Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,497 recruiting studies in this area right now.
By phase
- Not applicable9,839
- Phase 2787
- Phase 1573
- Phase 3531
- Phase 4344
- Phase 1/Phase 2304
- Phase 2/Phase 3119
Top conditions
- Stroke856
- Parkinson Disease424
- Alzheimer Disease341
- Multiple Sclerosis341
- Dementia228
- Ischemic Stroke201
- Epilepsy196
- Insomnia156
- Obstructive Sleep Apnea155
- Traumatic Brain Injury154
- Spinal Cord Injuries151
- Sarcopenia149
- Acute Ischemic Stroke141
- Cerebral Palsy129
- Mild Cognitive Impairment128
- Migraine113
- Pain Management113
- Amyotrophic Lateral Sclerosis107
Leading sponsors
- Beijing Tiantan Hospital135
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic98
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University71
- National Taiwan University Hospital69
- University of Minnesota63
Where studies are running
- California675
- Massachusetts305
- New York294
- Florida277
- Texas270
- Maryland245
- Alabama213
- Arizona211
- Illinois193
- Pennsylvania177
Recruiting studies12,495 total
- NCT07420296RecruitingPhase 3
Modified zipper therapy for AQP4-positive neuromyelitis optica
This trial tests a new treatment called modified zipper therapy for people with neuromyelitis optica spectrum disorder (NMOSD) who have a specific antibody (AQP4-IgG) in their blood. It aims to stop a recent attack and improve recovery.
TianjinAges 18–80 - NCT07420374Recruiting
Outpatient stroke care for older patients
This study tests whether older people with minor strokes or warning signs can be safely treated at home or in an outpatient clinic instead of staying in the hospital. It may be a good fit if you recently had a mild stroke and do not need complex medical care.
HeidelbergAges 60 years+ - NCT07420400Recruiting
Detecting heart shunts without needles
This trial uses a specialized ultrasound test (TEE with bubble study) to find a small opening in the heart called a PFO. It may help people who need this test to check for causes of certain health problems.
La Jolla, CaliforniaAges 18 years+ - NCT07420829Recruiting
Emotions and development in preschoolers
This study looks at how emotions and thinking skills develop in children aged 3 to 6 who go to preschool. The goal is to understand what affects a child's growth and to find better ways to support them.
Gdansk, Pomeranian VoivodeshipAges 3–6 - NCT07421453Recruiting
Better recovery plan for draining brain blood clots
This trial is testing a new, step-by-step care plan (called an enhanced recovery pathway) for people who need a small hole drilled in their skull to drain a slow-growing blood clot (chronic subdural hematoma). The goal is to see if this organized approach helps patients recover faster and feel better.
LeuvenAges 18 years+ - NCT07421960Recruiting
Periodontitis and sleep quality study
This study looks at how gum disease (periodontitis) might be related to sleep quality. It compares people with healthy gums to those with gum disease.
Istanbul, IstanbulAges 18–65 - NCT07422675RecruitingPhase 1
Study of a new treatment for Parkinson's with motor fluctuations
This study tests a new single-dose treatment for Parkinson's disease to see if it can help reduce 'off' time—when medication wears off and symptoms return. It is for people who experience motor fluctuations and are already on a stable medication routine.
Englewood, ColoradoAges 40–80 - NCT07422857RecruitingPhase 3
A PET scan for detecting signs of Alzheimer's
This trial uses a new type of PET scan to look for specific proteins in the brain that are linked to Alzheimer's disease. It will help doctors see how these proteins relate to cognitive decline and compare scans from people with normal thinking to those with memory problems.
Wuhan, HubeiAges 50 years+ - NCT07423026Recruiting
Remote study using technology to track DMD in young boys
This study uses remote technology, like apps or wearable devices, to monitor motor skills and development in boys with Duchenne muscular dystrophy (DMD). It aims to find better ways to measure how the disease progresses over time without requiring frequent clinic visits.
OxfordAges 1–3 - NCT07423195Recruiting
Cannabis use during wisdom tooth removal study
This study looks at how cannabis use affects pain and recovery after wisdom tooth surgery. If you are 16 or older and need a lower wisdom tooth removed, you may be able to join.
