Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,432 recruiting studies in this area right now.
By phase
- Not applicable9,770
- Phase 2785
- Phase 1574
- Phase 3537
- Phase 4342
- Phase 1/Phase 2303
- Phase 2/Phase 3121
Top conditions
- Stroke846
- Parkinson Disease424
- Multiple Sclerosis343
- Alzheimer Disease340
- Dementia226
- Ischemic Stroke200
- Epilepsy196
- Obstructive Sleep Apnea155
- Insomnia153
- Spinal Cord Injuries153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke141
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis107
Leading sponsors
- Beijing Tiantan Hospital134
- Riphah International University126
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California674
- Massachusetts300
- New York291
- Florida274
- Texas267
- Maryland245
- Arizona214
- Alabama209
- Illinois190
- Pennsylvania177
Recruiting studies12,430 total
- NCT06471634Recruiting
Improving sleep and reducing sitting time in type 2 diabetes
This study tests whether a program to improve sleep and reduce sitting time can help people with type 2 diabetes. It combines cognitive behavioral therapy for insomnia with tips to move more during the day.
Leicester, LeicestershireAges 18–75 - NCT06471751Recruiting
Muscle training for moderate sleep apnea
This trial tests whether a 3-month program of muscle exercises for breathing and mouth strengthens the airway, to help people with moderate sleep apnea breathe better during sleep and possibly reduce their symptoms.
GrenobleAges 18 years+ - NCT06472102Recruiting
Heart nerve ablation for severe fainting
This study tests a procedure called cardioneuroablation, which uses targeted heat (radiofrequency) to calm overactive nerves that cause your heart to beat too slowly and make you faint. The goal is to stop severe fainting spells in people with reflex syncope who haven't gotten better with other treatments.
Warsaw, Masovian VoivodeshipAges 14 years+ - NCT06472323Recruiting
Pulsed radiofrequency with platelet-rich plasma for trigeminal neuralgia
This trial tests a treatment that combines pulsed radiofrequency and platelet-rich plasma to see if it works better for trigeminal neuralgia pain that hasn't been helped by standard medicines like carbamazepine.
Beijing, Beijing MunicipalityAges 18–75 - NCT06472336Recruiting
Stenting for severe stroke caused by plaque buildup
This trial tests whether placing a stent (a tiny tube) in the blocked artery in the brain can improve blood flow and help people recover from a severe stroke, especially when standard clot removal has not worked.
Basel, Canton of Basel-CityAges 18 years+ - NCT06472375Recruiting
24-hour observation after fainting in the hospital
This study looks at whether people who come to the hospital after a fainting spell can be safely watched for 24 hours inside the hospital, instead of being admitted for a longer stay. It may help doctors decide the best way to monitor low- and intermediate-risk fainting.
AmsterdamAges 18 years+ - NCT06472505Recruiting
Using a special mesh to prevent fluid leaks after pituitary surgery
This trial tests if using a polyglycolic acid mesh during endoscopic nasal surgery for pituitary tumors can help prevent cerebrospinal fluid leakage. This may reduce the risk of complications after surgery.
TaipeiAges 20 years+ - NCT06472557Recruiting
Study of spinocerebellar ataxia type 27B over time
This study follows people with spinocerebellar ataxia type 27B (a movement disorder) and their family members to understand how the condition changes over time. It also includes healthy volunteers for comparison.
PragueAges 18–99 - NCT06472622RecruitingEarly Phase 1
Brain imaging study of pain and effort
This study uses brain scans to understand how people experience pain and effort. It compares healthy volunteers to people with ME/CFS to see if there are differences in brain activity.
Bethesda, MarylandAges 18–50 - NCT06472674Recruiting
Healthy Aging Study for Older Adults
This study is looking at healthy aging in older adults who live in the community. It involves completing a survey to help researchers understand how people age well.
BeijingAges 60 years+ - NCT06472986Recruiting
Activity-based therapy with spinal stimulation for spinal cord injury
This study tests whether combining activity-based therapy (exercises to improve arm and hand function) with a mild electrical stimulation on the skin of your back can help people with chronic neck-level spinal cord injury regain more arm and hand movement.
