Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,425 recruiting studies in this area right now.
By phase
- Not applicable9,762
- Phase 2784
- Phase 1574
- Phase 3535
- Phase 4342
- Phase 1/Phase 2305
- Phase 2/Phase 3123
Top conditions
- Stroke845
- Parkinson Disease426
- Multiple Sclerosis343
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California678
- Massachusetts300
- New York292
- Florida275
- Texas267
- Maryland245
- Arizona213
- Alabama211
- Illinois189
- Pennsylvania178
Recruiting studies12,423 total
- NCT05793034Recruiting
Study factors that predict survival after aggressive meningioma surgery
This study looks at people who had surgery for more aggressive meningiomas (grade 2 or 3) and tries to learn what factors relate to survival. The results may help doctors better predict outcomes for future patients.
RomeAges 18 years+ - NCT05793177Recruiting
Monitoring light movement after stroke rehabilitation
This study checks whether tracking sitting time and light activity after stroke is helpful for recovery during rehabilitation. You would be monitored for daily movement, and the researchers want to see how activity patterns relate to recovery.
RoskildeAges Any age - NCT05794061Recruiting
Testing new ways to assess brain and behavior health
This study is developing and checking better tests to understand neurological (brain-related) and psychiatric (mental health) conditions. If you have a diagnosed brain or mental health condition—or you’re being considered as a healthy person—your results will help researchers see how well these assessments work.
Milan, LombardyAges 20–100 - NCT05794295Recruiting
Sleep study in people with focal epilepsy
This trial studies how sleep patterns relate to thinking and memory in people with focal epilepsy. It may help researchers understand what sleep changes could support brain function in epilepsy.
Sacramento, CaliforniaAges 18–40 - NCT05795634Recruiting
Study stress effects in people at risk for Alzheimer’s
This study looks at how stress may affect thinking and memory in people with mild cognitive impairment (MCI) who are at risk for Alzheimer’s disease. You may be asked to do thinking tests and also involve a knowledgeable person who can report on changes over time.
Baltimore, MarylandAges 60 years+ - NCT05795842Recruiting
Detecting atrial fibrillation after stroke using a wrist monitor
This study checks whether a special wrist device can detect an irregular heartbeat (atrial fibrillation) in people who recently had a stroke with an unclear cause. It may help doctors find the cause earlier and tailor follow-up care.
Atlanta, GeorgiaAges 55 years+ - NCT05795686Recruiting
Study of the AVanCer day-center support program for patients
This study looks at how a day-center support program (AVanCer) affects patients and their caregivers. If you join, you may complete questionnaires and help researchers understand your experiences through assessments in French.
BronAges 18 years+ - NCT05795738Recruiting
Training to help kindergarten kids learn better movement
This study tests a visual-and-movement training program for children as they start first grade. It may help kids improve how they use their eyes and body to do school tasks.
TainanAges 5–6 - NCT05797857Recruiting
Exercise program for transthyretin heart amyloidosis
This trial studies whether a structured exercise training program is safe and helpful for people with transthyretin (ATTR) cardiac amyloidosis. It may help improve fitness and daily functioning, and it may also compare groups for specific eligibility needs.
Boston, MassachusettsAges 60–90 - NCT05799001Recruiting
Dance workshops for seniors with dementia behavior changes
This trial tests whether structured dance sessions can help improve behavioral and emotional symptoms in people with dementia living in care facilities. It may help by offering a gentle, guided activity while keeping medications stable.
Craponne-sur-ArzonAges 65 years+ - NCT05799326Recruiting
Levofloxacin after sudden stroke to improve safety and recovery
This trial tests whether the antibiotic levofloxacin can be given soon after an acute ischemic stroke to improve outcomes and monitor side effects. It’s for people with a moderate stroke severity who are not having certain emergency treatments or infections.
Changchun, JilinAges 18–75 - NCT05800275RecruitingPhase 2
Tucatinib and capecitabine plus spinal trastuzumab for HER2+ cancer
This Phase 2 trial tests a combination of tucatinib and capecitabine (taken by mouth) plus trastuzumab delivered into the spinal fluid, to treat breast cancer that has spread to the leptomeninges (lining around the brain/spinal cord). It may help reduce cancer activity in the spinal fluid and improve symptoms.
