Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,432 recruiting studies in this area right now.
By phase
- Not applicable9,770
- Phase 2785
- Phase 1574
- Phase 3537
- Phase 4342
- Phase 1/Phase 2303
- Phase 2/Phase 3121
Top conditions
- Stroke846
- Parkinson Disease424
- Multiple Sclerosis343
- Alzheimer Disease340
- Dementia226
- Ischemic Stroke200
- Epilepsy196
- Obstructive Sleep Apnea155
- Insomnia153
- Spinal Cord Injuries153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke141
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis107
Leading sponsors
- Beijing Tiantan Hospital134
- Riphah International University126
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California674
- Massachusetts300
- New York291
- Florida274
- Texas267
- Maryland245
- Arizona214
- Alabama209
- Illinois190
- Pennsylvania177
Recruiting studies12,430 total
- NCT06390761Recruiting
Acupuncture for constipation in Parkinson's disease
This trial tests whether acupuncture can help relieve constipation in people with Parkinson's disease. If you have both Parkinson's and constipation that is not caused by another medical condition, this study may offer a non-drug treatment option.
Xi'an, ShaanxiAges 35–80 - NCT06391086Recruiting
Focused ultrasound for arm recovery after recent stroke
This study tests if focused ultrasound (a noninvasive sound wave therapy) can help improve arm and hand movement after a recent stroke. It is for people whose stroke occurred within the last three months and who still have some arm weakness.
TaipeiAges 18 years+ - NCT06391736RecruitingPhase 1/Phase 2
Gene therapy for late-onset Pompe disease
This trial tests a new gene therapy for late-onset Pompe disease. The therapy aims to help your body produce the enzyme needed to break down glycogen, which may improve muscle and breathing function.
BeijingAges 6 years+ - NCT06392386RecruitingPhase 2/Phase 3
Efgartigimod for children with generalized myasthenia gravis
This study tests an investigational drug called efgartigimod for children and teens with generalized myasthenia gravis. It may help those who haven't responded well enough to standard treatments.
Charlotte, North CarolinaAges 2–17 - NCT06393439Recruiting
Virtual reality for functional movement disorder
This study tests whether virtual reality can help people with functional or essential tremor. You may join if you have one of these tremor types or are a healthy volunteer.
GrazAges 18–65 - NCT06392815Recruiting
PET scan for Lyme neuroborreliosis diagnosis
This trial tests whether a special PET scan (64Cu-DOTATATE) can help diagnose Lyme neuroborreliosis (LNB), an infection of the nervous system caused by Lyme disease. The study aims to see if this scan can detect the infection earlier or more accurately than current methods.
Copenhagen, Capital RegionAges 18–90 - NCT06392945Recruiting
Walking and thinking training with music for chronic stroke recovery
This trial tests whether adding a rhythmic beat (like a metronome or music) to walking while doing thinking tasks can improve walking after a stroke. It is for people who had a stroke more than 6 months ago and can already walk a short distance.
TaipeiAges 20–85 - NCT06393101RecruitingPhase 1
High-CBD cannabis extract for complex regional pain syndrome treatment
This study tests a high-CBD cannabis extract (BRC-002) to see if it can help reduce pain and improve health in people with Complex Regional Pain Syndrome (CRPS). Participants will not use opioids or other cannabis during the study.
La Jolla, CaliforniaAges 21–75 - NCT06394180Recruiting
Study of perforations during clot removal for stroke
This trial looks at what happens when a hole (perforation) occurs in a brain artery during clot removal for stroke. It compares patients who had this complication to those who did not, to understand how to better manage it.
BaselAges 18 years+ - NCT06394232RecruitingPhase 1/Phase 2
Testing a cell therapy for advanced dry AMD with geographic atrophy
This trial tests a new treatment called Eyecyte-RPE™, made from special cells that support the retina. It is given as a single injection under the retina during eye surgery. The study aims to see if it can help people with advanced dry age-related macular degeneration (AMD) who have large areas of damage (geographic atrophy) in the center of their vision.
Jālna, MaharashtraAges 50–100 - NCT06394453Recruiting
Feeding during cooling for brain injury in newborns
This study looks at whether it is safe to give small amounts of milk to babies who are being cooled for brain injury after a difficult birth. It may help doctors decide if feeding during cooling can improve outcomes.
