Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,435 recruiting studies in this area right now.
By phase
- Not applicable9,772
- Phase 2786
- Phase 1573
- Phase 3535
- Phase 4342
- Phase 1/Phase 2304
- Phase 2/Phase 3123
Top conditions
- Stroke846
- Parkinson Disease426
- Multiple Sclerosis343
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke200
- Epilepsy196
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California680
- Massachusetts300
- New York291
- Florida274
- Texas268
- Maryland245
- Arizona214
- Alabama209
- Illinois190
- Pennsylvania177
Recruiting studies12,433 total
- NCT06273176Recruiting
Surgery with or without brain mapping for recurrent glioblastoma
This study is testing whether using a special brain-mapping technique during surgery helps people with recurrent glioblastoma. It compares standard surgery to surgery with mapping to see if it leads to better outcomes for tumors near important brain areas.
San Francisco, CaliforniaAges Up to 90 years - NCT06273475Recruiting
Robot-assisted training vs standard training for stroke recovery
This trial compares robot-assisted training to standard training to help people with stroke improve their walking and movement. It is for people who are at least 6 months past their stroke and still have moderate to severe disability.
CopenhagenAges 18 years+ - NCT06274021RecruitingEarly Phase 1
Brain stimulation to reduce leg stiffness after spinal cord injury
This study tests a non-invasive brain stimulation technique (like a gentle magnetic pulse) to see if it can reduce muscle stiffness and spasms in the legs after a spinal cord injury. It may be a good option if you have ongoing leg stiffness and want a drug-free approach.
Jackson, MississippiAges 18 years+ - NCT06274164Recruiting
RAI1 gene disorder study: biomarkers and clinical features
This study looks at people with a rare genetic condition caused by changes in the RAI1 gene. Researchers want to learn more about the condition and find markers that could help with future treatments. You and a healthy family member will spend one day in Houston for tests and samples.
Houston, TexasAges 1 month–80 years - NCT06275113Recruiting
Prevention program for heart and artery disease
This study tests a prevention program for people who have already had a heart event, stroke, or leg artery blockage. It is designed to help reduce the risk of future heart problems.
Canicattì, AGAges 18 years+ - NCT06275516Recruiting
Virtual Reality with Sights, Sounds, and Touch for Stroke Recovery
This study tests whether a special virtual reality program that uses sights, sounds, and touch can help people who have had a stroke move their leg better. You might qualify if you had a first stroke, have trouble moving your leg, and can walk a little bit with help.
Chongqing, Chongqing MunicipalityAges 18–85 - NCT06275919RecruitingPhase 2
Regorafenib for recurring meningioma
This trial tests a pill called regorafenib for people whose meningioma (a brain tumor) has come back and cannot be treated with surgery or radiation. The goal is to see if regorafenib can help stop the tumor from growing further.
Meldola, Forlì-CesenaAges 18 years+ - NCT06275815Recruiting
Parent training for early language skills
This study helps parents use simple learning activities at home to boost their child's language skills. If your child is getting speech therapy (or waiting for it) and has trouble with words, this program might be a good fit.
Columbus, OhioAges 4 years–5.9 years - NCT06276374Recruiting
Dual antiplatelet therapy after carotid artery stenting for high bleeding risk
This trial tests if taking two blood thinners (dual antiplatelet therapy) after a carotid artery stenting procedure is safe and effective for patients who have a higher risk of bleeding. It focuses on people with significant blockages in the neck arteries who are also at increased risk for serious bleeding or brain bleeds.
SeoulAges 19 years+ - NCT06276634Recruiting
Low-Oxygen Therapy for People With Multiple Sclerosis
This study tests whether brief, controlled low-oxygen episodes (called intermittent hypoxia) can improve motor function in people with MS. It may help strengthen walking and daily movement.
Chicago, IllinoisAges 18–75 - NCT06276543Recruiting
Safety study of the Bactiseal shunt catheter
This study is for people who already have a hydrocephalus shunt (a tube that drains fluid from the brain) and have had it for at least 2 years. It tests the safety of a specific catheter called Bactiseal and tracks how well it works over time.
