Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,462 recruiting studies in this area right now.
By phase
- Not applicable9,797
- Phase 2786
- Phase 1574
- Phase 3538
- Phase 4342
- Phase 1/Phase 2304
- Phase 2/Phase 3121
Top conditions
- Stroke854
- Parkinson Disease424
- Multiple Sclerosis342
- Alzheimer Disease340
- Dementia226
- Ischemic Stroke199
- Epilepsy196
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia152
- Traumatic Brain Injury152
- Sarcopenia148
- Acute Ischemic Stroke141
- Cerebral Palsy130
- Mild Cognitive Impairment129
- Pain Management114
- Migraine113
- Amyotrophic Lateral Sclerosis107
Leading sponsors
- Beijing Tiantan Hospital134
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing95
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- Cairo University63
Where studies are running
- California675
- Massachusetts301
- New York292
- Florida277
- Texas267
- Maryland244
- Arizona216
- Alabama211
- Illinois193
- Pennsylvania177
Recruiting studies12,460 total
- NCT06626919RecruitingPhase 1
A cell therapy trial for generalized myasthenia gravis
This trial tests a new cell therapy called anitocabtagene autoleucel (anito-cel) for people with generalized myasthenia gravis (gMG) that is not well controlled with current treatments. The goal is to see if it can reduce symptoms and improve quality of life.
Los Angeles, CaliforniaAges 18 years+ - NCT06627387Recruiting
Balance training with augmented reality for home rehab
This study tests a low-cost balance training platform that uses augmented reality to help people with balance problems from stroke or other brain conditions. It aims to see if the platform is easy and safe to use at home with a training partner.
Barcelona, BarcelonaAges 18 years+ - NCT06627491Recruiting
How imagined muscle contractions affect your muscles and brain
This study looks at how imagining different types of muscle contractions (fast vs. slow) might change your muscle function and how your brain controls them. It could help us understand new ways to improve strength without actual exercise.
Kennesaw, GeorgiaAges 18–30 - NCT06628128RecruitingPhase 3
Long-term study of JNT-517 for people with PKU
This study tests a new medicine called JNT-517 for people with phenylketonuria (PKU) over a long period. It aims to see if the drug can help manage PKU safely and effectively.
Gainesville, FloridaAges 4 years+ - NCT06628349Recruiting
Protein Study for Older Adults with COPD
This study looks at how two types of protein drinks (one from plants, one from whey/dairy) affect muscle and metabolism in older adults who have COPD. You'll lie in a bed for several hours while researchers measure your body's response to the protein. The goal is to find which protein might better help maintain muscle strength.
College Station, TexasAges 50–95 - NCT06628414Recruiting
Brain stimulation study for tinnitus relief
This study tests whether a gentle brain stimulation technique called tDCS can help people with tinnitus. Volunteers will receive either real or fake stimulation to see if it reduces tinnitus symptoms.
NottinghamAges 18 years+ - NCT06628505Recruiting
Auditory training study for people with mild brain injury
This trial tests a type of listening training to see if it can help people who have had a mild traumatic brain injury (concussion). It may improve how your brain processes sound.
San Antonio, TexasAges 18–55 - NCT06628531Recruiting
Lung health in patients with severe brain bleed
This trial looks at how a severe brain bleed (subarachnoid hemorrhage) might affect lung function and hyaluronic acid buildup in the lungs. It aims to find better ways to protect breathing for patients in the intensive care unit.
TianjinAges 18–80 - NCT06628687Recruiting
Study checking omaveloxolone health effects during pregnancy and breastfeeding
This study follows people with Friedreich's ataxia who took omaveloxolone during pregnancy or while breastfeeding, to check how the drug affected their health and their baby's health. It helps doctors understand the safety of this treatment for mothers and babies.
Morrisville, North CarolinaAges 16 years+ - NCT06628921Recruiting
Eptinezumab for treating a migraine attack right now
This trial tests if eptinezumab can stop a migraine attack that is already happening. It may help people who get migraines often and are already part of the TACHIS study.
RomaAges 18 years+ - NCT06629116Recruiting
Albumin treatment for large strokes after thrombectomy
This trial tests if giving a protein called albumin after a large stroke can improve recovery. Albumin may help reduce brain swelling and damage. You may qualify if you had a large stroke in the front part of the brain, got a clot-removal procedure, and meet certain age and health criteria.
