Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,487 recruiting studies in this area right now.
By phase
- Not applicable9,830
- Phase 2786
- Phase 1573
- Phase 3532
- Phase 4343
- Phase 1/Phase 2304
- Phase 2/Phase 3119
Top conditions
- Stroke855
- Parkinson Disease423
- Alzheimer Disease341
- Multiple Sclerosis341
- Dementia229
- Ischemic Stroke200
- Epilepsy195
- Obstructive Sleep Apnea155
- Traumatic Brain Injury154
- Insomnia153
- Spinal Cord Injuries151
- Sarcopenia149
- Acute Ischemic Stroke141
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Migraine113
- Pain Management113
- Amyotrophic Lateral Sclerosis107
Leading sponsors
- Beijing Tiantan Hospital135
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University71
- National Taiwan University Hospital69
- University of Minnesota63
Where studies are running
- California673
- Massachusetts306
- New York293
- Florida278
- Texas270
- Maryland245
- Alabama213
- Arizona212
- Illinois193
- Pennsylvania177
Recruiting studies12,485 total
- NCT07223489Recruiting
Understanding Adult SMA Diagnosis & Treatment Experiences
This trial explores the experiences of adults with spinal muscular atrophy (SMA) in the MedStar Health System, looking at how they are diagnosed and treated, and any differences in care they may face.
Washinton, District of ColumbiaAges 18 years+ - NCT07223827Recruiting
Testing a handheld nerve-signal device
This study is testing a small, handheld device that checks nerve signals at the bedside or in the clinic. It may help doctors quickly understand nerve problems without a big machine.
Indianapolis, IndianaAges 18 years+ - NCT07223944RecruitingPhase 3
Gene therapy trial for Gaucher disease type 1
This trial tests a gene therapy called FLT201 for adults with Gaucher disease type 1. It aims to provide a long-term treatment option for people who have been stable on enzyme replacement therapy (ERT) or substrate reduction therapy (SRT) for at least two years.
Los Angeles, CaliforniaAges 18 years+ - NCT07224256Recruiting
Brain implant trial to help with communication after injury or disease
This trial tests a brain-computer interface (BCI) that is implanted by a robot. It is designed to help people who have lost the ability to speak clearly or use their hands well, due to conditions like ALS, stroke, or spinal cord injury.
Dallas, TexasAges 22–75 - NCT07224178Recruiting
Heart strain and stroke of unknown cause
This study looks at how well the left side of the heart pumps (called strain) in people who had a stroke without a known cause. It aims to see if this heart measurement can help predict future strokes or heart rhythm problems like atrial fibrillation.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT07224243Recruiting
How oxygen during surgery affects recovery
This study looks at how different oxygen levels during surgery affect recovery. It includes adults having surgery with a breathing tube, but excludes people having open-heart surgery, certain lung procedures, or who have had bleomycin chemotherapy.
Ann Arbor, MichiganAges 18 years+ - NCT07224451Recruiting
Liquid biopsy during spine surgery with blood-brain barrier disruption
This trial tests a technique called 'barrier disrupting fields' during spine surgery to temporarily open the blood-brain barrier. This may allow doctors to collect a liquid biopsy (a blood test that looks for tumor DNA) to better understand spinal tumors.
Ramat GanAges 18 years+ - NCT07224503Recruiting
Comparing two programs to help brain tumor patients with thinking skills
This study tests two programs—C-SMART and BE Well—to see which one better helps brain tumor patients who struggle with memory, attention, or other thinking skills. You and your caregiver will participate together in this telehealth-based program.
Richmond, VirginiaAges 18 years+ - NCT07224607Recruiting
Light therapy for early Alzheimer's disease
This study tests a type of light therapy (called transcranial photobiomodulation) to see if it can help people with early-stage Alzheimer's. It involves coming to Cedars-Sinai for weekly sessions over a period of time.
Los Angeles, CaliforniaAges 55–89 - NCT07225101RecruitingPhase 4
Testing STRATAFIX stitches for brain and spine surgery
This trial tests a special type of stitch (called STRATAFIX) for closing wounds after brain or spine surgery. It may help the wound heal better and reduce complications.
Lansing, MichiganAges 18 years+ - NCT07225361RecruitingPhase 4
Ublituximab for early relapsing multiple sclerosis
This study tests ublituximab (Briumvi), a treatment given as an infusion, for people recently diagnosed with relapsing MS. The goal is to see if starting this treatment early helps control MS better.
