Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,432 recruiting studies in this area right now.
By phase
- Not applicable9,770
- Phase 2785
- Phase 1574
- Phase 3537
- Phase 4342
- Phase 1/Phase 2303
- Phase 2/Phase 3121
Top conditions
- Stroke846
- Parkinson Disease424
- Multiple Sclerosis343
- Alzheimer Disease340
- Dementia226
- Ischemic Stroke200
- Epilepsy196
- Obstructive Sleep Apnea155
- Insomnia153
- Spinal Cord Injuries153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke141
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis107
Leading sponsors
- Beijing Tiantan Hospital134
- Riphah International University126
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California674
- Massachusetts300
- New York291
- Florida274
- Texas267
- Maryland245
- Arizona214
- Alabama209
- Illinois190
- Pennsylvania177
Recruiting studies12,430 total
- NCT06476093Recruiting
Radiation plus anlotinib for lung cancer brain spread
This trial tests a combination of focused radiation (stereotactic radiosurgery) and an oral targeted therapy called anlotinib for people with non-small cell lung cancer that has spread to the brain. It may offer a way to control brain metastases without more invasive procedures.
Lianyungang, JiangsuAges 18–80 - NCT06476782Recruiting
Motor learning and exercise for stroke recovery
This study tests a combined motor relearning program and aerobic exercise to improve balance and leg function in people recovering from a stroke that happened 1 to 5 months ago. If you qualify, you would receive this therapy to help with your standing stability and walking ability.
Sialkot, Punjab ProvinceAges 50–70 - NCT06476912Recruiting
Balance exercise and nerve stimulation for Parkinson's with anxiety
This study tests whether combining balance exercises with a gentle nerve stimulation (called vagus nerve stimulation) can help people with Parkinson's disease who also have anxiety. The goal is to see if this combination improves walking and balance.
TaipeiAges 40–85 - NCT06477484Recruiting
Blood tests to help screen for Alzheimer's
This study is testing whether blood-based markers can help identify Alzheimer's disease earlier. It is for people with Alzheimer's, mild memory problems, or no memory issues at all.
Beijing, Beijing MunicipalityAges 50 years+ - NCT06477796Recruiting
Improving sleep in veterans with TBI and sleep problems
This study tests a new way to help Veterans with both a traumatic brain injury (TBI) and sleep problems get better rest. If you are a Veteran with sleep trouble and a history of TBI, this program may help improve your sleep without needing extra medication.
Portland, OregonAges 18–89 - NCT06477809Recruiting
Testing a device to help blind people with daily tasks
This trial tests a new device (ARIA) that helps people who are blind navigate daily tasks. If you have no light perception or only light perception, use a long cane, and are comfortable with a smartphone, you may be able to take part in 4 sessions in Sydney.
Sydney, New South WalesAges 18 years+ - NCT06478238RecruitingEarly Phase 1
Calcium folinate for hereditary spastic paraplegia type 56
This trial tests a drug called calcium folinate (a form of vitamin B9) to see if it can help people with a rare genetic type of spastic paraplegia (SPG56). It aims to improve leg stiffness and weakness caused by a specific gene change.
Shanghai, Shanghai MunicipalityAges Any age - NCT06478784Recruiting
Strength training for multiple sclerosis: a randomized trial
This study tests whether a strength-training program (like lifting weights or using resistance bands) can help people with multiple sclerosis feel better and move better. It is for people who can walk on their own and have been stable (no recent relapses).
ValladolidAges 18 years+ - NCT06479083Recruiting
Parkinson's telemedicine support and treatment study
This study uses telemedicine to help coordinate care for people with Parkinson's disease or related conditions. It aims to improve treatment and support across different doctors and services.
HomburgAges 30–85 - NCT06479343Recruiting
Liquid embolic for brain vessel malformations
This trial tests a new liquid material (called a liquid embolic system) that is injected into the abnormal blood vessels in the brain to block them off. It is for people who have a cerebrovascular malformation and can be treated with a catheter from inside the blood vessel.
Guangzhou, GuangdongAges 18–80 - NCT06479577Recruiting
Comparing ultrasound and laser therapy for diabetic foot pain
This study compares two physical therapy methods (ultrasound and high-intensity laser therapy) to see which one better reduces nerve pain, improves strength, and boosts quality of life in people with diabetic foot pain.
