those who have.
TaipeiAges 18 years+ - NCT05700058Recruiting
Testing how different Super-whey doses affect muscle growth
This study checks how different doses of “Super-whey” influence muscle protein building in adults. It may help figure out the best whey dose for building muscle, especially in older adults.
DerbyAges 65–85 - NCT05700721RecruitingPhase 2
Niraparib and dostarlimab for cancer with growing brain spots
This trial studies whether the medicines niraparib and dostarlimab can slow advanced cancers that have active, growing brain metastases. It is meant for people whose brain tumors can be measured on MRI and who have had at least one previous treatment.
Houston, TexasAges 18 years+ - NCT05700825RecruitingPhase 2
Rehab training to improve swallow safety in Parkinson’s
This trial tests a rehabilitation approach aimed at improving airway protection during swallowing in people with Parkinson’s disease. It may help reduce the risk of food or liquid going down the wrong way by improving swallow safety.
West Lafayette, IndianaAges 50–90 - NCT05701059Recruiting
Tests different artificial discs for neck nerve and spinal cord problems
This trial compares two types of artificial disc implants used for certain neck problems. It may help people who have tried non-surgical treatments but still have ongoing nerve symptoms or spinal cord issues from a damaged disc in the neck.
Los Angeles, CaliforniaAges 18–60 - NCT05701969RecruitingEarly Phase 1
Melatonin for sleep during night shifts in residents
This early study tests whether melatonin can improve sleep patterns for doctors-in-training during overnight “night float” shifts. It may help you feel more rested and adjust to night work.
Charlottesville, VirginiaAges 18 years+ - NCT05702138RecruitingPhase 2
High-intensity walking training for recent brain injury
This Phase 2 study tests whether high-intensity, treadmill-based step training can improve walking after a traumatic brain injury (TBI). It may help people who are still having trouble with walking speed and can follow instructions.
Englewood, ColoradoAges 18 years+ - NCT05702749Recruiting
Vestibular physical therapy before treatment for acoustic tumors
This trial tests whether physical therapy focused on balance and dizziness before surgery or targeted radiation (SRS) can improve how people with vestibular schwannoma (an acoustic tumor) feel and function. It aims to help prepare your balance system before treatment begins.
Milwaukee, WisconsinAges 18 years+ - NCT05703386Recruiting
Study MRI changes in small-vessel stroke disease
This study looks at how “small-vessel” changes in the brain develop after an ischemic stroke, using repeated MRI scans. It may help researchers better understand what causes these changes and how to track them over time.
Baltimore, MarylandAges 18 years+ - NCT05703347Recruiting
Mobile app coaching to improve sleep and prevent childhood obesity
This study tests a mobile health app that helps children get better sleep, aiming to support healthier weight over time. It is designed for children who are getting less sleep than recommended and are in the higher-but-not-highest weight range for their age.
Philadelphia, PennsylvaniaAges 8–12 - NCT05703711Recruiting
MHealth plus nurse care for mental health in West Africa
This trial tests whether combining phone-based support (mHealth) with regular nurse-delivered care can improve outcomes for people with serious mental illness. You might benefit if you’re currently in an inpatient prayer camp and living with psychosis, mania, or depression.
AccraAges 18 years+ - NCT05705453Recruiting
Spinal cord stimulation study for long-term spinal injury outcomes
This study looks at how spinal cord stimulation affects long-term recovery and daily functioning in people with stable spinal cord injury. You may be eligible if you already have an implanted, FDA-approved spinal cord stimulator and meet specific safety and timing rules.
Minneapolis, MinnesotaAges 22 years+ - NCT05705778Recruiting
Blood biomarker study in children with amblyopia
This trial looks at a blood test (a “biomarker”) in children with amblyopia, a common vision development problem. It may help researchers understand what changes go along with treatment and vision improvement.
Guangzhou, GuangdongAges 3–12 - NCT05705999Recruiting
TMS treatment plus CBIT study for Tourette’s tics
This trial tests whether a treatment called TMS, added to an evidence-based therapy called CBIT, can reduce Tourette’s tics more than CBIT alone. You may be assigned to different study groups, and they will also use brain imaging to measure changes.
Morgantown, West VirginiaAges 18–100 - NCT05706194Recruiting
Early brain prognosis test after out-of-hospital cardiac arrest
This trial studies how to predict brain recovery early after a non-traumatic out-of-hospital cardiac arrest. The goal is to help clinicians estimate outcome sooner, which may improve decision-making during intensive care.
HelsinkiAges 18–100 - NCT05706831Recruiting
Music and gentle brain stimulation after neurological injury
This trial tests whether combining music with gentle electrical brain stimulation can improve symptoms after a neurologic event, such as language and attention problems. It’s meant for adults who are living with effects of stroke and certain levels of reduced awareness.
Bari, BaAges 18 years+ - NCT05707442RecruitingPhase 3
Stent or standard treatment for idiopathic intracranial hypertension
This Phase 3 trial compares putting in a venous sinus stent versus using medicine alone for idiopathic intracranial hypertension (IIH). It aims to see which approach better protects vision and lowers pressure in the brain.
Beijing, Beijing MunicipalityAges 18–60
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,425 recruiting neurology studies from the U.S. registry right now, out of 19,436 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.