Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,497 recruiting studies in this area right now.
By phase
- Not applicable9,839
- Phase 2787
- Phase 1573
- Phase 3531
- Phase 4344
- Phase 1/Phase 2304
- Phase 2/Phase 3119
Top conditions
- Stroke856
- Parkinson Disease424
- Alzheimer Disease341
- Multiple Sclerosis341
- Dementia228
- Ischemic Stroke201
- Epilepsy196
- Insomnia156
- Obstructive Sleep Apnea155
- Traumatic Brain Injury154
- Spinal Cord Injuries151
- Sarcopenia149
- Acute Ischemic Stroke141
- Cerebral Palsy129
- Mild Cognitive Impairment128
- Migraine113
- Pain Management113
- Amyotrophic Lateral Sclerosis107
Leading sponsors
- Beijing Tiantan Hospital135
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic98
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University71
- National Taiwan University Hospital69
- University of Minnesota63
Where studies are running
- California675
- Massachusetts305
- New York294
- Florida277
- Texas270
- Maryland245
- Alabama213
- Arizona211
- Illinois193
- Pennsylvania177
Recruiting studies12,495 total
- NCT00313677Recruiting
Trial readiness for dystroglycan-related muscle conditions
This trial is for people who have signs that they may have a dystroglycanopathy—a group of muscle conditions. It helps study how ready participants are for care and possibly future treatments by using lab and genetic/pathology information to confirm the condition.
Iowa City, IowaAges Any age - NCT00585572Enrolling by invitation
Wisconsin Brain Donor Program for research after death
This program collects donated brain tissue and related samples after death to help researchers study brain diseases. You may be eligible if you’re an approved family member of a specific study participant, or you meet certain health and consent requirements.
Madison, WisconsinAges 18 years+ - NCT00102544Enrolling by invitation
Tracking Devices to Find Abnormalities During Medical Procedures
This study tests technology that uses imaging scans to help doctors locate and reach abnormalities during surgical or interventional procedures. The goal is to make these image-guided procedures more accurate and safer for patients.
Bethesda, MarylandAges 18–120 - NCT00795080Enrolling by invitation
Neck MRI study of fluid flow in spine and skull problems
This study uses special MRI scans to measure how fluid moves around the brain and spinal cord. It may help researchers better understand craniovertebral junction (CVJ) and Chiari I malformations by comparing fluid-flow patterns during neck movement.
Ages 12 years+ - NCT01195558Recruiting
Registry survey for people who are blind and have sleep problems
This study is a registry survey that collects information about sleep problems and daytime sleepiness. It may help researchers better understand sleep issues in people who are blind and plan future studies or treatments.
Washington D.C., District of ColumbiaAges Any age - NCT01453127Enrolling by invitationPhase 4
DaTscan scan for aging and movement brain conditions
This trial uses a special brain scan called DaTscan to study how certain brain conditions change with aging and over time. It may help researchers better understand movement and other neurodegenerative conditions and who may benefit from future treatments.
Rochester, MinnesotaAges 40–90 - NCT00593203Enrolling by invitation
Share a brain tissue sample during surgery
This study collects a small piece of brain tissue during people’s planned brain surgery. It may help researchers learn more about brain conditions and improve future care.
Nashville, TennesseeAges Any age - NCT07397923RecruitingPhase 2
Zenicom digital therapy for post-stroke aphasia
This study tests a digital therapy app called Zenicom that may help improve language problems after a stroke. It is for people who had a first stroke in the last 3 months and now have trouble speaking or understanding language.
Seongnam-siAges 19 years+ - NCT07398157Recruiting
24-hour adaptive deep brain stimulation for Parkinson's
This trial tests a new deep brain stimulation system that adapts in real time to improve symptom control over 24 hours, especially for people with daytime fluctuations or sleep problems despite standard DBS.
San Francisco, CaliforniaAges 18 years+ - NCT07398183Recruiting
Sleep help for kids with autism
This study tests a sleep program for children with autism who have trouble falling asleep. It aims to improve sleep for both the child and parents.
