Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,432 recruiting studies in this area right now.
By phase
- Not applicable9,770
- Phase 2785
- Phase 1574
- Phase 3537
- Phase 4342
- Phase 1/Phase 2303
- Phase 2/Phase 3121
Top conditions
- Stroke846
- Parkinson Disease424
- Multiple Sclerosis343
- Alzheimer Disease340
- Dementia226
- Ischemic Stroke200
- Epilepsy196
- Obstructive Sleep Apnea155
- Insomnia153
- Spinal Cord Injuries153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke141
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis107
Leading sponsors
- Beijing Tiantan Hospital134
- Riphah International University126
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California674
- Massachusetts300
- New York291
- Florida274
- Texas267
- Maryland245
- Arizona214
- Alabama209
- Illinois190
- Pennsylvania177
Recruiting studies12,430 total
- NCT06506058Recruiting
Study on balance and brain in Parkinson's freezing of gait
This study looks at how the balance system and brain work together to cause freezing of gait in Parkinson's disease. By understanding these factors, researchers hope to find better ways to help people walk more steadily.
Minneapolis, MinnesotaAges 21–80 - NCT06506565RecruitingPhase 4
Low-dose ketamine for burn wound pain
This trial tests a low-dose ketamine infusion during burn wound dressing changes to see if it reduces pain. It might help people who are hospitalized with a thermal burn injury.
Memphis, TennesseeAges 18 years+ - NCT06506617Recruiting
Testing pneumonia patients in the emergency room
This trial studies a new testing method (HCAP-Pcr) for people with pneumonia caught in the hospital or other healthcare settings. Doctors will use a special lung washing procedure called bronchoalveolar lavage to quickly identify the cause of the infection, which could help guide treatment faster.
Florence, Tuscany/ItalyAges 18 years+ - NCT06506929Recruiting
Task Training for Advanced Multiple Sclerosis
This study tests a task-specific training program for people with advanced multiple sclerosis who use a wheelchair. The goal is to see if training on everyday activities can help them move more easily and feel better.
New York, New YorkAges 18–75 - NCT06507007Recruiting
Inner ear function in Turner syndrome
This study looks at why some people with Turner syndrome have inner ear problems. It uses MRI and CBCT scans to understand the genetic and epigenetic causes.
HerningAges 18–60 - NCT06507150Recruiting
AI-assisted migraine education for newly diagnosed patients
This study tests a new AI-powered learning tool to help people who were just diagnosed with migraine understand their condition better. You'll use the tool on your own device, and researchers will see if it's helpful and easy to use.
LuganoAges 18–65 - NCT06507228Recruiting
Simplified sleep apnea testing study
This trial is testing a new, automated way to diagnose obstructive sleep apnea (a condition where breathing stops and starts during sleep). If you have been referred from your primary care doctor for sleep apnea testing, you may be able to join.
LondonAges 18 years+ - NCT06507254Recruiting
Polyphenols and brain health in aging
This study tests whether eating more polyphenols (natural compounds in plants) can protect brain health in people at higher risk for Alzheimer's disease, especially if they currently eat a typical Western diet. Participants will be followed over time to see if changes in diet affect thinking and memory.
Los Angeles, CaliforniaAges 50 years+ - NCT06507488Recruiting
Daphnetin Capsule for Mild Cognitive Issues From Blood Vessels
This trial tests a capsule called daphnetin for people with mild thinking and memory problems linked to blood vessel health. The goal is to see if it helps improve or slow down these changes.
Shenyang, LiaoningAges 50–80 - NCT06507748Recruiting
Measuring pain with a finger device in NF1
This study tests a new way to measure pain and other sensations in people with NF1 using a device that clips onto a finger or toe. The device looks at how your pupil reacts to mild pulses, which may help doctors better understand your pain.
Washington D.C., District of ColumbiaAges 1–120 - NCT06508190Recruiting
Walking exercise for sleep apnea and fatty liver
This trial tests whether a simple walking program can help people who have both obstructive sleep apnea and non-alcoholic fatty liver disease. If you have these conditions and a BMI under 35, you may be able to join a free exercise program to see if it improves your health.
