Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,497 recruiting studies in this area right now.
By phase
- Not applicable9,839
- Phase 2787
- Phase 1573
- Phase 3531
- Phase 4344
- Phase 1/Phase 2304
- Phase 2/Phase 3119
Top conditions
- Stroke856
- Parkinson Disease424
- Alzheimer Disease341
- Multiple Sclerosis341
- Dementia228
- Ischemic Stroke201
- Epilepsy196
- Insomnia156
- Obstructive Sleep Apnea155
- Traumatic Brain Injury154
- Spinal Cord Injuries151
- Sarcopenia149
- Acute Ischemic Stroke141
- Cerebral Palsy129
- Mild Cognitive Impairment128
- Migraine113
- Pain Management113
- Amyotrophic Lateral Sclerosis107
Leading sponsors
- Beijing Tiantan Hospital135
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic98
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University71
- National Taiwan University Hospital69
- University of Minnesota63
Where studies are running
- California675
- Massachusetts305
- New York294
- Florida277
- Texas270
- Maryland245
- Alabama213
- Arizona211
- Illinois193
- Pennsylvania177
Recruiting studies12,495 total
- NCT07427537Recruiting
Studying nerve damage from chemotherapy in colorectal and lung cancer patients
This study looks for small molecules in the blood that might predict nerve damage caused by certain chemotherapies. If you have colorectal or lung cancer and are starting a specific chemo plan, this trial could help researchers understand why some people get nerve problems and others don't.
Clermont-FerrandAges 18 years+ - NCT07427511Recruiting
Rehab program for stroke recovery
This study tests a rehabilitation program for people who still have arm or leg trouble after a stroke. It aims to see if intensive daily training can improve movement and function.
Vitznau, Canton of LucerneAges 18–85 - NCT07427563Recruiting
Cerebellar deep brain stimulation for ataxia
This trial tests whether stimulating a part of the brain called the cerebellum with a device can help improve balance and coordination in people with primary ataxia (a movement disorder you were born with or inherited). It aims to see if this treatment is safe and effective over one year.
Toronto, OntarioAges 20–70 - NCT07428161Recruiting
Task-oriented circuit training for arm recovery after stroke
This trial tests whether a specific type of exercise program, called task-oriented circuit training, can improve arm and hand function in people who have had a stroke. It may be an option if you have some movement in your wrist and fingers.
Sivas, Sivas/CenterAges 18–65 - NCT07428811Recruiting
Mirror therapy for post-stroke shoulder and hand problems
This trial tests whether task-based mirror therapy can help improve shoulder and hand function in people who have had a stroke less than 6 months ago. It focuses on those with moderate to severe stroke symptoms but without severe muscle stiffness or cognitive issues.
Lahore, Punjab ProvinceAges 45–75 - NCT07428824Recruiting
Action observation with sound for stroke recovery
This study tests whether watching movements and listening to sounds at the same time can help improve walking and moving after a stroke. It is for people who are at least 6 months past their stroke and can already walk a bit.
Lahore, Punjab ProvinceAges 40–60 - NCT07428863Recruiting
Jump rope for foot health in Down syndrome
This study tests if jumping rope can help improve foot arch alignment in children with Down syndrome who have flat feet. It may offer a simple, fun way to strengthen feet and reduce foot problems.
Lahore, Punjab ProvinceAges 4–15 - NCT07428928Recruiting
Play-based hand therapy for cerebral palsy children
This trial tests whether playful hand and nerve exercises can improve grip strength and hand use in children with cerebral palsy. It may help children who have trouble with fine motor tasks.
Lahore, Punjab ProvinceAges 6–12 - NCT07429240RecruitingPhase 1/Phase 2
Gene editing trial for Duchenne muscular dystrophy (ages 2-7)
This trial tests a new gene editing treatment called PBGENE-DMD for boys with Duchenne muscular dystrophy (DMD) whose genetic mutation falls within a specific range of the dystrophin gene (exons 45-55). The goal is to see if it is safe and can help improve muscle function.
Little Rock, ArkansasAges 2–7 - NCT07429188Recruiting
Study of upper-limb assistive device users
This study looks at how well upper-limb assistive devices (like robotic arms) work for people who use them and for their caregivers. You and your caregiver can help by sharing your experiences in video interviews.
