Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,432 recruiting studies in this area right now.
By phase
- Not applicable9,770
- Phase 2785
- Phase 1574
- Phase 3537
- Phase 4342
- Phase 1/Phase 2303
- Phase 2/Phase 3121
Top conditions
- Stroke846
- Parkinson Disease424
- Multiple Sclerosis343
- Alzheimer Disease340
- Dementia226
- Ischemic Stroke200
- Epilepsy196
- Obstructive Sleep Apnea155
- Insomnia153
- Spinal Cord Injuries153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke141
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis107
Leading sponsors
- Beijing Tiantan Hospital134
- Riphah International University126
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California674
- Massachusetts300
- New York291
- Florida274
- Texas267
- Maryland245
- Arizona214
- Alabama209
- Illinois190
- Pennsylvania177
Recruiting studies12,430 total
- NCT06500481RecruitingPhase 3
Proton vs standard radiation for cancer spread to brain/spine lining
This trial compares a newer type of radiation (proton therapy) to standard radiation for people whose breast or lung cancer has spread to the lining of the brain and spinal cord. It aims to see if proton therapy can better control the disease while causing fewer side effects.
Phoenix, ArizonaAges 18 years+ - NCT06500728Recruiting
Vision involvement in giant cell arteritis
This study looks at how vision is affected in people with giant cell arteritis (GCA) -- a condition where blood vessels become inflamed. It compares those with GCA-related vision loss to people who have similar vision problems but not from GCA, to better understand and treat these eye issues.
Milan, LombardyAges 18 years+ - NCT06501079Recruiting
Pain relief study: adding dexamethasone or magnesium to a nerve block for kidney removal
This study compares two different medications (dexamethasone and magnesium) added to a standard painkiller used in a nerve block for patients having one kidney removed. The goal is to find out which combination provides better pain relief after surgery.
CairoAges 18–65 - NCT06501495Recruiting
Brain waves and memory in aging and Alzheimer's
This study looks at how brain waves (EEG) change during normal aging and early Alzheimer's disease. It compares three groups: people with early-stage Alzheimer's, healthy older adults, and healthy young adults. The goal is to understand how memory and thinking problems relate to slow brain wave activity.
ParisAges 18–85 - NCT06501391RecruitingPhase 2
Brain radiation plus chemo-immunotherapy for untreated NSCLC with stable brain metastases
This trial tests whether combining brain radiation with chemotherapy and immunotherapy can help people with advanced lung cancer that has spread to the brain but has not yet been treated. It is for those whose tumors do not have certain gene mutations (EGFR, ALK, ROS1).
ShanghaiAges 18 years+ - NCT06501430Recruiting
Treatment for shin splints in amateur football players
This trial tests two muscle-relaxation techniques to reduce pain from shin splints in amateur football players. It may help you recover faster and get back to playing.
Lahore, Punjab ProvinceAges 18–30 - NCT06501521Recruiting
Non-invasive brain tumor testing and monitoring
This study is testing a new, non-invasive way to diagnose and monitor brain tumors. It may offer a less risky option compared to traditional biopsies.
OlomoucAges 18–99 - NCT06502015Recruiting
Biomarkers in nervous system autoimmune diseases
This study looks for biomarkers (biological clues) in people with autoimmune diseases of the nervous system. It aims to discover better ways to diagnose and treat these conditions.
WuhanAges 18 years+ - NCT06501950Recruiting
Measuring silent MS progression with advanced tests
This study is looking for people with MS who are already on a monoclonal antibody therapy. It aims to measure subtle signs of disease progression using advanced tests, even if you feel stable.
Düsseldorf, North Rhine-WestphaliaAges 18 years+ - NCT06502951Recruiting
Treatment for headache and neck pain after whiplash
This study tests if combining spinal manipulation and dry needling can reduce headache and neck pain in people who have had whiplash from a car accident. It may help if you've had symptoms for more than 4 weeks.
