Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,435 recruiting studies in this area right now.
By phase
- Not applicable9,772
- Phase 2786
- Phase 1573
- Phase 3535
- Phase 4342
- Phase 1/Phase 2304
- Phase 2/Phase 3123
Top conditions
- Stroke846
- Parkinson Disease426
- Multiple Sclerosis343
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke200
- Epilepsy196
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California680
- Massachusetts300
- New York291
- Florida274
- Texas268
- Maryland245
- Arizona214
- Alabama209
- Illinois190
- Pennsylvania177
Recruiting studies12,433 total
- NCT06280755Recruiting
AI-assisted MS care study
This study looks at how artificial intelligence (AI) can help doctors care for people with multiple sclerosis (MS) and other similar conditions. It uses existing medical data to see if AI can improve treatment decisions.
Prague, Praha 2Ages 18 years+ - NCT06281145Recruiting
Stress reduction for breast or colon cancer patients
This study tests a stress-reducing program for people with breast or colon cancer. It uses a technique called heart rate variability biofeedback to help you manage stress during treatment.
BratislavaAges 18 years+ - NCT06281223Recruiting
Brain and spinal cord connection study in spasticity
This study looks at how the brain and spinal cord connect in children with spasticity (muscle stiffness). It will help doctors understand more about this condition by studying patients who are already scheduled for surgery to reduce stiffness.
NiceAges 3–17 - NCT06281951RecruitingPhase 1
Nebulized fentanyl study in healthy volunteers
This trial tests a nebulized (inhaled mist) form of fentanyl in healthy volunteers to see how it works in the body. It is a first-in-human study of the drug given through a nebulizer, which might help people with acute pain in the future.
Rouen, FranceAges 18–68 - NCT06281756RecruitingEarly Phase 1
CBT and Trazodone for Sleep and Blood Pressure in Insomnia
This trial tests whether cognitive behavioral therapy (a type of talk therapy for sleep) and/or the medication trazodone can improve sleep and lower blood pressure in people with chronic insomnia. You must be 18 or older and have ongoing trouble sleeping.
Denver, ColoradoAges 18 years+ - NCT06282224Recruiting
Augmented reality for skull base surgery through the nose
This study tests whether using an augmented reality (AR) navigation system can help surgeons perform skull base surgery through the nose more accurately. If you are already planning this type of surgery and have had the required scans, you may be eligible.
Xiamen, FujianAges Any age - NCT06282406Recruiting
Brain stimulation guided by pupil size for hand recovery after stroke
This study tests a noninvasive (no surgery) brain stimulation technique guided by your pupil size to help improve hand function after a stroke. It is for people who had a single stroke at least 6 months ago and still have hand weakness.
Pittsburgh, PennsylvaniaAges 18–75 - NCT06282939Recruiting
Optima Coil Registry for Brain Aneurysm Treatment
This registry tracks how well the Optima Coil System works to treat brain aneurysms. It is for adults with a berry-shaped aneurysm that hasn't been treated before and is smaller than 24 mm. The goal is to see how safe and effective these coils are in real-world use.
Plano, TexasAges 18 years+ - NCT06282562Recruiting
High-intensity interval training for brain tumor patients
This study tests whether a high-intensity interval training program can help brain tumor patients feel fitter and more energetic. It's for people with stable tumors who aren't currently on treatment.
AmsterdamAges 18 years+ - NCT06282965RecruitingPhase 1/Phase 2
Angiotensin (1-7) for moderate to severe brain injury
This study tests a drug called Angiotensin (1-7) to see if it helps people recover from moderate to severe traumatic brain injury. It may reduce damage and improve healing when given shortly after the injury.
Tucson, ArizonaAges 18 years+ - NCT06283745Recruiting
Platelet-rich plasma nasal injection for smell distortion
This trial tests whether injecting a concentrated part of your own blood (platelet-rich plasma) into your nose can help improve a distorted sense of smell called parosmia. You will also do smell training at home, which is the current standard care.