BordeauxAges 18 years+ - NCT05800028Recruiting
Study brain scans and social life in memory changes
This study looks at how memory and brain function relate to social interactions. It focuses on people with probable Alzheimer’s disease or a specific language-related condition, and on healthy partners matched by age and social background.
CaenAges 18–85 - NCT05800470Recruiting
Brain-training with light sensors to improve walking in Parkinson’s
This trial tests a “neurofeedback” training program using a special light-sensing cap (fNIRS) to help improve balance and walking in people with Parkinson’s disease. You may also do guided walking practice mentally (imagery training), and your ability to walk and balance will be measured.
Taipei, None SelectedAges 40–85 - NCT05800535Recruiting
Screening for muscle loss and thinking changes after cancer
This study looks at how common muscle weakness (sarcopenia) and thinking or memory changes (often called “chemobrain”) are in people after cancer treatment. It may help teams understand what support could be most helpful after chemotherapy.
Pierre-BéniteAges 18–74 - NCT05800821Recruiting
Predicting brain blood-flow problems after carotid surgery
This study uses deep learning to predict which people are at risk for “cerebral hyperperfusion syndrome” (a dangerous spike in brain blood flow) after carotid revascularization. If you qualify, they’ll use scans/tests to estimate your risk so doctors can watch you more closely if needed.
MinskAges 30–80 - NCT05801380Recruiting
Tracking how well a medicine works in Alzheimer’s patients
This study looks at how effective a treatment is in people newly diagnosed with mild to moderate Alzheimer’s disease. It also involves health and medication history checks and likely stool (fecal) sample collection to monitor effects.
Manila, National Capital RegionAges 65 years+ - NCT05804084RecruitingPhase 2
Acetazolamide for sleep apnea: sleep and brain outcomes
This study tests acetazolamide (a medicine that changes breathing chemistry) to see how it affects sleep quality and neurocognitive (brain/memory/attention) outcomes in adults with untreated moderate to severe sleep apnea. You may be eligible if you have significant sleep apnea but do not have certain safety risks or need to start standard sleep apnea treatment right away.
La Jolla, CaliforniaAges 18 years+ - NCT05804448Recruiting
Altitude effect on spinal headache after C-section
This study looks at whether living at higher or lower altitudes changes the risk of a specific headache after a C-section done with spinal anesthesia. The goal is to understand who is more likely to get this headache so care can be better tailored.
Jumla, KarnaliAges 18 years+ - NCT05805384Recruiting
Testing a noise-reduction program for cochlear implant users
This trial checks how well a computer “noise reduction” algorithm works for people who use cochlear implants. It may help make speech easier to understand in noisy settings.
New York, New YorkAges 12 years+ - NCT05805631RecruitingPhase 2
Pemetrexed into spinal fluid for EGFR-mutant lung cancer spread to brain lining
This Phase 2 trial tests giving pemetrexed directly into the spinal fluid to treat cancer that has spread to the brain’s and spinal cord’s lining (leptomeningeal metastasis). It is for people with EGFR-mutant non-squamous lung cancer whose disease progressed after osimertinib, and who may benefit from a targeted treatment delivered to the area affected in the brain lining.
Taipei, TaiwanAges 20 years+ - NCT05805683Recruiting
Calcitonin for nerve pain after spinal cord injury
This study tests whether calcitonin can prevent or lessen nerve pain after a spinal cord injury. It may help reduce how often neuropathic (nerve-type) pain happens and how severe it becomes.
Tanta, Gharbia GovernorateAges 18 years+ - NCT05806697Recruiting
Study of brain scan clues in people worried about memory
This extension study looks for predictors—measurable clues—linked to memory changes in older adults who feel their memory is worsening. You may be asked to have an amyloid PET scan, which can help researchers understand what might be driving memory concerns.
Paris, Île-de-France RegionAges 70–95 - NCT05807321Recruiting
Biofeedback therapy for bowel coordination problems
This trial tests a biofeedback therapy program (training using feedback to improve bowel movements) for people with bowel coordination problems called dyssynergia. It may help you learn techniques that make passing stool easier and more predictable.
San Diego, CaliforniaAges 21–75
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,425 recruiting neurology studies from the U.S. registry right now, out of 19,436 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.