Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,462 recruiting studies in this area right now.
By phase
- Not applicable9,797
- Phase 2786
- Phase 1574
- Phase 3538
- Phase 4342
- Phase 1/Phase 2304
- Phase 2/Phase 3121
Top conditions
- Stroke854
- Parkinson Disease424
- Multiple Sclerosis342
- Alzheimer Disease340
- Dementia226
- Ischemic Stroke199
- Epilepsy196
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia152
- Traumatic Brain Injury152
- Sarcopenia148
- Acute Ischemic Stroke141
- Cerebral Palsy130
- Mild Cognitive Impairment129
- Pain Management114
- Migraine113
- Amyotrophic Lateral Sclerosis107
Leading sponsors
- Beijing Tiantan Hospital134
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing95
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- Cairo University63
Where studies are running
- California675
- Massachusetts301
- New York292
- Florida277
- Texas267
- Maryland244
- Arizona216
- Alabama211
- Illinois193
- Pennsylvania177
Recruiting studies12,460 total
- NCT06582355Recruiting
Brain training with MRI for Parkinson's disease
This study tests whether a brain-training technique called neurofeedback can help people with Parkinson's disease. You will learn to control certain brain signals while having an MRI scan, which may improve your symptoms.
CologneAges 18 years+ - NCT06582706RecruitingPhase 1/Phase 2
Vitamin B3 (niacin) for Alzheimer's disease
This study tests if nicotinic acid (a form of vitamin B3) can help people with mild to moderate Alzheimer's disease. It involves taking a daily pill, having a lumbar puncture, and regular check-ups to see if the vitamin improves thinking and memory.
Indianapolis, IndianaAges 60–85 - NCT06582940RecruitingPhase 2
MRI-guided radiation for lung cancer with brain metastases
This trial tests a new way to deliver radiation to brain metastases from non-small cell lung cancer, using MRI scans to guide the treatment and reduce the area exposed. The goal is to see if this approach is safe and effective while possibly lowering side effects.
Guangzhou, GuangdongAges 18–75 - NCT06583122Recruiting
Nerve block study for occipital pain or migraine
This trial tests if using ultrasound-guided heat (radiofrequency ablation) on the occipital nerve can reduce headache pain. It is for people with occipital neuralgia or migraine pain at the back of the head who haven't had enough relief from oral medications.
Kansas City, KansasAges 18–80 - NCT06583772Recruiting
Virtual reality hand test for stroke recovery
This study tests a virtual reality version of the 9-hole peg test to measure hand function in stroke patients. It could provide a fun and accurate way to track your recovery.
AnkaraAges 18–70 - NCT06584045Recruiting
Testing a bile-based treatment for adult encephalitis
This study tests a natural bile-derived medicine (Calcus Bovis Sativus) to see if it can help adults with new or recent brain inflammation (encephalitis). It focuses on people whose encephalitis is caused by the immune system or a virus, and who have not fully recovered.
Wuhan, HubeiAges 18 years+ - NCT06584084Recruiting
Testing a new surface EMG device for muscle and nerve conditions
This study tests a new device that measures muscle and nerve signals using non-invasive (surface) electrodes. It aims to see if this device can replace the standard needle EMG test, which is more painful. The trial includes both healthy volunteers and patients with muscle or nerve disorders.
LuganoAges 18 years+ - NCT06584110Recruiting
Buddy-up exercise program for dementia and caregiver
This study tests a buddy-up program where a person with mild to early moderate dementia and their family caregiver do physical activities together using video calls. It aims to see if exercising together helps both their health and well-being.
Hong KongAges 18 years+ - NCT06584123Recruiting
Molecular imaging of pituitary adenoma with 18F-FET PET
This study uses a special PET scan (18F-FET) to get clearer images of pituitary adenomas (non-cancerous growths at the base of the brain). It is for people who have already had one type of PET scan and can help doctors understand the tumor better without invasive procedures.
Cambridge, CambridgeshireAges 18–100 - NCT06584357Recruiting
Digital and blood markers linked to brain scans in older adults
This study is looking for older adults (60–90) who are either cognitively normal, have mild cognitive impairment (MCI), or have mild-to-moderate Alzheimer's dementia. It aims to see how digital tests and blood-based markers relate to brain scans (amyloid and tau PET). You will need a study partner, undergo MRI and PET scans, and give blood samples.