PerpignanAges 18 years+ - NCT07429305Recruiting
Nerve stimulation and standing for spinal cord injury
This trial tests whether combining a nerve stimulation therapy with standing exercises can improve bladder and bowel function after a spinal cord injury. It may help people who have nerve-related bladder problems.
Vancouver, British ColumbiaAges 19 years+ - NCT07429422Recruiting
Precise Radiation for Spine Tumors
This trial is testing a very precise radiation technique called SBRT for tumors that have spread to the spine. It aims to see if this approach can treat the tumor effectively while reducing side effects.
LjubljanaAges 18 years+ - NCT07429578Recruiting
Brain stimulation for anxiety and insomnia
This study tests whether a gentle, non-invasive brain stimulation technique (tACS) can help people who have both generalized anxiety and long-term sleep problems. It aims to see if this treatment can reduce anxiety and improve sleep.
São Paulo, São PauloAges 18–65 - NCT07429448RecruitingPhase 1
Numbing medicine for pain after appendix removal
This trial tests whether numbing medicine (bupivacaine) placed into the belly during an open appendix removal helps reduce pain after surgery, compared to a placebo (a shot with no medicine).
Lahore, Punjab ProvinceAges 20–60 - NCT07429916RecruitingEarly Phase 1
Ketamine for shoulder pain after weight loss surgery
This trial tests if a single dose of ketamine, given during surgery, can reduce common shoulder pain after laparoscopic gastric sleeve surgery. If you are having this weight-loss procedure and meet the weight and health criteria, this study may help improve your recovery.
IrbidAges 18–60 - NCT07430046RecruitingPhase 2
Testing mirtazapine for breathing problems in Rett syndrome
This study tests whether the drug mirtazapine can reduce breathing issues in females with Rett syndrome. Participants must have a confirmed MECP2 mutation and specific breathing dysfunction like breath holding or hyperventilation.
GenovaAges 5–40 - NCT07430150Recruiting
Long-term effects of oxygen therapy on thinking after brain injury
This study checks if hyperbaric oxygen therapy (breathing pure oxygen in a special chamber) has lasting benefits for thinking skills in people who have had a traumatic brain injury.
ZrifinAges 18 years+ - NCT07430761Recruiting
Stigma and tremor suppression in essential tremor
This study looks at how stigma (feeling embarrassed or judged) affects people with essential tremor who are planning to have a focused ultrasound procedure to reduce their tremor. It aims to understand feelings before and after treatment.
Dallas, TexasAges 18 years+ - NCT07431151Recruiting
Virtual reality training for balance after stroke
This study tests if using virtual reality headset games can help improve your balance, walking, daily activities, and quality of life after a recent stroke. If you join, you will do special balance and walking exercises with virtual reality.
Ankara, ÇankayaAges 18 years+ - NCT07432204Recruiting
Therapeutic music listening after stroke
This trial tests whether listening to music can help reduce anxiety and depression in people who have had a stroke within the past 3 months. It is designed for those who are experiencing significant emotional distress after their stroke.
PaviaAges 18 years+ - NCT07432321Recruiting
Spinal cord injury trial testing spinal stimulation and arm training
This trial tests whether combining spinal cord stimulation with arm and hand exercises can improve strength and function in people with chronic spinal cord injury. It may help you regain more control in your daily activities.
Singapore, SingaporeAges 21–80 - NCT07432711Recruiting
Liposomal bupivacaine for pain after lung surgery
This trial tests if a long-acting numbing medicine called liposomal bupivacaine can reduce pain after video-assisted lung surgery. It aims to help patients feel better after the procedure with less need for other painkillers.
Beijing, Beijing MunicipalityAges 18–64 - NCT07432750Recruiting
Osteopathic manipulation vs. wrist brace for carpal tunnel
This study tests whether osteopathic manipulation (a gentle hands-on treatment) works better than wearing a wrist brace for people with mild to moderate carpal tunnel syndrome. If you have mild or moderate carpal tunnel and haven't had surgery, this trial might help find a non-surgical option.
Old Westbury, New YorkAges 18 years+ - NCT07432789Recruiting
Testing a motion app for children with cerebral palsy
This study tests a smartphone app that measures how children with cerebral palsy move. It aims to see if the app can accurately track motor abilities, which could help doctors and families monitor progress more easily.
DijonAges 6–18
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,497 recruiting neurology studies from the U.S. registry right now, out of 19,911 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.