Bahawalpur, Punjab ProvinceAges 50–75 - NCT06479811RecruitingPhase 1
Radioactive drug for advanced neuroendocrine and other cancers
This trial tests a new radioactive drug, [212Pb]VMT-Alpha-NET, that targets a protein on certain cancer cells. It is for people with specific types of advanced cancers that have gotten worse and are not responding to standard treatments.
Bethesda, MarylandAges 18–120 - NCT06479863RecruitingEarly Phase 1
Testing a new drug combo for inclusion body myositis
This trial tests a combination of two investigational drugs (pozelimab and cemdisiran) to see if they can help people with sporadic inclusion body myositis, a muscle disease that causes progressive weakness. If the drugs work, they may slow down the disease and help you stay stronger longer.
Austin, TexasAges 45–75 - NCT06480162Recruiting
How breathing machines affect the brain's memory center
This trial studies how mechanical ventilation (breathing machine) affects the hippocampus, a part of the brain important for memory. It may help people who already have an electrode in their hippocampus understand how breathing support impacts brain function.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06480188Recruiting
Comparing two brain stimulation targets for craniocervical dystonia
This trial tests how deep brain stimulation (DBS) works when targeting two different brain areas (STN or GPi) for people with craniocervical dystonia. It aims to find which target better helps symptoms and why.
Hefei, AnhuiAges 18–75 - NCT06480266Recruiting
Can more protein protect muscles during radiation?
This study tests whether a higher protein diet can help keep your muscles strong and improve your quality of life during and after radiation therapy. If you are getting radiation for cancer, you might be asked to follow a specific nutrition plan.
Berlin, State of BerlinAges 45–75 - NCT06480786Recruiting
Spinal cord stimulator for diabetic nerve and artery pain
This study tests if a spinal cord stimulator (a device that sends mild electrical pulses to the spine) can relieve severe leg pain caused by diabetic nerve damage and poor blood flow. It may help people who have not found enough relief from other treatments.
Omaha, NebraskaAges 19–89 - NCT06481176Recruiting
How exercise affects blood in restless legs syndrome
This trial studies how a single session of exercise changes blood markers in people with restless legs syndrome (RLS) who are not currently being treated. If you have moderate to severe RLS and are not regularly active, this study may help us understand how exercise affects your condition.
Stanford, CaliforniaAges 18 years+ - NCT06481540Recruiting
Smartphone app for cough training in Parkinson's
This trial tests a smartphone app called SpiroGym to help people with Parkinson's disease improve their cough strength. It aims to see if app-guided exercises can make coughing more effective for clearing the airway.
PragueAges 40–80 - NCT06481878Recruiting
Testing a stool test for Alzheimer’s markers
This study checks if Alzheimer’s-related proteins (amyloid and tau) can be found in stool samples. It may help develop a simple, non-invasive way to detect Alzheimer’s disease.
GrenobleAges 40 years+ - NCT06482138Recruiting
Why smell may change after COVID-19: a nose tissue study
This study looks at why some people lose or change their sense of smell after COVID-19. Researchers will take a tiny sample of tissue from your nose to study the cells and molecules involved.
Brussels, Brussels CapitalAges 18–70 - NCT06482463Recruiting
D-lactate test for meningitis in patients with a brain drain
This study checks if a substance called D-lactate in the fluid around your brain can help diagnose meningitis that develops in the hospital after a brain drain (ventriculostomy). It aims to improve diagnosis.
ToulouseAges 18 years+ - NCT06482502Recruiting
Testing arm function in Parkinson's with a ring and board test
This study checks if a 6-minute pegboard and ring test is a valid way to measure arm function in people with Parkinson's. It may help find better ways to track arm movement issues.
IstanbulAges 45–75 - NCT06482554RecruitingPhase 3
Lumateperone for Apathy in Psychotic Disorders
This trial tests a medication called lumateperone to see if it can improve apathy (lack of motivation) in people who have psychotic symptoms from schizophrenia or related disorders. It may help if you are already on a stable treatment but still struggle with apathy.
Shreveport, LouisianaAges 18–65
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,432 recruiting neurology studies from the U.S. registry right now, out of 19,532 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.