Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,487 recruiting studies in this area right now.
By phase
- Not applicable9,830
- Phase 2786
- Phase 1573
- Phase 3532
- Phase 4343
- Phase 1/Phase 2304
- Phase 2/Phase 3119
Top conditions
- Stroke855
- Parkinson Disease423
- Alzheimer Disease341
- Multiple Sclerosis341
- Dementia229
- Ischemic Stroke200
- Epilepsy195
- Obstructive Sleep Apnea155
- Traumatic Brain Injury154
- Insomnia153
- Spinal Cord Injuries151
- Sarcopenia149
- Acute Ischemic Stroke141
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Migraine113
- Pain Management113
- Amyotrophic Lateral Sclerosis107
Leading sponsors
- Beijing Tiantan Hospital135
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University71
- National Taiwan University Hospital69
- University of Minnesota63
Where studies are running
- California673
- Massachusetts306
- New York293
- Florida278
- Texas270
- Maryland245
- Alabama213
- Arizona212
- Illinois193
- Pennsylvania177
Recruiting studies12,485 total
- NCT07218484Recruiting
VoiceLove therapy for confusion after ICU surgery
This trial tests if a digital therapy called VoiceLove can help prevent or treat delirium (sudden confusion) in patients recovering from major surgery in the ICU. It also involves family members and care teams in the therapy.
Houston, TexasAges 18 years+ - NCT07218913RecruitingPhase 1
Testing a drug to reduce ear damage from chemo in testicular cancer
This trial tests whether adding Pedmark (sodium thiosulfate) to cisplatin chemotherapy can protect hearing in men with stage II or III testicular germ cell tumors. It aims to reduce the risk of drug-related ear damage while still treating the cancer.
Duarte, CaliforniaAges 18 years+ - NCT07218991Recruiting
Wearable sound device to help with walking
This study tests a wearable device that uses sound to help people navigate their surroundings. It might be helpful for people who have trouble seeing, but you must be healthy overall.
Galveston, TexasAges 18–100 - NCT07219108Recruiting
Vagus nerve stimulation for recovery in the NeuroICU
This trial tests whether a gentle electrical pulse on the ear can help patients recover from severe brain or spinal cord conditions in the NeuroICU. It may improve healing by activating the vagus nerve.
St Louis, MissouriAges 18 years+ - NCT07219407RecruitingPhase 2
Long-term safety study of RAP-219 for focal seizures
This study tests the long-term safety and effectiveness of RAP-219, an investigative medication for focal epilepsy. It is for people who already completed an earlier study of RAP-219, have a type of epilepsy that doesn't respond to standard medicines, and use a surgically implanted brain device (RNS system) to help manage seizures.
Boise, IdahoAges 18–70 - NCT07219680Recruiting
Communication quality of life in primary progressive aphasia
This trial tests a therapy to improve communication for people with primary progressive aphasia (PPA), a condition that slowly affects language. You and a care partner will attend video sessions to work on communication goals together.
Austin, TexasAges 40 years+ - NCT07219927Recruiting
Patient experiences with pump-delivered Parkinson's drug
This study looks at real-world experiences of people with Parkinson's who are using ONAPGO, a medication given continuously under the skin through a pump. The goal is to understand how this treatment works in daily life.
Aliso Viejo, CaliforniaAges 18 years+ - NCT07220525Recruiting
Sleep and heart rhythm study for people with sleep apnea device
This study looks at how turning off your sleep apnea device for short periods affects your heart rhythm, especially if you have a condition like atrial fibrillation. It may help understand the link between sleep and heart health.
San Francisco, CaliforniaAges 21 years+ - NCT07220603RecruitingPhase 2
Long-term safety study for people with myotonic dystrophy type 1
This is a follow-up study for people with myotonic dystrophy type 1 who already received the study drug PGN-EDODM1 in an earlier trial. It lets you continue treatment and helps researchers learn more about long-term safety and effects.
Calgary, AlbertaAges Any age - NCT07220694Recruiting
Sabroxy supplement for memory and insulin resistance
This study tests whether a supplement called Sabroxy can improve insulin resistance and memory in adults with mild cognitive impairment and insulin resistance. It may help if you have early memory problems and your blood sugar is slightly higher than normal.
