Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,516 recruiting studies in this area right now.
By phase
- Not applicable9,855
- Phase 2786
- Phase 1573
- Phase 3533
- Phase 4344
- Phase 1/Phase 2305
- Phase 2/Phase 3120
Top conditions
- Stroke852
- Parkinson Disease423
- Alzheimer Disease341
- Multiple Sclerosis340
- Dementia230
- Ischemic Stroke202
- Epilepsy197
- Insomnia156
- Obstructive Sleep Apnea156
- Traumatic Brain Injury156
- Spinal Cord Injuries152
- Sarcopenia151
- Acute Ischemic Stroke141
- Cerebral Palsy129
- Mild Cognitive Impairment128
- Migraine112
- Pain Management112
- Amyotrophic Lateral Sclerosis106
Leading sponsors
- Beijing Tiantan Hospital134
- Riphah International University127
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic98
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development92
- Hospices Civils de Lyon80
- Johns Hopkins University71
- National Taiwan University Hospital71
- University of Minnesota65
Where studies are running
- California678
- Massachusetts307
- New York295
- Florida274
- Texas271
- Maryland245
- Alabama214
- Arizona209
- Illinois193
- Pennsylvania177
Recruiting studies12,514 total
- NCT04100486Enrolling by invitation
Testing a noninvasive device to measure your body signals
This study uses a noninvasive bioelectronic device to record your body’s automatic (involuntary) signals. The goal is to see how well the device can analyze these signals and how your body responds in a controlled setting.
Manhasset, New YorkAges 18–60 - NCT04095026Enrolling by invitation
Brain recording and stimulation to improve memory
This study tests a brain-recording and brain-stimulation approach to help improve memory. It is offered to adults who are already enrolled in a specific epilepsy surgery program and can safely complete memory-related tasks.
Bethesda, MarylandAges 18–65 - NCT04043442Enrolling by invitationPhase 2
Brain stimulation study for alcohol use with mild brain injury
This trial tests a type of brain stimulation to help with day-to-day functioning in people who have alcohol use disorder and a history of mild traumatic brain injury. It also uses brain and symptom testing to see who may benefit most and why.
Hines, IllinoisAges 22–65 - NCT04042532Enrolling by invitation
Theta-burst brain stimulation for younger-onset Alzheimer’s
This trial tests whether a form of brain stimulation (theta-burst stimulation) can improve thinking and memory in people with younger-onset Alzheimer’s. It also compares results with people without dementia who meet similar age and health requirements.
Taoyuan, GuishanAges 50–75 - NCT04002505Enrolling by invitation
Study for low-risk head injury after a bump to the head
This trial studies people with a recent, blunt head injury who are considered low risk and may be getting a head CT scan. It may help improve how doctors decide when CT scans are needed after a concussion or possible brain bleeding.
Rochester, MinnesotaAges 18–65 - NCT03914664Enrolling by invitation
Brain and sensation study in adults with Tourette syndrome
This study looks at brain activity and how sensory experiences feel in adults with Tourette syndrome. It compares you to carefully matched adults without neurologic or psychiatric conditions to understand what is different in the brain.
Nashville, TennesseeAges 18 years+ - NCT03862274Enrolling by invitation
Study of development in children with CLN2 due to TPP1 changes
This study looks at how children’s development progresses in CLN2 disease caused by a specific enzyme problem (TPP1). It may help doctors better understand outcomes and guide future care for children with this diagnosis.
Columbus, OhioAges Any age - NCT03836300Enrolling by invitation
Parent-infant coaching for families with young diagnoses
This study tests a parent-and-infant coaching program for babies and caregivers. It aims to see whether the program helps after an early diagnosis when English is used at home.
Research Triangle Park, North CarolinaAges Up to 99 years - NCT03815656Enrolling by invitation
Closed-loop deep brain stimulation for Parkinson’s medication side effects
This study tests a “smart,” closed-loop deep brain stimulation (DBS) system that adjusts stimulation based on your brain signals. It’s designed for people with Parkinson’s who get troubling medication side effects, with the hope of improving symptoms more smoothly.
Durham, North CarolinaAges 18–75 - NCT03702127Enrolling by invitation
Brain electrode monitoring to plan seizure surgery
This study uses electrodes placed in the brain to record brain activity for about 2 weeks with EEG monitoring. It helps doctors decide whether you may benefit from surgery to remove the seizure-causing brain area.
