Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,432 recruiting studies in this area right now.
By phase
- Not applicable9,770
- Phase 2785
- Phase 1574
- Phase 3537
- Phase 4342
- Phase 1/Phase 2303
- Phase 2/Phase 3121
Top conditions
- Stroke846
- Parkinson Disease424
- Multiple Sclerosis343
- Alzheimer Disease340
- Dementia226
- Ischemic Stroke200
- Epilepsy196
- Obstructive Sleep Apnea155
- Insomnia153
- Spinal Cord Injuries153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke141
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis107
Leading sponsors
- Beijing Tiantan Hospital134
- Riphah International University126
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California674
- Massachusetts300
- New York291
- Florida274
- Texas267
- Maryland245
- Arizona214
- Alabama209
- Illinois190
- Pennsylvania177
Recruiting studies12,430 total
- NCT06398353Recruiting
Acupuncture for frequent primary headaches
This study tests whether acupuncture can improve quality of life for people with frequent primary headaches (like migraines or tension headaches). If you have headaches more than twice a week, this trial may help you find relief.
Taoyuan, Select A StateAges 18 years+ - NCT06399731Recruiting
Brain stimulation for mild thinking problems in Parkinson's
This trial tests if non-invasive brain stimulation can help with memory and thinking problems (mild cognitive impairment) in people with Parkinson's disease. It uses magnetic pulses and mild electrical current to stimulate the brain over a few weeks.
Amsterdam, North HollandAges Any age - NCT06399874RecruitingPhase 2
Nightmare therapy vs. wristband for veterans' nightmares
This study tests two non-drug treatments for nightmares and sleep problems in active-duty service members and veterans. You would either get a therapy that helps you change nightmare content or try a special wristband that monitors your sleep and can gently vibrate to reduce nightmares.
Bethesda, MarylandAges 22–64 - NCT06399952Recruiting
Natural history study for Baker Gordon syndrome
This study follows people with Baker Gordon syndrome over time to better understand the condition. Participants and their caregivers share medical records and complete tests and questionnaires.
Columbia, MissouriAges birth–99 years - NCT06399939Recruiting
Biphasic sleep in 9-month-old infants
This study looks at how infants sleep in two different patterns (biphasic sleep) and how that relates to their development. If your child is 9 months old and healthy, researchers will track their sleep and development over the next 6 months.
Amherst, MassachusettsAges 9 months–1.3 years - NCT06399926Recruiting
Pemetrexed via Ommaya for lung cancer in brain lining
This study tests whether a drug called pemetrexed, given directly into the fluid around your brain through a small implanted device, is safe and effective for treating lung cancer that has spread to the lining of the brain. It is for people whose cancer has a specific genetic change (EGFR, ALK, or ROS1) and who have already tried standard targeted pills that no longer control their disease.
Changsha, HunanAges 18 years+ - NCT06400017Recruiting
Deep brain stimulation study for Parkinson's disease
This trial studies how deep brain stimulation (DBS) works and can help control Parkinson's symptoms. It uses a special DBS device that is safe for MRI scans.
Beijing, Beijing MunicipalityAges 50–70 - NCT06400849Recruiting
Cooling and compression to prevent nerve damage from chemo
This trial tests whether adding a cooling and compression treatment to your hands and feet during chemotherapy can help prevent nerve damage (neuropathy) caused by the drug paclitaxel. It may be a good option for people with breast cancer who are about to start this type of chemotherapy and want to reduce side effects.
NiceAges 18–99 - NCT06400901Recruiting
Brain signals during recovery from anesthesia for DBS patients
This trial records brain activity during recovery from general anesthesia in people undergoing deep brain stimulation (DBS) surgery. It aims to understand how the brain wakes up after anesthesia.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06400940RecruitingPhase 4
Testing a flow-diverting stent for brain aneurysms that returned
This trial tests a special stent (DERIVO) for brain aneurysms that have come back after earlier treatment. It's for people who cannot have other treatments like coiling or surgery.
Saint PetersburgAges 18 years+ - NCT06400992Recruiting
Testing Sky hearing technology in children
This study is testing the Sky CI sound processor in children aged 6–16 who use cochlear implants and/or hearing aids. The goal is to see how well the Sky technology works for hearing in noise.
