Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,462 recruiting studies in this area right now.
By phase
- Not applicable9,797
- Phase 2786
- Phase 1574
- Phase 3538
- Phase 4342
- Phase 1/Phase 2304
- Phase 2/Phase 3121
Top conditions
- Stroke854
- Parkinson Disease424
- Multiple Sclerosis342
- Alzheimer Disease340
- Dementia226
- Ischemic Stroke199
- Epilepsy196
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia152
- Traumatic Brain Injury152
- Sarcopenia148
- Acute Ischemic Stroke141
- Cerebral Palsy130
- Mild Cognitive Impairment129
- Pain Management114
- Migraine113
- Amyotrophic Lateral Sclerosis107
Leading sponsors
- Beijing Tiantan Hospital134
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing95
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- Cairo University63
Where studies are running
- California675
- Massachusetts301
- New York292
- Florida277
- Texas267
- Maryland244
- Arizona216
- Alabama211
- Illinois193
- Pennsylvania177
Recruiting studies12,460 total
- NCT06553235Recruiting
App-based sleep and memory help for breast cancer survivors
This study tests whether an app-based program can improve sleep and thinking problems (like concentration and memory) in people who finished breast cancer treatment 1-5 years ago. If you have trouble sleeping and/or notice changes in your memory or focus, this trial may be able to help.
Aarhus NAges 18 years+ - NCT06553339RecruitingPhase 1
A study of HS-10516 for VHL syndrome tumors
This trial tests a new drug called HS-10516 in people with VHL syndrome or advanced kidney cancer. The goal is to see if the drug can shrink tumors and what side effects it might have.
Beijing, Beijing MunicipalityAges 18–80 - NCT06553365RecruitingPhase 2
Study of FCN-159 for NF2 nerve sheath tumors
This trial tests an oral drug called FCN-159 for people with NF2-related nerve sheath tumors that cannot be fully removed by surgery or have come back after surgery. It aims to see if the drug can shrink or slow the growth of these tumors.
Beijing, Beijing MunicipalityAges 16 years+ - NCT06553976Recruiting
Research network for hereditary spastic paraplegia
This trial aims to build a research network and gather information from people with two genetic types of hereditary spastic paraplegia (SPG4 and SPG5A). It will help doctors better understand these conditions and improve care.
Miami, FloridaAges Any age - NCT06553625Recruiting
RF ablation study for pain or CNS conditions
This study observes how well a Boston Scientific radiofrequency (RF) system works for treating pain or central nervous system (CNS) conditions. It helps researchers understand real-world benefits for patients scheduled for this procedure.
CologneAges Any age - NCT06554106Recruiting
Electrical stimulation for fibromyalgia pain
This trial tests whether a gentle electrical stimulation therapy can reduce pain and improve daily life in people with fibromyalgia. It aims to offer a drug-free option to manage symptoms.
ElâzığAges 18–65 - NCT06554171Recruiting
Hippotherapy Simulator for kids with cerebral palsy
This study uses a special horseback-riding simulator to see if it can help children with cerebral palsy improve their trunk control and arm function. It's designed for kids who have tightness on one side of the body and can cooperate with instructions.
ElâzığAges 6–18 - NCT06554288RecruitingPhase 1
Trihexyphenidyl for dystonia in cerebral palsy
This study tests how a medicine called trihexyphenidyl works in children with dystonic cerebral palsy, a condition that causes muscle spasms. Researchers want to learn if a child’s genes affect how the medicine works and how the body processes it.
Kansas City, MissouriAges 5–17 - NCT06554340Recruiting
Exercise study for multiple sclerosis with high blood pressure
This study tests if exercise can improve blood vessel health and daily function in people with multiple sclerosis (MS) who also have high blood pressure. It may help you move better and feel better.
Boston, MassachusettsAges 18 years+ - NCT06554496Recruiting
Xanthine Oxidoreductase Levels in New Sleep Apnea Patients
This study measures a substance called XOR in the blood of people who have just been diagnosed with obstructive sleep apnea but haven't started treatment yet. It aims to see if XOR levels are linked to sleep apnea.
Nanjing, JiangsuAges 18–80 - NCT06554665Recruiting
High-Intensity Interval Training for Stroke Recovery
This study tests whether a high-intensity interval training (HIIT) program—short bursts of intense exercise with rest periods—can help improve walking, balance, and daily function in people who have had a stroke. It is for adults who are 50 to 80 years old, had their first stroke 1 to 5 years ago, and can walk at least 10 meters on their own.
