Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,435 recruiting studies in this area right now.
By phase
- Not applicable9,772
- Phase 2786
- Phase 1573
- Phase 3535
- Phase 4342
- Phase 1/Phase 2304
- Phase 2/Phase 3123
Top conditions
- Stroke846
- Parkinson Disease426
- Multiple Sclerosis343
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke200
- Epilepsy196
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California680
- Massachusetts300
- New York291
- Florida274
- Texas268
- Maryland245
- Arizona214
- Alabama209
- Illinois190
- Pennsylvania177
Recruiting studies12,433 total
- NCT06289348Recruiting
How is PKU announced to families after newborn screening?
This study talks to parents or doctors about how they first learned their child had PKU through newborn screening. It aims to improve how these rare metabolic diseases are communicated to families.
ParisAges 18 years+ - NCT06289413Recruiting
Nervous system changes after weight-loss surgery
This study looks at how bariatric surgery affects the part of your nervous system that controls things like heart rate and blood pressure (autonomic function). It may help patients preparing for or recovering from weight-loss surgery.
Overland Park, KansasAges 18–85 - NCT06289569Recruiting
Home therapy for recovery after stroke-related dementia
This trial tests a home-based therapy program for people who have had a stroke that led to vascular dementia. The therapy focuses on improving arm and hand movement, and it is done remotely with a caregiver's help.
Houston, TexasAges 18–110 - NCT06289582RecruitingEarly Phase 1
Brain imaging study for Parkinson's disease
This study uses a special PET scan to look at inflammation in the brain of people with Parkinson's disease or those at risk for it. The goal is to better understand the disease and possibly find new ways to track its progression.
Birmingham, AlabamaAges 18–99 - NCT06289985Recruiting
Expanding clot removal for medium vessel strokes
This trial tests a new approach to see if removing clots from medium-sized brain blood vessels can help more patients recover from stroke. It aims to expand the use of a standard clot-removal procedure to people with less severe symptoms or blockages in smaller vessels.
Birmingham, AlabamaAges 18 years+ - NCT06290713RecruitingPhase 2
Blood flow and exercise study for Duchenne muscular dystrophy
This trial tests if a medicine that improves blood flow, combined with exercise, can help muscles in boys with Duchenne muscular dystrophy. It is for boys who can still walk and are on a stable steroid medication.
Gainesville, FloridaAges 6 years+ - NCT06290661Recruiting
Nerve stimulation for shingles-related nerve pain
This study tests a treatment called peripheral nerve stimulation (using a small device to send mild electrical pulses) for people with nerve pain after shingles. It's designed for those whose pain is not well managed by usual treatments.
Wuhan, HubeiAges 18 years+ - NCT06291051Recruiting
Spinal cord stimulation for Parkinson's with painful bent spine
This study tests whether a spinal cord stimulator (a device that sends mild electrical pulses to the back) is safe and can reduce pain and improve the forward-bent posture in people with Parkinson's disease. It is for those whose bent posture has not improved with standard medication and is causing significant pain.
AmiensAges 18 years+ - NCT06291870Recruiting
Predicting long-term effects after COVID-19
This study looks at what happens to your thinking and daily health after COVID-19, especially if you have sleep apnea. It aims to find out who is more likely to have ongoing problems.
Detroit, MichiganAges 18 years+ - NCT06292117Recruiting
Genotype-guided antiplatelet therapy for stroke patients
This trial tests whether using a rapid genetic test to choose antiplatelet medication can improve outcomes for people who have had a stroke or mini-stroke. The test checks a gene that affects how your body processes a common antiplatelet drug, so your doctors can pick the safest and most effective medicine for you.
Charlottesville, VirginiaAges 18 years+ - NCT06292104Recruiting
Understanding POTS: A study on heart rate and standing
This study looks at how the body controls heart rate and blood flow in people with POTS (a condition that causes dizziness and a fast heart rate upon standing). It helps researchers understand POTS better by comparing patients with healthy volunteers.
