Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,435 recruiting studies in this area right now.
By phase
- Not applicable9,772
- Phase 2786
- Phase 1573
- Phase 3535
- Phase 4342
- Phase 1/Phase 2304
- Phase 2/Phase 3123
Top conditions
- Stroke846
- Parkinson Disease426
- Multiple Sclerosis343
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke200
- Epilepsy196
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California680
- Massachusetts300
- New York291
- Florida274
- Texas268
- Maryland245
- Arizona214
- Alabama209
- Illinois190
- Pennsylvania177
Recruiting studies12,433 total
- NCT06167681RecruitingPhase 1/Phase 2
Cell Therapy NouvNeu001 for Parkinson's Disease
This trial tests a new cell therapy called NouvNeu001 for Parkinson's disease. It involves a one-time brain surgery to deliver the treatment, and researchers will check if it's safe and helps with symptoms.
Beijing, Beijing MunicipalityAges 50–75 - NCT06168604Recruiting
Pain communication toolkit for dementia caregivers
This trial tests a toolkit to help caregivers of adults with dementia and chronic pain better identify and communicate about their loved one's pain. You and the person you care for may join if you meet the listed requirements.
New York, New YorkAges 21 years+ - NCT06169150Recruiting
Studying nervous system issues in immune disorders
This study looks for and tracks nervous system problems in people with immune system disorders. It aims to better understand how infections or inflammation affect the brain and nerves in these patients.
Bethesda, MarylandAges 2–120 - NCT06169852Recruiting
Brain signal study during DBS surgery for Parkinson's
This study looks at brain signals during awake deep brain stimulation (DBS) surgery for Parkinson's disease. The goal is to learn how these signals can help guide the placement of electrodes to improve treatment.
Birmingham, AlabamaAges 18–89 - NCT06169046RecruitingPhase 2
Clenbuterol for spinal and bulbar muscular atrophy
This study tests if clenbuterol (a medication that may help strengthen muscles) can improve symptoms in people with spinal and bulbar muscular atrophy (SBMA, also called Kennedy's disease). It compares clenbuterol to a placebo (a dummy pill) over several months.
Padova, PDAges 18–75 - NCT06170268Recruiting
Alzheimer's registry for treatment and diagnosis
This registry collects information from people with mild cognitive impairment or dementia due to Alzheimer's disease who are being treated with new FDA-approved therapies. The goal is to track how these treatments work in everyday medical practice.
Chicago, IllinoisAges 18 years+ - NCT06170645Recruiting
Vagus nerve stimulation for fatigue in fibromyalgia or long COVID
This trial tests whether a gentle electrical stimulation device on the ear (vagus nerve) can help reduce fatigue when combined with exercise. It is for people with fibromyalgia or long COVID who still feel exhausted after a rehab program.
Saint-EtienneAges 18 years+ - NCT06170970RecruitingPhase 2
Solriamfetol for fatigue in multiple sclerosis
This study tests whether solriamfetol, a medication that promotes wakefulness, can reduce fatigue in people with multiple sclerosis. If you struggle with tiredness and sleepiness, this trial may help you understand how this drug works for MS-related fatigue.
Baltimore, MarylandAges 18–60 - NCT06170944Recruiting
Stroke recovery: Testing blood flow boost therapy
This study tests a simple, non-invasive treatment called remote ischemic preconditioning. It uses a blood pressure cuff on your arm to temporarily restrict blood flow, which may help improve blood flow to the brain after a stroke. The goal is to see if this can strengthen the brain's backup blood vessels and aid recovery.
ShenyangAges 40 years+ - NCT06172491Recruiting
Automated tool to measure ICU delirium severity
This study tests a computerized tool that automatically measures how severe delirium (sudden confusion) is for ICU patients. Researchers want to see if it can help monitor and manage delirium better without adding extra work for nurses.
Rochester, MinnesotaAges 50 years+ - NCT06172621Recruiting
Spinal cord stimulation study for ALS hand weakness
This study tests whether combining brain and spinal cord stimulation can improve hand function in people with ALS who have partial weakness but still some movement in their fingers. The goal is to see if this non-invasive approach can strengthen nerve connections.