Hong KongAges 6–12 - NCT07398495Recruiting
Exercise program for diabetes and muscle loss
This study tests whether a special exercise program can help middle-aged and older adults who have both type 2 diabetes and muscle loss. It aims to improve muscle strength, balance, and overall health.
Taichung, TaiwanAges 45–85 - NCT07398599Recruiting
Double-dose targeted therapy plus chemo for lung cancer spread to brain lining
This trial tests a stronger dose of an EGFR-targeted drug combined with bevacizumab and chemotherapy into the spinal fluid for patients with non-small cell lung cancer that has spread to the lining of the brain and is no longer responding to standard treatment.
Nanchang, JiangxiAges 18–99 - NCT07399262Recruiting
Music-based walking training for multiple sclerosis
This study tests whether walking to a steady beat of music can help improve your walking and balance. It is for people with mild to moderate multiple sclerosis who can walk but may need a little support.
Istanbul, ZeytinburnuAges 18–65 - NCT07399327Recruiting
SEEG thermocoagulation for hard-to-treat epilepsy
This study is looking at how well a procedure called SEEG thermocoagulation (a way to stop seizures by heating a small area of brain tissue) works for people with epilepsy that doesn't improve with medication. By joining, you will help doctors understand why this treatment works for some people and not others.
MarseilleAges 12 years+ - NCT07399418Recruiting
Tracking risk in integrated Alzheimer's diagnosis
This study is looking for people with or at risk for Alzheimer's disease and their caregivers. It aims to track risk factors and improve diagnosis using a combination of tests and tools.
Montescano, Pavia, ItalyAges 50 years+ - NCT07399704RecruitingPhase 2
Testing a new drug for two rare brain diseases
This trial is for people with Niemann-Pick type C or GM2 gangliosidosis who are already on or have been in a related study. It tests a new drug called Nizubaglustat to see if it is safe and works better than current treatments.
Água Verde, CuritibaAges 12 years+ - NCT07399964Recruiting
Sleep treatment study for young people with insomnia
This study tests whether a type of talk therapy for insomnia (CBT-I) can help reduce impulsivity and risk-taking in Chinese youth who have trouble sleeping. If you are aged 12 to 24 and have insomnia, you may be able to join.
Hong KongAges 12–24 - NCT07400198Recruiting
Walking and Bone Health Study for SMA
This study looks at walking and bone health in people with spinal muscular atrophy (SMA). It helps researchers understand how SMA affects your gait (the way you walk) and your bones, which could lead to better treatments.
New York, New YorkAges 8–50 - NCT07400640Recruiting
Comparing two treatments for postherpetic neuralgia pain
This trial compares two procedures—a nerve block injection and a radiofrequency treatment—to see which works better for lasting pain after shingles. It aims to help people with persistent pain in the neck, chest, or lower back.
AnkaraAges 18–80 - NCT07400939Recruiting
Brain stimulation and hand movement training for stroke recovery
This trial tests if combining brain stimulation with watching hand movements can improve hand function in people who had a stroke 6 to 24 months ago. It may help you regain better use of your affected hand.
Kota Kinabalu, SabahAges 18–59 - NCT07400731Recruiting
Ear stimulation for Parkinson's symptoms
This study tests whether a device that stimulates the ear can improve Parkinson's symptoms during 'off' periods, when medication wears off. It compares how you feel before and after ear stimulation.
IstanbulAges 44 years+ - NCT07400848Recruiting
Symptoms and recovery after COVID-19 vaccine
This study looks at people who developed new, long-lasting symptoms after a COVID-19 vaccine. It aims to understand their symptoms, do lab tests, and see how they recover over time.
BernAges 18 years+ - NCT07401121RecruitingPhase 1
Study of CTx1000 for people with ALS
This trial tests a new drug, CTx1000, for people with ALS. It aims to see if the drug is safe and tolerable, and may offer a new treatment option.
Sydney, New South WalesAges 18–80 - NCT07401147Recruiting
TENS for pain relief during first labor
This trial tests a gentle electrical device (TENS) to help manage pain during labor. It's for women having their first baby, with a healthy, single pregnancy, and no major health issues.
Tegucigalpa, Francisco Morazán DepartmentAges 18–45
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,497 recruiting neurology studies from the U.S. registry right now, out of 19,911 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.