Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,406 recruiting studies in this area right now.
By phase
- Not applicable9,740
- Phase 2783
- Phase 1576
- Phase 3534
- Phase 4342
- Phase 1/Phase 2307
- Phase 2/Phase 3124
Top conditions
- Stroke841
- Parkinson Disease427
- Alzheimer Disease342
- Multiple Sclerosis341
- Dementia227
- Ischemic Stroke201
- Epilepsy197
- Obstructive Sleep Apnea156
- Insomnia154
- Spinal Cord Injuries153
- Traumatic Brain Injury150
- Sarcopenia149
- Acute Ischemic Stroke138
- Cerebral Palsy131
- Mild Cognitive Impairment130
- Migraine113
- Pain Management113
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing93
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California681
- Massachusetts299
- New York292
- Florida275
- Texas265
- Maryland246
- Arizona212
- Alabama210
- Illinois188
- Pennsylvania177
Recruiting studies12,404 total
- NCT07183033Enrolling by invitation
VR brain training for older adults with mild memory and health issues
This trial uses virtual reality exercises to see if they can help improve brain function in older adults who have some memory concerns and physical frailty. Researchers want to know if a fun, interactive VR program can strengthen connections in the brain and improve daily life.
Beijing, Beijing MunicipalityAges 60 years+ - NCT07631169Recruiting
Action Observation Therapy for Stroke Hand Recovery
This study tests whether watching and practicing hand movements (with one or both hands) can help improve hand function and grip strength in people who had a stroke on the left side of their brain. The therapy uses observation and practice to retrain the brain and hand after stroke.
Karabük, MerkezAges 18 years+ - NCT07175753Enrolling by invitation
Chiropractic Care for Sports Concussion in Athletes
This trial tests whether chiropractic care can help athletes at Life University recover from a sports-related concussion. It focuses on reducing symptoms like headache, dizziness, and slower reaction times.
Marietta, GeorgiaAges 18–40 - NCT06839547Recruiting
Testing a new drug with radiation for advanced breast cancer brain tumors
This study looks at how well a new anti-tumor drug works when given along with radiation therapy for people whose advanced breast cancer has spread to the brain. It may help the radiation work better and control the cancer longer.
BeijingAges 18 years+ - NCT06072378Recruiting
Decision-making and memory study with brain recordings
This study looks at how the brain makes decisions and forms memories. It uses brain recordings from patients already having surgery for epilepsy to understand these processes.
New Brunswick, New JerseyAges 18–65 - NCT07158229Recruiting
Long-term effects of NMDAR encephalitis
This study follows adults with NMDAR encephalitis over time to understand its long-term effects. It uses online questionnaires, so you need internet access at home.
BronAges 18 years+ - NCT06555900Recruiting
Predicting brain pressure spikes in injured patients using AI
This study is testing if an artificial intelligence program can predict dangerous increases in pressure inside the skull of people with brain injuries. If successful, it could help doctors treat these episodes sooner.
BrestAges 18–99 - NCT07150559Recruiting
Arch-clamping under mild cooling for acute aortic dissection
This trial tests a surgical technique called arch-clamping under mild hypothermia (cooling the body slightly during surgery) to treat acute type A aortic dissection. It may help patients who need immediate total aortic arch replacement.
Beijing, Beijing MunicipalityAges 18–70 - NCT06865222Recruiting
Magnetic brain stimulation for lingering COVID symptoms
This study tests whether a special type of magnetic stimulation (called TMS) can help with lingering symptoms after COVID-19, such as loss of smell, ringing in the ears, or fatigue. The treatment is safe and non-invasive, using a magnet placed near your head.
Rochester, MinnesotaAges 18–65 - NCT07270887Recruiting
Can gentle arm cuffs protect your heart and brain over time?
This trial tests if using a blood pressure cuff on your arm in short cycles can help prevent future heart attacks, strokes, and other problems in people at very high risk. You may qualify if you've already had a major heart or blood vessel event.
ShenyangAges 40 years+ - NCT07142044RecruitingPhase 1/Phase 2
Testing EC5026 for Parkinson's disease
This study tests a new oral medication called EC5026 for Parkinson's disease. It aims to see if the drug is safe and if it might help control symptoms when added to your current levodopa treatment.