Toronto, OntarioAges 18 years+ - NCT06473415Recruiting
Lormetazepam for sleep in the ICU
This trial tests whether a sleep medication called lormetazepam can improve sleep quality and brain activity in ICU patients who are on a breathing machine. It may help if you need sedation and are expected to stay in the ICU for at least two days.
Mitte, State of BerlinAges 18–100 - NCT06473272Recruiting
Ultrasound to study neck artery plaques and predict risk
This study uses different ultrasound techniques to look at plaques in the neck artery and predict future heart or stroke events. It may help doctors understand which plaques are more dangerous.
Shanghai, Shanghai MunicipalityAges 40–100 - NCT06473389Recruiting
A treatment for shoulder pain after stroke
This trial tests a treatment called suprascapular radiofrequency ablation (a targeted heat procedure) to help relieve shoulder pain after a stroke. It is for people who have had a stroke at least 3 months ago and still have severe shoulder pain.
Ankara, YenimahalleAges 18 years+ - NCT06473714Recruiting
Brain stimulation for language in progressive aphasia
This trial tests a gentle, non-invasive brain stimulation called tDCS to see if it can help improve language control in people with primary progressive aphasia. It is done in a hospital in Nice, France.
NiceAges 18 years+ - NCT06473597RecruitingPhase 4
Comparing Nurtec and Maxalt for migraine in the ER
This trial tests two fast-dissolving migraine medicines, Nurtec ODT and Maxalt MLT-ODT, in adults coming to the emergency room with a migraine. The goal is to see which one works better and faster for pain relief.
Brooklyn, New YorkAges 18–65 - NCT06473987Recruiting
Virtual reality training for better walking after brain injury
This trial tests a virtual reality program that combines thinking and walking exercises to help improve your balance and walking speed. It may be a good fit if you have a traumatic brain injury and walk more slowly than usual.
West Orange, New JerseyAges 18–65 - NCT06474533Recruiting
FET PET for evaluating brain tumors
This study tests a special imaging agent called fluoroethyltyrosine (FET) to see if it can better detect brain tumors on PET scans. It may help doctors decide if a tumor has come back after treatment or better guide initial biopsy or surgery.
San Francisco, CaliforniaAges 4 years+ - NCT06474507Recruiting
Calculus Bovis Sativus for Stroke Recovery
This study tests an investigational traditional Chinese medicine called Calculus Bovis Sativus (CBS) for people who have had an ischemic stroke or have small vessel disease in the brain. It aims to see if CBS can help recovery and is safe to use.
Wuhan, HubeiAges 18 years+ - NCT06474520Recruiting
Bovine gallstone extract for inflammatory brain disease
This trial tests a natural substance called Calculus Bovis Sativus (CBS) to see if it helps people with certain inflammatory brain conditions like multiple sclerosis, neuromyelitis optica, MOGAD, or ADEM. The goal is to find out if it is safe and effective.
Wuhan, HubeiAges 18 years+ - NCT06474884Recruiting
Single blood thinner after shielded stent for brain aneurysm
This study is testing whether using only one blood-thinning medication (single antiplatelet therapy) after placing a special stent (Pipeline Flex with Shield) is safe and effective for treating unruptured brain aneurysms. It is for people who have already been on two blood thinners for a few days before the stent placement.
BeijingAges 18–80 - NCT06475118Recruiting
Blood tests and scans to measure muscle loss in liver cancer
This study looks at whether measuring certain proteins in your blood (myokines) can help detect muscle loss (sarcopenia) in people with liver cancer, and compares these blood tests to special CT scans. If you're newly diagnosed with liver cancer and have a CT scan already, you may be able to join.
ReimsAges 18 years+ - NCT06475651Recruiting
DNA patterns in rare prenatal diseases
This study looks at DNA patterns in fetuses or children with rare genetic conditions. It aims to better understand how these patterns relate to diseases that start before birth, which could help with diagnosis and future care.
ParisAges birth–18 years - NCT06475898Recruiting
Tracking Huntington's disease burden over time
This study follows people with Huntington's disease (or those who carry the gene) over time using online surveys. It aims to better understand how the disease progresses, which could help improve future care.
Rochester, New YorkAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,432 recruiting neurology studies from the U.S. registry right now, out of 19,532 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.