Atlantis, FloridaAges 60–90 - NCT06584409Recruiting
Laser Acupuncture vs Standard for Migraine – Blood Test Study
This trial tests whether laser acupuncture can help migraines by checking two substances in your blood (MMP2 and CGRP). You may be able to join if you have migraines and are not pregnant.
Taichung, TaichangAges 18 years+ - NCT06584565Recruiting
Predicting stroke recovery and risk using blood and stool tests
This study uses advanced analysis of your blood and stool samples to better predict how you will recover from a stroke and whether it might happen again. It aims to help doctors personalize your care after a stroke.
Guangzhou, GuangdongAges 18–75 - NCT06584591Recruiting
Balance training study for people with traumatic brain injury
This study tests a new balance training program called NEUROBALANCE to help improve postural control in people who have had a traumatic brain injury. It uses a non-invasive brain stimulation technique (TMS) to see if it can help improve balance and walking.
West Orange, New JerseyAges 18–75 - NCT06584851Recruiting
3D muscle study in children with cerebral palsy
This study uses a special 3D microscope to look at muscle structure in children with cerebral palsy. It aims to understand muscle stiffness by comparing tiny muscle samples taken during a scheduled procedure that already requires general anesthesia.
Leuven, Vlaams-BrabantAges 2–9 - NCT06584864Recruiting
Ultrasound for better lumbar puncture in children
This study tests whether using a bedside ultrasound (a quick, painless scan) helps doctors perform a lumbar puncture (spinal tap) more easily and safely in children. It may help children who need this procedure.
WarsawAges Up to 18 years - NCT06585384RecruitingPhase 1
Safety of etanercept with contrast ultrasound for Alzheimer's
This study tests whether combining a drug called etanercept with repeated contrast ultrasound is safe for people with mild Alzheimer's. It aims to see if this approach can help slow the disease.
ParisAges 50–85 - NCT06585228Recruiting
Heart CT vs ultrasound to find clots after stroke
This study compares two ways to look for blood clots in the heart after a stroke: a heart CT scan and an ultrasound done through the food pipe. It aims to see if the CT scan can spot clots just as well as the more invasive ultrasound.
Amsterdam, North HollandAges 18 years+ - NCT06585449RecruitingPhase 1
Study of ALN-HTT02 for Huntington's disease
This trial tests an experimental drug called ALN-HTT02 for people with Huntington's disease. The goal is to see if it can help manage symptoms. Participants must have stage 2 or early stage 3 Huntington's disease.
EdmontonAges 25–70 - NCT06585618Recruiting
Pediatric Deep Brain Stimulation Registry
This study creates a list of children who already have or plan to get Deep Brain Stimulation (DBS) to see how it helps with movement problems. Joining helps doctors learn more about how DBS works in kids.
Boston, MassachusettsAges birth–18 years - NCT06585605Recruiting
Study of epilepsy and movement disorder genes in children
This study looks at children with epilepsy and movement disorders to better understand the genes involved. It aims to help doctors recognize and treat these conditions more effectively.
Boston, MassachusettsAges birth–18 years - NCT06585748Recruiting
Lidocaine spray for comfort during bladder catheterization
This trial tests if using lidocaine spray can make bladder catheterization more comfortable for men. If you are an adult male who needs this procedure, this study may help reduce discomfort.
Ankara, AnkaraAges 18–92 - NCT06585943Recruiting
Cycling therapy for stroke recovery
This study tests a special cycling exercise program designed to help people who have had a stroke regain arm and leg movement. It aims to see if this focused cycling therapy can improve recovery and reduce healthcare costs.
Cleveland, OhioAges 18–85 - NCT06586177Recruiting
Study on Long-Term Effects of B Cell Therapies for MS
This study looks at how B cell therapies (a type of medicine for MS) create a long-lasting effect in people with relapsing-remitting multiple sclerosis. It aims to understand how these treatments work over time so doctors can better predict benefits and risks.
DüsseldorfAges 18–60 - NCT06586268Recruiting
Sleep changes after surgery in people with sleep apnea
This study looks at how sleep patterns change in the first three nights after surgery for people who have obstructive sleep apnea (OSA). It aims to understand how anesthesia and sleep apnea severity affect sleep quality during recovery.
Amsterdam, North HollandAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,462 recruiting neurology studies from the U.S. registry right now, out of 19,649 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.