Sacramento, CaliforniaAges 50–80 - NCT07132814Recruiting
Testing abuse potential of five oral nicotine products
This study tests how much people might want to use five different types of modern oral nicotine products (like pouches or lozenges) compared to smoking their usual cigarette. It helps researchers understand if these products could be less addictive than cigarettes.
Overland Park, KansasAges 21–60 - NCT06060912Recruiting
Comparing two heart devices to prevent stroke in atrial fibrillation
This study compares two devices (LAmbre and AMPLATZER Amulet) that are placed in the heart to prevent strokes in people with atrial fibrillation who cannot take blood thinners. If you join, you will be randomly assigned to get one of the two devices.
Munich, BavariaAges 18–100 - NCT05755399Recruiting
Ultrasound test during brain tumor surgery
This study checks whether a special, painless ultrasound technique can help measure a brain tumor during planned brain surgery. It may help doctors understand tumor location and behavior more accurately while you’re already in the operating room.
Minneapolis, MinnesotaAges 18 years+ - NCT04548817Recruiting
Registry for neurocutaneous and brain melanocytosis
This trial is a registry that collects information from people with certain pigment-related conditions affecting the skin and/or the brain. It helps doctors better understand the condition and may improve future care.
Boston, MassachusettsAges Any age - NCT06230796Recruiting
Electrical stimulation cycling for stroke recovery
This trial tests whether using a special bike that delivers mild electrical pulses to your leg muscles can help improve walking after a stroke. If you have weakness on one side from a stroke that happened 3 to 12 months ago, this study may be a good fit for you.
Saint-Didier-au-Mont-d'Or, FranceAges 18 years+ - NCT05697588Recruiting
Study blood and brain markers from mild memory loss to dementia
This study looks for “biomarkers” (measurable signs from blood and brain tests) that may help predict who with mild cognitive impairment (MCI) could later develop dementia. Results may help doctors spot risk earlier and better plan care.
Beijing, Beijing MunicipalityAges 50–85 - NCT07119788Recruiting
Haskap berry supplement for cognitive health
This study tests whether a supplement made from haskap berries can help improve cognitive health in older adults. If you are 50 or older, eat few fruits and vegetables, and are generally healthy, you may be able to join.
ReadingAges 50 years+ - NCT06672354Recruiting
Virtual reality vs. exercises for balance in older adults
This trial tests whether a fun virtual reality game (like a video game you do standing up) can improve balance and walking better than a set of simple exercises. It is for older adults who can still walk on their own but want to stay steady on their feet.
IslamabadAges 55 years+ - NCT07108712Recruiting
Using brain MRI to detect early white matter disease
This trial studies whether a special type of MRI can find brain white matter changes early. It might help people who have early symptoms or are at risk for diseases affecting the brain's wiring.
CairoAges 18–80 - NCT06855407Recruiting
Blood pressure and brain blood flow during anesthesia study
This study looks at how blood pressure medicines affect blood flow to the brain during general anesthesia for planned surgery. It may help doctors understand how to better manage care during operations.
UmeåAges 50–80 - NCT06848257Enrolling by invitation
Posture exercises for Parkinson's disease
This trial studies whether specific posture exercises can help people with Parkinson's disease improve their balance and movement. It is designed for people who are in the early to moderate stages of the disease and do not have other major health issues.
AnkaraAges 50 years+ - NCT05765981RecruitingEarly Phase 1
Testing a gene therapy for AADC deficiency in young children
This early-stage trial tests VGN-R09b, a gene therapy, given to children with AADC deficiency who are not doing well on standard medicines. It aims to improve symptoms and quality of life by addressing the underlying cause of AADC deficiency.
Shanghai, No. 1678, Dongfang Road, Pudong New Area, ShanghaiAges 2–7 - NCT07092995Enrolling by invitation
Understanding freezing of gait in Parkinson's using VR and brain signals
This study uses virtual reality and brain recordings from your DBS device to understand why some people with Parkinson's experience freezing of gait (feeling like your feet are stuck to the ground). You'll be asked to walk in a safe VR environment while researchers monitor your brain activity.
Los Angeles, CaliforniaAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,406 recruiting neurology studies from the U.S. registry right now, out of 19,323 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.