Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,435 recruiting studies in this area right now.
By phase
- Not applicable9,772
- Phase 2786
- Phase 1573
- Phase 3535
- Phase 4342
- Phase 1/Phase 2304
- Phase 2/Phase 3123
Top conditions
- Stroke846
- Parkinson Disease426
- Multiple Sclerosis343
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke200
- Epilepsy196
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California680
- Massachusetts300
- New York291
- Florida274
- Texas268
- Maryland245
- Arizona214
- Alabama209
- Illinois190
- Pennsylvania177
Recruiting studies12,433 total
- NCT06181149Recruiting
Stuttering and how the brain predicts speech sounds
This study uses brain imaging and stimulation to understand how people who stutter process speech sounds. It may help explain why stuttering happens and guide future treatments.
Tempe, ArizonaAges 3 years+ - NCT06181513RecruitingEarly Phase 1
Probiotics for mild Alzheimer's disease
This study tests whether daily probiotics (beneficial bacteria) can help people with mild Alzheimer's disease. It's an early-phase trial to see if probiotics are safe and might improve thinking and memory.
NicosiaAges 65–85 - NCT06181994Recruiting
Middle meningeal artery embolization for chronic subdural hematoma
This trial looks at how well a procedure called middle meningeal artery embolization works for people with chronic subdural hematoma (a collection of old blood on the brain's surface). It uses specific materials to block the blood supply to the hematoma, which may help the body reabsorb it without surgery.
Coral Gables, FloridaAges 18 years+ - NCT06183528Recruiting
Numbing shot for recovery after hip replacement
This study looks at a special numbing shot around the hip joint to see if it helps people recover faster and feel better after total hip replacement surgery. It may help reduce pain and improve your recovery.
Istanbul, UmraniyeAges 40–85 - NCT06183658Recruiting
Healthy Brain Aging Study for Adults 55–90
This study looks at healthy brain aging in older adults. It involves brain scans, blood tests, and regular check-ins to understand how memory and thinking change over time.
Shenzhen, OtherAges 55–90 - NCT06183645Recruiting
Predicting CIDP decline during IVIg treatment changes
This study looks at people with CIDP who are stable on IVIg treatment to see if we can predict when they might get worse if their treatment is adjusted. It aims to make treatment management easier and more personalized.
Liège, LiègeAges 18–99 - NCT06184295Recruiting
Robotic balance training for better balance after brain injury
This study tests whether training on a robotic device can help improve balance and posture for people who had a traumatic brain injury (TBI) within the last 6 months to 5 years. It may help if you have some balance issues and can stand without support for 5 minutes.
West Orange, New JerseyAges 18–65 - NCT06184945Recruiting
Study of ICU staffing and support strategies
This study looks at how different staffing and support strategies may help patients who need a breathing machine in the ICU. Researchers want to see if these approaches can improve care and recovery.
Iowa City, IowaAges 19 years+ - NCT06185179RecruitingEarly Phase 1
Metformin for muscle recovery in older adults
This study tests whether a common diabetes medicine called metformin can help your muscles recover faster after a minor injury. You may qualify if you are 60 or older, generally healthy, and not taking certain medicines.
Salt Lake City, UtahAges 60 years+ - NCT06185686Recruiting
Brain Network Changes in Kids with Brain Tumors After Proton Radiation
This study looks at how proton radiation affects brain networks in children and teens with brain tumors. It uses MRI scans and computer tasks to understand changes in the brain during and after treatment.
St Louis, MissouriAges 8–21 - NCT06185673RecruitingPhase 1/Phase 2
Gene therapy trial for OPMD with swallowing problems
This trial tests an experimental gene therapy (BB-301) for people with OPMD who have trouble swallowing. It involves a one-time injection into the throat muscles during a short surgery, and researchers will check if it is safe and improves swallowing.
New York, New YorkAges Up to 65 years - NCT06187012Recruiting
Long-term heart health after pregnancy
This study checks if having high blood pressure years after pregnancy is linked to long-term health. It involves a visit and possibly an MRI scan of your heart and blood vessels.
