Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,462 recruiting studies in this area right now.
By phase
- Not applicable9,797
- Phase 2786
- Phase 1574
- Phase 3538
- Phase 4342
- Phase 1/Phase 2304
- Phase 2/Phase 3121
Top conditions
- Stroke854
- Parkinson Disease424
- Multiple Sclerosis342
- Alzheimer Disease340
- Dementia226
- Ischemic Stroke199
- Epilepsy196
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia152
- Traumatic Brain Injury152
- Sarcopenia148
- Acute Ischemic Stroke141
- Cerebral Palsy130
- Mild Cognitive Impairment129
- Pain Management114
- Migraine113
- Amyotrophic Lateral Sclerosis107
Leading sponsors
- Beijing Tiantan Hospital134
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing95
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- Cairo University63
Where studies are running
- California675
- Massachusetts301
- New York292
- Florida277
- Texas267
- Maryland244
- Arizona216
- Alabama211
- Illinois193
- Pennsylvania177
Recruiting studies12,460 total
- NCT06620172Recruiting
Comparing two methods of nerve treatment for facial pain
This trial tests two image-guided procedures to treat severe facial pain from trigeminal neuralgia. It compares using a CT scan versus an X-ray video to guide a needle that heats the nerve to stop pain signals.
Zagazig, Sharqia ProvinceAges 18–60 - NCT06620380RecruitingPhase 2
Testing tumor samples to find the best drug for brain metastases
This trial tests tumor samples from brain metastases to see which drug might work best for you. It aims to guide your next treatment when standard options are limited.
BaselAges 18 years+ - NCT06620601Recruiting
Digital technology for sleep and homelessness
This study explores how digital tools can help improve sleep for people living in shelters. It aims to test whether wearable devices or apps can support better sleep habits and health.
Toronto, OntarioAges 18 years+ - NCT06620809RecruitingPhase 1
Safety and efficacy of NouvSoma001 for NMOSD
This trial tests a new treatment called NouvSoma001 for neuromyelitis optica spectrum disorder (NMOSD), a condition where the immune system attacks the optic nerves and spinal cord. It looks at whether the drug is safe and helps people who have had a recent attack with severe pain, trouble walking, or bladder/bowel problems.
Wuhan, HubeiAges 18–65 - NCT06621121Recruiting
Comparing two clot-busting drugs for stroke within 4.5 hours
This study compares two medications, tenecteplase and alteplase, to see which works better at dissolving blood clots in people having an ischemic stroke. You may join if you can get treatment within 4.5 hours of when your symptoms started.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT06621407Recruiting
Best drainage method after burr hole for chronic subdural hematoma
This trial compares different ways to drain a chronic subdural hematoma after a single burr hole procedure. It aims to find which method works best to help your brain recover.
AalborgAges 18 years+ - NCT06621511Recruiting
OurSleepKit: Helping couples stick with CPAP therapy
This study tests a program called OurSleepKit designed to help people with sleep apnea and their partners use CPAP therapy consistently. It may be a good fit if you and your partner live together and want to improve your sleep health together.
Boston, MassachusettsAges 18 years+ - NCT06621771Recruiting
Piano therapy for hand recovery after a first stroke
This study tests whether playing the piano (for the first time) can help improve arm and hand movement after a stroke. You would practice piano exercises to regain dexterity and coordination.
Laval, QuebecAges 40–74 - NCT06622044Recruiting
Vision therapy vs prism for small-angle eye turn
This trial compares two non-surgical treatments—vision therapy exercises and prism glasses—for people with a recent, constant inward eye turn (esotropia) of a small angle. The goal is to see which approach works better to straighten the eyes.
ShanghaiAges 10–40 - NCT06622655Recruiting
Home use of Agilik for children with cerebral palsy
This trial tests if using a device called Agilik at home can help children with cerebral palsy who have a crouched walking pattern. Crouch gait is when knees stay bent while walking, and the Agilik may help improve movement.
Bosisio Parini, LeccoAges 5–17 - NCT06623123RecruitingPhase 3
Phone app vs. talking therapy for tinnitus relief
This trial compares a smartphone app called Oto to standard talking therapies for treating tinnitus. If you have had tinnitus for at least 3 months and can use an app, this study may help you find relief.
