Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,487 recruiting studies in this area right now.
By phase
- Not applicable9,830
- Phase 2786
- Phase 1573
- Phase 3532
- Phase 4343
- Phase 1/Phase 2304
- Phase 2/Phase 3119
Top conditions
- Stroke855
- Parkinson Disease423
- Alzheimer Disease341
- Multiple Sclerosis341
- Dementia229
- Ischemic Stroke200
- Epilepsy195
- Obstructive Sleep Apnea155
- Traumatic Brain Injury154
- Insomnia153
- Spinal Cord Injuries151
- Sarcopenia149
- Acute Ischemic Stroke141
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Migraine113
- Pain Management113
- Amyotrophic Lateral Sclerosis107
Leading sponsors
- Beijing Tiantan Hospital135
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University71
- National Taiwan University Hospital69
- University of Minnesota63
Where studies are running
- California673
- Massachusetts306
- New York293
- Florida278
- Texas270
- Maryland245
- Alabama213
- Arizona212
- Illinois193
- Pennsylvania177
Recruiting studies12,485 total
- NCT07237542Recruiting
Remote ischemic preconditioning for small stroke prevention
This study tests whether a simple, non-invasive treatment called remote ischemic preconditioning (using brief periods of blood pressure cuff inflation on the arm) can help prevent early neurological worsening in people who have had a small, specific type of stroke. It may offer a safe way to protect your brain while you recover.
Nanjing, JiangsuAges 18 years+ - NCT07238465RecruitingPhase 3
Exploring nervous system function in Down syndrome
This trial studies how the nervous system works in people with Down syndrome. It may help understand differences in body functions and improve future care.
Aurora, ColoradoAges 18–50 - NCT07238868RecruitingPhase 2
Long-term safety study of CB03-154 for epilepsy
This study is a long-term follow-up for people with epilepsy who already completed a previous trial of the drug CB03-154. It checks if the drug remains safe and effective over more time.
Melbourne, VictoriaAges 18–70 - NCT07239427Recruiting
Brain stimulation with pain coping for fibromyalgia
This study tests whether a gentle electrical brain stimulation method (tDCS), combined with a pain coping program, can help reduce fibromyalgia pain. It compares two groups to see if adding brain stimulation makes the coping program more effective.
Valladolid, ValladolidAges 18 years+ - NCT07239817Recruiting
Nerve block plus numbing medicine for hip fracture surgery
This study tests a special nerve block (PENG block) combined with a numbing medicine injection around the hip joint to provide better pain relief after hip replacement surgery for a broken hip. It aims to see if this approach can reduce pain and the need for strong pain medicines.
MilanAges 18 years+ - NCT07239869RecruitingPhase 1
Robot-assisted activity program for dementia and caregivers
This trial tests a robot-assisted activity program designed to help people with mild-to-moderate dementia and their caregivers become more physically active. It aims to improve health and well-being for both.
Hong KongAges 18 years+ - NCT07240337Recruiting
Botox injections for arm and leg spasticity after stroke
This study looks at how well botulinum toxin (Botox) works for reducing muscle tightness in people who have weakness on one side of the body after a stroke. It will use medical records from before and after treatment to see if the injections improve function.
Istanbul, BahcelievlerAges 18–75 - NCT07240454Recruiting
Should you keep taking aspirin for a chronic brain bleed?
This trial looks at whether people with a chronic subdural hematoma (a slow bleed on the brain) who are not having surgery should keep taking aspirin or stop it. It aims to find out which approach is safer and helps the hematoma heal better.
BeijingAges 18 years+ - NCT07240844RecruitingPhase 4
Enavogliflozin for amyloid heart disease
This study tests a drug called enavogliflozin to see if it helps people with a specific type of heart failure caused by amyloid buildup. It may improve symptoms and daily function.
SeoulAges 19 years+ - NCT07240896RecruitingEarly Phase 1
Testing a new mRNA therapy for Wilson disease
This trial tests an experimental mRNA treatment (DSL101) for adults with Wilson disease. It's for people whose condition is stable on current therapy and who have certain genetic markers. The goal is to see if the new treatment can help the body process copper better and reduce the need for standard medicines.
Hefei, AnhuiAges 18 years+ - NCT07241234RecruitingPhase 1
Study of an experimental drug for phenylketonuria (PKU)
This trial tests an investigational drug (AG-181) for people with PKU who have a specific genetic change (R408W mutation). It aims to check if the drug is safe and how it works in your body.
