Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,435 recruiting studies in this area right now.
By phase
- Not applicable9,772
- Phase 2786
- Phase 1573
- Phase 3535
- Phase 4342
- Phase 1/Phase 2304
- Phase 2/Phase 3123
Top conditions
- Stroke846
- Parkinson Disease426
- Multiple Sclerosis343
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke200
- Epilepsy196
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California680
- Massachusetts300
- New York291
- Florida274
- Texas268
- Maryland245
- Arizona214
- Alabama209
- Illinois190
- Pennsylvania177
Recruiting studies12,433 total
- NCT06221553RecruitingPhase 1
New CAR T-cell treatment for DIPG brain tumor
This trial tests a new type of immunotherapy called B7H3 IL-7Ra CAR T-cells for children with DIPG, a tough-to-treat brain tumor. The treatment is given directly into the fluid around the brain using a special catheter, and the goal is to see if it's safe and if it can help fight the tumor.
Bangkok, PathumwanAges 1–18 - NCT06221332Recruiting
Sacral block for pain control during normal birth
This trial studies a new pain-block method called the sacral erector spinae plane block, given along with your epidural during labor. It is for first-time mothers having a planned vaginal birth, and aims to see if it gives better pain relief.
KonyaAges 18–42 - NCT06221631Recruiting
Brain aging in MS and healthy people
This study compares how the brain ages in people with multiple sclerosis (MS) and healthy volunteers. It uses MRI scans and other tests to understand brain aging better.
Bern, Canton of BernAges 18–65 - NCT06222255Recruiting
Transanal irrigation for sleep issues after rectal cancer surgery
This trial tests if a special irrigation technique can improve sleep problems caused by low anterior resection syndrome (LARS) after rectal cancer surgery. It may help people who have ongoing bowel symptoms that disrupt sleep.
Seoul, Jongro-guAges 19–80 - NCT06222450Recruiting
Vestibular rehab app for dizziness after mild brain injury
This study tests a smartphone app with exercises to help improve balance and dizziness in people who have had a mild traumatic brain injury. You may be eligible if you are still experiencing dizziness or balance problems.
Tampa, FloridaAges 18 years+ - NCT06222866Recruiting
Blood thinner and inflammation monitoring after heart procedures
This study looks at how well blood thinners (anticoagulants) and inflammation markers work in people having heart or blood vessel procedures. It aims to better monitor these treatments to improve patient safety.
Innsbruck, TyrolAges 18 years+ - NCT06223529Recruiting
Music therapy for arm weakness after stroke
This study tests whether listening to music can help improve arm movement after a stroke. You will have EEG brain scans during music sessions to see how your brain responds.
Bedford, BedfordshireAges 18–110 - NCT06224426Recruiting
Oxygen Levels for Stroke Patients Having Clot Removal
This trial tests whether giving a specific level of oxygen during a procedure to remove a stroke clot improves recovery. It is for people with a moderate to severe stroke in the front part of the brain, treated within 24 hours of symptoms starting.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06224413Recruiting
Study on eli-cel for cerebral adrenoleukodystrophy
This study follows people with cerebral adrenoleukodystrophy (CALD) who have been treated with eli-cel, a gene therapy. It tracks their long-term health to see how well the treatment works in everyday care.
Boston, MassachusettsAges Any age - NCT06224959Recruiting
Migraine and nerve pain in osteoarthritis study
This study looks at whether people with osteoarthritis also have migraine headaches or nerve pain. Researchers want to better understand these connections to improve treatment.
Clermont-Ferrand, FranceAges 18 years+ - NCT06224517Recruiting
Artery health after stroke and rehabilitation
This study looks at how well your arteries are working after a stroke and how rehabilitation may help. It uses a simple, painless test (pulse wave velocity) to check artery stiffness.
TaipeiAges 18–80 - NCT06225245Recruiting
Spinal cord stimulation for arm recovery
This study tests whether a device placed on the spinal cord (called an epidural stimulator) can help improve arm and hand function in people with chronic spinal cord injuries. The goal is to boost nerve activity and make rehabilitation more effective.