Beijing, Beijing MunicipalityAges Any age - NCT06277154RecruitingPhase 2
MASCT-I plus chemo for first-line advanced soft tissue sarcoma
This trial tests a new immune cell therapy (MASCT-I) combined with standard chemotherapy (doxorubicin and ifosfamide) for people with advanced soft tissue sarcoma who have not had prior chemotherapy or targeted therapy. The goal is to see if the combination works better than chemo alone.
GuangzhouAges 18–70 - NCT06277063Recruiting
Nerve-stimulation device for headache in children and young adults
This trial tests if a gentle nerve-stimulating device worn on the neck (called nVNS) can prevent and treat common headaches like migraine, cluster, and tension-type headaches in children and young adults. If you often get headaches and want a drug-free option, this might help.
Guangzhou, GuangdongAges 7–20 - NCT06278259Recruiting
Exercise program for stroke recovery in seniors
This trial tests if a home-based exercise program combining aerobic and Baduanjin (a gentle Chinese exercise) can help older adults recover after a stroke. It's designed for people aged 65 or older who are medically stable.
Cairo, DokkiAges 65–75 - NCT06278428Recruiting
Epilepsy in Infants: Genes and Disease Course
This study looks at children with severe epilepsy that starts before age 2. It aims to understand how different gene changes affect the disease and how it progresses over time.
Ho Chi Minh CityAges Up to 1.9 years - NCT06278194Recruiting
Masseter muscle thickness in gasser ganglion radiofrequency treatment
This trial studies how radiofrequency treatment for facial pain affects the thickness of your chewing muscle. It may help improve future treatments.
Istanbul, BaşakşehirAges 40–85 - NCT06279247Recruiting
Body fluid markers in people with narcolepsy
This study looks at the proteins and other chemicals in body fluids (like blood or spinal fluid) of people with narcolepsy. The goal is to find markers that could help doctors better understand and diagnose narcolepsy.
Jinan, ShandongAges 5–100 - NCT06279065Recruiting
Gut bacteria and giant cell arteritis study
This trial looks at how the bacteria in your gut might affect giant cell arteritis, a condition that causes inflammation in blood vessels. It aims to help doctors better understand the disease.
Bonn, North Rhine-WestphaliaAges 18 years+ - NCT06279975Recruiting
Pupil test in patients being checked for brain death
This study uses a special camera to measure pupil reactions in patients being evaluated for brain death. The aim is to see if this test can help confirm the diagnosis of brain death more accurately.
Basel, Canton of Basel-CityAges 18 years+ - NCT06280300Recruiting
Better care planning for people with brain metastases
This study looks at whether a team-based approach to care can improve quality of life for people newly diagnosed with brain metastases from solid tumors. It aims to help coordinate your medical and support needs.
Burlington, VermontAges 18 years+ - NCT06280079Recruiting
High-calorie fatty diet for ALS patients
This trial tests a very high-calorie, fatty diet to see if it helps people with ALS. If you have been diagnosed recently and are not too advanced in the disease, this special diet may give your body extra energy to slow progression.
AachenAges 18 years+ - NCT06280482RecruitingPhase 1
Nicotinamide Riboside for Moyamoya in Smooth Muscle Dysfunction
This trial tests a vitamin B3 supplement called nicotinamide riboside (NR) to see if it can help people with Smooth Muscle Dysfunction Syndrome (SMDS) who have a specific gene mutation. The goal is to improve blood flow problems in the brain (moyamoya-like disease) caused by the condition.
Houston, TexasAges 1 year+ - NCT06280443Recruiting
Frailty and muscle loss in chronic lung disease
This study looks at people with COPD or ILD who also show signs of frailty. It aims to understand how frailty and muscle loss (sarcopenia) affect their care and use of medical resources over time.
TaichungAges 20 years+ - NCT06280742Recruiting
Brain inflammation in multiple sclerosis: a PET-MRI imaging study
This study uses a special PET-MRI scan to look at brain inflammation in people with relapsing-remitting multiple sclerosis (RRMS). It may help researchers understand how inflammation changes when starting a stronger MS treatment.
LyonAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,435 recruiting neurology studies from the U.S. registry right now, out of 19,491 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.