Stevenage, HertfordshireAges 18 years+ - NCT06623188Recruiting
Ear stimulation for treating episodic migraine
This trial tests if a device that gently stimulates the ear can reduce migraine attacks. It is for adults with regular migraines who have not had success with at least two preventive medications.
MarseilleAges 18–60 - NCT06623357Recruiting
Caregiver training for babies with brachial plexus birth injury
This study tests a training program for parents of infants with brachial plexus birth injury (a nerve injury around the shoulder that can limit arm movement). The program aims to help caregivers learn exercises to improve their baby's arm function.
St. Petersburg, FloridaAges 18 years+ - NCT06623864Recruiting
Person-centered care training for nursing assistants
This trial tests a new care model for nursing assistants and similar workers in residential care settings. It aims to improve how care is provided by focusing on the person's needs and preferences.
Burgos, BurgosAges 60 years+ - NCT06623890Recruiting
Long-term safety of omaveloxolone for Friedreich's ataxia
This study looks at the long-term safety of omaveloxolone (BIIB141) for people with Friedreich's ataxia. You can join if you are just starting this medicine or have been taking it for less than a year.
Los Angeles, CaliforniaAges 16 years+ - NCT06624371RecruitingPhase 1
Atovaquone with radiation for children with brain tumors
This trial tests adding atovaquone to standard radiation therapy for children with aggressive brain tumors like high-grade glioma (a fast-growing brain cancer) or medulloblastoma. The goal is to see if this drug, which targets energy production in cancer cells, can make radiation work better.
Atlanta, GeorgiaAges 2–25 - NCT06624436RecruitingPhase 4
Study of anti-inflammatory drugs in brief, controlled inflammation
This study tests how three different anti-inflammatory drugs (dexamethasone, tocilizumab, and anakinra) affect the body's immune response during a controlled, short-term inflammation. It is for healthy young men who can safely receive an experimental substance that temporarily mimics an infection.
Nijmegen, GelderlandAges 18–35 - NCT06624488Recruiting
Brain injury markers after cardiac arrest and outlook
This study looks at certain proteins in the fluid around the brain and in the blood after a cardiac arrest. These proteins may help doctors predict how the patient will recover, which could guide their care.
BeijingAges 18–80 - NCT06624592RecruitingPhase 3
Anesthesia for preventing agitation in children after surgery
This study compares two types of anesthesia gas (sevoflurane/dexmedetomidine vs. isoflurane) to see which helps prevent agitation or confusion when children wake up after surgery. It is for children ages 2–7 having certain ear, nose, throat, eye, or urology procedures with an IV and breathing tube.
Rochester, MinnesotaAges 2–7 - NCT06624969Recruiting
Virtual reality for reducing orthopedic pain
This trial tests if using a virtual reality headset can help reduce pain for people in the hospital with a broken bone. You would use the headset while resting or during procedures to see if it eases discomfort.
Jacksonville, FloridaAges 18 years+ - NCT06625112Recruiting
STXBP1 disorder clinical trial readiness study
This study is for people with a confirmed STXBP1 genetic change to help prepare for future clinical trials. It collects information about the condition to better understand it.
AntwerpAges Any age - NCT06625281Recruiting
Comparing two head exercises for dizziness from BPPV
This study tests if adding special head exercises (Brandt-Daroff) to two different repositioning maneuvers (Epley or Semont-Plus) helps reduce dizziness and improve quality of life in people with a common inner ear condition called BPPV.
IslamabadAges 20–65 - NCT06625684Recruiting
Long-term study for glioblastoma patients
This study tracks people with glioblastoma (a type of aggressive brain tumor) over time to understand what affects their health and quality of life. If you take part, you'll fill out online surveys to help researchers learn how to improve care.
Durham, North CarolinaAges 18 years+ - NCT06626308Recruiting
Early signs in Huntington’s gene carriers study
This study looks for early changes in the body and brain of people who carry the Huntington’s disease gene but don’t yet have symptoms. It may help find better ways to track the disease early.
GrenobleAges 18–70
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,462 recruiting neurology studies from the U.S. registry right now, out of 19,649 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.