Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,425 recruiting studies in this area right now.
By phase
- Not applicable9,762
- Phase 2784
- Phase 1574
- Phase 3535
- Phase 4342
- Phase 1/Phase 2305
- Phase 2/Phase 3123
Top conditions
- Stroke845
- Parkinson Disease426
- Multiple Sclerosis343
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California678
- Massachusetts300
- New York292
- Florida275
- Texas267
- Maryland245
- Arizona213
- Alabama211
- Illinois189
- Pennsylvania178
Recruiting studies12,423 total
- NCT05677243Recruiting
Observational study of radiosurgery for trigeminal neuralgia pain
This study follows people with trigeminal neuralgia to see how radiosurgery treatment affects their facial pain. It may help doctors better understand who benefits when medicines do not control the pain enough.
MonacoAges 18 years+ - NCT05677607Recruiting
Study of brain artery narrowing and small-vessel disease
This study looks at how two types of blood vessel problems in the brain affect each other over time. It may help researchers better understand what to watch for and potentially how to improve outcomes.
Beijing, Beijing MunicipalityAges 30 years+ - NCT05679024RecruitingPhase 3
Apixaban to prevent stroke in atrial fibrillation and kidney failure
This trial tests apixaban (a blood thinner) to prevent stroke in people with atrial fibrillation or atrial flutter who have very poor kidney function or are on dialysis. If you qualify, you may help researchers find a safer way to lower stroke risk for this higher-risk group.
HelsinkiAges 18 years+ - NCT05678634Recruiting
Feedback training for children with language learning difficulties
This study tests a learning program that gives children feedback to help improve language and communication skills. It may help children who have developmental language difficulties and can understand instructions in English.
Boston, MassachusettsAges 8–12 - NCT05679271Recruiting
Stent treatment for low-grade dural AV fistula causing ringing
This trial tests whether placing a small tube (stent) inside a brain vein-sinus can reduce a pulsating ringing sound caused by a “dural arteriovenous fistula” (DAVF). It’s for people whose tinnitus matches the DAVF location and who meet imaging and medication safety requirements.
BordeauxAges 18 years+ - NCT05680597Recruiting
Video balance rehab program for Parkinson’s symptoms
This trial tests a 4-week, at-home video rehabilitation program focused on balance problems in people with Parkinson’s disease. It aims to see whether this tele-rehab approach helps with walking and stability while keeping medications steady.
Portland, OregonAges 55–85 - NCT05681299RecruitingPhase 4
Testing growth hormone and liraglutide effects on hunger hormones
This study tests how growth hormone (GH) and liraglutide affect a hunger-related hormone system called AgRP. It compares effects in healthy people (lean or overweight) and in people with isolated GH deficiency, aiming to understand how these treatments change appetite and metabolism.
New York, New YorkAges 18–45 - NCT05681988Recruiting
Minimally invasive endoscopic surgery for brain bleeding
This trial studies whether a minimally invasive, image-guided endoscopic procedure can remove blood after a specific type of brain bleed. It may help reduce symptoms and improve outcomes compared with standard care, but you must meet timing and medical criteria.
BaselAges 18–85 - NCT05681936Recruiting
Brain and spine scans after spinal cord injury or related conditions
This study uses brain and spine scans (and possibly nerve stimulation in some cases) to understand how the nervous system changes after spinal cord injury or certain spinal conditions. It may help researchers better track recovery and understand which changes are linked to symptoms like bladder problems.
ZurichAges 18 years+ - NCT05682677Recruiting
Brain stimulation plus cognitive training for depression after mild head injury
This study tests whether a combination of brain stimulation and cognitive training can reduce depression symptoms in people who have ongoing mild traumatic brain injury (TBI). It may help by targeting both mood and thinking/processing skills affected after mTBI.
La Jolla, CaliforniaAges 18–65 - NCT05683093Recruiting
Follow-up study for adults after hypertensive pregnancy
This study follows young adults who previously joined the ALSPAC study to better understand long-term heart and metabolic health after a pregnancy affected by high blood pressure. You may be asked to return for visits and possibly an MRI, and your data may help researchers plan better long-term care.
Oxford, OxfordshireAges 30–40 - NCT05683145Recruiting
Better sleep for people with moderate or severe TBI
This trial studies an approach to improve insomnia (trouble falling or staying asleep) in people who had a moderate-to-severe traumatic brain injury at least one year ago. If you qualify, it may help you restore more regular, efficient sleep after TBI.
