Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 11,975 recruiting studies in this area right now.
By phase
- Not applicable9,368
- Phase 2765
- Phase 1561
- Phase 3516
- Phase 4338
- Phase 1/Phase 2301
- Phase 2/Phase 3126
Top conditions
- Stroke799
- Parkinson Disease395
- Alzheimer Disease339
- Multiple Sclerosis330
- Dementia227
- Epilepsy194
- Ischemic Stroke190
- Insomnia159
- Traumatic Brain Injury151
- Obstructive Sleep Apnea142
- Spinal Cord Injuries142
- Acute Ischemic Stroke140
- Sarcopenia134
- Mild Cognitive Impairment129
- Cerebral Palsy120
- Pain Management116
- Migraine107
- Fibromyalgia104
Leading sponsors
- Beijing Tiantan Hospital125
- Assistance Publique - Hôpitaux de Paris110
- Riphah International University105
- Mayo Clinic98
- VA Office of Research and Development91
- Xuanwu Hospital, Beijing89
- Hospices Civils de Lyon77
- Johns Hopkins University70
- University of Minnesota63
- Washington University School of Medicine63
Where studies are running
- California662
- Massachusetts306
- New York296
- Florida272
- Texas267
- Maryland249
- Alabama206
- Arizona206
- Illinois181
- Pennsylvania177
Recruiting studies11,975 total
- NCT07281313Recruiting
Exercise for aphasia after stroke
This trial tests whether a regular exercise program can help people with aphasia (trouble speaking or understanding language) after a stroke. It focuses on safety and improving language and physical health.
Berkeley, CaliforniaAges 18–80 - NCT07287527Recruiting
Light therapy for memory and brain health
This study tests whether a type of light therapy called photobiomodulation can improve brain connections and thinking abilities in people with mild memory problems.
IstanbulAges 55 years+ - NCT07283289Recruiting
Obstructive sleep apnea in patients with PAD
This study looks at how common obstructive sleep apnea is in people with peripheral artery disease (PAD). Participants will have a sleep test as part of their regular care.
Toulon, VarAges 18 years+ - NCT07286435Recruiting
Vibration therapy after botox for stroke spasticity
This trial tests if adding whole-body vibration therapy to botulinum toxin A (Botox) injections can improve muscle stiffness, balance, and walking in stroke survivors. It may help reduce spasticity and make daily activities easier.
Bursa, BursaAges 18–75 - NCT07281794Recruiting
Testing a wearable system for walking and balance in Parkinson's
This study tests a wearable system (DANU Sports) that measures how you walk and keep your balance. It aims to see if the system can help people with Parkinson's disease track their movement problems.
Newcastle upon Tyne, Tyne and WearAges 50 years+ - NCT07284719Recruiting
Focused Ultrasound for Parkinson's Tremor
This trial tests a non-invasive treatment called MR-guided focused ultrasound (MRgFUS) to reduce severe tremor in Parkinson's disease. It uses sound waves to target the brain area causing the shaking, without surgery.
AarhusAges 50–80 - NCT07285837Recruiting
Intensive arm rehab for kids with cerebral palsy
This study tests an intensive rehabilitation program for the upper limb (arm and hand) in children and teens with cerebral palsy. It aims to improve arm function and may help your child gain more control and independence.
Saint-Fargeau-Ponthierry, Île-de-France RegionAges 3–17 - NCT07280416Recruiting
Sleep changes in first year after cancer diagnosis
This study follows people who are newly diagnosed with cancer to see how their sleep changes during the first year. It looks at whether treatments like chemo or immunotherapy affect insomnia.
Le Puy-en-VelayAges 18–80 - NCT07282938Recruiting
Robot hand and electrical stimulation for hand function after stroke
This test combines a soft robotic hand and electrical stimulation to help improve hand movement in people recovering from a stroke. It may benefit stroke survivors who have some ability to extend their fingers and are in the early months of recovery.
Lahore, Punjab ProvinceAges 45–65 - NCT07285226Recruiting
Creatine for muscle loss in older adults
This trial tests whether taking creatine HCl can help older adults with muscle loss (sarcopenia) improve muscle strength. If you are over 60 and have weak grip strength, this study might be for you.