GizaAges 40–65 - NCT06508385Recruiting
How improvement affects fibromyalgia: A brain study
This study looks at how women with fibromyalgia perceive their improvement. It uses a brain scan (fMRI) to understand this better. The goal is to help improve treatments.
Istanbul, KartalAges 25–55 - NCT06508268Recruiting
Language, speech, and movement in early Alzheimer's
This study looks at how language, speech, and motor skills change in people with mild cognitive impairment (early memory problems) due to Alzheimer's disease, and in people with Alzheimer's disease. It also includes healthy older adults for comparison. The goal is to better understand these changes, which may help with earlier diagnosis.
GroningenAges Any age - NCT06509191RecruitingPhase 2/Phase 3
Melatonin for preventing delirium in older hospital patients
This trial tests if giving melatonin (a natural sleep hormone) can help prevent delirium (sudden confusion) in older adults who are hospitalized. It may help you if you are 65 or older and admitted to the hospital for general medical care.
MuscatAges 65 years+ - NCT06508801Recruiting
Blood flow restriction to improve balance in Parkinson's
This study tests whether gently restricting blood flow to your legs during exercise can help improve balance for people with Parkinson's disease. You will do simple leg exercises while wearing a special cuff, which may strengthen muscles and improve steadiness.
San Antonio, TexasAges 40–85 - NCT06509633Recruiting
Pain education and rehab for carpal tunnel syndrome
This study tests whether combining a special type of pain education with standard rehabilitation helps people with moderate to severe carpal tunnel syndrome feel better and improve hand function. It aims to help you understand your pain and recover.
Lahore, Punjab ProvinceAges 20–50 - NCT06509503RecruitingPhase 4
Effect of birth control pills on migraine
This study tests how combined oral contraceptive pills affect migraine in women. It will compare people who take these pills with those using non-hormonal methods like an IUD, to see if the pills help or change the migraine pattern.
Kafr ash ShaykhAges 18–55 - NCT06509698Recruiting
Virtual reality vs. Frenkel's exercises for stroke recovery
This trial compares virtual reality (VR) exercises to traditional Frenkel's exercises to see which helps stroke survivors improve balance and movement. You might benefit if you've had an ischemic stroke and haven't tried VR rehab before.
Lahore, Punjab ProvinceAges 40–65 - NCT06509646Recruiting
Tai Chi vs. Frenkel's exercises for stroke recovery
This study compares two types of gentle balance exercises (Tai Chi and Frenkel's exercises) to see which one helps people recover better after a stroke. It is for stroke survivors who are 50+ and at least 3 months past their stroke.
Lahore, Punjab ProvinceAges 50 years+ - NCT06510140Recruiting
Brain monitoring and frailty to predict confusion after surgery in older adults
This study tests if monitoring your brain waves during surgery and checking your frailty level can help predict whether you might become confused after surgery. It aims to improve care for older adults having major non-cardiac operations.
Saint-EtienneAges 75 years+ - NCT06510283RecruitingPhase 2
Taitacept for refractory or recurrent autoimmune encephalitis
This trial tests a new drug called Taitacept for people with autoimmune encephalitis (brain inflammation caused by the immune system) that has not improved with standard treatments or has returned. The goal is to see if Taitacept can help control symptoms.
Beijing, Beijing MunicipalityAges 14 years+ - NCT06510426RecruitingPhase 2
Early Interferon-beta for West Nile Virus
This trial tests if giving early treatment with interferon-beta can help patients with West Nile virus (WNV) infection, especially those at higher risk of serious illness. It includes older adults, people with severe neurological symptoms, and those with weakened immune systems.
Tel AvivAges 18 years+ - NCT06510582RecruitingPhase 1/Phase 2
Bevacizumab injection for chronic subdural hematoma
This trial tests if injecting bevacizumab into the artery that supplies the covering of the brain can help treat chronic subdural hematoma (a slow-growing collection of blood on the brain's surface). It may offer an alternative to surgery for some patients.
Camden, New JerseyAges 18 years+ - NCT06510751Recruiting
CGRP and substance P in meningitis ICU patients
This study measures two natural chemicals (CGRP and substance P) in adult ICU patients with suspected meningitis. It aims to see if their levels help diagnose or understand meningitis better.
AntalyaAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,432 recruiting neurology studies from the U.S. registry right now, out of 19,532 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.