KowloonAges 50–80 - NCT06554834Recruiting
Osteopathic technique's effect on nervous system activity
This study tests whether an osteopathic technique can affect your autonomic nervous system, which controls things like heart rate and digestion. It's for healthy adults aged 20 to 60 who are not currently in physical therapy or osteopathy.
Wołomin, PrądzyńskiegoAges 20–65 - NCT06555016Recruiting
Balance training intensity after stroke
This study tests different levels of balance training in people who had a stroke more than 6 months ago. It aims to find the best exercise intensity to improve balance and prevent falls.
Toronto, OntarioAges 20 years+ - NCT06555406Recruiting
Healthy lifestyle study for bipolar disorder with sleep issues
This study tests a healthy lifestyle program for people with bipolar disorder who have sleep or schedule problems. It aims to see if changing daily habits can help improve mood and sleep.
Berkeley, CaliforniaAges 18–65 - NCT06555523Recruiting
Trigger point shots for muscle pain syndrome
This trial tests if injecting trigger points in the neck and shoulder muscles can relieve pain in people with fibromyalgia and chronic myofascial pain syndrome. It may help reduce muscle tightness and improve function.
ElâzığAges 18–65 - NCT06555588Recruiting
Supportive talk therapy for advanced cancer symptoms
This study tests a supportive talk therapy program (called Engage) delivered via video calls. It aims to help people with advanced cancer manage tough symptoms like pain, fatigue, and distress and improve daily functioning.
Durham, North CarolinaAges 18 years+ - NCT06556043Recruiting
Brain stimulation to improve ankle control in adults with and without stroke
This study uses mild brain stimulation (tDCS) to see if it can help middle-aged and older adults—both healthy and those who have had a stroke—learn ankle movements better. It tests whether stimulating different brain regions can improve motor skills and brain connections.
TaipeiAges 40–80 - NCT06556446Recruiting
Clot-busting drug after stroke if on blood thinner
This study looks at whether giving a clot-busting medicine (IV thrombolysis) is safe and effective for people who have had a stroke and also recently took a direct oral anticoagulant (DOAC). If you've taken a DOAC in the last 48 hours, this trial may help doctors decide the best treatment for you.
InnsbruckAges 18 years+ - NCT06556394RecruitingPhase 1
Testing RAG-17 for ALS with SOD1 gene mutation
This trial tests a new drug, RAG-17, for people with ALS who have a specific SOD1 gene mutation. The goal is to see if it's safe and how it affects the body, which may help slow the disease.
BeijingAges 18 years+ - NCT06556615Recruiting
Quality of life in classical homocystinuria
This study surveys how classical homocystinuria (CBS deficiency) affects daily life and well-being. It includes patients age 8 and up, parents of younger or cognitively impaired children, and medical experts.
ZurichAges 8 years+ - NCT06556693Recruiting
Study of a new device for severe sleep apnea
This study tests if a new device can help people with severe sleep-disordered breathing (like sleep apnea). It may be an option if you have no or well-managed heart failure and are able to follow study procedures.
Scottsdale, ArizonaAges 22 years+ - NCT06557135Recruiting
Arm vs. Leg Artery for Carotid Stenting
This study compares two ways to reach the blocked neck artery during a stent procedure: through an artery in your arm versus one in your groin. The goal is to see which route is safer and works better for patients who need this treatment.
Nanjing, JiangsuAges 18 years+ - NCT06557369Recruiting
New light therapy for intermediate age-related macular degeneration
This trial tests a new light-based treatment for intermediate age-related macular degeneration (AMD), a common eye condition that can lead to vision loss. The goal is to see if it is safe and helps slow down the disease.
BergamoAges 50 years+ - NCT06557720Recruiting
Imaging study for hard-to-control epilepsy
This study looks at how different brain scans (like MRI, PET, and EEG) can help find the exact spot where seizures start in people whose epilepsy hasn't been controlled by medicines. It aims to better understand drug-resistant epilepsy so doctors can plan more accurate treatments.
Xi'anAges 18–65
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,462 recruiting neurology studies from the U.S. registry right now, out of 19,649 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.