BelgradeAges 60 years+ - NCT07281118Recruiting
Nerve freezing for pain after double lung transplant
This trial tests a procedure called intercostal cryoanalgesia, which freezes nerves in the chest to reduce pain after a double lung transplant. It may help you feel less pain and use fewer painkillers after surgery.
Los Angeles, CaliforniaAges 18 years+ - NCT07287215Recruiting
Motor imagery and daily function in diplegic cerebral palsy
This study tests whether imagining movements (motor imagery) can help improve everyday skills like walking and playing in children with diplegic cerebral palsy. It compares the effects of motor imagery training with standard physical therapy.
BingoelAges 5–18 - NCT07280468RecruitingPhase 4
Personalized sleep apnea treatment for Down syndrome
This study tests if a treatment chosen based on your specific type of sleep apnea works better for people with Down syndrome. It looks for participants who have sleep apnea but are not already using a CPAP machine regularly.
Tucson, ArizonaAges 6 years+ - NCT07287605Recruiting
Virtual reality for mood during focused ultrasound for essential tremor
This study tests if using virtual reality can improve your mood while you undergo a focused ultrasound procedure for essential tremor. If you are already scheduled for this treatment, you may be able to join.
North York, OntarioAges 18 years+ - NCT07287774Recruiting
Testing a new noise-reduction feature for hearing aids
This trial is testing a new computer program that helps hearing aids reduce background noise. It might make it easier for people with mild to moderate hearing loss to hear in noisy places.
West Lafayette, IndianaAges 18 years+ - NCT07283276Recruiting
Core training vs cognitive training for ankle instability
This study tests whether special core exercises or mental training can help improve your balance and control after repeated ankle sprains. If you have chronic ankle instability, this could help you find which type of training works best.
CairoAges 18–30 - NCT07281651Recruiting
Understanding pain sensitivity in knee pain and fibromyalgia
This study looks at how the brain and nerves process pain in people with knee pain or fibromyalgia. It compares them to pain-free people to understand differences in muscle signals.
Derby, DerbyshireAges 40 years+ - NCT07279740RecruitingPhase 2
Brain stimulation plus medication for apathy in dementia
This study tests if combining a type of brain stimulation (repetitive TMS) with a medication (methylphenidate, commonly used for ADHD) can improve apathy in people with dementia. If you have Alzheimer's or mixed dementia and struggle with low motivation, this trial may help you.
Toronto, OntarioAges Any age - NCT07282691Recruiting
Validating eye tests for mild brain injury
This study looks at eye tests for people who had a mild brain injury (mTBI) in the last 1 to 6 months. It aims to better understand and measure eye movement problems that can happen after such an injury.
Philadelphia, PennsylvaniaAges 18–35 - NCT07281846Recruiting
TIPS with or without BCAA for cirrhosis and muscle wasting
This trial tests whether adding branched-chain amino acids (BCAA) to the standard TIPS procedure helps people with cirrhosis and muscle wasting. It aims to see if BCAA can improve outcomes after TIPS.
WuhanAges 18–80 - NCT07284732Recruiting
Ear nerve stimulation for consciousness disorders
This trial tests whether a gentle electrical stimulation on the ear can help people with disorders of consciousness, like a vegetative or minimally conscious state. It aims to see if this noninvasive treatment can improve brain function and awareness.
Guangzhou, GuangdongAges 18–70 - NCT07279259RecruitingPhase 2
Blood pressure management after stroke clot-dissolving treatment
This trial tests how managing high blood pressure during clot-dissolving treatment for acute ischemic stroke affects recovery. It is for patients who have high blood pressure at the start of treatment.
ShanghaiAges 18–80 - NCT07280351Enrolling by invitation
Duraplasty for acute spinal cord injury
This trial tests whether adding a special patch (duroplasty) during emergency spinal surgery helps people recover from a recent traumatic spinal cord injury. It's for patients who need decompression surgery within 24 hours of injury.
San Francisco, CaliforniaAges 18–80 - NCT07280195Enrolling by invitationPhase 4
Comparing pain relief after shoulder replacement
This study compares two ways to manage pain after shoulder replacement surgery: a long-acting numbing medicine (ZYNRELEF) versus a temporary nerve block catheter. It aims to see which provides better pain control and recovery.
St Louis, MissouriAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 11,975 recruiting neurology studies from the U.S. registry right now, out of 18,541 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.