ParisAges 6–16 - NCT06401564Recruiting
Virtual reality rehab after ischemic stroke
This study tests whether using virtual reality (VR) exercises in the hospital can help people recover arm movement and function after an ischemic stroke. You may be a candidate if you have weakness in one arm and can follow directions.
Stony Brook, New YorkAges 18 years+ - NCT06401642RecruitingPhase 4
Zavegepant for acute migraine with CGRP preventives
This study tests how well a new acute migraine medicine, zavegepant, works and is tolerated in people who are already taking a CGRP-targeting preventive medication. It may help you find an effective treatment when you get a migraine attack.
Phoenix, ArizonaAges 18 years+ - NCT06401772Recruiting
Body posture to prevent repeat brain bleed after surgery
This trial tests whether lying in a specific body position after surgery can help prevent a chronic subdural hematoma from coming back. It is for people aged 60 and older who have had a small drainage procedure for this type of brain bleed.
Shanghai, Shanghai MunicipalityAges 60 years+ - NCT06401824RecruitingPhase 2
Combination drug therapy for lung cancer with brain spread
This trial tests a combination of two drugs, sacituzumab govitecan and bevacizumab, for people with a specific type of lung cancer (non-squamous) that has spread to the brain. It aims to see if this treatment can shrink brain tumors and improve outcomes.
AmsterdamAges 18 years+ - NCT06401993Recruiting
Brain connection study of tinnitus treatment with Chinese medicine
This study tests a traditional Chinese medicine treatment called 'Dao qi Tong Luo' for chronic tinnitus. It uses a safe brain scan (fNIRS) to see how the treatment affects brain connections related to hearing.
HangzhouAges 20–55 - NCT06402955RecruitingPhase 2
Imaging depression in Parkinson's disease
This study uses brain imaging (PET scans) to understand depression in people with Parkinson's disease. It may also test a depression treatment called ketamine, but the main goal is to see how the brain changes with depression.
New Haven, ConnecticutAges 40–80 - NCT06402942Recruiting
Game-based occupational therapy for teens with Duchenne
This trial tests a fun, game-based occupational therapy program for teens with Duchenne muscular dystrophy. It aims to help you build skills and stay engaged through activities you can do at home on a computer or tablet.
AnkaraAges 13–18 - NCT06403267RecruitingPhase 2
Testing NoNO-42 for moderate to severe ischemic stroke
This study tests a new drug called NoNO-42 for people having a moderate to severe ischemic stroke. You can join if you get clot-busting medicine within 4.5 hours of your stroke and may also have a procedure to remove the clot.
Calgary, AlbertaAges 18–90 - NCT06403475Recruiting
Vagus nerve stimulation for aphasia after stroke
This study tests whether a gentle electrical stimulation on the skin of the ear (called tVNS) can help improve word finding in people with aphasia after a stroke. You will use a computer speech program while receiving the stimulation or a placebo.
SheffieldAges 18 years+ - NCT06405334Recruiting
Study on balance problems in Parkinson's disease
This study looks at how Parkinson's disease affects balance and the brain signals involved. It aims to understand why some people with Parkinson's have trouble with balance, and in part of the study, it will look at how deep brain stimulation (a device that sends electrical impulses to the brain) affects balance.
Minneapolis, MinnesotaAges 18 years+ - NCT06405438Recruiting
Mud therapy vs. paraffin wax for carpal tunnel syndrome
This trial compares two non-surgical treatments—mud therapy (peloid) and paraffin wax—for people with mild to moderate carpal tunnel syndrome. It aims to see which one better eases symptoms like numbness, tingling, and hand pain.
IstanbulAges 18–65 - NCT06405594Recruiting
Studying sentence production in aphasia
This study looks at how people with aphasia (language trouble after a stroke) produce sentences, compared to healthy adults. By understanding these brain processes, researchers hope to improve language recovery strategies.
College Park, MarylandAges 18 years+ - NCT06405750Recruiting
Study of the left atrial appendage during open-heart surgery
This study looks at a part of the heart called the left atrial appendage during open-heart surgery. It aims to learn more about heart rhythm problems and blood clots, which may help improve future treatments.
CopenhagenAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,432 recruiting neurology studies from the U.S. registry right now, out of 19,532 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.