Houston, TexasAges 22–65 - NCT06225752RecruitingPhase 3
Probucol for recent stroke or mini-stroke from narrowed arteries
This study tests whether the drug probucol can help people who recently had a stroke or mini-stroke caused by a narrowed artery in the brain or neck. It aims to reduce the risk of future strokes.
WuhuAges 40 years+ - NCT06226025RecruitingPhase 2
Melatonin for Bipolar Disorder in Night Owls
This trial tests whether giving melatonin at the right time can help people with bipolar disorder who are night owls improve their mood and sleep. You would take melatonin or a placebo each evening for a few weeks while tracking your symptoms on a phone app.
Ann Arbor, MichiganAges 18–60 - NCT06226077RecruitingPhase 1/Phase 2
Sleep health program for African American adults
This study is testing a culturally tailored program to help African American adults who are overweight and sleep poorly get more sleep. If you join, you'll work with a coach to improve your sleep habits and health.
Minneapolis, MinnesotaAges 21–75 - NCT06226558Recruiting
Long-Term Health of Children with Congenital CMV in NY
This study will follow children born in New York State who were tested for cytomegalovirus (CMV) as newborns. It aims to understand their long-term health and development, whether they were confirmed to have CMV, a false positive, or even a late detection if born early.
Stony Brook, New YorkAges birth–1 year - NCT06226493Recruiting
Vagus Nerve Stimulation for Stroke Recovery
This early-stage study tests if putting a mild electrical pulse on the vagus nerve (a nerve in the neck) can help the brain heal after a first-time stroke. It looks for changes in brain activity and certain DNA markers to understand how the treatment works.
Pomona, CaliforniaAges 18–80 - NCT06226259Recruiting
GABA supplement for children with insomnia
This study tests whether a natural supplement called GABA can improve sleep in children ages 6 to 12 who have insomnia. It aims to find a safe, non-medication option for better sleep.
Shanghai, Shanghai MunicipalityAges 6–12 - NCT06226805RecruitingPhase 2
Testing BB-031 for recent ischemic stroke
This study tests an experimental drug called BB-031 to see if it can safely help people who have had a recent ischemic stroke (a clot that blocks blood flow to the brain). The trial is for people who can get to the hospital within 24 hours of their first symptoms and have a moderate to severe stroke.
Scottsdale, ArizonaAges 18 years+ - NCT06227182Recruiting
Comparing MRI and ultrasound for muscle health
This study compares two imaging methods, MRI and ultrasound, to see how well they measure muscle health. It may help find better ways to monitor muscle conditions without invasive tests.
Nijmegen, GelderlandAges 18–70 - NCT06227468Recruiting
Mapping immune system genes in Greek adults
This study maps immune system genes (HLA) in Greek adults. It uses a simple cheek swab sample to collect data, with no experimental treatment.
Chaïdári, AtticaAges 18 years+ - NCT06227572Recruiting
Thinking and memory after sleep apnea treatment in Native Americans
This study looks at whether using a PAP (breathing) machine helps thinking and memory in Native American adults with sleep apnea. If you are 50 or older and just starting PAP therapy, researchers want to see how it affects your brain health.
Eagle Butte, South DakotaAges 40 years+ - NCT06227780Recruiting
Sound therapy for thinking and sensory issues in kids with developmental disorders
This trial tests whether special sound patterns played through headphones can help improve thinking and reduce sensitivity to noise in children with Fragile X syndrome or autism. The study uses a short daily listening program over several weeks to see if it makes a difference.
Cincinnati, OhioAges 5–10 - NCT06228001Recruiting
Movement monitoring in ALS patients
This study uses a wearable device to track movement patterns in people with ALS. It aims to better understand how the disease affects movement over time, which may help improve care.
LeuvenAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,435 recruiting neurology studies from the U.S. registry right now, out of 19,491 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.