Chicago, IllinoisAges 18–70 - NCT07225582Recruiting
Best sensory feedback for hand function after spinal injury
This study is for people who have already received the ReHAB system in a previous trial. It aims to find the best ways to use sensory feedback from the device to help with hand and arm function after tetraplegia.
Cleveland, OhioAges 22–65 - NCT07225868Recruiting
Coaching to boost cognitive rehab in MS
This trial tests if coaching in goal-directed behavior can improve cognitive rehabilitation for people with relapsing-remitting or secondary progressive MS. It aims to help patients better manage daily tasks and thinking challenges.
Buffalo, New YorkAges 18–65 - NCT07226167Recruiting
Hearing aid benefit in noisy places
This study tests how well hearing aids help people hear in real-world noisy environments. If you already use hearing aids and have hearing loss in both ears that started after childhood, this trial may help understand how to improve your experience.
Madison, WisconsinAges 18 years+ - NCT07226284Recruiting
Testing a nerve stimulation device for leg movement in Parkinson's
This study tests if a device that stimulates the vagus nerve (a nerve in your neck) can improve leg muscle activity and walking balance in people with Parkinson's disease. You would participate in experiments while wearing the device to see how it affects your movement.
Minneapolis, MinnesotaAges 21–76 - NCT07226674Recruiting
Study of gut health and plant nutrients for brain health
This trial tests whether a natural plant compound can help support memory and thinking in people at higher risk for Alzheimer's disease. You may qualify if you are over 50, overweight, eat a typical Western diet, and have a family history of Alzheimer's.
ColeraineAges 50 years+ - NCT07226700RecruitingPhase 3
Suzetrigine for pain after hip replacement surgery
This study tests an investigational pain medicine called suzetrigine to see how well it controls pain after total hip replacement surgery. It is for adults 18–80 who are having a first-time hip replacement and can receive spinal anesthesia.
New York, New YorkAges 18–80 - NCT07226726RecruitingPhase 1
Stem cell exosome treatment for congenital myasthenic syndrome
This trial tests a treatment made from stem cell exosomes (tiny particles that may help repair cells) for people with congenital myasthenic syndrome, a muscle-weakening condition. It aims to see if this treatment is safe and could improve symptoms.
Naples, FloridaAges 18 years+ - NCT07227246RecruitingPhase 3
Testing rFVIIa for bleeding stroke within 2 hours
This trial tests whether a drug called Recombinant Factor VIIa (rFVIIa) can safely help stop bleeding in the brain during a hemorrhagic stroke. The goal is to give the drug as quickly as possible, within 2 hours of stroke onset, to see if it improves outcomes.
Birmingham, AlabamaAges 18–80 - NCT07227441Recruiting
Chronic Infections and Inflammation in ME/CFS
This study looks at how chronic infections and inflammation affect people with ME/CFS (myalgic encephalomyelitis/chronic fatigue syndrome) compared to healthy people. Researchers want to understand what causes symptoms and find better ways to help.
San Francisco, CaliforniaAges 18 years+ - NCT07227610RecruitingPhase 2
Focused Radiation for Large Brain Tumors (BIGSHOT)
This trial tests a new way of giving focused radiation (SRS) to larger brain tumors (2 to 5 cm). It aims to safely treat these big tumors without whole-brain radiation, which can have more side effects.
Charleston, South CarolinaAges 18 years+ - NCT07227740Recruiting
Testosterone treatment for blood vessel health after spinal cord injury
This study looks at whether low testosterone affects blood vessel health in men with recent spinal cord injury. It tests if testosterone replacement can help improve blood vessel function.
Englewood, ColoradoAges 18–89 - NCT07227727Recruiting
Blood vessel health after spinal cord injury
This study looks at how spinal cord injury affects the health of your blood vessels. It compares people with paraplegia to those without an injury to understand the differences.
Englewood, ColoradoAges 18 years+ - NCT07227961Recruiting
Sarcoma surgery and recovery study using a phone app
This study uses a phone app to track how well people recover after surgery for bone or soft tissue sarcoma. It may help doctors understand how to improve movement and quality of life after treatment.
Phoenix, ArizonaAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,487 recruiting neurology studies from the U.S. registry right now, out of 19,851 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.