Dallas, TexasAges 14 years+ - NCT06292377Recruiting
Understanding Fatigue After First Stroke
This study looks at why people feel very tired after a first-time stroke. It involves questionnaires, thinking and memory tests, and a brain MRI to understand sleep, mood, and fatigue better.
BrusselsAges 18 years+ - NCT06292494Recruiting
Focused ultrasound for drug-resistant epilepsy
This trial tests whether focused ultrasound can help people whose seizures are not controlled by two or more medications. You would have a noninvasive procedure while awake, pressing a stop button if needed, and your hair will be partially shaved.
TaipeiAges 18 years+ - NCT06292299Recruiting
Breathing monitor study for children with sleep or breathing issues
This study looks at how well a new breathing monitor works for children with sleep problems, breathing pauses in newborns, or epilepsy. It may help doctors better understand breathing patterns without extra needles or blood tests.
Glasgow, Glasgow CityAges 1 minute–16 years - NCT06292312Recruiting
Craniosacral therapy for multiple sclerosis
This study tests if a gentle hands-on treatment called craniosacral therapy can help people with multiple sclerosis feel better. It is for people with mild to moderate disability who are not having active relapses.
AnkaraAges 18–65 - NCT06292585Recruiting
Blocking the artery to treat epidural hematoma
This trial tests a new way to treat a blood clot outside the brain (epidural hematoma) after a head injury. Instead of surgery, doctors use a thin tube to block the artery feeding the clot, which may help the body absorb the clot more safely.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06293157Recruiting
Carbon fiber screws for spinal cancer treatment
This trial tests if carbon fiber screws are better for stabilizing the spine when cancer has spread there. It may help patients who are getting special radiation therapy (SBRT) for spinal tumors.
BydgoszczAges 18 years+ - NCT06293638Recruiting
Brain changes during deep brain stimulation for essential tremor
This study looks at how deep brain stimulation (DBS) affects brain networks in people with essential tremor (ET). The goal is to understand the brain changes that happen during DBS treatment, which may help improve the therapy.
Cleveland, OhioAges 30–80 - NCT06294158Recruiting
Light and noise in the ICU and delirium risk
This study looks at how light and noise in the intensive care unit (ICU) might affect confusion and disorientation (delirium). By tracking these environmental factors, researchers hope to find ways to reduce delirium for ICU patients.
Graz, StyriaAges 18 years+ - NCT06295263Recruiting
AI for diagnosing and treating brain diseases in older adults
This study uses artificial intelligence to help diagnose and treat brain diseases that affect older adults, such as Parkinson's and Alzheimer's. Researchers will compare AI methods with standard care to see if they can improve diagnosis and treatment.
Jinan, ShandongAges 8–100 - NCT06295146Recruiting
Getting help from a peer coach to learn wheelchair skills
This study tests whether virtual one-on-one training with a peer who has a spinal cord injury can help you learn new wheelchair skills. You'll practice using video calls, and you need a helper nearby to keep you safe during practice.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06295614Recruiting
ARC-IM therapy for walking problems in Parkinson's
This study tests a new therapy called ARC-IM to help with walking issues like freezing or balance problems in people with Parkinson's. It aims to see if the therapy is safe and can improve movement.
Lausanne, Canton of VaudAges 18 years+ - NCT06296082RecruitingPhase 2/Phase 3
Dry Needling vs Botox for Post-Stroke Leg Stiffness
This study compares two treatments for leg stiffness after a stroke: dry needling (tiny needles placed in trigger points) and Botox injections. It may help you if you've had a first stroke within the past year and have mild to moderate tightness in the calf muscles that limits ankle movement.
Antwerp, FlandersAges 18–75 - NCT06296810Recruiting
Smart brain stimulation for Parkinson's during exercise
This study tests if a smart brain stimulator (deep brain stimulation, or DBS) can adjust itself during exercise to help people with Parkinson's disease move better. The goal is to improve how well the device works while you're active.
Aurora, ColoradoAges 20–70
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,435 recruiting neurology studies from the U.S. registry right now, out of 19,491 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.