CracowAges Up to 6 hours - NCT06394310Recruiting
Dry needling for leg tightness in MS
This study tests whether dry needling (a therapy using thin needles to release muscle tightness) can help reduce leg stiffness and improve walking in people with multiple sclerosis. If you have leg spasticity and can walk with some help, this trial may be a good fit.
Kansas City, KansasAges 18–64 - NCT06395272Recruiting
Can a device improve walking after a stroke?
This trial tests a device called SURA that stimulates feeling in the ankle after a stroke. It may help people who have foot drop or trouble lifting their foot while walking.
Barcelona, Vilafranca Del PenedésAges 18–85 - NCT06395506Recruiting
Exercise and creatine for breast cancer survivors
This trial tests if adding creatine supplements to a virtual exercise program helps breast cancer survivors recover after chemotherapy. Participants will attend online exercise sessions three times a week and take creatine by mouth.
Galveston, TexasAges 18–75 - NCT06396260Recruiting
Brain network study in ALS with emotional outbursts
This study looks at how ALS affects the brain's structure and networks, especially in people who have sudden emotional outbursts (pseudobulbar affect). You will have brain scans (MRI and MEG) and answer questions to help researchers understand these changes.
Aalborg, Northern JutlandAges 18–90 - NCT06396325Recruiting
Active video game trial for arm strength in kids with SMA
This trial tests whether playing active video games (exergaming) with your arms can help children and teens with spinal muscular atrophy improve their arm strength and function. If you join, you'll play specially designed games for a period of time, and researchers will see if it makes a difference.
Calgary, AlbertaAges 8–18 - NCT06396299Recruiting
Atrial fibrillation blood thinner outcomes study
This study follows people with atrial fibrillation to see how well blood-thinning medications work and what outcomes they experience over time. It aims to improve treatment guidance for patients with this common heart rhythm condition.
Bangkok, BangkokAges 18–100 - NCT06396520Recruiting
Brain MRI study for babies at risk of cerebral palsy
This study uses safe MRI scans during natural sleep to look at how babies' brains develop, especially those at risk for cerebral palsy. It aims to find early signs of movement problems so treatment can start sooner.
Hvidovre, Capital RegionAges 2 months–11 months - NCT06397196Recruiting
Laser-guided neck exercises for cervical radiculopathy
This study tests if combining laser guidance with neck exercises helps people with cervical radiculopathy (nerve pain in the neck that travels to the arm) improve their neck control and reduce pain. It may be a good fit if you have moderate neck-related arm pain.
Sialkot, Punjab ProvinceAges 35–55 - NCT06397339Recruiting
Training clinics to improve Alzheimer's care for American Indian elders
This trial tests a training program for primary care clinics serving American Indian and Alaska Native communities. The goal is to improve care for patients with memory loss or dementia.
Seattle, WashingtonAges 18 years+ - NCT06397365Recruiting
Hypnosis for better CPAP use
This trial tests if hypnosis sessions can help people with sleep-disordered breathing use their CPAP machine more consistently, especially if they are currently using it less than 3 hours a night.
Lausanne, Canton of VaudAges 18 years+ - NCT06397469Recruiting
Digital program for attention and wellbeing in older adults
This study tests a digital program designed to help improve attention and overall wellbeing in older adults. You can take part from home using your own smartphone or tablet.
San Francisco, CaliforniaAges 60–99 - NCT06397937Recruiting
Helping stroke survivors with social needs after leaving the hospital
This study tests a program that helps stroke survivors with social needs (like housing or finances) when they go home. It's for Black or Hispanic adults in NYC who had a recent stroke and want extra support after discharge.
New York, New YorkAges 18–75 - NCT06398158Recruiting
Ravulizumab and its impact on neuromyelitis optica
This study looks at how well ravulizumab (Ultomiris) works for people with neuromyelitis optica spectrum disorder (NMOSD) by tracking symptoms and MRI scans over time. It aims to see if the drug helps control the disease in real-world use.
Dallas, TexasAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,432 recruiting neurology studies from the U.S. registry right now, out of 19,532 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.