Iowa City, IowaAges 18 years+ - NCT03687710Enrolling by invitation
Alzheimer’s registry for people with memory concerns or risk
This is a research registry that helps doctors compare how different memory and Alzheimer’s risk groups change over time. It may help researchers learn which people are more likely to develop Alzheimer’s and how to better track early changes.
New York, New YorkAges 18–99 - NCT03685188Enrolling by invitationPhase 4
Oxycodone and sufentanil pain medicine for hip surgery
This trial tests whether using oxycodone and sufentanil helps control pain during one-sided hip surgery. It’s meant to see how well these pain medicines work and whether they are safe for patients in this setting.
Chengdu, SichuanAges 18 years+ - NCT03623672Enrolling by invitation
Study for early signs of Parkinson-related brain changes
This study enrolls people with idiopathic REM sleep behavior disorder, a sleep problem that can come before Parkinson’s disease or related conditions. It aims to better understand early (“prodromal”) changes so future treatments can be targeted earlier.
Sun City, ArizonaAges 18 years+ - NCT03618186Enrolling by invitationPhase 2
Brain scan study for African Americans age 30+
This Phase 2 study uses brain imaging (including PET and MRI) to learn more about brain changes. It may help researchers improve how brain patterns are measured and understood, which could guide future care.
Jacksonville, FloridaAges 30 years+ - NCT03589846Enrolling by invitation
Muscle stimulation during a sleep endoscopy test
This trial studies whether muscle stimulation during DISE (a procedure to look at your airway while you’re sedated) can help people with obstructive sleep apnea who can’t tolerate CPAP. Your DISE is part of routine care, and the study adds a muscle stimulation step to see if it changes what’s happening in the throat.
Nashvile, TennesseeAges 18 years+ - NCT03582488Enrolling by invitationPhase 4
Tracking brain changes in probable Lewy body dementia
This trial follows people with probable Lewy body dementia over several years to see how the brain changes on MRI and on memory/thinking tests. It may help researchers understand disease progression and improve future care for Lewy body dementia.
Jacksonville, FloridaAges 18 years+ - NCT03511846Enrolling by invitationPhase 1
Pain biomarker study for headache or back nerve pain
This study looks at measurable “pain signals” (biomarkers) in people with certain headache disorders or lumbar nerve pain, and compares them with healthy people. It may help researchers better understand what drives pain and how it can be detected.
Houston, TexasAges 18 years+ - NCT03456089Enrolling by invitation
Measure bladder pressure with an external device during testing
This trial checks whether a new external device can measure bladder pressure accurately compared with the standard bladder test called urodynamics. If you have a neurogenic bladder and are already scheduled for urodynamics, this study may help improve how bladder pressure is measured in routine care.
Iowa City, IowaAges 1–99 - NCT03414242Enrolling by invitation
Neck and brain tests after a sports head or neck injury
This study looks at how sports-related injuries may affect thinking and how well your neck moves and feels strong. You may be eligible if you’re an athlete and can do simple neck movement and strength checks.
Scottsdale, ArizonaAges 12–30 - NCT03413566Enrolling by invitation
Studying health issues in children with cerebral palsy
This study is looking at how common different health problems are in children with cerebral palsy, and which problems often happen together. It may help clinicians plan better care by understanding the most frequent additional needs.
Ages 5–18 - NCT03395509Enrolling by invitation
Free screening program for diabetes and heart risks
This study looks at how well and how cost-effective a combined health screening is for diabetes and cardiovascular (heart and blood vessel) risks. You may be invited to attend screening around your 67th birthday.
ViborgAges 67–67 - NCT03389100Enrolling by invitationPhase 2
Tau PET brain scan study for people without dementia
This trial studies how tau (a protein linked to Alzheimer’s and related conditions) shows up on a special brain scan called tau PET. It also uses MRI and blood work to understand brain changes and who may be at risk, helping researchers improve future diagnosis.
New York, New YorkAges 55–69 - NCT03384927Enrolling by invitation
Dairy intake study for muscle stiffness in spasticity
This trial looks at whether eating dairy can reduce spasticity, or muscle stiffness/tightness. It’s testing dairy as an add-on by comparing your muscle symptoms and treatment goals during the study.
Glostrup MunicipalityAges Any age - NCT03360227Recruiting
Registry after heart device implantation planning
This is a registry study that records information from people before they get a heart-related device implanted. It may help doctors understand how the team’s tests and planning relate to the procedure and outcomes later on.
DüsseldorfAges 18–80
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,516 recruiting neurology studies from the U.S. registry right now, out of 20,061 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.