OxfordAges 30–70 - NCT06187025Recruiting
Addiction & Stroke: Smartphone tool for prevention
This study tests whether a smartphone tool can help people who have had a stroke make healthier choices to prevent another one. It specifically looks at how the tool might help manage addiction-related risks.
BordeauxAges 18–80 - NCT06187467Recruiting
Understanding balance and walking after a first stroke
This study tracks how balance and walking change over time after a first stroke, using simple tests and wearable sensors. It may help find better ways to help you recover your ability to walk safely.
Singapore, SingaporeAges 21–85 - NCT06188364RecruitingEarly Phase 1
Helping caregivers of traumatic brain injury patients
This trial tests if mobile health support (texts and calls) helps caregivers of people with traumatic brain injury after rehab. You may join as the main caregiver if you supervise daily care and have a smartphone or can get one.
Richmond, VirginiaAges 18 years+ - NCT06188741RecruitingPhase 2
Selumetinib to prevent tumor growth in NF1 children
This study tests whether the drug selumetinib can prevent the growth of plexiform neurofibromas (nerve tumors) in young children with NF1. Children are first monitored with MRI scans, and if a tumor appears or grows, they may receive treatment.
Birmingham, AlabamaAges 1–8 - NCT06189755Recruiting
MicroRNA markers for sleep apnea
This trial is studying tiny molecules in the blood (called microRNAs) to see if they can help diagnose or monitor obstructive sleep apnea. It compares people with moderate to severe sleep apnea who are starting PAP therapy with people who do not have sleep apnea.
Columbus, OhioAges 18–75 - NCT06189781RecruitingPhase 4
Pain shot vs epidural for hip surgery in kids with cerebral palsy
This study compares a pain injection to epidural anesthesia for children with cerebral palsy having hip surgery. The goal is to see which method provides better pain control during and after the procedure.
Los Angeles, CaliforniaAges Up to 18 years - NCT06189950Recruiting
Testing a new stent for wide-necked brain aneurysms
This trial is testing a new stent (a small mesh tube) designed to treat wide-necked brain aneurysms. If you have this type of aneurysm, the stent helps hold coils in place to block blood flow and prevent rupture.
Zhengzhou, HenanAges 18–80 - NCT06191198RecruitingPhase 2
Communication Bridge 3: Speech therapy for PPA
This study tests a web-based speech therapy program called Communication Bridge for people with Primary Progressive Aphasia (PPA) and their communication partners. The goal is to improve communication skills and quality of life.
Chicago, IllinoisAges 18–100 - NCT06190431Recruiting
Can coaching help kids learn to use a lung-clearing device?
This study tests whether a coaching feature helps children learn to use a device called mechanical in-exsufflation (MI-E), which helps clear mucus from the lungs. The trial is split into two parts: one for healthy children and one for children with neuromuscular diseases.
Brussels, Brussels CapitalAges 6–12 - NCT06190626Recruiting
A study of eye disease in Zellweger spectrum disorder over time
This study follows people with Zellweger spectrum disorder (ZSD) to understand how their eye condition develops over time. It aims to help doctors treat the disease better in the future.
Rochester, New YorkAges Any age - NCT06191640Recruiting
Study of sinus disease in young children with cystic fibrosis
This study looks at sinus problems in young children with cystic fibrosis. One group of children starts a new medicine called a highly effective modulator (like Trikafta), and the other group does not take this medicine. The goal is to see how the medicine affects sinus health over time.
Aurora, ColoradoAges 2–8 - NCT06192576Recruiting
Long-term safety of olipudase alfa in young children with ASMD
This study looks at the long-term safety and how well the body accepts olipudase alfa therapy in children under 2 years old who have a certain type of ASMD. It helps understand if the treatment works safely over time.
Chicago, IllinoisAges Up to 2 years
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,435 recruiting neurology studies from the U.S. registry right now, out of 19,491 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.