Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,435 recruiting studies in this area right now.
By phase
- Not applicable9,772
- Phase 2786
- Phase 1573
- Phase 3535
- Phase 4342
- Phase 1/Phase 2304
- Phase 2/Phase 3123
Top conditions
- Stroke846
- Parkinson Disease426
- Multiple Sclerosis343
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke200
- Epilepsy196
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California680
- Massachusetts300
- New York291
- Florida274
- Texas268
- Maryland245
- Arizona214
- Alabama209
- Illinois190
- Pennsylvania177
Recruiting studies12,433 total
- NCT06192953Recruiting
Early movement therapy after stroke
This trial tests a type of therapy that uses gentle movements and pressure to help your brain and body recover after a stroke. It's for people who recently had a stroke and have weakness on one side, and you will be asked to do special exercises guided by a therapist.
NiceAges 18–100 - NCT06192615RecruitingPhase 3
Can a sleep medication protect the brain after heart surgery?
This study tests whether a medicine called dexmedetomidine, given after heart surgery, can help prevent confusion and thinking problems in older adults during their intensive care stay. If you are 60 or older and having heart surgery with a heart-lung machine, this trial might be for you.
Los Angeles, CaliforniaAges 60 years+ - NCT06193759RecruitingPhase 1
Immune cell therapy for malignant pediatric brain tumors
This trial tests a new immune therapy using your child's own specially trained white blood cells to fight brain tumors. The treatment is given directly into the fluid around the brain, and it is for children with specific types of brain cancer.
Washington D.C., District of ColumbiaAges 1–30 - NCT06194539Recruiting
Fertility in Men with Spinal Muscular Atrophy
This study looks at fertility (the ability to have children) in men with spinal muscular atrophy (SMA). It will help doctors understand how SMA affects male fertility by tracking sperm health and related factors.
Cresskill, New JerseyAges 18–50 - NCT06194669Recruiting
VHL disease and kidney tumor risk study
This study looks at how early changes in kidney cells can lead to tumors in people with VHL disease. It may help understand why some people develop kidney cancer and how to prevent it.
MilanAges 18 years+ - NCT06194747Recruiting
Improving treatment speed for severe seizures in kids
This trial tests a faster way to give seizure-stopping medicine to children having a long or repeated seizure. The goal is to see if quicker treatment leads to better outcomes.
Columbus, OhioAges 4 weeks–18 years - NCT06194968Recruiting
Stroke treatment with urokinase in real-world settings
This study looks at how well the clot-busting drug urokinase works for treating acute ischemic stroke in everyday medical practice. It may help if you have had a stroke and are eligible for clot-dissolving medication.
Lanzhou, GansuAges 18 years+ - NCT06194929RecruitingPhase 1/Phase 2
Drug combo for melanoma that spread to the brain
This trial tests a combination of two or three drugs (defactinib, avutometinib, with or without encorafenib) to shrink brain tumors that started from skin melanoma. It may be an option for people whose melanoma has a specific genetic change and who have already tried immunotherapy.
Iowa City, IowaAges 18 years+ - NCT06195241RecruitingPhase 4
DaxibotulinumtoxinA for eyelid and facial spasms
This trial tests a new type of botulinum toxin (DaxibotulinumtoxinA) for people with eyelid or facial muscle spasms. It aims to see if it works better or lasts longer than current treatments.
The Bronx, New YorkAges 18 years+ - NCT06195345Recruiting
Brain oxygen study for children having an MRI
This study looks at oxygen levels in the brains of children and young adults (birth to 18 years) during a standard MRI. The goal is to learn more about how the brain works, and it only adds a few minutes to your child's regular MRI scan.
Los Angeles, CaliforniaAges 1 minute–18 years - NCT06195501Recruiting
Swallowing after heart ultrasound in acute stroke: follow-up study
This study follows stroke patients who get a TEE (a heart ultrasound through the mouth) to see how often swallowing problems occur after the procedure. If you qualify, researchers will check your swallowing to better understand and manage any risks.
Giessen, HesseAges 18 years+ - NCT06195800Recruiting
Biomarkers after stem cell transplant for neurological diseases
This trial looks at biomarkers (biological signs in your blood) in people with immune-mediated neurological diseases. It compares those getting a stem cell transplant to those on high-efficacy MS treatments to understand how these therapies work.
