Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,432 recruiting studies in this area right now.
By phase
- Not applicable9,770
- Phase 2785
- Phase 1574
- Phase 3537
- Phase 4342
- Phase 1/Phase 2303
- Phase 2/Phase 3121
Top conditions
- Stroke846
- Parkinson Disease424
- Multiple Sclerosis343
- Alzheimer Disease340
- Dementia226
- Ischemic Stroke200
- Epilepsy196
- Obstructive Sleep Apnea155
- Insomnia153
- Spinal Cord Injuries153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke141
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis107
Leading sponsors
- Beijing Tiantan Hospital134
- Riphah International University126
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California674
- Massachusetts300
- New York291
- Florida274
- Texas267
- Maryland245
- Arizona214
- Alabama209
- Illinois190
- Pennsylvania177
Recruiting studies12,430 total
- NCT06406569Recruiting
Home arm rehab technology for stroke recovery
This study tests new technologies to help people recover arm movement after a stroke. You would use special devices at home with a caregiver's help, and the team will see how well they work for you.
Singapore, SingaporeAges 21–80 - NCT06406413Recruiting
Micro-movements in prolonged disorders of consciousness
This trial studies tiny, subconscious movements in people who have been in a coma or minimal consciousness for over a month after a severe brain injury. It aims to understand these movements better, which could help improve care and communication.
Hanzhou, ZhejiangAges 18–80 - NCT06406647Recruiting
Nerve block for arm surgery
This trial tests a nerve block to help with pain during and after upper arm surgery. The goal is to see if it works well and is safe for patients.
AsyutAges 20–65 - NCT06406712Recruiting
Nerve block for arm vascular surgery
This trial tests a nerve block to numb the arm during vascular surgery. It may help manage pain and reduce the need for general anesthesia.
AsyutAges 20–65 - NCT06406790RecruitingPhase 4
Studying a new sealant for brain surgery
This trial tests a product called CraniSeal, which is used to help seal the covering of the brain (the dura) after surgery. It may lower the risk of fluid leaks after certain types of planned brain surgeries.
Los Angeles, CaliforniaAges 18 years+ - NCT06406725Recruiting
Detecting vocal cord issues with noninvasive breathing test
This study tests whether a noninvasive breathing support device can detect vocal cord movement problems in children who had heart or airway surgery. It may avoid the need for a scope test.
Queens, New YorkAges 1 day–18 years - NCT06406855Recruiting
Brain-controlled spinal stimulation walking therapy for spinal cord injury
This trial tests a therapy that uses a brain-controlled device to stimulate your spinal cord while you practice walking. It aims to help people with incomplete spinal cord injury improve their walking ability.
Miami, FloridaAges 18–70 - NCT06407219Recruiting
Robot-assisted walking training for nerve or muscle problems
This study tests if a single session of walking with a robotic device called Trexo can help people who have trouble walking due to a nerve or muscle condition. The robot supports your legs and helps you practice walking.
Calgary, AlbertaAges 4 years+ - NCT06407830Recruiting
Walking therapy with and without muscle stimulation for stroke recovery
This study tests whether adding electrical muscle stimulation to a walking and movement program helps stroke survivors walk better, become more independent, and improve their quality of life.
Lahore, Punjab ProvinceAges 45–65 - NCT06407518Recruiting
Preoperative medicine for pain relief in colorectal cancer patients with sleep or anxiety issues
This trial tests whether taking a medicine called midazolam before surgery can help with pain after surgery in people with colorectal cancer who have trouble sleeping or feel anxious. You would receive the medicine as a drink before your operation.
Guangzhou, GuangdongAges 18–60 - NCT06408259RecruitingPhase 3
Comparing ozanimod and fingolimod for children with MS
This study compares two oral medications, ozanimod and fingolimod, to see which one works better and is safer for children and teenagers with relapsing-remitting MS. Both drugs help reduce MS attacks and slow down the disease.