Palo Alto, CaliforniaAges 18 years+ - NCT06284434RecruitingPhase 3
EXPAREL for pain after cleft gum repair
This trial tests if a long-lasting numbing medicine (EXPAREL) can help control pain after surgery to repair the gum in children and adults with cleft lip or palate. It may mean less discomfort after the procedure.
Chicago, IllinoisAges 6 years+ - NCT06284642RecruitingPhase 4
Drain and clot-dissolving medicine for severe aneurysm bleeding
This trial tests whether placing a small drain in the lower back and giving a clot-dissolving medicine (urokinase) into the fluid around the brain can help people recover from a severe bleeding stroke caused by a brain aneurysm. It is for patients who are treated quickly after the bleed.
Hefei, AnhuiAges 18 years+ - NCT06285721Recruiting
Brain stimulation for treating delirium
This trial tests if a gentle electrical brain stimulation (tACS) can help treat delirium. If you are over 50 and have had delirium for at least two days, you may be eligible.
Nijmegen, GelderlandAges 50 years+ - NCT06285539RecruitingPhase 2
Testing a drug for rare inflammatory diseases
This trial is testing a new drug (a JAK inhibitor) for people with rare inflammatory diseases like Behçet's, myositis, or IgG4-related disease that hasn't improved with standard treatments. The goal is to see if it can help control symptoms and reduce inflammation.
AmsterdamAges 18–65 - NCT06286189RecruitingPhase 1/Phase 2
Testing trazodone for sleep apnea
This trial tests whether the medication trazodone can help people with moderate to severe obstructive sleep apnea (OSA). If you have OSA and are not taking certain medications or have other sleep disorders, you may be able to join.
Boston, MassachusettsAges 21–70 - NCT06286774Recruiting
Sleep and alcohol treatment study
This study tests whether improving sleep through cognitive behavioral therapy (CBT-I) can help reduce heavy drinking in people with both alcohol use disorder and insomnia. It might be a good fit if you have trouble sleeping and drink heavily.
Columbia, MissouriAges 18–49 - NCT06286800Recruiting
Personalized brain stimulation for stroke recovery
This study tests a personalized, non-invasive brain stimulation treatment called transcranial direct current stimulation (tDCS) to help improve movement in people who have had a stroke that affects one side of the body. It aims to see if this gentle electrical stimulation can boost recovery of arm and hand function.
Houston, TexasAges 18–80 - NCT06287294Recruiting
Taste problems and dry mouth in advanced cancer
This study looks at taste problems in people with advanced cancer who also have a dry mouth. It aims to understand the link between dry mouth and taste changes to help improve symptom management.
DublinAges 18 years+ - NCT06287762Recruiting
Natural history study of RYR1-related disorders
This study follows people with RYR1-related disorders over time to learn how the condition progresses. It may help researchers plan future treatments.
Bethesda, MarylandAges 7–100 - NCT06288568Recruiting
Night shift work and obesity risk study
This study looks at how night shift work affects weight and health in hospital and factory workers. They want to see if working nights changes your body's hormones and risk for obesity.
Vienna, State of ViennaAges 21 years+ - NCT06288633Recruiting
Heart nerve ablation for slow heart rhythm
This test uses a procedure to ablate (destroy) specific nerves in the heart that may be causing your heart to beat too slowly. The goal is to help your heart speed up naturally when needed, so you may avoid needing a permanent pacemaker.
Saint PetersburgAges 18–65 - NCT06289114Recruiting
Can physical activity predict treatment success in rheumatoid arthritis?
This study tests if measuring your physical activity over a short time can help predict how well a new biologic medication will work for your rheumatoid arthritis. The goal is to find a simple way to see if the treatment is helping.
EsbjergAges 18 years+ - NCT06288763Recruiting
Nerve transfer to improve arm function in high-level tetraplegia
This study tests whether transferring a nerve from a working muscle can help restore function in the arm or hand for people with high-level tetraplegia. It may be an option if you've stopped improving with standard therapy.
Stanford, CaliforniaAges 18–80
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,435 recruiting neurology studies from the U.S. registry right now, out of 19,491 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.