Zhangzhou, FujianAges 18–80 - NCT06629207Recruiting
AI predicts Parkinson's risk in sleep behavior disorder
This study uses artificial intelligence to analyze brain scans and predict whether people with REM sleep behavior disorder are at risk of developing Parkinson's disease. It aims to find early signs before symptoms appear.
BernAges 18 years+ - NCT06629389RecruitingPhase 2
Cannabidiol (Kanbis) for Parkinson's symptoms
This trial tests whether cannabidiol (CBD) can help with Parkinson's disease symptoms. Researchers want to see if it's safe and effective for people with mild to moderate Parkinson's who are already on stable medications.
Mendoza, Mendoza ProvinceAges 40–80 - NCT06629428RecruitingEarly Phase 1
Study of ublituximab for walking and movement in multiple sclerosis
This trial tests if ublituximab can improve walking and other motor skills in people with active relapsing MS. You must be able to walk at least 25 feet and stand 30 seconds on your own.
Atlanta, GeorgiaAges 18–55 - NCT06630650Recruiting
Study of Congenital Myasthenic Syndrome (CMS) Over Time
This study follows people with congenital myasthenic syndrome (CMS) over time to learn more about how the condition changes and to find better ways to measure symptoms. You will not receive any treatment, but your participation helps researchers understand CMS better.
Bethesda, MarylandAges 6 months–99 years - NCT06630702Recruiting
Spinal cord stimulation for freezing gait in advanced Parkinson's
This trial tests if a small device placed near your spine (spinal cord stimulation) can help improve freezing of gait in people with advanced Parkinson's whose medicines aren't enough. It also aims to reduce leg pain if you have it.
Hsinchu, Hsinchu CityAges 40–85 - NCT06630949Recruiting
Vitamin D3 and creatine for muscle health in older adults
This study tests whether taking a combination of vitamin D3 and creatine can help older adults with mild mobility problems maintain or improve their muscle function. If you have minor trouble with walking, stairs, or getting in/out of a car, this trial may offer a simple way to help keep your muscles strong.
Hamilton, OntarioAges 60 years+ - NCT06631053Recruiting
Exercise program for 30 days of leg muscle disuse
This study looks at how a specific exercise program affects your muscles after a period of not using them (simulated by a leg brace). You'll wear a brace on one leg for 30 days and do certain exercises to see if they help prevent muscle loss.
Lexington, KentuckyAges 35–45 - NCT06631209Recruiting
TMS for Better Sleep in Insomnia
This study tests whether a non-invasive brain stimulation technique called transcranial magnetic stimulation (TMS) can improve sleep in people with moderate to severe insomnia. You would come to the University of Arizona for several sessions, and the treatment is painless and doesn't require surgery.
Tucson, ArizonaAges 18–60 - NCT06631222Recruiting
Can cognitive behavioral therapy help smartphone addiction and tension headaches?
This trial tests if cognitive behavioral therapy (a type of talk therapy that changes unhelpful thoughts and behaviors) can reduce both smartphone addiction and tension-type headaches. It is for people aged 19-34 who have frequent tension headaches and are heavy smartphone users.
Cairo, Cairo GovernorateAges 19–34 - NCT06631534RecruitingPhase 4
Testing dexmedetomidine for kids having heart defect closure
This trial tests adding a sedative medicine called dexmedetomidine to standard anesthesia for children aged 3 to 12 who are having a procedure to close a hole in their heart (atrial septal defect). The goal is to see if it helps them recover more smoothly.
Alexandria, Alexandria GovernorateAges 3–12 - NCT06631742Recruiting
Exergaming for dementia: a fun exercise trial
This trial tests whether playing interactive video games that combine exercise and thinking challenges (called 'exergaming') can help people with dementia. It aims to see if this fun way to move and think can improve memory, daily function, and quality of life.
Wetzikon, Canton of ZurichAges Any age - NCT06631976Recruiting
Non-surgical treatment for partial rotator cuff tear
This trial tests a conservative (non-surgical) approach for people with a small tear in the supraspinatus tendon (a rotator cuff muscle) that is causing shoulder pain and sleep problems. It aims to see if avoiding surgery can help improve symptoms and sleep quality.
Lodz, Łódź VoivodeshipAges 40–75 - NCT06632587Recruiting
Early vs. late skull replacement after brain surgery
This trial compares putting the skull piece back early (around 8 weeks after the initial surgery) versus later (after 8 weeks) in people who had a hemicraniectomy for high brain pressure. The goal is to see which timing leads to better outcomes.
Philadelphia, PennsylvaniaAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,462 recruiting neurology studies from the U.S. registry right now, out of 19,649 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.