Sheffield, EnglandAges 16 years+ - NCT06196047RecruitingPhase 3
Ticagrelor vs cilostazol for minor stroke or TIA
This study compares two blood thinner medicines, ticagrelor and cilostazol, to see which is better at preventing another stroke in people who have just had a minor stroke or TIA (a mini-stroke). It is for people who started treatment within 24 hours of their symptoms.
Kafr ash ShaykhAges 18–75 - NCT06196229Recruiting
Virtual reality video therapy for arm recovery after stroke
This study tests whether watching virtual reality videos of arm movements can help improve arm function after a stroke. It may be a good fit if you have some movement in your affected arm and can follow instructions.
Lahore, Punjab ProvinceAges 40–60 - NCT06197165Recruiting
Shiatsu for amyloidosis symptoms and quality of life
This study tests whether shiatsu (a gentle Japanese touch therapy) can improve symptoms and quality of life for people with amyloidosis. If you have a bothersome symptom like pain, shortness of breath, or anxiety, this trial may help you feel better.
CréteilAges 18 years+ - NCT06197698Recruiting
Parkinson's and gut-brain connection study
This study is looking at how the bacteria in your gut might affect your brain in Parkinson's disease. It involves two types of brain scans to see differences between people with Parkinson's and healthy volunteers.
DouliuAges 20 years+ - NCT06198699Recruiting
Herbal tea for dementia patients and caregivers
This trial tests whether drinking Jing Si Herbal Tea can improve sleep and life quality for people with dementia and their caregivers. If you or someone you care for has dementia, you may join together.
Hualien CityAges 20 years+ - NCT06199856Recruiting
Ultrasound check for age-related muscle loss
This study uses an ultrasound (a painless scan) to check for sarcopenia—age-related muscle loss. It may be a good fit if you're over 50 and have noticed trouble with walking, climbing, or recent falls or weight loss.
Chengdu, SichuanAges Up to 100 years - NCT06200753Recruiting
Late stroke treatment study for large vessel blockages
This study looks at patients who had an ischemic stroke (a type of stroke caused by a blood clot) more than 24 hours ago and have a blockage in a large brain artery. It compares outcomes for those who get a procedure to remove the clot versus those who get only medical treatment.
Tianjin, Tianjin MunicipalityAges Any age - NCT06201598Recruiting
Treatment for brain aneurysms with flow-diverter stents
This study is testing if a type of stent called a flow-diverter is safe and effective for treating brain aneurysms. It may help patients who have an aneurysm that was found by chance, is causing symptoms, or has already ruptured.
A CoruñaAges 18 years+ - NCT06201897RecruitingPhase 2/Phase 3
Brain excitability in West syndrome using magnetic stimulation
This trial studies brain electrical activity in children with West syndrome (infantile spasms) using a safe, non-invasive magnetic stimulation technique. It tests how the brain responds before and after starting ACTH or a ketogenic diet, which are standard treatments for infantile spasms.
New Delhi, National Capital Territory of DelhiAges 6 months–2 years - NCT06202755RecruitingPhase 3
Comparing ticagrelor and cilostazol for large-vessel stroke
This trial compares two antiplatelet drugs (ticagrelor and cilostazol) to see which is better at preventing another stroke in people who have had a large-vessel ischemic stroke. Both drugs help keep blood clots from forming, and the study aims to find the safest and most effective option for patients who cannot receive clot-busting medication.
Kafr ash ShaykhAges 18–75 - NCT06202976Recruiting
Mapping epilepsy networks with brain imaging
This trial uses advanced brain imaging to map the networks causing seizures in children with certain types of epilepsy. The goal is to better understand where seizures start so doctors can plan more targeted treatments.
ParisAges Up to 18 years - NCT06203106Recruiting
NYSCF Scientific Discovery Biobank
This study collects blood, saliva, or skin samples from people with certain neurological conditions and from healthy volunteers to help researchers better understand and find treatments for these diseases.
New York, New YorkAges 4 weeks+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,435 recruiting neurology studies from the U.S. registry right now, out of 19,491 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.