Ann Arbor, MichiganAges 16–99 - NCT07423377Recruiting
Vibration device for fibromyalgia pain
This trial tests if a device that delivers small vibrations to your ear can help reduce pain from fibromyalgia. You'll use the device as directed and answer online questions about your pain before and after.
New York, New YorkAges 18 years+ - NCT07423390RecruitingPhase 3
Vitamin B12 to prevent nerve damage from chemo
This trial tests if taking mecobalamin (a form of vitamin B12) can prevent or reduce nerve pain and numbness caused by taxane chemotherapy. It may help people getting chemo for several types of cancer.
Xining, QinghaiAges 18 years+ - NCT07423650RecruitingPhase 4
Continuous Nefopam infusion after pancreas surgery
This trial tests if giving a steady dose of a painkiller called nefopam through an IV can help manage pain after a Whipple procedure (pancreatoduodenectomy). It aims to see if this approach reduces the need for other pain medications and improves recovery.
Cluj-Napoca, ClujAges 18–80 - NCT07423988Recruiting
Sleep changes at high altitude for Pic du Midi staff
This study looks at how sleep quality changes when you work overnight at high altitude (2877m) at the Pic du Midi observatory, compared to sleeping at home. It helps understand the effects of high-altitude work on rest.
Toulouse, OuiAges 18–65 - NCT07424027Recruiting
Central vein sign in multiple sclerosis extension study
This study is for people already in the CAVS-MS study. It uses MRI scans to look at a specific sign in the brain that may help diagnose multiple sclerosis.
Los Angeles, CaliforniaAges 18–65 - NCT07424365Recruiting
Vagus nerve stimulation for thinking skills in health and Parkinson's
This study explores whether vagus nerve stimulation (a gentle electrical pulse that travels through a nerve in your ear) can boost thinking and decision-making skills in healthy people and those with Parkinson's disease. It involves a noninvasive device that stimulates the ear, and you may participate if you meet certain health criteria.
Aurora, ColoradoAges 18–65 - NCT07424846RecruitingPhase 2/Phase 3
Xylitol gum to prevent gum disease and early birth
This trial tests if chewing xylitol gum during pregnancy can reduce gum disease and preterm birth. You would chew gum after meals and attend dental visits and follow-ups.
LilongweAges Any age - NCT07424924Recruiting
Walking, activity, and sleep study for Parkinson's
This study looks at how walking, daily activity, and sleep are connected in Parkinson's disease. It compares people with Parkinson's to healthy volunteers to understand these links better.
IstanbulAges 40–75 - NCT07425457Recruiting
Cold nerve treatment before knee replacement surgery
This trial tests a cold therapy on nerves before knee replacement to reduce pain. It may help you recover with less discomfort after surgery.
AthensAges 18 years+ - NCT07425652Recruiting
Physiotherapy methods for fibromyalgia pain
This study tests different physiotherapy techniques to help women with fibromyalgia manage pain and improve daily function. It compares several hands-on therapies to find the most effective approach.
AnkaraAges 18–65 - NCT07425756Recruiting
Nerve stimulation for arm movement after stroke
This trial tests whether combining two types of nerve stimulation (one on the ear, one on the arm) can improve arm and hand movement after a stroke. It's for people who had a stroke at least 6 months ago and still have some but not full use of their affected arm.
KowloonAges 50–75 - NCT07426848Recruiting
Occupational therapy group for brain tumor patients
This study tests a group-based occupational therapy program to help people with primary brain tumors who are undergoing chemotherapy or other anti-cancer treatments. The goal is to improve daily activities and quality of life.
Dublin, BeaumontAges 18 years+ - NCT07426991Recruiting
Multiple sclerosis, thinking, sleep, and tiredness study
This study looks at how multiple sclerosis (MS) affects your thinking, sleep, and tiredness. It compares people with MS who have at least mild fatigue to people without MS who also have sleep problems, to understand these issues better.
DüsseldorfAges 18–79 - NCT07427446RecruitingPhase 4
Calming drugs for children after heart catheterization
This trial compares two combinations of sedative medicines (dexmedetomidine with midazolam versus ketamine with midazolam) to see which better prevents confusion or agitation when a child wakes up after a heart catheterization procedure. It may help your child recover more calmly.
CairoAges 2–6
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,497 recruiting neurology studies from the U.S. registry right now, out of 19,911 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.