The Bronx, New YorkAges 18–80 - NCT06172101Recruiting
Fat flap surgery for recurrent thoracic outlet syndrome
This trial tests whether using a free fat flap during repeat surgery for neurogenic thoracic outlet syndrome can improve outcomes. It may help patients who have had symptoms come back after their first surgery.
NantesAges 18 years+ - NCT06173076Recruiting
Study of outcomes in anti-LGI1 brain inflammation
This study follows people newly diagnosed with anti-LGI1 encephalitis (a brain inflammation) to see how well they do over time. It aims to learn more about the condition and improve care.
Hangzhou, ZhejiangAges 18–100 - NCT06174038Recruiting
Hearing aids for memory and hearing loss study
This study tests whether hearing aids can help people with both hearing loss and early memory problems. It lasts for a period of time, and you will be asked to wear hearing aids daily.
New York, New YorkAges 55–75 - NCT06174948Recruiting
CUE1 device for Parkinson's and related movement disorders
This trial tests a small device called CUE1 that gives gentle vibrations on the chest to help improve movement and balance in people with Parkinson's disease and similar conditions. It may help if you have trouble with walking or stability.
LondonAges 18 years+ - NCT06175715Recruiting
General vs. local anesthesia for carotid artery surgery after stroke
This trial compares two types of anesthesia for people who need surgery to clean out a blocked carotid artery after a recent stroke. It aims to see which anesthesia method leads to better recovery after the surgery.
MoscowAges 40–80 - NCT06176144Recruiting
Comparing two anesthetics for confusion after surgery in older adults
This trial compares two types of anesthesia (desflurane and sevoflurane) to see if one causes less confusion after surgery in older adults. It may help if you are 65 or older and having a non-heart, non-brain surgery lasting at least 2 hours.
Chengdu, SichuanAges 65–90 - NCT06177990Recruiting
Online skills training for caregivers of people with Alzheimer's
This study tests an online program to help family caregivers develop navigation skills for supporting a loved one with Alzheimer's or related dementias. It aims to reduce caregiver stress and improve care coordination.
Atlanta, GeorgiaAges 18 years+ - NCT06176989RecruitingPhase 2
Enasidenib for IDH2-mutated sinonasal and skull base tumors
This trial tests an oral targeted therapy called enasidenib for people with rare head and neck cancers that have an IDH2 gene mutation. The goal is to see if this drug can shrink or slow the growth of these tumors.
Bethesda, MarylandAges 18–120 - NCT06177509Recruiting
Exercise therapy for mild traumatic brain injury
This trial tests if graded aerobic exercise can help people who have ongoing symptoms after a mild traumatic brain injury (concussion). It aims to see if carefully increasing exercise intensity improves tolerance to physical activity.
NesoddtangenAges 18–60 - NCT06178120Recruiting
Study of disease progression in women with X-linked adrenoleukodystrophy
This study follows women with a genetic condition called X-linked adrenoleukodystrophy (ALD) over time to see how the disease progresses. It includes annual check-ups and MRI scans of the brain and spinal cord to monitor changes.
ParisAges 18 years+ - NCT06178419Recruiting
Remote Conditioning for Brain Ischemia in Takayasu Arteritis
This trial tests whether gentle, repeated blood pressure cuff inflations on the arm can improve blood flow to the brain in people with Takayasu arteritis. It's for those with inactive disease and narrowed brain arteries but who still have low brain blood flow.
Beijing, Beijing MunicipalityAges 18–65 - NCT06179680Recruiting
White matter changes in memory problems or Alzheimer's
This study uses brain MRI scans to look at white matter changes in people with memory problems (amnestic mild cognitive impairment) or Alzheimer's disease. It aims to understand how these changes relate to memory loss.
San Donato Milanese, MilanoAges 65 years+ - NCT06180291Recruiting
Early parent-professional help for babies at risk of cerebral palsy
This trial tests a program that helps parents and healthcare professionals work together from the start to support babies with certain brain injuries that can lead to cerebral palsy. It may help improve your baby's development through early, coordinated care.
AnnecyAges Up to 3 months
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,435 recruiting neurology studies from the U.S. registry right now, out of 19,491 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.