Montgomery, AlabamaAges 18–65 - NCT06503016RecruitingPhase 3
Phosphocreatine for medical emergency team patients
This study tests if a medicine called phosphocreatine helps people in the hospital who have a serious heart or lung emergency. It aims to see if the medicine can improve recovery and prevent further complications.
MilanAges 18 years+ - NCT06503172RecruitingPhase 2
Job's Tear for muscle health in older adults
This trial tests if whole grain Job's Tear can improve muscle health, blood sugar, and cholesterol in people aged 60-95 who may feel weak or have slowed down. It looks at whether adding this grain to your diet helps with daily energy and walking speed.
TaipeiAges 60–95 - NCT06503328Recruiting
Cluster headache microRNA study
This study aims to understand how certain tiny molecules in the blood (called microRNAs) are different in people with cluster headache. It could help find better ways to diagnose or treat this condition.
PaviaAges 18–65 - NCT06503484Recruiting
Brain training with light for stroke arm recovery
This trial tests whether a brain-computer interface (BCI) using near-infrared light can help stroke survivors improve hand and arm movement. You'll receive a type of brain training called neurofeedback during the study.
Hong Kong, Hong KongAges 18–75 - NCT06503848Recruiting
Migraine attack treatment response biomarkers study
This study looks at how your body responds to migraine attack treatment, by tracking symptoms and blood markers. It may help find better ways to treat migraines in the future.
BarcelonaAges 18–45 - NCT06504238Recruiting
Non-invasive monitoring for acute brain injury
This trial tests special cameras and sensors that check your brain without surgery. It may help doctors watch for brain swelling and other problems more safely.
Boston, MassachusettsAges 18 years+ - NCT06504537Recruiting
Theragun vs compression therapy for migraine relief
This study compares two handheld massage devices—a percussive therapy device (Theragun) and a compression therapy device—to see which works better for migraine pain. If you have frequent migraines without aura, this could help you find a simple, drug-free treatment option.
Lahore, Punjab ProvinceAges 18–65 - NCT06504576RecruitingPhase 2
Testing cilostazol to clear brain bleed
This clinical trial tests whether a medication called cilostazol can help the body reabsorb a brain bleed (intracerebral hemorrhage) more quickly. It is for adults with a small bleed in a specific part of the brain (thalamus or basal ganglia) who are otherwise in good health.
Taipei, Not Required For This CountryAges 20–80 - NCT06504511Recruiting
SCN1A gene study for epilepsy patients in the UK
This study aims to better understand SCN1A-related epilepsies by following patients over time. Researchers hope to learn more about how the condition progresses to help develop future treatments.
GlasgowAges Any age - NCT06504836Recruiting
Walking feedback in stroke recovery
This study tests a special walking feedback system (like a video game for your legs) for people who had a stroke at least 6 months ago. It aims to improve walking quality, such as how smoothly and evenly you step.
TaipeiAges 20–80 - NCT06505421Recruiting
Eccentric exercise for fatigue in multiple sclerosis
This study tests whether a specific type of leg exercise (called eccentric exercise) can help reduce fatigue in people with Multiple Sclerosis. It involves walking and other exercises to see if they improve how tired you feel.
New York, New YorkAges 18–75 - NCT06505447Recruiting
Sleep study for kids in the PICU
This study looks at how sleep and body rhythms are affected when a child is in the pediatric intensive care unit (PICU). It may help doctors find ways to improve sleep for children who are in the hospital.
Buffalo, New YorkAges 3–6 - NCT06505460Recruiting
Brain stimulation for Parkinson's freezing of gait
This study is testing if two brain-stimulation treatments—deep brain stimulation (DBS) or focused ultrasound—can help reduce freezing of gait (a common, frustrating symptom where your feet feel stuck when walking) in people with Parkinson's. Researchers will use brain scans and electrical recordings to understand how these treatments work.
TaichungAges 20–90 - NCT06505564Recruiting
VR avatar therapy for hearing voices
This study tests a virtual reality (VR) therapy where you talk to a computer-generated avatar that represents the main voice you hear. The goal is to help you feel more in control.
BudapestAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,432 recruiting neurology studies from the U.S. registry right now, out of 19,532 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.