San Francisco, CaliforniaAges 40–80 - NCT07220746Recruiting
Math learning study for first graders
This study looks at how math skills and thinking skills affect each other in first graders with math learning difficulties. If your child is in a participating school and scores below certain levels on math and memory tests, they may be able to join.
Nashville, TennesseeAges 6–8 - NCT07221240RecruitingPhase 1
Amisodin safety study for healthy adults with ALS
This trial tests a new drug called Amisodin in healthy adults who also have ALS. It checks if the drug is safe and how the body processes it.
Baltimore, MarylandAges 18–55 - NCT07221266Recruiting
Exercise programs for people with Parkinson’s
This study tests how different exercise programs affect movement, fitness, and quality of life in people with Parkinson’s disease. It may help you find an exercise routine that improves your symptoms.
El Paso, TexasAges 50 years+ - NCT07221318Recruiting
Studying a vibration mat for better sleep and recovery
This study tests if using a special mat that gently vibrates can help healthy adults sleep better and recover from daily stress. Participants will use the mat for short sessions at home over 3 weeks and visit the lab twice for check-ins.
Miami, FloridaAges 18–45 - NCT07221331Recruiting
Neurofibromatosis type 1 study in Egypt
This study looks at how neurofibromatosis type 1 (NF1) affects people in Egypt, including how it progresses and how it is managed. Researchers will review medical records of patients diagnosed with NF1 between 2010 and 2023 to learn more about the condition.
Al MansurahAges Any age - NCT07221344RecruitingPhase 1/Phase 2
Study of an experimental drug for early Alzheimer's disease
This study tests an investigational drug, ARO-MAPT-SC, which targets a protein involved in Alzheimer's disease. It is for people with early Alzheimer's to see if the drug is safe and can slow the disease.
East York, OntarioAges 18–80 - NCT07221786Recruiting
Opioid reduction before spine surgery
This trial tests whether slowly reducing opioid pain medications before spine surgery can lead to a better recovery afterward. It is for adults already taking daily opioids who have major spine surgery planned at least a month away.
Philadephia, PennsylvaniaAges 18 years+ - NCT07221838RecruitingPhase 4
Steroid Tapering Study for Myasthenia Gravis on Ravulizumab
This study is for people with generalized myasthenia gravis who are already on ravulizumab and a daily steroid. It aims to see if the steroid dose can be safely lowered over time.
Chicago, IllinoisAges 18 years+ - NCT07222033Recruiting
Self-balancing exoskeleton for spinal cord injury
This trial will test a self-balancing personal exoskeleton for people with spinal cord injuries. It may help you walk again and improve your mobility.
New York, New YorkAges 18 years+ - NCT07222202Recruiting
Testing flexible hearing aids for hearing loss
This study tests flexible hearing aids for people with conductive or mixed hearing loss (where sound is blocked or not transmitted well to the inner ear). It aims to see if these devices work well and are comfortable for daily use.
Winston-Salem, North CarolinaAges 6 months–80 years - NCT07222280Recruiting
Alzheimer's dementia and brain inflammation trial
This trial tests if treating brain inflammation can help older adults hospitalized with sudden confusion or cognitive issues. It may help those without a prior dementia diagnosis but who have toxic or metabolic causes for their symptoms.
Crossville, TennesseeAges 60–90 - NCT07222618Recruiting
Selfie videos to measure function in MS
This trial asks people with MS to record short 'selfie' videos of themselves doing everyday tasks, like walking or getting dressed. The goal is to find a better, more personal way to measure how MS affects daily function.
San Francisco, CaliforniaAges 18 years+ - NCT07223008Recruiting
Bilateral artery embolization for chronic migraine
This trial tests a procedure called bilateral middle meningeal artery embolization to see if it reduces chronic migraine symptoms in people who haven't found relief from other treatments. It's for those with frequent, disabling migraines that affect both sides of the head.
Baltimore, MarylandAges 18–80 - NCT07223086Recruiting
Tinted contact lenses for concussion light sensitivity
This trial tests if special tinted contact lenses can help reduce light sensitivity caused by a concussion. It may help people who have had a mild concussion in the past two years and are bothered by light.
Birmingham, AlabamaAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,487 recruiting neurology studies from the U.S. registry right now, out of 19,851 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.