Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,487 recruiting studies in this area right now.
By phase
- Not applicable9,830
- Phase 2786
- Phase 1573
- Phase 3532
- Phase 4343
- Phase 1/Phase 2304
- Phase 2/Phase 3119
Top conditions
- Stroke855
- Parkinson Disease423
- Alzheimer Disease341
- Multiple Sclerosis341
- Dementia229
- Ischemic Stroke200
- Epilepsy195
- Obstructive Sleep Apnea155
- Traumatic Brain Injury154
- Insomnia153
- Spinal Cord Injuries151
- Sarcopenia149
- Acute Ischemic Stroke141
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Migraine113
- Pain Management113
- Amyotrophic Lateral Sclerosis107
Leading sponsors
- Beijing Tiantan Hospital135
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University71
- National Taiwan University Hospital69
- University of Minnesota63
Where studies are running
- California673
- Massachusetts306
- New York293
- Florida278
- Texas270
- Maryland245
- Alabama213
- Arizona212
- Illinois193
- Pennsylvania177
Recruiting studies12,485 total
- NCT07211828Recruiting
Brain activity and pain signals during anesthesia study
This study looks at how opioids and sedatives affect brain activity and pain signals in patients getting anesthesia for an ERCP procedure.
MiaoliAges 18 years+ - NCT07212075Recruiting
Digital twin study for mental health in diabetes
This study uses digital twins—a virtual model of your health—to track how your mental health changes with diabetes. It aims to find patterns that could help personalize mental health care.
Bad Mergentheim, Baden-WurttembergAges 18–80 - NCT07212114RecruitingPhase 3
Comparing two numbing medicines for ankle replacement
This study compares two numbing medicines given during ankle replacement surgery to see which one works better for controlling pain after the operation. It may help you have less pain and need fewer pain pills afterward.
Atlanta, GeorgiaAges 18 years+ - NCT07212244Recruiting
Focused ultrasound for hard-to-treat tremor
This study uses a focused ultrasound treatment guided by MRI to calm hand tremors in people with essential tremor that hasn't responded to medication. It aims to improve daily life by reducing shaking without the need for surgery.
Toronto, OntarioAges 22 years+ - NCT07212699Recruiting
Knee osteoarthritis app-based outcome score study
This trial uses a smartphone app to track symptoms in people with knee osteoarthritis or a knee replacement. The goal is to develop a better way to measure how patients are doing.
Munich, BavariaAges 18 years+ - NCT07212829Recruiting
Brain stimulation during exercise for chronic pain
This trial tests whether adding gentle brain stimulation (tDCS) to exercise can help people with chronic widespread pain (like fibromyalgia). It aims to see if this combination reduces pain better than exercise alone.
JetteAges 18–70 - NCT07212894Recruiting
Dementia app for caregivers in Malaysia
This study tests a mobile app called DemensiaKITA to help dementia caregivers learn more, feel more confident, and reduce stress. If you take care of a family member with dementia, you may be able to join.
Sungai Buloh, SelangorAges 18 years+ - NCT07213063Recruiting
Creatine and HMB supplements for Down syndrome
This trial tests whether taking creatine and HMB supplements can improve muscle strength, reduce inflammation, and increase muscle mass in people with Down syndrome. It may help if you or your loved one can do basic physical tests like standing from a chair and do not have kidney disease or severe mobility issues.
Burgos, BurgosAges 18 years+ - NCT07213349RecruitingPhase 2
Daridorexant for Alzheimer's prevention
This study tests whether daridorexant, a medication that helps improve sleep, can prevent Alzheimer's disease. If you have mild memory concerns but not dementia, this trial may help find out if better sleep can protect your brain.
Montreal, QuebecAges 50–90 - NCT07213856Recruiting
Dietary help for constipation in Parkinson's disease
This study tests whether a special diet can help improve constipation symptoms in people with early-stage Parkinson's disease. It aims to see if changing what you eat can make bowel movements more regular and comfortable.
Porto Alegre, Rio Grande do SulAges 18 years+ - NCT07213986Recruiting
Vibrant capsule for bowel problems after spinal cord injury
This trial tests a vibrating capsule to help people with spinal cord injury have more regular bowel movements. It might be an option if you have had a spinal cord injury for at least one year and follow a steady bowel program.