Loma Linda, CaliforniaAges 10–17 - NCT06408246RecruitingPhase 2
Cognitive training and medication for depression
This study tests whether a combination of cognitive training (brain exercises) and a medication (guanfacine or sertraline) can improve thinking skills in people with depression. It involves MRI scans and computer tasks to understand how your brain responds.
Palo Alto, CaliforniaAges 18–60 - NCT06408662Recruiting
Remote mindfulness program for tics (Tourette or tic disorder)
This study tests a mindfulness program delivered remotely (via phone or tablet) to help people with moderate to severe tics. It aims to see if mindfulness can reduce tic severity and improve quality of life.
Baltimore, MarylandAges 18 years+ - NCT06409338Recruiting
Ear nerve stimulation for Parkinson's motor symptoms
This study tests whether a gentle nerve stimulation on the ear (taVNS) can improve movement symptoms in Parkinson's disease. It aims to understand how this stimulation affects the brain.
Nanjing, JiangsuAges 40–80 - NCT06409351Recruiting
Physical activity program for stroke survivors
This trial tests a program to help people who have had a stroke get more physically active. If you are at least 6 months past your stroke, live at home, and can walk, you may be able to join a supported self-management program to build healthy habits.
Singapore, SingaporeAges 21–90 - NCT06409364RecruitingPhase 2
Fludrocortisone for brain aneurysm bleeding recovery
This trial tests a medicine called fludrocortisone to see if it helps people recover after a subarachnoid hemorrhage (a type of brain bleed from an aneurysm). The study is for adults who are already being cared for in an intensive care unit shortly after their aneurysm is treated.
New Lambton Heights, New South WalesAges 18 years+ - NCT06409806Recruiting
Brain retraction monitoring during surgery
This trial monitors brain activity during surgery to see how using a retractor to hold brain tissue still might affect the brain. It may help surgeons understand how to protect the brain during these procedures.
London, Greater LondonAges 16 years+ - NCT06409754Recruiting
Brain-computer interface for arm recovery after stroke
This trial tests a brain-computer interface system that helps move your arm using electrical stimulation. It is for people who have had a stroke at least 6 months ago and have lasting weakness in one arm.
Mexico City, Mexico CityAges 18 years+ - NCT06409832Recruiting
Study of rimegepant for migraine prevention
This study tests a medicine called rimegepant to see if it helps prevent migraines. If you have migraine at least 4 days per month, this might be for you.
Florence, FlorenceAges 18 years+ - NCT06410001RecruitingPhase 1/Phase 2
Cervical stimulation study for spinal cord injury recovery
This study tests whether a device placed near the spinal cord in your neck (called an epidural stimulator) can help improve arm and hand function after a spinal cord injury. It's designed for people with a long-term, motor-complete injury between the C4 and C7 levels.
Minneapolis, MinnesotaAges 22 years+ - NCT06410157Recruiting
Mindfulness for heart-brain health in adults 50-70
This study tests whether a daily mindfulness practice can help older adults improve how their heart and brain work together. You will do breathing exercises at home and come to USC twice for check-ups, including blood and urine tests and an MRI.
Los Angeles, CaliforniaAges 50–70 - NCT06410261Recruiting
Exercise program for MS patients who use wheelchairs
This study tests an exercise program designed for people with MS who use a wheelchair but can still walk short distances with help. The goal is to see if this program improves fitness and quality of life.
Chicago, IllinoisAges 18 years+ - NCT06410274Recruiting
MRI study of brain damage after bleeding stroke
This study looks at small areas of damage (called ischaemic lesions) seen on MRI after a bleeding stroke. It aims to understand how common they are and what they mean for recovery. Participants will have an MRI scan within a few days of their stroke.
LeicesterAges 18–120 - NCT06410495Recruiting
Digital family sleep program for children with ODD
This study tests a digital program for families to help children with Oppositional Defiant Disorder (ODD) and their parents get better sleep. The program provides tools and support to improve sleep habits for both the child and the parent.
Tampa, FloridaAges 8–17
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,432 recruiting neurology studies from the U.S. registry right now, out of 19,532 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.