Aurora, ColoradoAges 18–60 - NCT05683418RecruitingPhase 1
Study of a new drug for PIK3CA-mutated HR+ HER2- breast cancer
This early-stage study tests the safety and tolerability of TOS-358 in women with HR-positive, HER2-negative breast cancer that has a specific gene change (PIK3CA). It may help learn whether this targeted treatment is safe enough to move forward.
Chicago, IllinoisAges 18 years+ - NCT05683873Recruiting
Study of heart stress after stroke using a blood marker
This study looks at how heart function changes soon after a new stroke, and whether a blood marker called GDF-15 can help explain or predict that change. It may help doctors better monitor heart stress after stroke and tailor care sooner.
DijonAges 18 years+ - NCT05685069Recruiting
Studying stroke risk factors in people with silent brain infarcts
This study looks for what may have caused “silent” mini-strokes in the brain that were found on MRI, and which risk factors might be changeable. It may help doctors better understand how to prevent future stroke in people who have no clear stroke symptoms from the finding.
ToursAges 16 years+ - NCT05686473Recruiting
Parent teaching program for children with prenatal alcohol exposure
This study offers a structured teaching program for parents of children who were exposed to alcohol before birth (prenatal alcohol exposure). It aims to help families better understand the child’s needs and how to support development and daily functioning.
ArendalAges 2–18 - NCT05686642RecruitingPhase 2
Drug LT3001 for sudden stroke symptoms within 24 hours
This Phase 2 study tests LT3001 to improve recovery after an acute ischemic stroke (a stroke caused by blocked blood flow). It is designed for people who can be treated within 24 hours of symptom onset and who meet specific safety and health requirements.
Beijing, Beijing MunicipalityAges 18–80 - NCT05686798RecruitingPhase 1
Gene therapy plus radiation for recurring brain tumor
This early-phase study tests a “suicide gene” therapy delivered by a virus along with radiation for adults whose high-grade brain tumor has come back or grown again. The goal is to see if the treatment is safe and can help control the tumor.
Detroit, MichiganAges 18 years+ - NCT05688683Recruiting
Brain recording during awake surgery to study motor learning
This study uses special brain recordings during an awake surgical procedure to understand how the brain learns new movement and sensation skills. If you can comfortably take part in a simple task during surgery, you may help researchers learn how learning works in humans.
ParisAges 18 years+ - NCT05689619Recruiting
Silibinin after one brain metastasis surgery for lung or breast cancer
This trial studies silibinin, a natural substance, to help prevent brain metastasis from coming back after surgery. It is for people with lung (NSCLC) or breast cancer who have exactly one small brain metastasis that is fully removed and has a specific lab marker in the brain tissue.
GenovaAges 18–70 - NCT05689944Recruiting
Dance therapy for teens with chronic pain
This trial studies whether dance therapy can help reduce chronic pain in teens when usual pain treatments haven’t worked well. It may be helpful if you’re followed in a pain clinic and are able to participate in movement-based sessions.
BronAges 12–20 - NCT05690737Recruiting
Tai chi program to prevent episodic migraine
This trial tests whether a tai chi routine can help prevent episodic migraine attacks and reduce bothersome symptoms like nausea or light/sound sensitivity. It also looks at how tai chi may change the brain or body processes involved in migraine.
Hong Kong, HONG KONGAges 18–65 - NCT05691244RecruitingPhase 3
Tested drug for acute ischemic stroke within 24 hours
This Phase 3 trial studies sovateltide (and a placebo) in adults with an ischemic stroke, aiming to improve safety and outcomes. It focuses on people who can start treatment quickly after stroke symptoms begin and who do not have bleeding in the brain on imaging.
Tucson, ArizonaAges 18–80 - NCT05692635RecruitingPhase 2
Brain MRI checks to prevent lung cancer brain symptoms
This trial tests whether doing scheduled brain MRI scans can lower the chance that lung cancer later causes symptomatic brain metastases (tumors that cause symptoms in the brain). If you’re eligible, you’ll get brain MRI surveillance at a specific time after starting radiation.
Winston-Salem, North CarolinaAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,425 recruiting neurology studies from the U.S. registry right now, out of 19,436 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.