Houston, TexasAges 21 years+ - NCT07214415RecruitingPhase 2
Hyperbaric oxygen therapy for veterans with brain injury or mental health issues
This trial tests whether hyperbaric oxygen therapy (breathing pure oxygen in a pressurized chamber) can improve thinking, mood, and quality of life in veterans with mild traumatic brain injury, PTSD, anxiety, or depression. You must have already tried at least one evidence-based therapy like CBT or EMDR.
Boise, IdahoAges 18–75 - NCT07214480Recruiting
Speech therapy for children who struggle with the /s/ sound
This study tests a treatment program for children aged 7 to 11 who have trouble saying the /s/ sound. It's done over Zoom with a computer, and researchers will check if the therapy helps improve their speech.
Syracuse, New YorkAges 7–11 - NCT07214727RecruitingPhase 1
A study of ALN-5288 for Alzheimer's disease
This trial tests an investigational drug called ALN-5288 for people with Alzheimer's disease. It aims to see if the drug is safe and how it affects the body.
MontrealAges 40–80 - NCT07215416RecruitingPhase 1/Phase 2
Gene therapy for ataxia-telangiectasia with specific ATM mutation
This trial tests a new genetic medicine designed for people with A-T who have a specific ATM gene change. It aims to see if the treatment is safe and if it can improve symptoms.
Boston, MassachusettsAges birth–17 years - NCT07215715Recruiting
Heart ultrasound study for older adults with heart failure
This study uses a special ultrasound to measure heart stiffness in people 60 and older who have heart failure with preserved or mildly reduced pumping function, with or without a condition called ATTR amyloidosis (a protein buildup in the heart). It also includes healthy controls.
Boston, MassachusettsAges 60 years+ - NCT07216066RecruitingPhase 1
Study of ALN-SNCA for early Parkinson's disease
This trial tests a new experimental drug called ALN-SNCA, given as an injection into the spinal fluid, for people with early Parkinson's disease. The goal is to see if it is safe and well-tolerated.
Montreal, QuebecAges 50–80 - NCT07216157Recruiting
Sealant vs no sealant for skull base surgery
This trial tests whether using a sealant after skull base surgery helps prevent spinal fluid leaks. It compares patients who get a sealant with those who don't.
WarsawAges 18 years+ - NCT07216261Recruiting
The SWELL study: CBT for insomnia in older veterans
This trial tests whether providing cognitive behavioral therapy for insomnia (CBTI) can help older veterans in VA clinics. CBTI is a non-medication treatment that addresses the thoughts and behaviors that keep you awake.
Durham, North CarolinaAges 60 years+ - NCT07217054Recruiting
Parkinson's and RBD diagnosis via colon biopsy
This trial uses a small piece of colon tissue, taken during a routine colonoscopy, to look for a protein linked to Parkinson's disease and REM sleep behavior disorder (RBD). It aims to improve diagnosis for these conditions.
Branford, ConnecticutAges 40–99 - NCT07217769Recruiting
Naps for night shift workers' heart health and performance
This study tests whether taking short planned naps during night shifts can help lower blood pressure and improve how well you feel and perform at work. It is for public safety or healthcare workers in Western Pennsylvania who currently work nights.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT07217912RecruitingPhase 2
Study of daridorexant to prevent confusion after heart surgery
This trial tests whether a sleep medication called daridorexant can help prevent delirium (sudden confusion) in older adults after heart surgery. You must be 60 or older and having a specific type of heart operation.
Rochester, New YorkAges 60 years+ - NCT07218081RecruitingPhase 1
Intermittent deep brain stimulation for early Alzheimer's
This trial tests a treatment that sends gentle electrical pulses to a part of the brain involved in memory and thinking. It is for people with early-stage Alzheimer's who live at home and have a caregiver who can help.
Augusta, GeorgiaAges 65–85 - NCT07218276Recruiting
Passive robot study for stroke recovery
This study tests a passive robot (a device that moves without force) to help stroke survivors regain arm movement. It aims to see if this approach is safe and helpful for people with arm weakness after a stroke.
Ann Arbor, MichiganAges 18–75
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,487 recruiting neurology studies from the U.S. registry right now, out of 19,851 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.