Indianapolis, IndianaAges 18–69 - NCT07241429Recruiting
Fear of movement and balance after stroke
This study looks at how fear of movement (kinesiophobia) affects balance in people who have had a stroke. It may help understand how to improve recovery.
IstanbulAges 18–80 - NCT07241520RecruitingPhase 3
Testing SHPL-49 injection for recent stroke patients
This trial tests a new medication, SHPL-49, given as an injection to people who have just had a stroke caused by a blood clot (ischemic stroke). It is for patients who are already receiving standard clot-busting treatment within 8 hours of symptoms starting. The study will see if adding this drug helps improve recovery.
Linfen, ShanxiAges 18–80 - NCT07242573Recruiting
Exercise and brain stimulation for fibromyalgia
This study tests if combining physical exercise with a gentle brain stimulation technique can improve pain, sleep, and fatigue in people with fibromyalgia.
Warsaw, Masovian VoivodeshipAges 20–80 - NCT07242638RecruitingPhase 2
Abrocitinib for skin and hair loss in Down syndrome
This study tests if the pill abrocitinib can help people with Down syndrome who have atopic dermatitis (eczema) or alopecia areata (patchy hair loss). The goal is to see if it improves their skin or hair with manageable side effects.
New York, New YorkAges 12 years+ - NCT07242768Recruiting
Long-term exercise follow-up for artery narrowing
This trial looks at the long-term effects of regular exercise for people with narrowed brain arteries. It follows participants from a previous study to see if exercise continues to help over three more years.
BeijingAges 40–80 - NCT07242833Recruiting
Does season affect biological age? A study in adults.
This study looks at how the changing seasons might affect your biological age—a measure of how well your body is aging. If you are over 40 and generally healthy, you may help us understand how factors like time of year influence aging.
Lausanne, CHAges 40 years+ - NCT07243405Recruiting
Nerve stimulation for sleep breathing problems
This trial tests a nerve stimulation device for people with moderate to severe sleep-disordered breathing who cannot use or tolerate standard treatments. It may help you breathe better during sleep.
Panama City, Provincia de PanamáAges 18 years+ - NCT07243470RecruitingPhase 1/Phase 2
Tarlatamab and temozolomide for brain tumors
This trial tests a new combination of two drugs (tarlatamab and temozolomide) for people with certain types of aggressive brain or central nervous system tumors that have come back or not responded to standard treatment. The hope is that this combination may work better against tumors that have a specific marker called DLL3.
AngersAges 12 years+ - NCT07244029Recruiting
Herbal extract for pain and swelling after wisdom tooth surgery
This trial tests if an herbal extract called Reparil (aescin) can reduce pain, swelling, and stiffness after impacted wisdom tooth removal. It compares Reparil to a standard pain reliever (ibuprofen) to see which works better for recovery.
Muscat, Al KhoudAges 18–40 - NCT07244133Recruiting
Powerball exercise for kids with Down syndrome
This trial tests whether using a Powerball (a small exercise ball) can improve hand strength and coordination in children with Down syndrome. It may help with daily tasks and motor skills.
Lahore, Punjab ProvinceAges 6–10 - NCT07244146Recruiting
Hand therapy for children with spastic cerebral palsy
This trial tests a therapy called CHRIST for children ages 6-12 who have spastic cerebral palsy affecting one side. The goal is to improve hand use and arm function.
Lahore, Punjab ProvinceAges 6–12 - NCT07244159Recruiting
Dynamic surface exercise for children with cerebral palsy
This study tests whether exercising on an unstable surface (like a foam mat or ball) can improve balance and movement in children with diplegic cerebral palsy. It may help kids who use a walker or wheelchair have better control and independence.
Lahore, Punjab ProvinceAges 5–8 - NCT07244328RecruitingEarly Phase 1
UX-GIP001 cell therapy for drug-resistant temporal lobe epilepsy
This trial tests a new cell therapy, UX-GIP001, for people whose seizures start in one small area of the brain (the mesial temporal lobe) and are not controlled by at least two seizure medications. The goal is to see if this treatment can safely reduce seizures.
Hangzhou, ZhejiangAges 18–75
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,487 recruiting neurology studies from the U.S. registry right now, out of 19,851 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.